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BETA
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  • KCNQ2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:23.8 nTPM
HPA Brain:122.2 nTPM
GTEx:23.8 nTPM
FANTOM5:5.6 Scaled Tags Per Million
Macaque:22.1 nTPM
Mouse:75.0 nTPM
Rat:266.1 nTPM
Pig:40.0 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 120
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 120
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

122.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 89.1
2219 Male, age 76, both hemispheres 158.9
2586 Male, age 75, left hemisphere 109.2
2019 Male, age 18, unknown 103.9
2666 Male, age 74, left hemisphere 99.7
2828 Female, age 72, unknown 88.8
1827 Male, age 72, unknown 86.0
1870 Female, age 42, unknown 65.4
2411 Female, age 72, unknown 64.8
1830 Male, age 51, unknown 61.4
1833 Male, age 53, unknown 53.4
Dorsal raphe nucleus
nTPM: 74.0
2298 Female, age 72, unknown 94.1
2047 Male, age 72, unknown 90.2
2750 Male, age 76, both hemispheres 66.4
1828 Male, age 53, unknown 64.0
2016 Female, age 72, unknown 55.3
Inferior colliculus
nTPM: 85.0
2097 Female, age 72, unknown 98.5
1890 Male, age 53, unknown 96.4
1848 Female, age 42, unknown 76.1
2849 Male, age 72, unknown 69.0
Median raphe nucleus
nTPM: 98.7
2220 Male, age 76, midline 98.7
Periaquaductal grey, anterior
nTPM: 122.2
2502 Female, age 75, unknown 155.9
1795 Male, age 51, unknown 117.8
1947 Male, age 18, unknown 92.8
Periaquaductal grey, dorsal
nTPM: 85.7
1840 Male, age 53, unknown 97.4
1831 Male, age 72, unknown 90.8
2464 Female, age 72, unknown 87.6
2850 Male, age 76, both hemispheres 67.0
Periaquaductal grey, lateral
nTPM: 71.5
2140 Male, age 76, both hemispheres 79.3
2053 Male, age 18, unknown 69.0
2272 Male, age 74, both hemispheres 66.1
Pretectal area
nTPM: 103.4
1816 Male, age 51, unknown 167.0
1944 Female, age 72, unknown 147.5
2007 Male, age 72, unknown 142.6
1817 Female, age 42, unknown 121.0
2667 Female, age 75, unknown 110.2
1815 Male, age 53, unknown 102.4
2224 Female, age 72, unknown 88.6
2316 Male, age 76, right hemisphere 74.9
2825 Male, age 18, unknown 70.3
2407 Male, age 75, both hemispheres 66.1
2273 Male, age 74, both hemispheres 46.9
Red nucleus
nTPM: 58.2
2785 Male, age 18, unknown 100.5
2584 Male, age 75, left hemisphere 85.9
2588 Male, age 74, left hemisphere 58.9
2227 Male, age 72, unknown 57.8
2503 Female, age 72, unknown 56.3
1954 Female, age 42, unknown 54.3
2725 Female, age 75, unknown 53.2
1904 Male, age 53, unknown 52.0
2769 Male, age 72, unknown 48.4
2823 Male, age 76, right hemisphere 48.1
1865 Male, age 51, unknown 45.1
1821 Female, age 72, unknown 38.2
Substantia nigra
nTPM: 77.9
2665 Male, age 74, both hemispheres 118.7
1889 Female, age 72, unknown 113.8
1941 Male, age 53, unknown 93.5
1916 Female, age 42, unknown 89.5
1851 Male, age 51, unknown 78.6
2241 Male, age 72, unknown 72.5
2590 Female, age 75, unknown 66.2
2699 Male, age 18, unknown 53.1
2409 Female, age 72, unknown 49.0
2583 Male, age 75, right hemisphere 44.5
Superior colliculus
nTPM: 91.9
2087 Female, age 72, unknown 143.7
2664 Male, age 75, both hemispheres 107.3
1796 Male, age 53, unknown 106.1
2261 Male, age 18, unknown 103.8
1895 Male, age 76, right hemisphere 101.9
2587 Male, age 74, left hemisphere 81.0
1839 Male, age 51, unknown 70.9
1913 Female, age 42, unknown 70.8
2668 Female, age 75, unknown 70.8
1995 Male, age 72, unknown 62.9
Ventral tegmental area
nTPM: 85.5
2218 Male, age 76, both hemispheres 104.2
1942 Male, age 51, unknown 100.9
1915 Female, age 42, unknown 81.5
2021 Male, age 53, unknown 78.4
2223 Female, age 72, unknown 74.2
2410 Female, age 72, unknown 73.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 23.8
Samples: 183

