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BETA
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  • SPG21
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:46.7 nTPM
HPA Brain:52.7 nTPM
GTEx:46.7 nTPM
FANTOM5:55.9 Scaled Tags Per Million
Macaque:32.1 nTPM
Mouse:19.3 nTPM
Rat:24.1 nTPM
Pig:23.2 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 50
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 50
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 49.1
2411 Female, age 72, unknown 53.6
2019 Male, age 18, unknown 53.2
1870 Female, age 42, unknown 52.9
1833 Male, age 53, unknown 50.8
2666 Male, age 74, left hemisphere 50.4
1830 Male, age 51, unknown 49.4
2828 Female, age 72, unknown 47.5
1827 Male, age 72, unknown 47.4
2586 Male, age 75, left hemisphere 45.4
2219 Male, age 76, both hemispheres 40.2
Dorsal raphe nucleus
nTPM: 52.2
2016 Female, age 72, unknown 53.2
2298 Female, age 72, unknown 53.1
2750 Male, age 76, both hemispheres 52.9
2047 Male, age 72, unknown 52.5
1828 Male, age 53, unknown 49.2
Inferior colliculus
nTPM: 46.9
2097 Female, age 72, unknown 50.1
1890 Male, age 53, unknown 47.9
1848 Female, age 42, unknown 47.1
2849 Male, age 72, unknown 42.6
Median raphe nucleus
nTPM: 52.1
2220 Male, age 76, midline 52.1
Periaquaductal grey, anterior
nTPM: 44.5
2502 Female, age 75, unknown 45.7
1947 Male, age 18, unknown 44.6
1795 Male, age 51, unknown 43.2
Periaquaductal grey, dorsal
nTPM: 48.3
2464 Female, age 72, unknown 49.5
1840 Male, age 53, unknown 48.9
2850 Male, age 76, both hemispheres 47.5
1831 Male, age 72, unknown 47.3
Periaquaductal grey, lateral
nTPM: 46.4
2053 Male, age 18, unknown 47.8
2140 Male, age 76, both hemispheres 46.6
2272 Male, age 74, both hemispheres 44.9
Pretectal area
nTPM: 46.6
2273 Male, age 74, both hemispheres 51.6
2224 Female, age 72, unknown 50.5
1817 Female, age 42, unknown 50.1
2007 Male, age 72, unknown 48.3
2316 Male, age 76, right hemisphere 47.5
1815 Male, age 53, unknown 46.4
2667 Female, age 75, unknown 46.4
1816 Male, age 51, unknown 44.8
1944 Female, age 72, unknown 43.9
2825 Male, age 18, unknown 42.4
2407 Male, age 75, both hemispheres 41.0
Red nucleus
nTPM: 51.2
1821 Female, age 72, unknown 58.7
1904 Male, age 53, unknown 56.9
1954 Female, age 42, unknown 51.6
2503 Female, age 72, unknown 51.3
2227 Male, age 72, unknown 50.8
2823 Male, age 76, right hemisphere 50.8
2785 Male, age 18, unknown 50.5
1865 Male, age 51, unknown 50.4
2769 Male, age 72, unknown 49.9
2725 Female, age 75, unknown 49.8
2588 Male, age 74, left hemisphere 48.8
2584 Male, age 75, left hemisphere 45.6
Substantia nigra
nTPM: 52.7
2409 Female, age 72, unknown 59.6
1851 Male, age 51, unknown 58.1
2241 Male, age 72, unknown 54.4
1916 Female, age 42, unknown 53.6
2699 Male, age 18, unknown 53.1
2590 Female, age 75, unknown 50.8
2583 Male, age 75, right hemisphere 50.7
2665 Male, age 74, both hemispheres 49.3
1941 Male, age 53, unknown 49.0
1889 Female, age 72, unknown 48.0
Superior colliculus
nTPM: 46.3
1913 Female, age 42, unknown 51.9
1995 Male, age 72, unknown 51.0
2668 Female, age 75, unknown 48.0
1839 Male, age 51, unknown 46.7
2587 Male, age 74, left hemisphere 46.4
1895 Male, age 76, right hemisphere 45.7
2261 Male, age 18, unknown 45.2
2087 Female, age 72, unknown 44.2
1796 Male, age 53, unknown 42.9
2664 Male, age 75, both hemispheres 41.1
Ventral tegmental area
nTPM: 51.8
2021 Male, age 53, unknown 53.1
2410 Female, age 72, unknown 53.0
1915 Female, age 42, unknown 52.9
2223 Female, age 72, unknown 52.0
2218 Male, age 76, both hemispheres 49.9
1942 Male, age 51, unknown 49.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 46.7
Samples: 183

