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BETA
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  • LRRC8D
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:21.3 nTPM
HPA Brain:93.1 nTPM
GTEx:21.3 nTPM
FANTOM5:129.4 Scaled Tags Per Million
Macaque:40.8 nTPM
Mouse:18.5 nTPM
Rat:21.2 nTPM
Pig:32.1 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 30
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 60
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 77.8
2019 Male, age 18, unknown 99.3
2411 Female, age 72, unknown 94.2
1830 Male, age 51, unknown 93.1
1833 Male, age 53, unknown 90.5
1870 Female, age 42, unknown 82.7
2586 Male, age 75, left hemisphere 69.6
2828 Female, age 72, unknown 68.0
2219 Male, age 76, both hemispheres 64.3
1827 Male, age 72, unknown 59.7
2666 Male, age 74, left hemisphere 57.0
Dorsal raphe nucleus
nTPM: 68.9
2750 Male, age 76, both hemispheres 106.3
2016 Female, age 72, unknown 66.6
1828 Male, age 53, unknown 61.6
2047 Male, age 72, unknown 55.5
2298 Female, age 72, unknown 54.2
Inferior colliculus
nTPM: 60.5
1890 Male, age 53, unknown 65.0
2097 Female, age 72, unknown 59.9
1848 Female, age 42, unknown 59.3
2849 Male, age 72, unknown 58.0
Median raphe nucleus
nTPM: 59.8
2220 Male, age 76, midline 59.8
Periaquaductal grey, anterior
nTPM: 60.5
1947 Male, age 18, unknown 65.2
2502 Female, age 75, unknown 65.2
1795 Male, age 51, unknown 51.0
Periaquaductal grey, dorsal
nTPM: 49.3
2464 Female, age 72, unknown 60.5
1831 Male, age 72, unknown 49.6
2850 Male, age 76, both hemispheres 46.0
1840 Male, age 53, unknown 41.3
Periaquaductal grey, lateral
nTPM: 61.0
2272 Male, age 74, both hemispheres 75.2
2053 Male, age 18, unknown 54.6
2140 Male, age 76, both hemispheres 53.1
Pretectal area
nTPM: 61.4
2273 Male, age 74, both hemispheres 76.5
2316 Male, age 76, right hemisphere 72.6
1815 Male, age 53, unknown 68.2
2007 Male, age 72, unknown 66.7
2407 Male, age 75, both hemispheres 62.8
1817 Female, age 42, unknown 61.8
2224 Female, age 72, unknown 58.1
2667 Female, age 75, unknown 55.9
2825 Male, age 18, unknown 55.2
1944 Female, age 72, unknown 50.7
1816 Male, age 51, unknown 46.6
Red nucleus
nTPM: 93.1
1904 Male, age 53, unknown 111.9
1865 Male, age 51, unknown 106.4
2227 Male, age 72, unknown 105.0
2785 Male, age 18, unknown 103.8
2769 Male, age 72, unknown 101.8
2503 Female, age 72, unknown 101.0
1821 Female, age 72, unknown 91.6
2588 Male, age 74, left hemisphere 87.2
1954 Female, age 42, unknown 86.8
2823 Male, age 76, right hemisphere 85.9
2584 Male, age 75, left hemisphere 69.4
2725 Female, age 75, unknown 66.8
Substantia nigra
nTPM: 61.0
2583 Male, age 75, right hemisphere 77.0
2590 Female, age 75, unknown 74.7
1889 Female, age 72, unknown 66.6
1851 Male, age 51, unknown 66.0
2409 Female, age 72, unknown 60.6
1941 Male, age 53, unknown 59.2
2699 Male, age 18, unknown 54.1
1916 Female, age 42, unknown 53.8
2241 Male, age 72, unknown 51.4
2665 Male, age 74, both hemispheres 46.1
Superior colliculus
nTPM: 68.3
1913 Female, age 42, unknown 93.8
1995 Male, age 72, unknown 88.9
2668 Female, age 75, unknown 74.3
1895 Male, age 76, right hemisphere 73.8
2587 Male, age 74, left hemisphere 72.8
1839 Male, age 51, unknown 68.1
1796 Male, age 53, unknown 56.8
2261 Male, age 18, unknown 56.6
2664 Male, age 75, both hemispheres 51.4
2087 Female, age 72, unknown 46.9
Ventral tegmental area
nTPM: 69.4
2223 Female, age 72, unknown 81.9
2410 Female, age 72, unknown 79.6
1942 Male, age 51, unknown 67.0
1915 Female, age 42, unknown 63.8
2218 Male, age 76, both hemispheres 63.4
2021 Male, age 53, unknown 60.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 21.3
Samples: 183

