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BETA
  • SUMMARY

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  • MBP
EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

122.255
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:36861.1 nTPM
FANTOM5:24292.6 Scaled Tags Per Million
Macaque:100.7 nTPM
Mouse:5956.5 nTPM
Rat:8020.9 nTPM
Pig:11330.0 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity.

, antibody HPA049222
Pons mean intensity 122.255
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 71.428
Parabrachial nucleus 88.152
Principle sensory trigeminal nucleus 63.376
Locus coeruleus 122.255
Pontine nucleus 56.010
Vestibular nucleus 58.757
Pontine reticular nucleus, oral 59.928
Lateral lemniscus 26.992
Superior paraolivary nucleus 62.675

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36861.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 36861.1
2301 Female, age 85, both hemispheres 55355.1
2188 Female, age 91, both hemispheres 44772.6
2090 Male, age 80, both hemispheres 33904.2
1984 Male, age 76, both hemispheres 13412.4
Dorsal cochlear nucleus
nTPM: 24876.6
2187 Female, age 91, both hemispheres 33971.0
2802 Male, age 74, right hemisphere 26377.9
2378 Male, age 80, both hemispheres 24773.2
2370 Male, age 61, both hemispheres 21966.3
2058 Male, age 76, both hemispheres 17294.6
Dorsal tegmental nucleus
nTPM: 22284.0
2083 Male, age 80, both hemispheres 27854.6
2326 Male, age 74, both hemispheres 22827.5
1936 Male, age 76, left hemisphere 21593.4
2358 Male, age 61, both hemispheres 16860.4
Dorsolateral tegmental area
nTPM: 21653.9
2654 Male, age 80, both hemispheres 30314.5
2751 Female, age 85, both hemispheres 28934.2
2337 Male, age 61, both hemispheres 27112.1
2360 Male, age 74, both hemispheres 11964.2
2141 Male, age 76, both hemispheres 9944.4
Kolliker-Fuse nucleus
nTPM: 27601.2
2793 Female, age 91, left hemisphere 44740.0
2163 Male, age 80, both hemispheres 24947.3
2315 Male, age 76, right hemisphere 13116.1
Lateral lemniscal nuclei
nTPM: 21944.1
2320 Female, age 91, left hemisphere 32001.4
2036 Male, age 80, both hemispheres 22847.0
2169 Male, age 76, both hemispheres 20242.2
2453 Male, age 74, right hemisphere 18042.9
2746 Female, age 85, left hemisphere 16587.3
Lateral parabrachial nucleus
nTPM: 23461.7
2792 Male, age 76, both hemispheres 44230.6
2013 Male, age 80, both hemispheres 21857.9
2790 Male, age 61, both hemispheres 15561.5
2139 Female, age 85, right hemisphere 12196.7
Lateral vestibular nucleus
nTPM: 30871.5
2311 Male, age 80, both hemispheres 37580.9
2184 Male, age 76, both hemispheres 24162.1
Locus coeruleus
nTPM: 9256.8
2720 Male, age 74, both hemispheres 17383.3
2162 Male, age 80, both hemispheres 13511.5
2123 Female, age 91, both hemispheres 8468.4
2317 Female, age 72, unknown 7964.5
2788 Male, age 74, unknown 6742.4
2014 Male, age 55, unknown 6332.3
1980 Male, age 76, both hemispheres 4395.5
Medial parabrachial nucleus
nTPM: 28404.7
2170 Female, age 91, both hemispheres 40066.3
2463 Female, age 85, right hemisphere 27559.9
2854 Male, age 80, both hemispheres 27073.7
2786 Male, age 76, both hemispheres 25931.1
2156 Male, age 61, both hemispheres 21392.6
Medial periolivary nuclei
nTPM: 21936.3
2458 Female, age 91, both hemispheres 35799.5
2081 Male, age 80, both hemispheres 27121.1
2063 Male, age 76, both hemispheres 18023.7
2171 Female, age 85, both hemispheres 14572.2
2791 Male, age 74, right hemisphere 14165.1
Motor facial nucleus
nTPM: 25460.1
2697 Female, age 85, both hemispheres 38244.5
2795 Female, age 91, both hemispheres 30377.0
2126 Male, age 61, both hemispheres 29289.1
2327 Male, age 80, both hemispheres 24847.6
2365 Male, age 74, right hemisphere 15173.2
2062 Male, age 76, both hemispheres 14829.2
Motor trigeminal nucleus
nTPM: 31030.9
2321 Female, age 91, both hemispheres 49034.6
2309 Male, age 76, both hemispheres 32668.2
2335 Male, age 61, both hemispheres 27449.9
2079 Male, age 80, both hemispheres 23528.0
2560 Male, age 74, both hemispheres 22474.0
Nuclei of the trapezoid body
nTPM: 21812.4
2166 Male, age 80, both hemispheres 33114.9
2368 Female, age 91, both hemispheres 28662.0
2159 Male, age 61, both hemispheres 19475.9
1983 Male, age 76, both hemispheres 16756.8
2735 Female, age 85, both hemispheres 11052.2
Nucleus raphe magnus
nTPM: 18226.2
2328 Male, age 80, both hemispheres 26487.0
2459 Female, age 91, both hemispheres 25649.7
2051 Male, age 76, both hemispheres 21987.5
2455 Male, age 74, both hemispheres 15562.3
2172 Female, age 85, both hemispheres 10312.9
2160 Male, age 61, both hemispheres 9357.4
