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BETA
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  • BRAIN

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  • PLD3
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:228.3 nTPM
HPA Brain:398.8 nTPM
GTEx:228.3 nTPM
FANTOM5:118.8 Scaled Tags Per Million
Macaque:236.6 nTPM
Mouse:205.5 nTPM
Rat:164.7 nTPM
Pig:522.1 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 310
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 240
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

398.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 295.0
2666 Male, age 74, left hemisphere 432.6
2219 Male, age 76, both hemispheres 375.5
2586 Male, age 75, left hemisphere 318.8
1827 Male, age 72, unknown 317.0
1870 Female, age 42, unknown 285.9
2411 Female, age 72, unknown 281.3
1833 Male, age 53, unknown 255.0
2828 Female, age 72, unknown 244.1
2019 Male, age 18, unknown 221.8
1830 Male, age 51, unknown 217.9
Dorsal raphe nucleus
nTPM: 295.0
2298 Female, age 72, unknown 345.9
2047 Male, age 72, unknown 341.3
1828 Male, age 53, unknown 296.3
2750 Male, age 76, both hemispheres 271.3
2016 Female, age 72, unknown 220.1
Inferior colliculus
nTPM: 250.8
2849 Male, age 72, unknown 275.9
1848 Female, age 42, unknown 253.6
2097 Female, age 72, unknown 241.4
1890 Male, age 53, unknown 232.2
Median raphe nucleus
nTPM: 383.9
2220 Male, age 76, midline 383.9
Periaquaductal grey, anterior
nTPM: 295.2
1947 Male, age 18, unknown 318.9
1795 Male, age 51, unknown 318.5
2502 Female, age 75, unknown 248.3
Periaquaductal grey, dorsal
nTPM: 243.1
1840 Male, age 53, unknown 305.0
2850 Male, age 76, both hemispheres 244.3
1831 Male, age 72, unknown 235.4
2464 Female, age 72, unknown 187.5
Periaquaductal grey, lateral
nTPM: 214.6
2053 Male, age 18, unknown 226.1
2272 Male, age 74, both hemispheres 210.9
2140 Male, age 76, both hemispheres 206.9
Pretectal area
nTPM: 287.5
2007 Male, age 72, unknown 369.1
1816 Male, age 51, unknown 343.0
1944 Female, age 72, unknown 331.5
1817 Female, age 42, unknown 331.3
2224 Female, age 72, unknown 318.9
1815 Male, age 53, unknown 303.0
2667 Female, age 75, unknown 298.2
2825 Male, age 18, unknown 280.2
2407 Male, age 75, both hemispheres 238.0
2316 Male, age 76, right hemisphere 182.4
2273 Male, age 74, both hemispheres 166.7
Red nucleus
nTPM: 213.7
2584 Male, age 75, left hemisphere 370.3
1821 Female, age 72, unknown 232.3
2785 Male, age 18, unknown 231.8
2725 Female, age 75, unknown 231.2
2588 Male, age 74, left hemisphere 218.2
2769 Male, age 72, unknown 194.9
1954 Female, age 42, unknown 188.9
2227 Male, age 72, unknown 188.5
1904 Male, age 53, unknown 183.5
2503 Female, age 72, unknown 179.0
2823 Male, age 76, right hemisphere 177.3
1865 Male, age 51, unknown 169.0
Substantia nigra
nTPM: 398.8
1916 Female, age 42, unknown 666.3
1851 Male, age 51, unknown 482.7
2665 Male, age 74, both hemispheres 446.6
1941 Male, age 53, unknown 410.1
2241 Male, age 72, unknown 377.7
2699 Male, age 18, unknown 375.7
1889 Female, age 72, unknown 353.6
2409 Female, age 72, unknown 328.9
2583 Male, age 75, right hemisphere 312.7
2590 Female, age 75, unknown 233.4
Superior colliculus
nTPM: 261.9
2668 Female, age 75, unknown 419.0
1796 Male, age 53, unknown 320.7
2261 Male, age 18, unknown 265.4
2664 Male, age 75, both hemispheres 265.2
2087 Female, age 72, unknown 256.5
1839 Male, age 51, unknown 256.1
1895 Male, age 76, right hemisphere 248.3
2587 Male, age 74, left hemisphere 233.5
1913 Female, age 42, unknown 188.3
1995 Male, age 72, unknown 166.5
Ventral tegmental area
nTPM: 384.6
1915 Female, age 42, unknown 486.3
2218 Male, age 76, both hemispheres 479.8
2410 Female, age 72, unknown 403.4
1942 Male, age 51, unknown 364.7
2223 Female, age 72, unknown 297.5
2021 Male, age 53, unknown 275.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