Max nTPM: 60.9
Min nTPM: 6.7
Std nTPM: 10.1
Median nTPM: 18.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 60.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 56.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 50.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 48.9
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 48.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 48.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 44.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 44.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 44.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 43.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 42.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 41.0
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 40.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 39.7
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 38.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 36.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 36.0
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 34.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 34.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 34.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 33.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 33.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 33.6
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 33.2
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 33.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 32.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 31.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 31.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 31.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 31.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 31.6
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 31.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 30.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 30.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 30.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 29.1
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 29.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 27.7
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 27.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 27.5
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 27.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 26.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 26.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 26.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 26.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 26.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 26.0
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 25.8
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 25.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 25.3
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 24.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 23.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 23.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 23.8
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 23.3
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 23.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 23.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 23.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 23.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 22.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 21.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 21.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 21.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 21.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 21.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 21.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 21.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 20.8
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 20.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 20.8
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 20.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 20.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 20.5
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 20.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 19.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 19.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 19.1
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 19.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 19.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 19.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 18.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 18.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 18.7
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 18.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 18.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 18.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 18.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 18.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 18.3
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 18.3
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 18.2
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 18.1
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 18.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 17.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 17.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 17.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 17.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 17.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 17.8
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 17.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 17.5
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 17.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 17.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 17.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 17.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 17.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 16.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 16.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 16.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 16.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 16.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 16.2
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 16.1
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 16.0
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 15.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 15.9
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 15.9
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 15.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 15.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 15.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 15.8
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 15.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 15.5
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 15.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 15.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 15.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 15.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 14.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 14.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 14.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 14.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 14.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 14.6
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 14.6
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 14.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 14.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 13.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 13.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 13.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 13.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 13.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 13.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 13.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 13.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 13.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 13.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 13.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 12.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 12.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 12.6
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 12.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 12.5
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 12.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 12.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 12.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 12.2
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 12.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 12.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 12.0
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 11.9
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 11.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 11.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 11.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 11.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 10.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 10.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 10.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 10.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 10.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 10.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 9.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 9.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 9.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 8.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 8.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 8.8
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 8.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 8.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 6.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

129.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 129.4
FF:10158-103A5 76 years, female 129.4

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 40.8
Samples: 1

Max nTPM: 40.8
Min nTPM: 40.8
Sample A 40.8
Midbrain
nTPM: 26.7
Samples: 1

Max nTPM: 26.7
Min nTPM: 26.7
Sample A 26.7
Superior colliculi
nTPM: 33.3
Samples: 1

Max nTPM: 33.3
Min nTPM: 33.3
Sample A 33.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 32.1
Samples: 3

Max nTPM: 35.4
Min nTPM: 25.6
Sample A Female 35.4
Sample B Female 25.6
Sample C Male 35.4
Midbrain
nTPM: 27.0
Samples: 3

Max nTPM: 29.3
Min nTPM: 24.9
Sample B Female 26.7
Sample C Male 29.3
Sample D Male 24.9
Periaqueductal gray
nTPM: 24.5
Samples: 3

Max nTPM: 26.9
Min nTPM: 22.3
Sample B Female 24.4
Sample C Male 26.9
Sample D Male 22.3
Superior colliculi
nTPM: 32.1
Samples: 4

Max nTPM: 34.9
Min nTPM: 27.5
Sample A Female 34.9
Sample B Female 27.5
Sample C Male 34.8
Sample D Male 31.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

18.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 18.5
Samples: 4

Max nTPM: 19.5
Min nTPM: 16.8
Sample A 16.8
Sample B 19.3
Sample C 19.5
Sample D 18.4

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

21.2
Rat sample Sample description nTPM
Midbrain
nTPM: 21.2
Samples: 4

Max nTPM: 21.9
Min nTPM: 20.3
Sample A 20.3
Sample A 21.9
Sample A 21.7
Sample A 20.9

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