Max nTPM: 131.5
Min nTPM: 1.2
Std nTPM: 17.1
Median nTPM: 21.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 131.5
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 101.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 95.0
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 76.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 61.0
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 50.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 50.2
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 49.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 48.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 46.8
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 46.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 46.5
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 46.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 45.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 42.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 42.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 41.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 41.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 40.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 40.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 40.5
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 39.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 39.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 37.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 37.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 37.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 36.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 35.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 35.6
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 35.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 35.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 35.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 35.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 35.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 35.1
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 34.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 34.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 34.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 33.9
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 33.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 33.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 33.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 33.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 33.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 33.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 32.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 32.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 32.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 32.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 31.9
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 31.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 30.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 30.3
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 29.7
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 29.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 29.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 29.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 28.9
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 28.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 28.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 28.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 28.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 27.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 27.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 27.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 27.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 27.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 26.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 26.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 26.4
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 26.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 26.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 25.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 25.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 25.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 24.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 24.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 24.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 24.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 24.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 22.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 22.8
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 22.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 22.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 22.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 22.5
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 22.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 22.1
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 22.0
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 21.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 21.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 21.5
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 21.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 20.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 20.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 20.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 19.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 19.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 19.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 18.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 18.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 18.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 18.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 18.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 17.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 17.7
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 17.6
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 17.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 16.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 16.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 16.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 16.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 16.3
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 16.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 15.5
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 15.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 14.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 14.8
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 14.7
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 14.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 14.3
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 14.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 14.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 13.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 13.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 13.8
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 13.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 13.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 13.2
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 13.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 13.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 13.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 12.5
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 12.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 11.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 11.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 11.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 11.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 11.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 11.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 11.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 10.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 10.8
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 10.8
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 10.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 10.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 10.1
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 10.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 9.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 9.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 9.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 9.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 8.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 8.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 8.2
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 8.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 7.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 7.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 7.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 7.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 7.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 6.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 6.7
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 6.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 6.3
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 6.3
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 6.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 5.8
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 5.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 5.6
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 5.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 3.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 3.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 3.7
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 3.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 3.4
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 3.2
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 1.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

5.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 5.6
FF:10158-103A5 76 years, female 5.6

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 9.8
Samples: 1

Max nTPM: 9.8
Min nTPM: 9.8
Sample A 9.8
Midbrain
nTPM: 14.3
Samples: 1

Max nTPM: 14.3
Min nTPM: 14.3
Sample A 14.3
Superior colliculi
nTPM: 22.1
Samples: 1

Max nTPM: 22.1
Min nTPM: 22.1
Sample A 22.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 23.5
Samples: 3

Max nTPM: 31.1
Min nTPM: 14.0
Sample A Female 25.4
Sample B Female 14.0
Sample C Male 31.1
Midbrain
nTPM: 40.0
Samples: 3

Max nTPM: 67.5
Min nTPM: 15.3
Sample B Female 15.3
Sample C Male 67.5
Sample D Male 37.2
Periaqueductal gray
nTPM: 15.3
Samples: 3

Max nTPM: 20.1
Min nTPM: 12.5
Sample B Female 13.4
Sample C Male 20.1
Sample D Male 12.5
Superior colliculi
nTPM: 26.2
Samples: 4

Max nTPM: 39.3
Min nTPM: 12.0
Sample A Female 23.1
Sample B Female 12.0
Sample C Male 39.3
Sample D Male 30.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 75.0
Samples: 4

Max nTPM: 82.3
Min nTPM: 64.0
Sample A 64.0
Sample B 82.3
Sample C 81.0
Sample D 72.8

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

266.1
Rat sample Sample description nTPM
Midbrain
nTPM: 266.1
Samples: 4

Max nTPM: 273.5
Min nTPM: 248.0
Sample A 273.5
Sample A 270.5
Sample A 272.3
Sample A 248.0

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