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  • GPI
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:84.6 nTPM
HPA Brain:190.6 nTPM
GTEx:84.6 nTPM
FANTOM5:145.3 Scaled Tags Per Million
Macaque:11.1 nTPM
Mouse:359.5 nTPM
Rat:315.2 nTPM
Pig:334.1 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 280
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 220
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

190.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 153.0
2586 Male, age 75, left hemisphere 200.2
1827 Male, age 72, unknown 178.8
2019 Male, age 18, unknown 175.9
2828 Female, age 72, unknown 166.8
2219 Male, age 76, both hemispheres 165.6
2666 Male, age 74, left hemisphere 147.7
2411 Female, age 72, unknown 138.8
1870 Female, age 42, unknown 127.4
1833 Male, age 53, unknown 120.9
1830 Male, age 51, unknown 107.8
Dorsal raphe nucleus
nTPM: 156.3
2298 Female, age 72, unknown 202.7
2047 Male, age 72, unknown 183.7
1828 Male, age 53, unknown 154.9
2750 Male, age 76, both hemispheres 138.4
2016 Female, age 72, unknown 101.7
Inferior colliculus
nTPM: 154.0
2097 Female, age 72, unknown 181.7
1890 Male, age 53, unknown 153.4
1848 Female, age 42, unknown 149.3
2849 Male, age 72, unknown 131.5
Median raphe nucleus
nTPM: 175.7
2220 Male, age 76, midline 175.7
Periaquaductal grey, anterior
nTPM: 155.0
1795 Male, age 51, unknown 169.4
1947 Male, age 18, unknown 165.9
2502 Female, age 75, unknown 129.7
Periaquaductal grey, dorsal
nTPM: 126.6
1840 Male, age 53, unknown 145.9
1831 Male, age 72, unknown 134.5
2850 Male, age 76, both hemispheres 113.6
2464 Female, age 72, unknown 112.3
Periaquaductal grey, lateral
nTPM: 119.5
2272 Male, age 74, both hemispheres 136.2
2053 Male, age 18, unknown 119.7
2140 Male, age 76, both hemispheres 102.5
Pretectal area
nTPM: 184.0
1817 Female, age 42, unknown 272.1
1944 Female, age 72, unknown 267.1
1816 Male, age 51, unknown 263.6
2007 Male, age 72, unknown 263.2
1815 Male, age 53, unknown 199.7
2667 Female, age 75, unknown 182.5
2224 Female, age 72, unknown 141.7
2273 Male, age 74, both hemispheres 121.7
2825 Male, age 18, unknown 116.5
2407 Male, age 75, both hemispheres 114.2
2316 Male, age 76, right hemisphere 81.4
Red nucleus
nTPM: 129.7
2785 Male, age 18, unknown 159.7
1821 Female, age 72, unknown 158.5
2725 Female, age 75, unknown 141.7
2584 Male, age 75, left hemisphere 137.8
2588 Male, age 74, left hemisphere 135.5
1954 Female, age 42, unknown 127.8
1865 Male, age 51, unknown 119.3
1904 Male, age 53, unknown 118.0
2503 Female, age 72, unknown 115.4
2769 Male, age 72, unknown 115.3
2227 Male, age 72, unknown 114.9
2823 Male, age 76, right hemisphere 112.1
Substantia nigra
nTPM: 190.6
1916 Female, age 42, unknown 293.2
1889 Female, age 72, unknown 250.1
1851 Male, age 51, unknown 222.2
1941 Male, age 53, unknown 215.7
2665 Male, age 74, both hemispheres 192.2
2699 Male, age 18, unknown 152.0
2583 Male, age 75, right hemisphere 150.7
2241 Male, age 72, unknown 148.0
2409 Female, age 72, unknown 144.2
2590 Female, age 75, unknown 138.0
Superior colliculus
nTPM: 155.4
2087 Female, age 72, unknown 227.0
2668 Female, age 75, unknown 203.8
2261 Male, age 18, unknown 170.5
1796 Male, age 53, unknown 170.2
1895 Male, age 76, right hemisphere 148.3
2664 Male, age 75, both hemispheres 136.0
1913 Female, age 42, unknown 131.1
1839 Male, age 51, unknown 127.0
2587 Male, age 74, left hemisphere 124.2
1995 Male, age 72, unknown 115.6
Ventral tegmental area
nTPM: 163.5
2410 Female, age 72, unknown 209.0
1915 Female, age 42, unknown 197.1
2218 Male, age 76, both hemispheres 189.8
1942 Male, age 51, unknown 139.4
2223 Female, age 72, unknown 127.3
2021 Male, age 53, unknown 118.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

