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BETA
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:27.8 nTPM
HPA Brain:126.2 nTPM
GTEx:27.8 nTPM
FANTOM5:90.7 Scaled Tags Per Million
Macaque:31.3 nTPM
Mouse:14.9 nTPM
Rat:41.3 nTPM
Pig:33.3 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 20
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 190
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 104.0
1830 Male, age 51, unknown 136.6
1870 Female, age 42, unknown 121.5
2411 Female, age 72, unknown 121.4
1833 Male, age 53, unknown 120.2
2019 Male, age 18, unknown 115.9
2586 Male, age 75, left hemisphere 99.4
2828 Female, age 72, unknown 86.4
2666 Male, age 74, left hemisphere 83.0
1827 Male, age 72, unknown 80.9
2219 Male, age 76, both hemispheres 74.3
Dorsal raphe nucleus
nTPM: 80.9
2750 Male, age 76, both hemispheres 129.0
1828 Male, age 53, unknown 83.2
2016 Female, age 72, unknown 78.4
2047 Male, age 72, unknown 63.1
2298 Female, age 72, unknown 50.6
Inferior colliculus
nTPM: 70.5
1890 Male, age 53, unknown 79.7
2849 Male, age 72, unknown 73.3
1848 Female, age 42, unknown 73.2
2097 Female, age 72, unknown 55.8
Median raphe nucleus
nTPM: 91.4
2220 Male, age 76, midline 91.4
Periaquaductal grey, anterior
nTPM: 68.9
2502 Female, age 75, unknown 81.7
1947 Male, age 18, unknown 70.9
1795 Male, age 51, unknown 54.2
Periaquaductal grey, dorsal
nTPM: 61.9
2464 Female, age 72, unknown 79.4
2850 Male, age 76, both hemispheres 64.9
1831 Male, age 72, unknown 58.2
1840 Male, age 53, unknown 45.0
Periaquaductal grey, lateral
nTPM: 70.5
2140 Male, age 76, both hemispheres 73.4
2053 Male, age 18, unknown 71.7
2272 Male, age 74, both hemispheres 66.5
Pretectal area
nTPM: 68.5
2407 Male, age 75, both hemispheres 97.9
2316 Male, age 76, right hemisphere 85.6
1815 Male, age 53, unknown 80.9
2825 Male, age 18, unknown 78.5
2667 Female, age 75, unknown 68.7
2224 Female, age 72, unknown 64.3
2273 Male, age 74, both hemispheres 64.3
1817 Female, age 42, unknown 63.3
2007 Male, age 72, unknown 62.9
1944 Female, age 72, unknown 45.8
1816 Male, age 51, unknown 41.3
Red nucleus
nTPM: 126.2
1865 Male, age 51, unknown 164.0
1904 Male, age 53, unknown 145.2
2823 Male, age 76, right hemisphere 140.2
2769 Male, age 72, unknown 139.1
1821 Female, age 72, unknown 132.0
2227 Male, age 72, unknown 131.8
2785 Male, age 18, unknown 131.3
1954 Female, age 42, unknown 118.1
2503 Female, age 72, unknown 114.9
2588 Male, age 74, left hemisphere 111.7
2584 Male, age 75, left hemisphere 104.9
2725 Female, age 75, unknown 81.4
Substantia nigra
nTPM: 84.9
2583 Male, age 75, right hemisphere 114.7
1851 Male, age 51, unknown 96.4
2590 Female, age 75, unknown 95.9
2699 Male, age 18, unknown 89.8
2409 Female, age 72, unknown 87.5
2241 Male, age 72, unknown 80.1
1889 Female, age 72, unknown 75.2
1916 Female, age 42, unknown 73.1
1941 Male, age 53, unknown 70.3
2665 Male, age 74, both hemispheres 66.3
Superior colliculus
nTPM: 82.0
1913 Female, age 42, unknown 119.0
1995 Male, age 72, unknown 112.8
1895 Male, age 76, right hemisphere 90.0
2587 Male, age 74, left hemisphere 86.1
2668 Female, age 75, unknown 85.6
1839 Male, age 51, unknown 82.7
2664 Male, age 75, both hemispheres 73.4
1796 Male, age 53, unknown 65.1
2087 Female, age 72, unknown 56.3
2261 Male, age 18, unknown 49.1
Ventral tegmental area
nTPM: 94.2
2223 Female, age 72, unknown 119.3
2410 Female, age 72, unknown 111.6
1942 Male, age 51, unknown 88.0
2021 Male, age 53, unknown 87.9
2218 Male, age 76, both hemispheres 81.0
1915 Female, age 42, unknown 77.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 27.8
Samples: 183

