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BETA
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  • RAB1B
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:98.0 nTPM
HPA Brain:129.7 nTPM
GTEx:98.0 nTPM
FANTOM5:83.4 Scaled Tags Per Million
Macaque:66.8 nTPM
Mouse:92.5 nTPM
Rat:66.2 nTPM
Pig:167.5 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 20
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 50
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

129.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 125.7
2586 Male, age 75, left hemisphere 178.8
2666 Male, age 74, left hemisphere 135.2
2828 Female, age 72, unknown 130.5
2019 Male, age 18, unknown 126.4
1827 Male, age 72, unknown 122.9
1833 Male, age 53, unknown 115.9
1870 Female, age 42, unknown 114.8
1830 Male, age 51, unknown 111.9
2411 Female, age 72, unknown 110.8
2219 Male, age 76, both hemispheres 109.5
Dorsal raphe nucleus
nTPM: 112.2
2047 Male, age 72, unknown 116.9
1828 Male, age 53, unknown 116.3
2750 Male, age 76, both hemispheres 113.7
2298 Female, age 72, unknown 108.6
2016 Female, age 72, unknown 105.6
Inferior colliculus
nTPM: 110.0
2849 Male, age 72, unknown 117.2
1890 Male, age 53, unknown 112.1
1848 Female, age 42, unknown 109.4
2097 Female, age 72, unknown 101.2
Median raphe nucleus
nTPM: 114.5
2220 Male, age 76, midline 114.5
Periaquaductal grey, anterior
nTPM: 123.0
2502 Female, age 75, unknown 127.7
1795 Male, age 51, unknown 123.2
1947 Male, age 18, unknown 118.2
Periaquaductal grey, dorsal
nTPM: 107.5
2850 Male, age 76, both hemispheres 111.9
1840 Male, age 53, unknown 110.0
1831 Male, age 72, unknown 104.6
2464 Female, age 72, unknown 103.4
Periaquaductal grey, lateral
nTPM: 99.6
2140 Male, age 76, both hemispheres 102.8
2272 Male, age 74, both hemispheres 98.9
2053 Male, age 18, unknown 97.1
Pretectal area
nTPM: 117.1
1817 Female, age 42, unknown 141.1
1816 Male, age 51, unknown 138.1
2007 Male, age 72, unknown 131.6
1944 Female, age 72, unknown 131.1
1815 Male, age 53, unknown 127.7
2667 Female, age 75, unknown 121.5
2407 Male, age 75, both hemispheres 111.5
2825 Male, age 18, unknown 106.2
2224 Female, age 72, unknown 98.1
2273 Male, age 74, both hemispheres 94.8
2316 Male, age 76, right hemisphere 86.9
Red nucleus
nTPM: 121.9
2584 Male, age 75, left hemisphere 148.0
2785 Male, age 18, unknown 134.4
2588 Male, age 74, left hemisphere 126.4
2769 Male, age 72, unknown 124.5
1865 Male, age 51, unknown 123.2
1904 Male, age 53, unknown 120.6
1821 Female, age 72, unknown 117.8
2227 Male, age 72, unknown 117.3
1954 Female, age 42, unknown 114.9
2503 Female, age 72, unknown 114.9
2823 Male, age 76, right hemisphere 110.9
2725 Female, age 75, unknown 110.1
Substantia nigra
nTPM: 129.7
1916 Female, age 42, unknown 159.5
1851 Male, age 51, unknown 142.2
2665 Male, age 74, both hemispheres 140.9
2583 Male, age 75, right hemisphere 140.3
2699 Male, age 18, unknown 130.8
1941 Male, age 53, unknown 129.5
1889 Female, age 72, unknown 127.2
2590 Female, age 75, unknown 117.2
2241 Male, age 72, unknown 106.6
2409 Female, age 72, unknown 102.4
Superior colliculus
nTPM: 120.6
2664 Male, age 75, both hemispheres 154.9
2668 Female, age 75, unknown 133.1
2087 Female, age 72, unknown 124.2
2261 Male, age 18, unknown 121.8
1995 Male, age 72, unknown 119.9
1796 Male, age 53, unknown 118.6
1913 Female, age 42, unknown 117.7
1839 Male, age 51, unknown 110.2
2587 Male, age 74, left hemisphere 105.2
1895 Male, age 76, right hemisphere 100.3
Ventral tegmental area
nTPM: 121.7
2410 Female, age 72, unknown 135.4
1915 Female, age 42, unknown 127.7
2218 Male, age 76, both hemispheres 125.0
2223 Female, age 72, unknown 122.7
2021 Male, age 53, unknown 110.1
1942 Male, age 51, unknown 109.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 98.0
Samples: 183