Paramedian reticular nucleus
nTPM: 25117.3
2052 Male, age 76, both hemispheres 36599.8
2057 Male, age 80, both hemispheres 22741.2
2313 Male, age 61, both hemispheres 21910.6
2050 Female, age 85, both hemispheres 19217.5
Pedunculopontine tegmental nucleus
nTPM: 18672.8
2334 Male, age 80, both hemispheres 22298.4
2338 Male, age 61, both hemispheres 21096.5
1921 Female, age 85, both hemispheres 12623.4
Pontine nuclei
nTPM: 21841.1
2319 Female, age 91, both hemispheres 42106.2
2115 Male, age 80, left hemisphere 27365.4
1968 Male, age 76, left hemisphere 22683.7
2454 Male, age 74, left hemisphere 22385.3
2109 Female, age 72, unknown 21187.1
1863 Male, age 55, unknown 17117.1
2787 Female, age 85, both hemispheres 12511.1
2727 Male, age 61, right hemisphere 9372.9
Pontine raphe nucleus
nTPM: 12708.3
2122 Female, age 85, midline 14354.2
2853 Male, age 76, midline 11062.3
Posteroventral cochlear nucleus
nTPM: 34558.2
2135 Female, age 91, both hemispheres 53942.5
2341 Male, age 80, both hemispheres 46389.2
2371 Male, age 61, both hemispheres 30853.3
2070 Male, age 76, both hemispheres 23912.1
2752 Female, age 85, both hemispheres 17694.1
Principal sensory trigeminal nucleus
nTPM: 23011.0
2367 Female, age 91, left hemisphere 35520.7
2324 Male, age 76, both hemispheres 25289.0
2008 Male, age 80, left hemisphere 16250.4
2158 Male, age 61, both hemispheres 14983.8
Reticular pontine nucleus, caudal
nTPM: 26408.3
2457 Female, age 91, both hemispheres 30990.5
2559 Male, age 74, both hemispheres 27366.3
2092 Male, age 76, both hemispheres 25216.7
2332 Male, age 80, right hemisphere 22059.8
Reticular pontine nucleus, oral
nTPM: 24569.9
2366 Female, age 91, both hemispheres 41012.5
2167 Male, age 76, both hemispheres 22833.3
1939 Male, age 80, both hemispheres 22331.5
2012 Female, age 85, both hemispheres 19105.1
2361 Male, age 74, both hemispheres 17567.2
Reticulotegmental nucleus
nTPM: 26427.2
2322 Female, age 91, both hemispheres 33303.3
2333 Male, age 80, both hemispheres 27552.8
2452 Male, age 74, both hemispheres 24253.1
2325 Male, age 76, both hemispheres 20599.7
Spinal trigeminal nucleus, oral
nTPM: 19224.6
2164 Male, age 80, both hemispheres 28084.4
1978 Male, age 76, both hemispheres 16137.2
2737 Female, age 85, both hemispheres 13452.3
Subcoeruleus area
nTPM: 22593.1
2369 Female, age 85, left hemisphere 33101.4
2089 Male, age 76, left hemisphere 23703.1
1958 Male, age 80, both hemispheres 20804.1
2451 Male, age 74, both hemispheres 20532.7
2323 Female, age 91, left hemisphere 14824.1
Superior olive
nTPM: 26433.4
2561 Female, age 91, both hemispheres 36895.8
2020 Male, age 76, both hemispheres 35474.6
2329 Male, age 80, right hemisphere 31450.2
1875 Female, age 85, both hemispheres 15231.5
2364 Male, age 74, right hemisphere 13115.0
Ventral periolivary nuclei
nTPM: 25639.9
2023 Male, age 76, both hemispheres 33275.2
2794 Female, age 91, left hemisphere 33066.8
2165 Male, age 80, both hemispheres 22711.8
2130 Female, age 85, both hemispheres 13505.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 21380.6
2456 Female, age 91, both hemispheres 31272.4
2161 Male, age 80, both hemispheres 24242.7
1959 Male, age 76, both hemispheres 22105.5
2840 Female, age 85, both hemispheres 20965.6
2359 Male, age 61, both hemispheres 14893.2
2449 Male, age 74, both hemispheres 14804.2

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

24292.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 23437.8
FF:10182-103D2 60 years, female 27176.2
FF:10165-103B3 76 years, female 19699.4
Pons
Scaled Tags Per Million: 24292.6
FF:10033-101E6 18-54 years, mixed 24292.6

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.7
Macaque sample Sample description nTPM
Pons
nTPM: 100.7
Samples: 2

Max nTPM: 125.3
Min nTPM: 76.1
Sample A 125.3
Sample B 76.1

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

11330.0
Pig sample Sample description nTPM
Pons
nTPM: 11330.0
Samples: 3

Max nTPM: 17287.8
Min nTPM: 7958.6
Sample A Female 7958.6
Sample B Female 8743.5
Sample C Male 17287.8

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

5956.5
Mouse sample Sample description nTPM
Pons
nTPM: 5956.6
Samples: 4

Max nTPM: 6341.9
Min nTPM: 5350.8
Sample A 6329.6
Sample B 5350.8
Sample C 6341.9
Sample D 5803.9

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

8020.9
Rat sample Sample description nTPM
Pons
nTPM: 8020.9
Samples: 4

Max nTPM: 8634.6
Min nTPM: 6827.2
Sample A 8020.1
Sample A 6827.2
Sample A 8601.8
Sample A 8634.6

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