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BETA
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  • MAP1B
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:93.8 nTPM
HPA Brain:1058.0 nTPM
GTEx:93.8 nTPM
FANTOM5:358.6 Scaled Tags Per Million
Macaque:562.8 nTPM
Mouse:284.0 nTPM
Rat:347.8 nTPM
Pig:501.4 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 1880
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 670
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1058.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 794.6
2666 Male, age 74, left hemisphere 1235.5
2019 Male, age 18, unknown 1087.9
2586 Male, age 75, left hemisphere 897.7
1827 Male, age 72, unknown 828.7
2411 Female, age 72, unknown 773.9
2828 Female, age 72, unknown 749.1
2219 Male, age 76, both hemispheres 653.3
1870 Female, age 42, unknown 600.0
1830 Male, age 51, unknown 574.0
1833 Male, age 53, unknown 546.0
Dorsal raphe nucleus
nTPM: 838.2
2298 Female, age 72, unknown 1003.7
2047 Male, age 72, unknown 916.7
2750 Male, age 76, both hemispheres 892.1
1828 Male, age 53, unknown 888.7
2016 Female, age 72, unknown 489.8
Inferior colliculus
nTPM: 532.2
2097 Female, age 72, unknown 577.2
1890 Male, age 53, unknown 547.9
1848 Female, age 42, unknown 532.8
2849 Male, age 72, unknown 471.0
Median raphe nucleus
nTPM: 1058.0
2220 Male, age 76, midline 1058.0
Periaquaductal grey, anterior
nTPM: 761.4
1795 Male, age 51, unknown 860.8
2502 Female, age 75, unknown 747.2
1947 Male, age 18, unknown 676.1
Periaquaductal grey, dorsal
nTPM: 547.5
1831 Male, age 72, unknown 643.1
2850 Male, age 76, both hemispheres 550.0
2464 Female, age 72, unknown 509.8
1840 Male, age 53, unknown 487.0
Periaquaductal grey, lateral
nTPM: 510.1
2272 Male, age 74, both hemispheres 597.5
2053 Male, age 18, unknown 492.7
2140 Male, age 76, both hemispheres 440.0
Pretectal area
nTPM: 863.1
1816 Male, age 51, unknown 1369.6
1817 Female, age 42, unknown 1209.6
1944 Female, age 72, unknown 1207.0
2007 Male, age 72, unknown 1203.6
1815 Male, age 53, unknown 971.4
2667 Female, age 75, unknown 701.7
2407 Male, age 75, both hemispheres 654.2
2273 Male, age 74, both hemispheres 653.0
2224 Female, age 72, unknown 646.1
2825 Male, age 18, unknown 507.6
2316 Male, age 76, right hemisphere 370.6
Red nucleus
nTPM: 671.1
2785 Male, age 18, unknown 1044.3
2584 Male, age 75, left hemisphere 834.1
1821 Female, age 72, unknown 805.2
2588 Male, age 74, left hemisphere 664.4
2503 Female, age 72, unknown 652.6
1865 Male, age 51, unknown 641.4
1954 Female, age 42, unknown 618.8
2725 Female, age 75, unknown 579.6
1904 Male, age 53, unknown 579.2
2227 Male, age 72, unknown 558.6
2769 Male, age 72, unknown 549.9
2823 Male, age 76, right hemisphere 525.5
Substantia nigra
nTPM: 892.5
1941 Male, age 53, unknown 1244.6
1916 Female, age 42, unknown 1108.1
1889 Female, age 72, unknown 1101.7
2583 Male, age 75, right hemisphere 910.8
1851 Male, age 51, unknown 883.0
2241 Male, age 72, unknown 820.5
2665 Male, age 74, both hemispheres 795.5
2409 Female, age 72, unknown 733.8
2590 Female, age 75, unknown 698.6
2699 Male, age 18, unknown 628.5
Superior colliculus
nTPM: 744.0
2668 Female, age 75, unknown 1181.2
2087 Female, age 72, unknown 975.8
2261 Male, age 18, unknown 806.9
1796 Male, age 53, unknown 802.2
1913 Female, age 42, unknown 698.2
2587 Male, age 74, left hemisphere 671.1
2664 Male, age 75, both hemispheres 651.4
1995 Male, age 72, unknown 563.1
1839 Male, age 51, unknown 550.0
1895 Male, age 76, right hemisphere 540.5
Ventral tegmental area
nTPM: 775.1
2218 Male, age 76, both hemispheres 864.4
2410 Female, age 72, unknown 850.9
1915 Female, age 42, unknown 821.6
2223 Female, age 72, unknown 777.0
1942 Male, age 51, unknown 703.8
2021 Male, age 53, unknown 633.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 93.8
Samples: 183

