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BETA
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  • RPL9
EVOLUTIONARY PONS Show tissue menu
BRAIN72 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX
FRONTAL CORTEX FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS
MIDDLE TEMPORAL GYRUS MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX
SEPTAL AREA SEPTUM SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

68.173
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:98.3 nTPM
FANTOM5:30.7 Scaled Tags Per Million
Macaque:11.1 nTPM
Rat:0.9 nTPM
Pig:27.6 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity.

, antibody HPA003372
Pons mean intensity 68.173
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus -
Parabrachial nucleus -
Principle sensory trigeminal nucleus -
Locus coeruleus 68.173
Pontine nucleus 15.911
Vestibular nucleus 16.537
Pontine reticular nucleus, oral 9.128
Lateral lemniscus 12.824
Superior paraolivary nucleus 3.954

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 87.8
2090 Male, age 80, both hemispheres 109.4
2188 Female, age 91, both hemispheres 95.8
1984 Male, age 76, both hemispheres 81.1
2301 Female, age 85, both hemispheres 64.9
Dorsal cochlear nucleus
nTPM: 84.6
2802 Male, age 74, right hemisphere 105.8
2378 Male, age 80, both hemispheres 89.7
2187 Female, age 91, both hemispheres 85.6
2370 Male, age 61, both hemispheres 77.2
2058 Male, age 76, both hemispheres 64.9
Dorsal tegmental nucleus
nTPM: 73.6
2083 Male, age 80, both hemispheres 84.8
2326 Male, age 74, both hemispheres 80.9
1936 Male, age 76, left hemisphere 67.3
2358 Male, age 61, both hemispheres 61.5
Dorsolateral tegmental area
nTPM: 90.6
2654 Male, age 80, both hemispheres 133.1
2751 Female, age 85, both hemispheres 89.0
2337 Male, age 61, both hemispheres 85.3
2360 Male, age 74, both hemispheres 79.1
2141 Male, age 76, both hemispheres 66.3
Kolliker-Fuse nucleus
nTPM: 83.5
2315 Male, age 76, right hemisphere 92.0
2163 Male, age 80, both hemispheres 81.4
2793 Female, age 91, left hemisphere 77.0
Lateral lemniscal nuclei
nTPM: 70.8
2169 Male, age 76, both hemispheres 79.0
2036 Male, age 80, both hemispheres 76.8
2746 Female, age 85, left hemisphere 75.0
2453 Male, age 74, right hemisphere 62.3
2320 Female, age 91, left hemisphere 60.8
Lateral parabrachial nucleus
nTPM: 81.8
2792 Male, age 76, both hemispheres 95.7
2013 Male, age 80, both hemispheres 88.9
2139 Female, age 85, right hemisphere 78.9
2790 Male, age 61, both hemispheres 63.7
Lateral vestibular nucleus
nTPM: 65.2
2311 Male, age 80, both hemispheres 68.4
2184 Male, age 76, both hemispheres 62.1
Locus coeruleus
nTPM: 75.3
2014 Male, age 55, unknown 122.6
2123 Female, age 91, both hemispheres 78.1
2788 Male, age 74, unknown 71.2
2317 Female, age 72, unknown 69.9
2720 Male, age 74, both hemispheres 65.6
2162 Male, age 80, both hemispheres 61.8
1980 Male, age 76, both hemispheres 57.6
Medial parabrachial nucleus
nTPM: 76.6
2170 Female, age 91, both hemispheres 103.7
2463 Female, age 85, right hemisphere 84.5
2786 Male, age 76, both hemispheres 68.3
2156 Male, age 61, both hemispheres 64.3
2854 Male, age 80, both hemispheres 62.2
Medial periolivary nuclei
nTPM: 83.0
2081 Male, age 80, both hemispheres 110.6
2063 Male, age 76, both hemispheres 91.6
2791 Male, age 74, right hemisphere 84.8
2458 Female, age 91, both hemispheres 67.0
2171 Female, age 85, both hemispheres 60.8
Motor facial nucleus
nTPM: 72.5
2062 Male, age 76, both hemispheres 84.6
2795 Female, age 91, both hemispheres 80.5
2365 Male, age 74, right hemisphere 80.4
2126 Male, age 61, both hemispheres 75.8
2697 Female, age 85, both hemispheres 62.5
2327 Male, age 80, both hemispheres 50.9
Motor trigeminal nucleus
nTPM: 78.2
2079 Male, age 80, both hemispheres 84.9
2560 Male, age 74, both hemispheres 84.0
2335 Male, age 61, both hemispheres 77.5
2309 Male, age 76, both hemispheres 74.6
2321 Female, age 91, both hemispheres 70.0
Nuclei of the trapezoid body
nTPM: 72.9
1983 Male, age 76, both hemispheres 102.7
2166 Male, age 80, both hemispheres 70.5
2159 Male, age 61, both hemispheres 66.2
2368 Female, age 91, both hemispheres 63.9
2735 Female, age 85, both hemispheres 61.1
Nucleus raphe magnus
nTPM: 62.7
