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BETA
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  • HACD3
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:62.3 nTPM
HPA Brain:143.7 nTPM
GTEx:62.3 nTPM
FANTOM5:114.5 Scaled Tags Per Million
Macaque:127.4 nTPM
Mouse:95.4 nTPM
Rat:97.1 nTPM
Pig:109.8 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 280
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 240
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

143.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 105.8
1870 Female, age 42, unknown 129.3
2411 Female, age 72, unknown 118.7
1827 Male, age 72, unknown 118.6
1833 Male, age 53, unknown 108.8
2828 Female, age 72, unknown 105.0
2586 Male, age 75, left hemisphere 103.0
1830 Male, age 51, unknown 99.4
2019 Male, age 18, unknown 99.1
2219 Male, age 76, both hemispheres 98.8
2666 Male, age 74, left hemisphere 77.2
Dorsal raphe nucleus
nTPM: 131.2
2298 Female, age 72, unknown 149.3
2047 Male, age 72, unknown 139.6
2750 Male, age 76, both hemispheres 129.4
2016 Female, age 72, unknown 120.4
1828 Male, age 53, unknown 117.5
Inferior colliculus
nTPM: 123.6
2097 Female, age 72, unknown 139.5
2849 Male, age 72, unknown 122.4
1848 Female, age 42, unknown 121.9
1890 Male, age 53, unknown 110.7
Median raphe nucleus
nTPM: 143.7
2220 Male, age 76, midline 143.7
Periaquaductal grey, anterior
nTPM: 118.1
1947 Male, age 18, unknown 125.1
2502 Female, age 75, unknown 114.9
1795 Male, age 51, unknown 114.3
Periaquaductal grey, dorsal
nTPM: 126.4
1840 Male, age 53, unknown 145.8
2850 Male, age 76, both hemispheres 138.8
2464 Female, age 72, unknown 118.0
1831 Male, age 72, unknown 103.2
Periaquaductal grey, lateral
nTPM: 115.5
2140 Male, age 76, both hemispheres 126.5
2272 Male, age 74, both hemispheres 110.6
2053 Male, age 18, unknown 109.5
Pretectal area
nTPM: 118.6
2667 Female, age 75, unknown 147.2
2224 Female, age 72, unknown 131.6
2273 Male, age 74, both hemispheres 125.1
1817 Female, age 42, unknown 122.1
2825 Male, age 18, unknown 119.4
2007 Male, age 72, unknown 118.5
1816 Male, age 51, unknown 117.9
1944 Female, age 72, unknown 117.3
1815 Male, age 53, unknown 112.7
2316 Male, age 76, right hemisphere 98.4
2407 Male, age 75, both hemispheres 94.1
Red nucleus
nTPM: 98.8
1821 Female, age 72, unknown 124.4
1954 Female, age 42, unknown 109.9
2725 Female, age 75, unknown 106.8
2823 Male, age 76, right hemisphere 99.4
1904 Male, age 53, unknown 99.3
2769 Male, age 72, unknown 98.6
2227 Male, age 72, unknown 97.4
1865 Male, age 51, unknown 96.2
2785 Male, age 18, unknown 95.6
2503 Female, age 72, unknown 95.4
2584 Male, age 75, left hemisphere 83.0
2588 Male, age 74, left hemisphere 79.6
Substantia nigra
nTPM: 103.9
2241 Male, age 72, unknown 129.6
1916 Female, age 42, unknown 125.5
1889 Female, age 72, unknown 121.1
1851 Male, age 51, unknown 109.2
1941 Male, age 53, unknown 107.3
2409 Female, age 72, unknown 106.9
2699 Male, age 18, unknown 98.5
2583 Male, age 75, right hemisphere 83.9
2590 Female, age 75, unknown 78.9
2665 Male, age 74, both hemispheres 77.8
Superior colliculus
nTPM: 101.6
1895 Male, age 76, right hemisphere 112.9
2261 Male, age 18, unknown 111.7
1839 Male, age 51, unknown 107.7
2087 Female, age 72, unknown 107.6
1796 Male, age 53, unknown 106.1
2587 Male, age 74, left hemisphere 103.2
2664 Male, age 75, both hemispheres 102.6
2668 Female, age 75, unknown 98.9
1913 Female, age 42, unknown 84.9
1995 Male, age 72, unknown 80.5
Ventral tegmental area
nTPM: 112.1
2218 Male, age 76, both hemispheres 120.4
1915 Female, age 42, unknown 114.1
2410 Female, age 72, unknown 112.7
1942 Male, age 51, unknown 109.3
2223 Female, age 72, unknown 108.4
2021 Male, age 53, unknown 107.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 62.3
Samples: 183