84.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 84.6
Samples: 183

Max nTPM: 274.7
Min nTPM: 30.5
Std nTPM: 42.9
Median nTPM: 71.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 274.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 241.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 225.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 218.8
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 209.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 190.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 186.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 179.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 164.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 163.8
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 161.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 161.0
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 158.5
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 153.9
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 152.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 150.4
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 150.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 145.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 145.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 143.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 143.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 142.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 140.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 136.7
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 134.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 130.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 126.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 126.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 125.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 124.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 122.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 122.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 120.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 120.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 116.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 115.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 114.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 113.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 112.6
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 112.5
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 111.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 110.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 110.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 109.3
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 107.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 102.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 100.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 95.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 94.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 94.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 94.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 93.4
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 90.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 89.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 89.0
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 88.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 87.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 85.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 84.9
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 84.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 84.3
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 84.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 83.3
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 83.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 82.7
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 82.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 82.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 81.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 81.4
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 80.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 80.4
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 79.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 79.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 78.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 78.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 77.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 77.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 77.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 75.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 75.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 75.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 74.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 74.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 74.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 73.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 72.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 71.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 71.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.0
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 71.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 70.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 70.5
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 70.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 70.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 69.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 69.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 69.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 68.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 68.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 68.5
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 68.0
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 67.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 67.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 67.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 67.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 67.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 66.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 66.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 66.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 65.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 65.2
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 65.0
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 65.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 64.6
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 64.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 64.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 64.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 62.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 62.7
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 62.7
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 61.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 60.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 60.9
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 60.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 60.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 59.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 59.5
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 59.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 58.7
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 58.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 56.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 54.8
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 54.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 54.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 54.0
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 54.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 53.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 53.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 53.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 52.8
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 52.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 52.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 52.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 52.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 51.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 51.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.7
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 50.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 50.0
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 49.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 48.6
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 48.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 47.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 46.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 46.1
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 44.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 44.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 43.7
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 43.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 42.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 42.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 41.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 41.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 40.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 39.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 39.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 39.0
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 38.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 37.5
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 35.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 35.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 34.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 32.2
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 30.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

145.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 145.3
FF:10158-103A5 76 years, female 145.3

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 244.1
Samples: 1

Max nTPM: 244.1
Min nTPM: 244.1
Sample A 244.1
Midbrain
nTPM: 213.1
Samples: 1

Max nTPM: 213.1
Min nTPM: 213.1
Sample A 213.1
Superior colliculi
nTPM: 285.3
Samples: 1

Max nTPM: 285.3
Min nTPM: 285.3
Sample A 285.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

334.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 334.1
Samples: 3

Max nTPM: 404.3
Min nTPM: 220.1
Sample A Female 404.3
Sample B Female 220.1
Sample C Male 378.0
Midbrain
nTPM: 321.1
Samples: 3

Max nTPM: 406.7
Min nTPM: 235.2
Sample B Female 235.2
Sample C Male 406.7
Sample D Male 321.3
Periaqueductal gray
nTPM: 219.4
Samples: 3

Max nTPM: 258.1
Min nTPM: 187.4
Sample B Female 212.6
Sample C Male 258.1
Sample D Male 187.4
Superior colliculi
nTPM: 327.3
Samples: 4

Max nTPM: 390.8
Min nTPM: 247.8
Sample A Female 351.5
Sample B Female 247.8
Sample C Male 390.8
Sample D Male 319.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

359.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 359.5
Samples: 4

Max nTPM: 371.5
Min nTPM: 334.8
Sample A 362.0
Sample B 334.8
Sample C 369.5
Sample D 371.5

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

315.2
Rat sample Sample description nTPM
Midbrain
nTPM: 315.3
Samples: 4

Max nTPM: 327.4
Min nTPM: 294.4
Sample A 316.6
Sample A 327.4
Sample A 322.6
Sample A 294.4

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