Max nTPM: 194.4
Min nTPM: 57.2
Std nTPM: 16.3
Median nTPM: 96.4
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 194.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 177.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 145.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 134.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 130.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 129.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 128.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 124.2
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 124.2
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 123.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 122.3
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 118.8
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 118.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 118.4
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 118.2
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 117.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 116.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 115.4
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 115.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 114.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 114.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 113.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 113.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 113.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 113.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 113.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 111.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 110.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 110.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 110.2
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 110.2
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 110.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 109.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 109.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 109.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 108.8
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 107.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 107.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 107.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 107.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 106.8
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 105.6
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 105.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 104.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 104.4
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 104.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 103.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 103.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 103.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 102.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 102.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 102.6
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 102.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 102.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 102.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 102.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 102.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 101.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 101.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 101.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 101.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 101.5
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 101.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 101.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 101.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 101.2
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 101.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 100.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 99.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 99.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 99.4
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 99.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 99.1
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 98.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 98.8
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 98.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 98.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 98.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 98.5
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 98.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 98.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 97.7
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 97.4
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 97.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 97.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 97.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 97.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 96.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 96.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 96.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 96.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 96.4
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 96.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 96.1
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 96.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 95.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 95.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 95.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 95.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 95.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 95.0
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 94.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 94.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 94.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 94.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 94.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 94.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 94.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 94.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 94.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 94.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 94.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 93.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 93.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 93.5
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 93.3
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 93.0
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 93.0
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 93.0
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 92.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 91.8
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 91.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 91.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 91.2
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 90.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 90.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 90.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 90.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 90.1
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 89.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 89.5
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 89.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 88.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 88.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 88.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 88.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 88.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 87.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 87.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 87.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 87.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 87.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 86.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 86.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 86.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 86.6
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 86.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 86.5
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 85.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 85.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 84.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 84.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 84.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 84.6
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 83.8
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 83.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 83.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 83.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 83.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 83.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 83.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 83.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 82.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 82.1
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 81.2
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 80.5
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 80.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 79.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 77.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 77.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 77.7
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 77.5
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 77.5
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 77.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 77.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 76.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 73.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 73.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 69.2
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 62.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 61.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 57.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

83.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 83.4
FF:10158-103A5 76 years, female 83.4

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 40.4
Samples: 1

Max nTPM: 40.4
Min nTPM: 40.4
Sample A 40.4
Midbrain
nTPM: 50.3
Samples: 1

Max nTPM: 50.3
Min nTPM: 50.3
Sample A 50.3
Superior colliculi
nTPM: 66.8
Samples: 1

Max nTPM: 66.8
Min nTPM: 66.8
Sample A 66.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

167.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 125.5
Samples: 3

Max nTPM: 142.9
Min nTPM: 95.3
Sample A Female 138.3
Sample B Female 95.3
Sample C Male 142.9
Midbrain
nTPM: 167.5
Samples: 3

Max nTPM: 272.7
Min nTPM: 101.6
Sample B Female 101.6
Sample C Male 272.7
Sample D Male 128.3
Periaqueductal gray
nTPM: 95.7
Samples: 3

Max nTPM: 117.5
Min nTPM: 83.6
Sample B Female 83.6
Sample C Male 117.5
Sample D Male 86.0
Superior colliculi
nTPM: 122.8
Samples: 4

Max nTPM: 139.3
Min nTPM: 93.2
Sample A Female 130.4
Sample B Female 93.2
Sample C Male 139.3
Sample D Male 128.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

92.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 92.5
Samples: 4

Max nTPM: 100.7
Min nTPM: 88.8
Sample A 91.3
Sample B 100.7
Sample C 89.1
Sample D 88.8

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.2
Rat sample Sample description nTPM
Midbrain
nTPM: 66.2
Samples: 4

Max nTPM: 67.3
Min nTPM: 63.9
Sample A 66.9
Sample A 66.8
Sample A 67.3
Sample A 63.9

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