Max nTPM: 65.5
Min nTPM: 6.8
Std nTPM: 11.6
Median nTPM: 24.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 65.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 65.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 65.0
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 62.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 62.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 60.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 53.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 52.0
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 51.8
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 51.0
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 48.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 46.5
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 46.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 45.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 44.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 44.0
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 43.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 43.5
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 41.9
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 41.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 41.3
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 41.3
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 41.2
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 40.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 40.4
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 39.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 39.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 39.5
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 39.4
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 39.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 38.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 38.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 36.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 36.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 36.2
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 36.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 35.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 35.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 35.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 35.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 35.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 35.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 34.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 34.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 34.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 34.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 33.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 32.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 32.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 32.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 32.1
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 32.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 31.9
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 31.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 31.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 31.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 30.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 30.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 30.4
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 30.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 30.0
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 29.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 29.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 29.0
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 29.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 28.9
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 28.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 28.4
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 28.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 27.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 27.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 27.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 27.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 27.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 27.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 27.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.2
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 27.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 26.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 26.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 26.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 26.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 25.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 25.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 25.6
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 25.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 25.0
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 24.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 24.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 24.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 24.5
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 24.3
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 24.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 24.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 24.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 24.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 23.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 23.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 23.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 23.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 23.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 23.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 23.4
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 23.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 23.1
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 22.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 22.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 22.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 22.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 22.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 22.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 22.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 22.2
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 21.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 21.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 21.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 21.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 21.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 21.3
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 21.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 21.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 21.0
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 20.7
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 20.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 20.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 20.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 20.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 20.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 20.0
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 19.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 19.8
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 19.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 19.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 19.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 19.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 19.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 19.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 19.1
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 19.1
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 19.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 18.9
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 18.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 18.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 18.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 18.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 18.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 17.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 17.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 17.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 17.7
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 17.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 17.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 17.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 17.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 17.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 17.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 17.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 17.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 17.2
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 17.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 16.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 16.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 16.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 16.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 16.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 15.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 14.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 14.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 14.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 14.5
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 14.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 14.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 14.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 13.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 13.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 13.6
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 13.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 12.9
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 12.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 8.9
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 6.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

90.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 90.7
FF:10158-103A5 76 years, female 90.7

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

31.3
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 31.3
Samples: 1

Max nTPM: 31.3
Min nTPM: 31.3
Sample A 31.3
Midbrain
nTPM: 18.8
Samples: 1

Max nTPM: 18.8
Min nTPM: 18.8
Sample A 18.8
Superior colliculi
nTPM: 26.2
Samples: 1

Max nTPM: 26.2
Min nTPM: 26.2
Sample A 26.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

33.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 33.3
Samples: 3

Max nTPM: 37.0
Min nTPM: 28.0
Sample A Female 37.0
Sample B Female 28.0
Sample C Male 34.9
Midbrain
nTPM: 28.6
Samples: 3

Max nTPM: 38.9
Min nTPM: 22.6
Sample B Female 38.9
Sample C Male 22.6
Sample D Male 24.2
Periaqueductal gray
nTPM: 31.0
Samples: 3

Max nTPM: 35.8
Min nTPM: 28.1
Sample B Female 35.8
Sample C Male 28.1
Sample D Male 29.1
Superior colliculi
nTPM: 27.5
Samples: 4

Max nTPM: 34.6
Min nTPM: 15.4
Sample A Female 31.3
Sample B Female 15.4
Sample C Male 28.8
Sample D Male 34.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

14.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 14.9
Samples: 4

Max nTPM: 15.6
Min nTPM: 14.5
Sample A 14.9
Sample B 15.6
Sample C 14.6
Sample D 14.5

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.3
Rat sample Sample description nTPM
Midbrain
nTPM: 41.3
Samples: 4

Max nTPM: 43.6
Min nTPM: 39.9
Sample A 39.9
Sample A 43.6
Sample A 39.9
Sample A 41.7

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