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BETA
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  • CBX6
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Brain proteome
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:23.6 nTPM
HPA Brain:126.8 nTPM
GTEx:23.6 nTPM
FANTOM5:102.7 Scaled Tags Per Million
Macaque:100.4 nTPM
Mouse:113.5 nTPM
Rat:149.9 nTPM
Pig:204.1 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 100
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 140
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 119.7
2586 Male, age 75, left hemisphere 182.5
2666 Male, age 74, left hemisphere 133.2
2828 Female, age 72, unknown 129.4
1827 Male, age 72, unknown 126.1
2019 Male, age 18, unknown 123.4
2219 Male, age 76, both hemispheres 119.8
1870 Female, age 42, unknown 98.9
1833 Male, age 53, unknown 97.8
1830 Male, age 51, unknown 93.4
2411 Female, age 72, unknown 92.1
Dorsal raphe nucleus
nTPM: 91.0
2298 Female, age 72, unknown 93.8
2750 Male, age 76, both hemispheres 92.8
1828 Male, age 53, unknown 91.7
2047 Male, age 72, unknown 91.4
2016 Female, age 72, unknown 85.1
Inferior colliculus
nTPM: 105.5
1848 Female, age 42, unknown 108.0
2849 Male, age 72, unknown 107.2
2097 Female, age 72, unknown 104.8
1890 Male, age 53, unknown 102.1
Median raphe nucleus
nTPM: 91.6
2220 Male, age 76, midline 91.6
Periaquaductal grey, anterior
nTPM: 126.8
2502 Female, age 75, unknown 138.6
1795 Male, age 51, unknown 130.9
1947 Male, age 18, unknown 111.0
Periaquaductal grey, dorsal
nTPM: 93.4
1840 Male, age 53, unknown 103.8
2464 Female, age 72, unknown 97.2
1831 Male, age 72, unknown 96.3
2850 Male, age 76, both hemispheres 76.2
Periaquaductal grey, lateral
nTPM: 83.3
2053 Male, age 18, unknown 96.7
2140 Male, age 76, both hemispheres 77.8
2272 Male, age 74, both hemispheres 75.3
Pretectal area
nTPM: 118.1
2007 Male, age 72, unknown 153.2
1816 Male, age 51, unknown 152.9
1817 Female, age 42, unknown 142.4
1944 Female, age 72, unknown 139.3
1815 Male, age 53, unknown 127.6
2407 Male, age 75, both hemispheres 125.0
2667 Female, age 75, unknown 114.3
2825 Male, age 18, unknown 105.0
2224 Female, age 72, unknown 86.1
2316 Male, age 76, right hemisphere 85.0
2273 Male, age 74, both hemispheres 68.3
Red nucleus
nTPM: 104.6
2584 Male, age 75, left hemisphere 150.7
2785 Male, age 18, unknown 123.0
2588 Male, age 74, left hemisphere 121.2
2769 Male, age 72, unknown 105.9
1904 Male, age 53, unknown 100.9
2227 Male, age 72, unknown 98.1
1954 Female, age 42, unknown 96.9
2503 Female, age 72, unknown 95.3
1865 Male, age 51, unknown 95.1
2823 Male, age 76, right hemisphere 92.3
1821 Female, age 72, unknown 88.7
2725 Female, age 75, unknown 86.6
Substantia nigra
nTPM: 107.0
2665 Male, age 74, both hemispheres 140.1
2583 Male, age 75, right hemisphere 127.8
1889 Female, age 72, unknown 120.8
1916 Female, age 42, unknown 115.7
1851 Male, age 51, unknown 113.0
1941 Male, age 53, unknown 111.0
2590 Female, age 75, unknown 96.1
2241 Male, age 72, unknown 85.9
2699 Male, age 18, unknown 84.7
2409 Female, age 72, unknown 75.1
Superior colliculus
nTPM: 119.0
2664 Male, age 75, both hemispheres 173.0
2668 Female, age 75, unknown 139.0
2087 Female, age 72, unknown 130.6
1796 Male, age 53, unknown 126.5
2261 Male, age 18, unknown 122.9
1839 Male, age 51, unknown 106.1
1895 Male, age 76, right hemisphere 103.2
2587 Male, age 74, left hemisphere 98.0
1995 Male, age 72, unknown 96.2
1913 Female, age 42, unknown 94.0
Ventral tegmental area
nTPM: 106.6
2223 Female, age 72, unknown 126.4
2218 Male, age 76, both hemispheres 108.6
1942 Male, age 51, unknown 107.1
1915 Female, age 42, unknown 103.4
2410 Female, age 72, unknown 100.4
2021 Male, age 53, unknown 93.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 23.6
Samples: 183

