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BETA
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  • MARCHF2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:90.4 nTPM
HPA Brain:121.1 nTPM
GTEx:90.4 nTPM
FANTOM5:42.5 Scaled Tags Per Million
Macaque:45.4 nTPM
Mouse:82.8 nTPM
Rat:79.2 nTPM
Pig:53.5 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 70
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 60
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

121.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 116.9
2586 Male, age 75, left hemisphere 188.2
2019 Male, age 18, unknown 151.0
2828 Female, age 72, unknown 112.5
2666 Male, age 74, left hemisphere 108.5
2411 Female, age 72, unknown 107.7
1830 Male, age 51, unknown 103.8
1827 Male, age 72, unknown 103.5
1833 Male, age 53, unknown 101.6
1870 Female, age 42, unknown 100.1
2219 Male, age 76, both hemispheres 91.7
Dorsal raphe nucleus
nTPM: 102.9
1828 Male, age 53, unknown 118.4
2047 Male, age 72, unknown 109.5
2750 Male, age 76, both hemispheres 103.5
2016 Female, age 72, unknown 98.4
2298 Female, age 72, unknown 84.8
Inferior colliculus
nTPM: 100.9
1848 Female, age 42, unknown 112.2
1890 Male, age 53, unknown 101.6
2849 Male, age 72, unknown 100.2
2097 Female, age 72, unknown 89.6
Median raphe nucleus
nTPM: 98.1
2220 Male, age 76, midline 98.1
Periaquaductal grey, anterior
nTPM: 105.2
2502 Female, age 75, unknown 117.3
1795 Male, age 51, unknown 102.5
1947 Male, age 18, unknown 95.7
Periaquaductal grey, dorsal
nTPM: 81.1
2464 Female, age 72, unknown 91.5
1840 Male, age 53, unknown 89.9
2850 Male, age 76, both hemispheres 73.8
1831 Male, age 72, unknown 69.2
Periaquaductal grey, lateral
nTPM: 76.9
2140 Male, age 76, both hemispheres 79.5
2053 Male, age 18, unknown 76.4
2272 Male, age 74, both hemispheres 74.8
Pretectal area
nTPM: 100.7
2007 Male, age 72, unknown 144.2
1817 Female, age 42, unknown 131.4
1816 Male, age 51, unknown 114.9
1944 Female, age 72, unknown 106.5
2407 Male, age 75, both hemispheres 105.1
1815 Male, age 53, unknown 101.3
2316 Male, age 76, right hemisphere 87.1
2667 Female, age 75, unknown 85.8
2825 Male, age 18, unknown 81.1
2224 Female, age 72, unknown 78.4
2273 Male, age 74, both hemispheres 72.4
Red nucleus
nTPM: 120.9
2785 Male, age 18, unknown 148.1
2584 Male, age 75, left hemisphere 135.8
2588 Male, age 74, left hemisphere 135.0
2227 Male, age 72, unknown 130.5
2769 Male, age 72, unknown 127.8
2503 Female, age 72, unknown 119.9
1821 Female, age 72, unknown 114.9
1954 Female, age 42, unknown 112.6
1904 Male, age 53, unknown 112.0
1865 Male, age 51, unknown 110.9
2823 Male, age 76, right hemisphere 105.3
2725 Female, age 75, unknown 97.9
Substantia nigra
nTPM: 121.1
2665 Male, age 74, both hemispheres 151.3
1916 Female, age 42, unknown 143.3
1851 Male, age 51, unknown 133.3
2583 Male, age 75, right hemisphere 125.4
2590 Female, age 75, unknown 125.0
1941 Male, age 53, unknown 121.3
1889 Female, age 72, unknown 114.4
2699 Male, age 18, unknown 101.6
2241 Male, age 72, unknown 98.7
2409 Female, age 72, unknown 97.1
Superior colliculus
nTPM: 103.7
2664 Male, age 75, both hemispheres 141.0
2668 Female, age 75, unknown 123.7
2087 Female, age 72, unknown 105.8
1796 Male, age 53, unknown 102.8
1839 Male, age 51, unknown 101.6
2261 Male, age 18, unknown 99.2
2587 Male, age 74, left hemisphere 96.1
1895 Male, age 76, right hemisphere 95.7
1995 Male, age 72, unknown 88.5
1913 Female, age 42, unknown 83.0
Ventral tegmental area
nTPM: 107.9
1915 Female, age 42, unknown 117.9
2410 Female, age 72, unknown 116.7
2223 Female, age 72, unknown 110.7
2218 Male, age 76, both hemispheres 104.8
1942 Male, age 51, unknown 101.9
2021 Male, age 53, unknown 95.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