Max nTPM: 71.8
Min nTPM: 29.8
Std nTPM: 7.3
Median nTPM: 45.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 71.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 70.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 66.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 66.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 65.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 64.7
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 60.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 60.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 60.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 59.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 59.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 58.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 58.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 58.0
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 57.8
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 57.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 57.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 57.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 57.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 56.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 56.3
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 56.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 55.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 55.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 54.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 54.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 54.4
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 54.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 54.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 53.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 53.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 53.2
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 53.0
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 53.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 52.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 52.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 52.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 51.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 51.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 51.7
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 51.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 51.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 51.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 51.2
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 51.0
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 51.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.4
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 50.4
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 50.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 50.2
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 50.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 50.1
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 50.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 50.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 49.8
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 49.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 49.6
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 49.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 49.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 49.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 48.9
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 48.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 48.8
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 48.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 48.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 48.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 48.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 48.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 47.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 47.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 47.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 47.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 47.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 47.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 47.2
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 47.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 47.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 47.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 46.9
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 46.9
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 46.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 46.6
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 46.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 46.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 46.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 46.1
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 46.0
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 45.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 45.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 45.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.9
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 44.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 44.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 44.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 44.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 44.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 44.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.3
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 44.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 44.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 44.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 44.2
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 44.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 43.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 43.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 43.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 43.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 43.7
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 43.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 43.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 43.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 43.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 43.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 43.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 43.0
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 42.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 42.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 42.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 42.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 42.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 42.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 42.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 42.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 42.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 42.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 42.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 42.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 41.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 41.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 41.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 41.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 41.4
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 41.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 41.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 41.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 41.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 41.1
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 41.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 40.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 40.7
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 40.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 40.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 40.2
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 40.2
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 40.2
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 40.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 39.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 39.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 39.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 39.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 39.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 39.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 39.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 38.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 38.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 38.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 38.3
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 38.1
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 38.1
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 37.8
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 37.8
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 37.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 37.2
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 37.2
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 37.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 37.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 36.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 36.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 36.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 36.0
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 35.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 34.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 33.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 32.7
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 29.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

55.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 55.9
FF:10158-103A5 76 years, female 55.9

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 32.1
Samples: 1

Max nTPM: 32.1
Min nTPM: 32.1
Sample A 32.1
Midbrain
nTPM: 28.3
Samples: 1

Max nTPM: 28.3
Min nTPM: 28.3
Sample A 28.3
Superior colliculi
nTPM: 28.2
Samples: 1

Max nTPM: 28.2
Min nTPM: 28.2
Sample A 28.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 22.4
Samples: 3

Max nTPM: 25.6
Min nTPM: 18.9
Sample A Female 25.6
Sample B Female 22.8
Sample C Male 18.9
Midbrain
nTPM: 18.8
Samples: 3

Max nTPM: 20.5
Min nTPM: 15.9
Sample B Female 20.1
Sample C Male 20.5
Sample D Male 15.9
Periaqueductal gray
nTPM: 16.8
Samples: 3

Max nTPM: 18.3
Min nTPM: 15.4
Sample B Female 18.3
Sample C Male 16.8
Sample D Male 15.4
Superior colliculi
nTPM: 23.2
Samples: 4

Max nTPM: 29.2
Min nTPM: 19.1
Sample A Female 23.9
Sample B Female 29.2
Sample C Male 20.5
Sample D Male 19.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

19.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 19.3
Samples: 4

Max nTPM: 20.1
Min nTPM: 18.3
Sample A 19.7
Sample B 20.1
Sample C 19.0
Sample D 18.3

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.1
Rat sample Sample description nTPM
Midbrain
nTPM: 24.1
Samples: 4

Max nTPM: 25.5
Min nTPM: 22.7
Sample A 25.5
Sample A 23.8
Sample A 24.5
Sample A 22.7

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