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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:9.6 nTPM
HPA Brain:24.3 nTPM
GTEx:9.6 nTPM
FANTOM5:42.9 Scaled Tags Per Million
Pig:32.7 nTPM
Mouse:0.8 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 11.0
2586 Male, age 75, left hemisphere 20.7
2828 Female, age 72, unknown 15.4
1827 Male, age 72, unknown 11.3
1870 Female, age 42, unknown 11.1
2666 Male, age 74, left hemisphere 11.1
1833 Male, age 53, unknown 9.9
1830 Male, age 51, unknown 9.3
2411 Female, age 72, unknown 7.8
2019 Male, age 18, unknown 7.4
2219 Male, age 76, both hemispheres 5.7
Dorsal raphe nucleus
nTPM: 16.6
2298 Female, age 72, unknown 20.5
2047 Male, age 72, unknown 20.2
2016 Female, age 72, unknown 16.7
1828 Male, age 53, unknown 15.4
2750 Male, age 76, both hemispheres 10.3
Inferior colliculus
nTPM: 10.9
1890 Male, age 53, unknown 15.1
2097 Female, age 72, unknown 11.9
1848 Female, age 42, unknown 8.4
2849 Male, age 72, unknown 8.4
Median raphe nucleus
nTPM: 11.7
2220 Male, age 76, midline 11.7
Periaquaductal grey, anterior
nTPM: 24.3
1947 Male, age 18, unknown 38.3
1795 Male, age 51, unknown 21.1
2502 Female, age 75, unknown 13.5
Periaquaductal grey, dorsal
nTPM: 16.7
2850 Male, age 76, both hemispheres 22.8
1840 Male, age 53, unknown 16.8
1831 Male, age 72, unknown 16.5
2464 Female, age 72, unknown 10.7
Periaquaductal grey, lateral
nTPM: 17.9
2140 Male, age 76, both hemispheres 22.1
2053 Male, age 18, unknown 15.9
2272 Male, age 74, both hemispheres 15.7
Pretectal area
nTPM: 10.7
2273 Male, age 74, both hemispheres 16.7
2224 Female, age 72, unknown 13.4
2825 Male, age 18, unknown 13.3
2667 Female, age 75, unknown 13.0
2407 Male, age 75, both hemispheres 10.4
1817 Female, age 42, unknown 9.4
1944 Female, age 72, unknown 9.3
2316 Male, age 76, right hemisphere 9.1
1815 Male, age 53, unknown 8.5
1816 Male, age 51, unknown 8.5
2007 Male, age 72, unknown 5.9
Red nucleus
nTPM: 10.6
2725 Female, age 75, unknown 17.2
1821 Female, age 72, unknown 15.3
2823 Male, age 76, right hemisphere 11.7
1954 Female, age 42, unknown 11.5
2584 Male, age 75, left hemisphere 11.2
1865 Male, age 51, unknown 10.9
2227 Male, age 72, unknown 9.7
2503 Female, age 72, unknown 9.5
1904 Male, age 53, unknown 9.2
2769 Male, age 72, unknown 8.7
2588 Male, age 74, left hemisphere 7.3
2785 Male, age 18, unknown 5.3
Substantia nigra
nTPM: 19.7
1851 Male, age 51, unknown 30.2
1916 Female, age 42, unknown 25.8
2409 Female, age 72, unknown 24.2
2241 Male, age 72, unknown 23.7
2699 Male, age 18, unknown 22.2
1941 Male, age 53, unknown 16.7
2583 Male, age 75, right hemisphere 15.5
2590 Female, age 75, unknown 15.2
1889 Female, age 72, unknown 12.3
2665 Male, age 74, both hemispheres 11.5
Superior colliculus
nTPM: 11.5
1995 Male, age 72, unknown 16.8
2664 Male, age 75, both hemispheres 12.6
1796 Male, age 53, unknown 12.2
2087 Female, age 72, unknown 11.9
2261 Male, age 18, unknown 11.9
2668 Female, age 75, unknown 11.1
2587 Male, age 74, left hemisphere 10.9
1913 Female, age 42, unknown 10.5
1839 Male, age 51, unknown 8.6
1895 Male, age 76, right hemisphere 8.4
Ventral tegmental area
nTPM: 17.3
1915 Female, age 42, unknown 28.7
1942 Male, age 51, unknown 17.7
2021 Male, age 53, unknown 17.5
2218 Male, age 76, both hemispheres 14.1
2410 Female, age 72, unknown 13.1
2223 Female, age 72, unknown 12.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

9.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 9.6
Samples: 139

Max nTPM: 44.8
Min nTPM: 1.1
Std nTPM: 6.9
Median nTPM: 7.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 44.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 34.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 32.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 30.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 26.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 25.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 25.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 24.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 22.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 22.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 22.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 20.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 19.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 17.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 16.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 16.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 16.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 15.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 14.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 14.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 14.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 13.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 13.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 13.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 13.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 13.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 13.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 13.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 13.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 12.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 12.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 12.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 12.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 11.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 11.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 11.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 11.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 10.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 10.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 10.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 10.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 9.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 9.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 9.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 9.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 9.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 9.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 9.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 9.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 8.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 8.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 8.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 8.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 8.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 8.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 8.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 8.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 8.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 8.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 8.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 8.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 8.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 7.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 7.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 7.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 7.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 7.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 7.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 7.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 7.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 7.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 7.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 7.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 7.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 7.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 7.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 7.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 7.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 7.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 6.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 6.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 6.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 6.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 6.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 6.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 6.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 6.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 6.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 6.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 6.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 5.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 5.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 5.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 5.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 5.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 5.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 5.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 5.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 5.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 5.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 5.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 5.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 5.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 5.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 5.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 4.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 4.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 4.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 4.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 4.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 4.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 4.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 4.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 4.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 3.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 3.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 3.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 3.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 3.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 3.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 3.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 3.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 3.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 3.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 3.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 2.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

42.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 42.9
FF:10158-103A5 76 years, female 42.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 32.7
Samples: 4

Max nTPM: 50.5
Min nTPM: 20.2
Sample A Female 30.7
Sample B Female 50.5
Sample C Male 20.2
Sample D Male 29.5
Midbrain
nTPM: 24.1
Samples: 4

Max nTPM: 51.7
Min nTPM: 9.6
Sample A Female 51.7
Sample B Female 9.6
Sample C Male 24.1
Sample D Male 11.0
Periaqueductal gray
nTPM: 16.6
Samples: 3

Max nTPM: 18.6
Min nTPM: 14.8
Sample B Female 16.4
Sample C Male 18.6
Sample D Male 14.8
Superior colliculi
nTPM: 29.4
Samples: 4

Max nTPM: 45.7
Min nTPM: 19.3
Sample A Female 24.8
Sample B Female 45.7
Sample C Male 27.8
Sample D Male 19.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.8
Samples: 4

Max nTPM: 1.0
Min nTPM: 0.4
Sample A Male 0.9
Sample B Male 1.0
Sample C Female 0.4
Sample D Female 0.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
75826672 Antisense, RP_060601_01_D01, Mouse strain C57BL/6J (56 days, male) 0.1
Midbrain
Expression energy: 0.1
75826672 Antisense, RP_060601_01_D01, Mouse strain C57BL/6J (56 days, male) 0.1

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org