228.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 228.3
Samples: 183

Max nTPM: 825.4
Min nTPM: 73.4
Std nTPM: 148.1
Median nTPM: 179.6
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 825.4
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 727.8
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 695.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 678.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 631.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 626.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 618.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 584.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 553.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 539.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 538.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 531.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 525.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 493.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 490.6
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 475.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 459.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 437.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 428.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 425.4
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 400.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 393.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 392.1
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 390.6
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 388.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 385.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 385.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 380.6
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 373.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 354.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 347.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 347.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 342.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 341.1
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 331.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 325.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 324.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 316.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 302.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 296.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 296.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 292.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 290.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 290.0
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 289.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 286.9
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 282.4
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 281.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 277.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 275.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 270.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 269.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 268.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 267.8
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 264.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 263.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 259.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 258.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 256.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 253.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 253.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 250.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 249.6
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 249.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 245.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 240.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 239.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 231.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 229.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 229.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 228.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 228.5
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 228.0
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 222.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 218.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 218.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 214.1
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 211.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 200.2
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 199.9
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 199.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 195.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 195.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 193.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 192.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 189.5
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 189.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 188.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 184.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 184.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 180.6
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 179.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 179.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 177.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 172.2
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 172.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 171.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 168.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 164.3
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 161.7
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 161.6
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 160.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 159.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 157.6
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 157.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 156.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 154.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 153.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 152.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 151.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 147.9
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 145.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 145.5
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 144.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 143.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 141.8
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 141.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 139.7
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 139.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 138.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 136.4
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 136.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 134.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 134.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 129.9
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 129.8
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 129.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 129.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 127.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 126.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 125.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 125.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 122.8
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 122.6
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 122.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 122.0
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 120.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 120.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 118.1
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 117.9
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 117.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 116.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 116.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 116.2
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 114.8
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 113.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 112.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 111.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 111.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 108.9
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 108.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 108.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 106.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 104.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 104.2
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 100.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 98.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 97.5
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 96.7
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 95.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 93.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 92.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 92.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 89.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 89.7
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 89.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 89.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 88.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 87.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 87.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 87.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 86.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 85.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 84.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 84.4
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 83.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 83.5
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 83.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 82.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 79.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 75.9
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 74.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 73.4
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

118.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 118.8
FF:10158-103A5 76 years, female 118.8

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

236.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 148.5
Samples: 1

Max nTPM: 148.5
Min nTPM: 148.5
Sample A 148.5
Midbrain
nTPM: 190.3
Samples: 1

Max nTPM: 190.3
Min nTPM: 190.3
Sample A 190.3
Superior colliculi
nTPM: 236.6
Samples: 1

Max nTPM: 236.6
Min nTPM: 236.6
Sample A 236.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

522.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 522.0
Samples: 3

Max nTPM: 644.7
Min nTPM: 320.6
Sample A Female 600.6
Sample B Female 320.6
Sample C Male 644.7
Midbrain
nTPM: 522.1
Samples: 3

Max nTPM: 631.7
Min nTPM: 333.7
Sample B Female 333.7
Sample C Male 631.7
Sample D Male 600.8
Periaqueductal gray
nTPM: 391.0
Samples: 3

Max nTPM: 530.2
Min nTPM: 309.2
Sample B Female 309.2
Sample C Male 530.2
Sample D Male 333.6
Superior colliculi
nTPM: 473.0
Samples: 4

Max nTPM: 580.7
Min nTPM: 272.3
Sample A Female 580.7
Sample B Female 272.3
Sample C Male 495.6
Sample D Male 543.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

205.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 205.5
Samples: 4

Max nTPM: 222.4
Min nTPM: 187.8
Sample A 187.8
Sample B 222.4
Sample C 211.7
Sample D 200.1

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

164.7
Rat sample Sample description nTPM
Midbrain
nTPM: 164.7
Samples: 4

Max nTPM: 179.6
Min nTPM: 149.7
Sample A 163.8
Sample A 179.6
Sample A 165.8
Sample A 149.7

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