Max nTPM: 114.6
Min nTPM: 10.8
Std nTPM: 9.9
Median nTPM: 22.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 114.6
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 80.1
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 49.9
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 47.8
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 42.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 37.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 36.6
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 36.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 34.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 34.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 33.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 32.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 32.1
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 31.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 30.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 29.9
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 29.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 29.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 29.5
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 29.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 28.9
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 28.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 28.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 28.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 28.3
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 28.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 28.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 28.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 27.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 27.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 27.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 27.4
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 27.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 27.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 27.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 27.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 27.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 26.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 26.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 26.5
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 26.4
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 25.9
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 25.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 25.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 25.7
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 25.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 25.5
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 25.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 25.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 25.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 25.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 25.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 25.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 25.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 25.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 25.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 25.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 25.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.0
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 24.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 24.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 24.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 24.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 24.8
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 24.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 24.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 24.4
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 24.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 24.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 24.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 24.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 23.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 23.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 23.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 23.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 23.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 23.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 23.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 23.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 23.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 23.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 23.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 23.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 23.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 23.1
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 23.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 23.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 23.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 22.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 22.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 22.8
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 22.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 22.5
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 22.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 22.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 22.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 22.2
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 22.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 22.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 22.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 22.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 22.0
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 21.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 21.8
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 21.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 21.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 21.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 21.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 21.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 21.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 21.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 21.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 20.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 20.9
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 20.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 20.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 20.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 20.5
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 20.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 20.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 20.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 20.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 20.1
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 20.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 20.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 20.0
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 20.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 19.8
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 19.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 19.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 19.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 19.6
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 19.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 19.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 19.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 19.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 19.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 18.9
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 18.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 18.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 18.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 18.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 18.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 18.5
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 18.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 18.4
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 18.2
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 18.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 17.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 17.9
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 17.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 17.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 17.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 17.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 17.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 17.0
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 16.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 16.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 16.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 16.4
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 16.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 16.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 16.0
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 15.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 15.7
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 15.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 15.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 15.2
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 15.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 15.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 14.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 14.6
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 14.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 13.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 13.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 12.9
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 12.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 12.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 12.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 11.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 11.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 11.2
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 10.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

102.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 102.7
FF:10158-103A5 76 years, female 102.7

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.4
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 52.6
Samples: 1

Max nTPM: 52.6
Min nTPM: 52.6
Sample A 52.6
Midbrain
nTPM: 67.7
Samples: 1

Max nTPM: 67.7
Min nTPM: 67.7
Sample A 67.7
Superior colliculi
nTPM: 100.4
Samples: 1

Max nTPM: 100.4
Min nTPM: 100.4
Sample A 100.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

204.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 147.7
Samples: 3

Max nTPM: 167.5
Min nTPM: 127.0
Sample A Female 167.5
Sample B Female 127.0
Sample C Male 148.7
Midbrain
nTPM: 204.1
Samples: 3

Max nTPM: 242.2
Min nTPM: 136.9
Sample B Female 136.9
Sample C Male 242.2
Sample D Male 233.2
Periaqueductal gray
nTPM: 134.0
Samples: 3

Max nTPM: 142.8
Min nTPM: 129.2
Sample B Female 130.1
Sample C Male 142.8
Sample D Male 129.2
Superior colliculi
nTPM: 188.6
Samples: 4

Max nTPM: 222.8
Min nTPM: 130.6
Sample A Female 200.1
Sample B Female 130.6
Sample C Male 201.0
Sample D Male 222.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

113.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 113.5
Samples: 4

Max nTPM: 122.2
Min nTPM: 100.6
Sample A 100.6
Sample B 122.2
Sample C 118.1
Sample D 113.2

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

149.9
Rat sample Sample description nTPM
Midbrain
nTPM: 149.9
Samples: 4

Max nTPM: 160.2
Min nTPM: 133.2
Sample A 147.7
Sample A 160.2
Sample A 158.3
Sample A 133.2

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