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BETA
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  • GSK3B
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:9.9 nTPM
HPA Brain:82.1 nTPM
GTEx:9.9 nTPM
FANTOM5:49.5 Scaled Tags Per Million
Macaque:95.6 nTPM
Mouse:96.4 nTPM
Rat:96.0 nTPM
Pig:106.2 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 420
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 500
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

82.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.7
2219 Male, age 76, both hemispheres 79.1
2666 Male, age 74, left hemisphere 72.3
2586 Male, age 75, left hemisphere 72.0
1827 Male, age 72, unknown 70.3
2828 Female, age 72, unknown 60.2
2411 Female, age 72, unknown 59.0
1833 Male, age 53, unknown 58.9
1830 Male, age 51, unknown 53.4
1870 Female, age 42, unknown 51.4
2019 Male, age 18, unknown 50.6
Dorsal raphe nucleus
nTPM: 59.8
2047 Male, age 72, unknown 65.2
2750 Male, age 76, both hemispheres 63.5
2298 Female, age 72, unknown 58.2
1828 Male, age 53, unknown 57.4
2016 Female, age 72, unknown 54.7
Inferior colliculus
nTPM: 62.4
2849 Male, age 72, unknown 66.8
1848 Female, age 42, unknown 65.6
2097 Female, age 72, unknown 60.8
1890 Male, age 53, unknown 56.5
Median raphe nucleus
nTPM: 82.1
2220 Male, age 76, midline 82.1
Periaquaductal grey, anterior
nTPM: 69.7
1947 Male, age 18, unknown 74.9
1795 Male, age 51, unknown 70.1
2502 Female, age 75, unknown 64.0
Periaquaductal grey, dorsal
nTPM: 58.7
2850 Male, age 76, both hemispheres 62.3
1831 Male, age 72, unknown 58.9
1840 Male, age 53, unknown 57.4
2464 Female, age 72, unknown 56.2
Periaquaductal grey, lateral
nTPM: 55.5
2272 Male, age 74, both hemispheres 56.2
2140 Male, age 76, both hemispheres 55.5
2053 Male, age 18, unknown 54.9
Pretectal area
nTPM: 61.8
1816 Male, age 51, unknown 74.5
1817 Female, age 42, unknown 71.8
2007 Male, age 72, unknown 68.9
1815 Male, age 53, unknown 68.3
2667 Female, age 75, unknown 67.2
2825 Male, age 18, unknown 64.7
1944 Female, age 72, unknown 61.8
2224 Female, age 72, unknown 60.8
2407 Male, age 75, both hemispheres 48.5
2316 Male, age 76, right hemisphere 48.3
2273 Male, age 74, both hemispheres 45.0
Red nucleus
nTPM: 54.2
2588 Male, age 74, left hemisphere 64.7
2503 Female, age 72, unknown 60.6
2584 Male, age 75, left hemisphere 60.3
2725 Female, age 75, unknown 58.4
1821 Female, age 72, unknown 57.9
1954 Female, age 42, unknown 53.5
2227 Male, age 72, unknown 51.1
2785 Male, age 18, unknown 51.1
1865 Male, age 51, unknown 49.5
2769 Male, age 72, unknown 47.9
1904 Male, age 53, unknown 47.6
2823 Male, age 76, right hemisphere 47.3
Substantia nigra
nTPM: 67.0
1916 Female, age 42, unknown 92.8
1941 Male, age 53, unknown 74.9
2665 Male, age 74, both hemispheres 74.6
2241 Male, age 72, unknown 69.7
1851 Male, age 51, unknown 67.7
2699 Male, age 18, unknown 66.7
1889 Female, age 72, unknown 65.6
2590 Female, age 75, unknown 60.2
2583 Male, age 75, right hemisphere 58.0
2409 Female, age 72, unknown 39.3
Superior colliculus
nTPM: 59.7
2664 Male, age 75, both hemispheres 71.5
1796 Male, age 53, unknown 68.3
2261 Male, age 18, unknown 66.4
2087 Female, age 72, unknown 65.0
1839 Male, age 51, unknown 63.5
1895 Male, age 76, right hemisphere 58.8
2668 Female, age 75, unknown 58.5
2587 Male, age 74, left hemisphere 53.1
1913 Female, age 42, unknown 48.6
1995 Male, age 72, unknown 43.7
Ventral tegmental area
nTPM: 66.1
2218 Male, age 76, both hemispheres 84.9
1915 Female, age 42, unknown 67.3
2410 Female, age 72, unknown 63.4
2021 Male, age 53, unknown 62.0
1942 Male, age 51, unknown 60.6
2223 Female, age 72, unknown 58.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 9.9
Samples: 183