2051 Male, age 76, both hemispheres 75.5
2459 Female, age 91, both hemispheres 71.5
2160 Male, age 61, both hemispheres 68.9
2172 Female, age 85, both hemispheres 61.1
2455 Male, age 74, both hemispheres 54.7
2328 Male, age 80, both hemispheres 44.5
Paramedian reticular nucleus
nTPM: 87.2
2057 Male, age 80, both hemispheres 101.6
2052 Male, age 76, both hemispheres 87.9
2050 Female, age 85, both hemispheres 83.5
2313 Male, age 61, both hemispheres 75.9
Pedunculopontine tegmental nucleus
nTPM: 75.6
2338 Male, age 61, both hemispheres 84.1
2334 Male, age 80, both hemispheres 75.5
1921 Female, age 85, both hemispheres 67.4
Pontine nuclei
nTPM: 81.5
2109 Female, age 72, unknown 99.9
1968 Male, age 76, left hemisphere 87.0
2115 Male, age 80, left hemisphere 83.7
2454 Male, age 74, left hemisphere 81.9
2319 Female, age 91, both hemispheres 80.9
2727 Male, age 61, right hemisphere 75.3
1863 Male, age 55, unknown 72.1
2787 Female, age 85, both hemispheres 71.0
Pontine raphe nucleus
nTPM: 76.8
2122 Female, age 85, midline 80.1
2853 Male, age 76, midline 73.6
Posteroventral cochlear nucleus
nTPM: 98.3
2341 Male, age 80, both hemispheres 138.2
2135 Female, age 91, both hemispheres 100.9
2371 Male, age 61, both hemispheres 93.0
2752 Female, age 85, both hemispheres 83.2
2070 Male, age 76, both hemispheres 76.1
Principal sensory trigeminal nucleus
nTPM: 68.0
2008 Male, age 80, left hemisphere 72.6
2158 Male, age 61, both hemispheres 70.4
2367 Female, age 91, left hemisphere 69.5
2324 Male, age 76, both hemispheres 59.7
Reticular pontine nucleus, caudal
nTPM: 84.1
2559 Male, age 74, both hemispheres 120.2
2092 Male, age 76, both hemispheres 86.0
2457 Female, age 91, both hemispheres 76.8
2332 Male, age 80, right hemisphere 53.4
Reticular pontine nucleus, oral
nTPM: 74.8
2366 Female, age 91, both hemispheres 81.2
2012 Female, age 85, both hemispheres 78.4
2361 Male, age 74, both hemispheres 77.7
2167 Male, age 76, both hemispheres 75.0
1939 Male, age 80, both hemispheres 61.8
Reticulotegmental nucleus
nTPM: 69.6
2452 Male, age 74, both hemispheres 76.7
2322 Female, age 91, both hemispheres 72.9
2325 Male, age 76, both hemispheres 67.4
2333 Male, age 80, both hemispheres 61.4
Spinal trigeminal nucleus, oral
nTPM: 70.8
1978 Male, age 76, both hemispheres 73.4
2737 Female, age 85, both hemispheres 70.0
2164 Male, age 80, both hemispheres 68.9
Subcoeruleus area
nTPM: 80.1
2451 Male, age 74, both hemispheres 109.5
2369 Female, age 85, left hemisphere 93.6
2323 Female, age 91, left hemisphere 69.6
2089 Male, age 76, left hemisphere 68.0
1958 Male, age 80, both hemispheres 59.9
Superior olive
nTPM: 75.1
2364 Male, age 74, right hemisphere 94.7
2020 Male, age 76, both hemispheres 92.0
1875 Female, age 85, both hemispheres 77.0
2561 Female, age 91, both hemispheres 70.3
2329 Male, age 80, right hemisphere 41.3
Ventral periolivary nuclei
nTPM: 68.4
2023 Male, age 76, both hemispheres 90.6
2794 Female, age 91, left hemisphere 72.0
2165 Male, age 80, both hemispheres 63.3
2130 Female, age 85, both hemispheres 47.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 70.3
1959 Male, age 76, both hemispheres 75.1
2359 Male, age 61, both hemispheres 73.6
2161 Male, age 80, both hemispheres 72.9
2840 Female, age 85, both hemispheres 72.4
2456 Female, age 91, both hemispheres 68.7
2449 Male, age 74, both hemispheres 59.3

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

30.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 24.5
FF:10182-103D2 60 years, female 24.6
FF:10165-103B3 76 years, female 24.4
Pons
Scaled Tags Per Million: 30.7
FF:10033-101E6 18-54 years, mixed 30.7

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11.1
Macaque sample Sample description nTPM
Pons
nTPM: 11.1
Samples: 2

Max nTPM: 11.5
Min nTPM: 10.7
Sample A 11.5
Sample B 10.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.6
Pig sample Sample description nTPM
Pons
nTPM: 27.6
Samples: 3

Max nTPM: 33.3
Min nTPM: 21.3
Sample A Female 28.2
Sample B Female 21.3
Sample C Male 33.3

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.9
Rat sample Sample description nTPM
Pons
nTPM: 0.9
Samples: 4

Max nTPM: 1.2
Min nTPM: 0.7
Sample A 1.2
Sample A 1.1
Sample A 0.7
Sample A 0.7

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