90.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 90.4
Samples: 183

Max nTPM: 159.0
Min nTPM: 38.5
Std nTPM: 20.6
Median nTPM: 89.8
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 159.0
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 145.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 143.5
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 143.0
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 137.4
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 134.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 132.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 128.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 128.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 126.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 125.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 122.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 119.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 119.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 118.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 118.4
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 117.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 115.8
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 115.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 115.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 114.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 114.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 113.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 113.6
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 113.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 112.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 112.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 111.7
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 110.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 109.8
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 108.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 107.8
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 106.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 106.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 106.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 106.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 105.7
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 105.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.4
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 104.8
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 104.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 104.1
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 104.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 103.8
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 103.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 103.3
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 102.9
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 102.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 102.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 101.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 101.2
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 100.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 100.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 99.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 99.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 99.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 99.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 99.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 98.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 98.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 98.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 98.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 98.2
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 97.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 97.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 97.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 97.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 97.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 96.9
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 96.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 96.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 96.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 96.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 96.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 95.6
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 95.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 95.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 95.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 94.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 94.0
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 93.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 93.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 93.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 93.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 93.0
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 92.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 92.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 91.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 91.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 91.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 90.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 89.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 89.6
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 89.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 88.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 88.5
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 88.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 88.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 86.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 86.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 85.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 85.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 85.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 85.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 85.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 84.5
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 84.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 83.6
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 83.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 83.1
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 82.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 82.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 81.5
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 80.8
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 80.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 80.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 80.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 79.8
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 79.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 79.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 79.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 78.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 78.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 78.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 77.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 77.7
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 77.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 77.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 77.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 77.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 77.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 77.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 76.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 76.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 76.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 76.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 75.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 75.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 75.0
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 74.9
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 74.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 74.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 74.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 73.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 73.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 73.3
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 73.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 73.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 73.1
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 72.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 72.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 72.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 72.5
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 72.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 72.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 70.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 70.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 69.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 69.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 68.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 68.6
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 68.6
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 68.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 66.8
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 65.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 65.0
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 64.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 63.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 63.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 62.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 61.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 59.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 57.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 56.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 52.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 49.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 48.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 46.1
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 45.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 38.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

42.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 42.5
FF:10158-103A5 76 years, female 42.5

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.4
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 34.7
Samples: 1

Max nTPM: 34.7
Min nTPM: 34.7
Sample A 34.7
Midbrain
nTPM: 29.7
Samples: 1

Max nTPM: 29.7
Min nTPM: 29.7
Sample A 29.7
Superior colliculi
nTPM: 45.4
Samples: 1

Max nTPM: 45.4
Min nTPM: 45.4
Sample A 45.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

53.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 43.5
Samples: 3

Max nTPM: 56.9
Min nTPM: 32.1
Sample A Female 56.9
Sample B Female 32.1
Sample C Male 41.6
Midbrain
nTPM: 44.0
Samples: 3

Max nTPM: 58.2
Min nTPM: 36.1
Sample B Female 37.8
Sample C Male 58.2
Sample D Male 36.1
Periaqueductal gray
nTPM: 31.5
Samples: 3

Max nTPM: 35.9
Min nTPM: 24.6
Sample B Female 35.9
Sample C Male 34.0
Sample D Male 24.6
Superior colliculi
nTPM: 53.5
Samples: 4

Max nTPM: 62.2
Min nTPM: 44.8
Sample A Female 59.5
Sample B Female 44.8
Sample C Male 62.2
Sample D Male 47.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

82.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 82.8
Samples: 4

Max nTPM: 89.5
Min nTPM: 78.6
Sample A 84.0
Sample B 89.5
Sample C 78.6
Sample D 79.0

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

79.2
Rat sample Sample description nTPM
Midbrain
nTPM: 79.3
Samples: 4

Max nTPM: 83.7
Min nTPM: 75.8
Sample A 77.7
Sample A 83.7
Sample A 79.8
Sample A 75.8

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