Max nTPM: 26.1
Min nTPM: 4.7
Std nTPM: 3.8
Median nTPM: 8.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 26.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 24.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 22.3
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 21.6
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 19.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 19.7
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 19.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 18.8
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 18.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 17.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 16.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 16.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 16.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 15.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 15.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 15.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 15.2
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 15.0
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 14.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 14.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 14.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 14.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 14.2
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 14.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 14.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 13.9
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 13.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 13.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 13.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 13.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 13.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 13.2
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 13.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 13.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 12.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 12.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 12.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 12.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 12.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 12.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 11.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 11.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 11.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 11.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 11.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 11.5
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 11.4
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 11.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 11.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 11.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 11.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 11.0
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 11.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 11.0
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 11.0
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 11.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 10.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 10.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 10.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 10.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 10.6
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 10.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 10.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 10.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 10.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 10.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 10.0
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 10.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 9.9
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 9.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 9.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 9.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 9.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 9.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 9.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 9.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 9.4
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 9.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 9.3
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 9.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 9.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 9.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 9.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 8.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 8.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 8.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 8.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 8.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 8.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 8.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 8.5
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 8.5
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 8.5
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 8.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 8.4
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 8.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 8.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 8.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 8.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 8.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 8.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 8.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 8.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 8.2
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 8.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 8.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 8.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 8.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 8.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 8.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 8.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 7.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 7.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 7.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 7.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 7.8
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 7.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 7.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 7.7
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 7.7
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 7.6
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 7.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 7.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 7.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 7.4
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 7.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 7.4
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 7.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 7.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 7.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 7.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 7.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 7.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 7.1
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 7.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 7.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 7.0
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 7.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 7.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 7.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 6.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 6.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 6.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 6.9
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 6.8
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 6.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 6.7
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 6.7
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 6.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 6.7
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 6.6
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 6.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 6.5
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 6.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 6.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 6.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 6.3
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 6.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 6.2
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 6.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 6.2
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 6.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 6.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 6.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 6.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 6.0
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 5.8
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 5.8
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 5.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5.7
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 5.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5.4
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 5.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 5.1
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 4.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

49.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 49.5
FF:10158-103A5 76 years, female 49.5

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 82.1
Samples: 1

Max nTPM: 82.1
Min nTPM: 82.1
Sample A 82.1
Midbrain
nTPM: 87.2
Samples: 1

Max nTPM: 87.2
Min nTPM: 87.2
Sample A 87.2
Superior colliculi
nTPM: 95.6
Samples: 1

Max nTPM: 95.6
Min nTPM: 95.6
Sample A 95.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

106.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 106.2
Samples: 3

Max nTPM: 124.7
Min nTPM: 81.4
Sample A Female 112.5
Sample B Female 81.4
Sample C Male 124.7
Midbrain
nTPM: 104.4
Samples: 3

Max nTPM: 127.5
Min nTPM: 87.0
Sample B Female 87.0
Sample C Male 127.5
Sample D Male 98.6
Periaqueductal gray
nTPM: 87.4
Samples: 3

Max nTPM: 101.1
Min nTPM: 79.7
Sample B Female 81.5
Sample C Male 101.1
Sample D Male 79.7
Superior colliculi
nTPM: 87.8
Samples: 4

Max nTPM: 106.1
Min nTPM: 66.1
Sample A Female 87.3
Sample B Female 66.1
Sample C Male 106.1
Sample D Male 91.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

96.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 96.4
Samples: 4

Max nTPM: 104.0
Min nTPM: 86.0
Sample A 86.0
Sample B 94.0
Sample C 104.0
Sample D 101.6

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

96.0
Rat sample Sample description nTPM
Midbrain
nTPM: 96.0
Samples: 4

Max nTPM: 99.8
Min nTPM: 92.9
Sample A 95.0
Sample A 99.8
Sample A 92.9
Sample A 96.4

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