Max nTPM: 124.1
Min nTPM: 25.5
Std nTPM: 18.7
Median nTPM: 60.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 124.1
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 116.3
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 111.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 98.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 98.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 98.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 96.4
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 95.6
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 94.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 93.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 93.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 92.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 91.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 91.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 90.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 90.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 89.7
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 89.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 88.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 88.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 87.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 86.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 86.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 86.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 85.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 85.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 84.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 84.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 83.2
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 82.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 81.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 80.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 80.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 80.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 80.0
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 79.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 79.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 78.6
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 78.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 78.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 78.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 77.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 77.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 77.1
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 75.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 74.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 73.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 73.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 73.2
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 72.6
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 72.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 72.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 71.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 70.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 70.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 70.0
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 69.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 68.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 68.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 68.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 68.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 67.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 67.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 67.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 67.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 66.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 66.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 66.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 65.7
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 65.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 65.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 65.2
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 65.1
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 64.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 64.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 64.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 63.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 63.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 63.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 62.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 62.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 62.3
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 62.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 62.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 61.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 61.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 61.0
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 60.7
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 60.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 60.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 60.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 60.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 60.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 59.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 59.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 59.2
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 58.9
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 58.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 58.8
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 58.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 58.5
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 58.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 58.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 58.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 57.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 57.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 56.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 56.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 55.8
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 55.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 55.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 54.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 54.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 54.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 53.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 53.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 52.8
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 52.7
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 52.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 52.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 52.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 52.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 51.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 51.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 51.6
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 51.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 51.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 51.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 51.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 51.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 51.1
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 50.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.6
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 50.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 50.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 50.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 50.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 49.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 49.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 48.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 48.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 47.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 47.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.5
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 47.1
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 46.6
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 44.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 44.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 44.3
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 43.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 43.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 43.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.2
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 42.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 42.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 42.3
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 42.2
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 42.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 41.9
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 41.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 41.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 40.0
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 39.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 39.2
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 38.7
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 38.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 37.9
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 37.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.1
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 35.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 33.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 32.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 32.8
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 32.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 29.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 28.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 28.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 27.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 27.4
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 25.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 25.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

114.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 114.5
FF:10158-103A5 76 years, female 114.5

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

127.4
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 127.4
Samples: 1

Max nTPM: 127.4
Min nTPM: 127.4
Sample A 127.4
Midbrain
nTPM: 110.9
Samples: 1

Max nTPM: 110.9
Min nTPM: 110.9
Sample A 110.9
Superior colliculi
nTPM: 100.3
Samples: 1

Max nTPM: 100.3
Min nTPM: 100.3
Sample A 100.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 109.8
Samples: 3

Max nTPM: 119.8
Min nTPM: 91.2
Sample A Female 118.3
Sample B Female 91.2
Sample C Male 119.8
Midbrain
nTPM: 108.4
Samples: 3

Max nTPM: 111.4
Min nTPM: 106.4
Sample B Female 106.4
Sample C Male 107.5
Sample D Male 111.4
Periaqueductal gray
nTPM: 104.2
Samples: 3

Max nTPM: 116.8
Min nTPM: 95.2
Sample B Female 100.7
Sample C Male 116.8
Sample D Male 95.2
Superior colliculi
nTPM: 97.2
Samples: 4

Max nTPM: 109.7
Min nTPM: 81.2
Sample A Female 109.7
Sample B Female 81.2
Sample C Male 102.7
Sample D Male 95.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 95.4
Samples: 4

Max nTPM: 99.2
Min nTPM: 92.9
Sample A 93.5
Sample B 92.9
Sample C 95.9
Sample D 99.2

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

97.1
Rat sample Sample description nTPM
Midbrain
nTPM: 97.1
Samples: 4

Max nTPM: 102.7
Min nTPM: 93.6
Sample A 93.6
Sample A 102.7
Sample A 97.8
Sample A 94.4

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