MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:24.8 nTPM
HPA Brain:42.3 nTPM
GTEx:24.8 nTPM
FANTOM5:22.4 Scaled Tags Per Million
Pig:16.5 nTPM
Mouse:21.4 nTPM
Allen mouse:4.1 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 42.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 35.7
2019 Male, age 18, unknown 48.8
1830 Male, age 51, unknown 43.6
2586 Male, age 75, left hemisphere 43.6
2411 Female, age 72, unknown 41.8
2219 Male, age 76, both hemispheres 39.7
1833 Male, age 53, unknown 37.8
1870 Female, age 42, unknown 33.0
2828 Female, age 72, unknown 26.3
1827 Male, age 72, unknown 22.8
2666 Male, age 74, left hemisphere 19.6
Dorsal raphe nucleus
nTPM: 23.7
2750 Male, age 76, both hemispheres 34.6
2016 Female, age 72, unknown 23.1
1828 Male, age 53, unknown 22.2
2047 Male, age 72, unknown 20.9
2298 Female, age 72, unknown 17.5
Inferior colliculus
nTPM: 30.7
2849 Male, age 72, unknown 35.0
1848 Female, age 42, unknown 32.8
2097 Female, age 72, unknown 29.8
1890 Male, age 53, unknown 25.2
Median raphe nucleus
nTPM: 23.5
2220 Male, age 76, midline 23.5
Periaquaductal grey, anterior
nTPM: 31.3
2502 Female, age 75, unknown 46.6
1795 Male, age 51, unknown 24.8
1947 Male, age 18, unknown 22.6
Periaquaductal grey, dorsal
nTPM: 25.0
2464 Female, age 72, unknown 34.7
1831 Male, age 72, unknown 25.3
1840 Male, age 53, unknown 23.9
2850 Male, age 76, both hemispheres 16.0
Periaquaductal grey, lateral
nTPM: 26.5
2272 Male, age 74, both hemispheres 32.7
2053 Male, age 18, unknown 25.9
2140 Male, age 76, both hemispheres 20.8
Pretectal area
nTPM: 29.8
2316 Male, age 76, right hemisphere 44.8
2407 Male, age 75, both hemispheres 40.2
2825 Male, age 18, unknown 32.0
2007 Male, age 72, unknown 31.9
1815 Male, age 53, unknown 31.5
2224 Female, age 72, unknown 28.3
1817 Female, age 42, unknown 28.2
1944 Female, age 72, unknown 25.0
2667 Female, age 75, unknown 24.5
2273 Male, age 74, both hemispheres 24.0
1816 Male, age 51, unknown 17.2
Red nucleus
nTPM: 42.3
2785 Male, age 18, unknown 52.6
2503 Female, age 72, unknown 49.4
2769 Male, age 72, unknown 49.4
2227 Male, age 72, unknown 48.8
1865 Male, age 51, unknown 48.1
1904 Male, age 53, unknown 46.0
2588 Male, age 74, left hemisphere 42.5
2584 Male, age 75, left hemisphere 41.9
1954 Female, age 42, unknown 35.7
2823 Male, age 76, right hemisphere 34.1
1821 Female, age 72, unknown 32.4
2725 Female, age 75, unknown 26.2
Substantia nigra
nTPM: 31.1
2583 Male, age 75, right hemisphere 55.4
1851 Male, age 51, unknown 33.4
1941 Male, age 53, unknown 33.3
2409 Female, age 72, unknown 32.4
2590 Female, age 75, unknown 31.2
2699 Male, age 18, unknown 30.4
1889 Female, age 72, unknown 28.7
1916 Female, age 42, unknown 22.9
2665 Male, age 74, both hemispheres 21.9
2241 Male, age 72, unknown 21.4
Superior colliculus
nTPM: 33.5
1913 Female, age 42, unknown 42.4
1839 Male, age 51, unknown 41.0
1995 Male, age 72, unknown 40.6
1895 Male, age 76, right hemisphere 37.6
2668 Female, age 75, unknown 37.2
2664 Male, age 75, both hemispheres 33.5
2587 Male, age 74, left hemisphere 30.4
1796 Male, age 53, unknown 29.3
2087 Female, age 72, unknown 22.1
2261 Male, age 18, unknown 21.1
Ventral tegmental area
nTPM: 30.9
2223 Female, age 72, unknown 49.4
2410 Female, age 72, unknown 31.7
1942 Male, age 51, unknown 28.9
2021 Male, age 53, unknown 28.6
2218 Male, age 76, both hemispheres 24.1
1915 Female, age 42, unknown 22.9

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 24.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 24.8
Samples: 183

Max nTPM: 149.0
Min nTPM: 1.6
Std nTPM: 19.4
Median nTPM: 19.6
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 149.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 129.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 106.8
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 80.6
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 72.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 59.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 55.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 55.3
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 53.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 53.1
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 22.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 22.4
FF:10158-103A5 76 years, female 22.4

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 16.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 5.9
Samples: 4

Max nTPM: 9.4
Min nTPM: 3.7
Sample A Female 9.4
Sample B Female 4.1
Sample C Male 6.5
Sample D Male 3.7
Midbrain
nTPM: 15.4
Samples: 4

Max nTPM: 42.3
Min nTPM: 2.7
Sample A Female 2.7
Sample B Female 5.7
Sample C Male 42.3
Sample D Male 10.9
Periaqueductal gray
nTPM: 6.1
Samples: 3

Max nTPM: 7.0
Min nTPM: 5.4
Sample B Female 5.4
Sample C Male 7.0
Sample D Male 6.0
Superior colliculi
nTPM: 16.5
Samples: 4

Max nTPM: 24.3
Min nTPM: 9.7
Sample A Female 15.1
Sample B Female 9.7
Sample C Male 24.3
Sample D Male 16.9

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 21.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 21.4
Samples: 4

Max nTPM: 22.1
Min nTPM: 20.7
Sample A Male 22.1
Sample B Male 20.7
Sample C Female 22.0
Sample D Female 20.7

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 4.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.1
72128753 Antisense, RP_051017_04_C09, Mouse strain C57BL/6J (56 days, male) 4.9
77869820 Antisense, RP_070212_02_D05, Mouse strain C57BL/6J (56 days, male) 4.5
69407385 Antisense, RP_050414_01_E09, Mouse strain C57BL/6J (56 days, male) 3.0

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