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EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:837.5 nTPM
FANTOM5:769.1 Scaled Tags Per Million
Macaque:365.0 nTPM
Mouse:399.2 nTPM
Rat:222.0 nTPM
Pig:225.9 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

837.5
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 496.5
2188 Female, age 91, both hemispheres 611.8
2090 Male, age 80, both hemispheres 604.9
1984 Male, age 76, both hemispheres 398.4
2301 Female, age 85, both hemispheres 371.0
Dorsal cochlear nucleus
nTPM: 738.0
2802 Male, age 74, right hemisphere 883.4
2378 Male, age 80, both hemispheres 837.1
2370 Male, age 61, both hemispheres 740.4
2058 Male, age 76, both hemispheres 691.7
2187 Female, age 91, both hemispheres 537.5
Dorsal tegmental nucleus
nTPM: 564.4
2083 Male, age 80, both hemispheres 821.3
2326 Male, age 74, both hemispheres 615.6
1936 Male, age 76, left hemisphere 430.0
2358 Male, age 61, both hemispheres 390.8
Dorsolateral tegmental area
nTPM: 524.6
2654 Male, age 80, both hemispheres 735.6
2751 Female, age 85, both hemispheres 705.0
2360 Male, age 74, both hemispheres 433.4
2337 Male, age 61, both hemispheres 408.3
2141 Male, age 76, both hemispheres 341.0
Kolliker-Fuse nucleus
nTPM: 585.3
2793 Female, age 91, left hemisphere 851.2
2163 Male, age 80, both hemispheres 592.9
2315 Male, age 76, right hemisphere 311.7
Lateral lemniscal nuclei
nTPM: 684.2
2453 Male, age 74, right hemisphere 835.7
2320 Female, age 91, left hemisphere 727.5
2169 Male, age 76, both hemispheres 672.5
2036 Male, age 80, both hemispheres 628.0
2746 Female, age 85, left hemisphere 557.4
Lateral parabrachial nucleus
nTPM: 655.4
2013 Male, age 80, both hemispheres 734.0
2792 Male, age 76, both hemispheres 670.7
2790 Male, age 61, both hemispheres 639.4
2139 Female, age 85, right hemisphere 577.7
Lateral vestibular nucleus
nTPM: 530.2
2184 Male, age 76, both hemispheres 571.2
2311 Male, age 80, both hemispheres 489.2
Locus coeruleus
nTPM: 442.7
2162 Male, age 80, both hemispheres 488.7
2317 Female, age 72, unknown 478.5
2014 Male, age 55, unknown 473.2
2720 Male, age 74, both hemispheres 459.8
2123 Female, age 91, both hemispheres 439.2
1980 Male, age 76, both hemispheres 383.0
2788 Male, age 74, unknown 376.6
Medial parabrachial nucleus
nTPM: 555.7
2463 Female, age 85, right hemisphere 667.8
2854 Male, age 80, both hemispheres 562.7
2156 Male, age 61, both hemispheres 540.7
2786 Male, age 76, both hemispheres 522.1
2170 Female, age 91, both hemispheres 485.2
Medial periolivary nuclei
nTPM: 669.7
2458 Female, age 91, both hemispheres 836.4
2081 Male, age 80, both hemispheres 710.0
2063 Male, age 76, both hemispheres 701.1
2171 Female, age 85, both hemispheres 570.8
2791 Male, age 74, right hemisphere 530.3
Motor facial nucleus
nTPM: 746.3
2795 Female, age 91, both hemispheres 919.3
2126 Male, age 61, both hemispheres 792.7
2327 Male, age 80, both hemispheres 707.4
2062 Male, age 76, both hemispheres 703.2
2365 Male, age 74, right hemisphere 697.5
2697 Female, age 85, both hemispheres 657.7
Motor trigeminal nucleus
nTPM: 626.8
2560 Male, age 74, both hemispheres 799.8
2321 Female, age 91, both hemispheres 657.9
2079 Male, age 80, both hemispheres 622.4
2309 Male, age 76, both hemispheres 553.7
2335 Male, age 61, both hemispheres 500.2
Nuclei of the trapezoid body
nTPM: 702.7
2368 Female, age 91, both hemispheres 902.3
1983 Male, age 76, both hemispheres 722.1
2166 Male, age 80, both hemispheres 702.0
2159 Male, age 61, both hemispheres 666.4
2735 Female, age 85, both hemispheres 520.6
Nucleus raphe magnus
nTPM: 776.6
2459 Female, age 91, both hemispheres 1264.7
2328 Male, age 80, both hemispheres 808.9
2051 Male, age 76, both hemispheres 787.9
2160 Male, age 61, both hemispheres 638.7
2172 Female, age 85, both hemispheres 588.9
2455 Male, age 74, both hemispheres 570.3
Paramedian reticular nucleus
nTPM: 654.9
2050 Female, age 85, both hemispheres 758.6
2057 Male, age 80, both hemispheres 711.1
2313 Male, age 61, both hemispheres 627.2
2052 Male, age 76, both hemispheres 522.6
Pedunculopontine tegmental nucleus
nTPM: 497.4
