MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:35.4 nTPM
HPA Brain:49.4 nTPM
GTEx:35.4 nTPM
FANTOM5:2.7 Scaled Tags Per Million
Pig:41.3 nTPM
Mouse:75.0 nTPM
Allen mouse:9.8 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 49.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 28.7
2219 Male, age 76, both hemispheres 35.3
1827 Male, age 72, unknown 34.6
2666 Male, age 74, left hemisphere 34.5
2411 Female, age 72, unknown 30.6
2586 Male, age 75, left hemisphere 30.2
2828 Female, age 72, unknown 29.7
2019 Male, age 18, unknown 24.3
1833 Male, age 53, unknown 23.3
1870 Female, age 42, unknown 22.4
1830 Male, age 51, unknown 21.9
Dorsal raphe nucleus
nTPM: 34.0
2298 Female, age 72, unknown 40.7
2047 Male, age 72, unknown 40.3
2750 Male, age 76, both hemispheres 38.4
1828 Male, age 53, unknown 30.3
2016 Female, age 72, unknown 20.4
Inferior colliculus
nTPM: 22.2
2097 Female, age 72, unknown 23.2
2849 Male, age 72, unknown 22.3
1848 Female, age 42, unknown 22.2
1890 Male, age 53, unknown 21.3
Median raphe nucleus
nTPM: 49.4
2220 Male, age 76, midline 49.4
Periaquaductal grey, anterior
nTPM: 37.5
2502 Female, age 75, unknown 47.0
1947 Male, age 18, unknown 33.1
1795 Male, age 51, unknown 32.6
Periaquaductal grey, dorsal
nTPM: 24.8
1831 Male, age 72, unknown 25.6
2850 Male, age 76, both hemispheres 25.1
1840 Male, age 53, unknown 24.9
2464 Female, age 72, unknown 23.5
Periaquaductal grey, lateral
nTPM: 18.8
2140 Male, age 76, both hemispheres 21.8
2053 Male, age 18, unknown 21.3
2272 Male, age 74, both hemispheres 13.4
Pretectal area
nTPM: 28.0
1816 Male, age 51, unknown 41.5
2007 Male, age 72, unknown 37.4
2667 Female, age 75, unknown 34.2
1817 Female, age 42, unknown 33.5
1944 Female, age 72, unknown 33.0
1815 Male, age 53, unknown 28.5
2825 Male, age 18, unknown 27.0
2224 Female, age 72, unknown 26.2
2316 Male, age 76, right hemisphere 18.7
2407 Male, age 75, both hemispheres 15.5
2273 Male, age 74, both hemispheres 12.6
Red nucleus
nTPM: 20.4
2584 Male, age 75, left hemisphere 26.5
2588 Male, age 74, left hemisphere 23.6
2785 Male, age 18, unknown 22.8
1821 Female, age 72, unknown 22.0
1954 Female, age 42, unknown 21.1
2769 Male, age 72, unknown 20.4
2823 Male, age 76, right hemisphere 20.3
2227 Male, age 72, unknown 20.2
1904 Male, age 53, unknown 19.6
2503 Female, age 72, unknown 19.3
1865 Male, age 51, unknown 19.1
2725 Female, age 75, unknown 9.3
Substantia nigra
nTPM: 31.8
2665 Male, age 74, both hemispheres 52.2
1916 Female, age 42, unknown 49.9
1941 Male, age 53, unknown 38.3
1851 Male, age 51, unknown 34.1
1889 Female, age 72, unknown 29.4
2699 Male, age 18, unknown 27.1
2241 Male, age 72, unknown 25.8
2583 Male, age 75, right hemisphere 24.3
2409 Female, age 72, unknown 24.0
2590 Female, age 75, unknown 12.7
Superior colliculus
nTPM: 29.5
2668 Female, age 75, unknown 75.7
2087 Female, age 72, unknown 31.9
1895 Male, age 76, right hemisphere 29.2
2664 Male, age 75, both hemispheres 29.2
1796 Male, age 53, unknown 28.6
2261 Male, age 18, unknown 28.1
1839 Male, age 51, unknown 24.1
2587 Male, age 74, left hemisphere 18.2
1913 Female, age 42, unknown 16.9
1995 Male, age 72, unknown 13.1
Ventral tegmental area
nTPM: 32.9
2218 Male, age 76, both hemispheres 42.2
1915 Female, age 42, unknown 35.7
2410 Female, age 72, unknown 34.1
1942 Male, age 51, unknown 29.9
2021 Male, age 53, unknown 29.9
2223 Female, age 72, unknown 25.6

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 35.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 35.4
Samples: 183

Max nTPM: 94.2
Min nTPM: 2.8
Std nTPM: 21.7
Median nTPM: 30.9
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 94.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 94.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 92.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 91.3
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 86.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 86.3
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 85.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 80.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 76.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 76.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 73.6
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 2.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2.7
FF:10158-103A5 76 years, female 2.7

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 41.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 34.4
Samples: 4

Max nTPM: 52.7
Min nTPM: 10.9
Sample A Female 51.0
Sample B Female 22.8
Sample C Male 52.7
Sample D Male 10.9
Midbrain
nTPM: 38.3
Samples: 4

Max nTPM: 70.3
Min nTPM: 4.5
Sample A Female 4.5
Sample B Female 25.7
Sample C Male 70.3
Sample D Male 52.7
Periaqueductal gray
nTPM: 26.0
Samples: 3

Max nTPM: 36.5
Min nTPM: 19.2
Sample B Female 22.3
Sample C Male 36.5
Sample D Male 19.2
Superior colliculi
nTPM: 41.3
Samples: 4

Max nTPM: 64.3
Min nTPM: 21.7
Sample A Female 37.8
Sample B Female 21.7
Sample C Male 64.3
Sample D Male 41.2

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 75.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 75.0
Samples: 4

Max nTPM: 77.0
Min nTPM: 73.1
Sample A Male 77.0
Sample B Male 74.5
Sample C Female 75.5
Sample D Female 73.1

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 9.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.8
71380550 Antisense, RP_050419_04_G06, Mouse strain C57BL/6J (56 days, male) 10.4
76097701 Antisense, RP_060620_02_A06, Mouse strain C57BL/6J (56 days, male) 9.2

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