Max nTPM: 378.3
Min nTPM: 37.8
Std nTPM: 46.4
Median nTPM: 82.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 378.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 355.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 253.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 222.0
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 206.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 203.6
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 186.7
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 180.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 174.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 168.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 158.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 157.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 157.5
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 155.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 155.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 146.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 145.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 144.6
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 142.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 141.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 141.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 136.6
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 134.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 133.9
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 133.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 132.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 130.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 129.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 127.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 127.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 126.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 126.4
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 126.0
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 124.4
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 121.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 120.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 119.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 117.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 117.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 114.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 110.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 110.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 110.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 109.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 107.1
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 106.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 106.2
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 105.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 104.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 104.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 103.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 102.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 102.1
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 100.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 100.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 99.7
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 99.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 98.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 98.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 98.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 97.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 96.6
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 96.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 95.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 94.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 94.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 94.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 93.6
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 93.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 92.8
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 92.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 92.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 91.8
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 91.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 89.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 88.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 88.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 87.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 87.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 86.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 86.4
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 86.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 86.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 85.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 85.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 85.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 84.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 83.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 83.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 82.7
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 82.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 82.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 81.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 81.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 81.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 81.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 80.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 80.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 79.8
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 79.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 79.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 78.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 78.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 78.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 77.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 77.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 77.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 77.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 77.3
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 77.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 76.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 76.9
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 76.9
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 76.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 76.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 75.5
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 75.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 75.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 75.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 73.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 73.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 71.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 71.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 70.5
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 70.4
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 70.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 69.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 69.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 69.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 68.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 68.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 67.9
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 67.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 66.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 66.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 65.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 64.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 64.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 63.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 63.8
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 63.4
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 63.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 61.8
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 60.8
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 60.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 59.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 59.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 59.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 58.2
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 57.4
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 57.4
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 57.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 57.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 57.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 56.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 56.5
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 56.3
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 55.8
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 55.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 54.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 54.8
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 54.7
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 54.6
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 54.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 53.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 51.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 51.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 50.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 49.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 49.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 49.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 48.6
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 48.6
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 48.3
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 48.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 47.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 46.8
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 46.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.4
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 41.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 38.6
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 37.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

358.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 358.6
FF:10158-103A5 76 years, female 358.6

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

562.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 556.8
Samples: 1

Max nTPM: 556.8
Min nTPM: 556.8
Sample A 556.8
Midbrain
nTPM: 445.3
Samples: 1

Max nTPM: 445.3
Min nTPM: 445.3
Sample A 445.3
Superior colliculi
nTPM: 562.8
Samples: 1

Max nTPM: 562.8
Min nTPM: 562.8
Sample A 562.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

501.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 501.4
Samples: 3

Max nTPM: 631.2
Min nTPM: 285.3
Sample A Female 587.7
Sample B Female 285.3
Sample C Male 631.2
Midbrain
nTPM: 442.3
Samples: 3

Max nTPM: 691.7
Min nTPM: 283.8
Sample B Female 283.8
Sample C Male 691.7
Sample D Male 351.4
Periaqueductal gray
nTPM: 276.7
Samples: 3

Max nTPM: 374.8
Min nTPM: 217.5
Sample B Female 237.7
Sample C Male 374.8
Sample D Male 217.5
Superior colliculi
nTPM: 432.9
Samples: 4

Max nTPM: 712.3
Min nTPM: 214.4
Sample A Female 368.8
Sample B Female 214.4
Sample C Male 712.3
Sample D Male 436.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

284.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 284.0
Samples: 4

Max nTPM: 323.1
Min nTPM: 213.3
Sample A 213.3
Sample B 286.7
Sample C 312.9
Sample D 323.1

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

347.8
Rat sample Sample description nTPM
Midbrain
nTPM: 347.8
Samples: 4

Max nTPM: 363.9
Min nTPM: 331.0
Sample A 363.9
Sample A 344.6
Sample A 331.0
Sample A 351.8

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