2334 Male, age 80, both hemispheres 623.8
1921 Female, age 85, both hemispheres 483.4
2338 Male, age 61, both hemispheres 384.9
Pontine nuclei
nTPM: 736.3
2454 Male, age 74, left hemisphere 868.3
2727 Male, age 61, right hemisphere 848.3
1863 Male, age 55, unknown 801.7
1968 Male, age 76, left hemisphere 780.7
2787 Female, age 85, both hemispheres 764.4
2109 Female, age 72, unknown 618.6
2115 Male, age 80, left hemisphere 609.3
2319 Female, age 91, both hemispheres 599.2
Pontine raphe nucleus
nTPM: 578.8
2122 Female, age 85, midline 662.8
2853 Male, age 76, midline 494.8
Posteroventral cochlear nucleus
nTPM: 658.6
2371 Male, age 61, both hemispheres 758.5
2341 Male, age 80, both hemispheres 717.5
2070 Male, age 76, both hemispheres 672.1
2752 Female, age 85, both hemispheres 654.1
2135 Female, age 91, both hemispheres 491.0
Principal sensory trigeminal nucleus
nTPM: 572.3
2367 Female, age 91, left hemisphere 704.2
2158 Male, age 61, both hemispheres 561.2
2008 Male, age 80, left hemisphere 549.0
2324 Male, age 76, both hemispheres 474.7
Reticular pontine nucleus, caudal
nTPM: 837.5
2457 Female, age 91, both hemispheres 1182.4
2092 Male, age 76, both hemispheres 749.6
2559 Male, age 74, both hemispheres 717.7
2332 Male, age 80, right hemisphere 700.4
Reticular pontine nucleus, oral
nTPM: 730.8
2361 Male, age 74, both hemispheres 887.4
1939 Male, age 80, both hemispheres 755.7
2012 Female, age 85, both hemispheres 684.9
2366 Female, age 91, both hemispheres 680.7
2167 Male, age 76, both hemispheres 645.4
Reticulotegmental nucleus
nTPM: 799.4
2322 Female, age 91, both hemispheres 1085.0
2452 Male, age 74, both hemispheres 888.5
2333 Male, age 80, both hemispheres 814.9
2325 Male, age 76, both hemispheres 409.2
Spinal trigeminal nucleus, oral
nTPM: 627.4
2164 Male, age 80, both hemispheres 743.8
1978 Male, age 76, both hemispheres 601.5
2737 Female, age 85, both hemispheres 537.0
Subcoeruleus area
nTPM: 598.7
2369 Female, age 85, left hemisphere 829.8
2451 Male, age 74, both hemispheres 600.2
1958 Male, age 80, both hemispheres 531.4
2089 Male, age 76, left hemisphere 527.5
2323 Female, age 91, left hemisphere 504.5
Superior olive
nTPM: 686.8
2020 Male, age 76, both hemispheres 774.6
2561 Female, age 91, both hemispheres 766.6
2329 Male, age 80, right hemisphere 694.9
1875 Female, age 85, both hemispheres 650.9
2364 Male, age 74, right hemisphere 547.1
Ventral periolivary nuclei
nTPM: 589.0
2023 Male, age 76, both hemispheres 720.9
2165 Male, age 80, both hemispheres 685.2
2794 Female, age 91, left hemisphere 536.9
2130 Female, age 85, both hemispheres 413.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 746.1
2456 Female, age 91, both hemispheres 1192.4
2449 Male, age 74, both hemispheres 716.7
2840 Female, age 85, both hemispheres 712.3
2161 Male, age 80, both hemispheres 704.5
1959 Male, age 76, both hemispheres 630.4
2359 Male, age 61, both hemispheres 520.6

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

769.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 769.1
FF:10165-103B3 76 years, female 846.0
FF:10182-103D2 60 years, female 692.2
Pons
Scaled Tags Per Million: 527.7
FF:10033-101E6 18-54 years, mixed 527.7

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

365.0
Macaque sample Sample description nTPM
Pons
nTPM: 365.0
Samples: 2

Max nTPM: 401.0
Min nTPM: 329.0
Sample A 401.0
Sample B 329.0

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

225.9
Pig sample Sample description nTPM
Pons
nTPM: 225.9
Samples: 3

Max nTPM: 308.0
Min nTPM: 180.9
Sample A Female 188.7
Sample B Female 180.9
Sample C Male 308.0

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

399.2
Mouse sample Sample description nTPM
Pons
nTPM: 399.3
Samples: 4

Max nTPM: 438.6
Min nTPM: 357.8
Sample A 412.1
Sample B 357.8
Sample C 438.6
Sample D 388.5

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

222.0
Rat sample Sample description nTPM
Pons
nTPM: 222.0
Samples: 4

Max nTPM: 277.5
Min nTPM: 189.1
Sample A 200.6
Sample A 277.5
Sample A 189.1
Sample A 220.7

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