BETA
MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
HPA Brain:0.3 nTPM
Macaque:5.6 nTPM
Rat:0.4 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 10
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 10
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 0.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 0.2
2828 Female, age 72, unknown 0.4
2019 Male, age 18, unknown 0.3
1827 Male, age 72, unknown 0.2
1830 Male, age 51, unknown 0.2
2219 Male, age 76, both hemispheres 0.2
2411 Female, age 72, unknown 0.2
2586 Male, age 75, left hemisphere 0.2
1833 Male, age 53, unknown 0.0
1870 Female, age 42, unknown 0.0
2666 Male, age 74, left hemisphere 0.0
Dorsal raphe nucleus
nTPM: 0.1
2750 Male, age 76, both hemispheres 0.2
1828 Male, age 53, unknown 0.1
2016 Female, age 72, unknown 0.0
2047 Male, age 72, unknown 0.0
2298 Female, age 72, unknown 0.0
Inferior colliculus
nTPM: 0.2
2097 Female, age 72, unknown 0.3
1848 Female, age 42, unknown 0.1
1890 Male, age 53, unknown 0.1
2849 Male, age 72, unknown 0.1
Median raphe nucleus
nTPM: 0.2
2220 Male, age 76, midline 0.2
Periaquaductal grey, anterior
nTPM: 0.1
1947 Male, age 18, unknown 0.1
2502 Female, age 75, unknown 0.1
1795 Male, age 51, unknown 0.0
Periaquaductal grey, dorsal
nTPM: 0.2
1840 Male, age 53, unknown 0.3
2464 Female, age 72, unknown 0.2
2850 Male, age 76, both hemispheres 0.2
1831 Male, age 72, unknown 0.1
Periaquaductal grey, lateral
nTPM: 0.2
2053 Male, age 18, unknown 0.3
2140 Male, age 76, both hemispheres 0.2
2272 Male, age 74, both hemispheres 0.1
Pretectal area
nTPM: 0.2
1815 Male, age 53, unknown 0.3
2007 Male, age 72, unknown 0.3
2407 Male, age 75, both hemispheres 0.3
1816 Male, age 51, unknown 0.2
1817 Female, age 42, unknown 0.2
1944 Female, age 72, unknown 0.2
2224 Female, age 72, unknown 0.2
2316 Male, age 76, right hemisphere 0.2
2667 Female, age 75, unknown 0.1
2273 Male, age 74, both hemispheres 0.0
2825 Male, age 18, unknown 0.0
Red nucleus
nTPM: 0.1
1821 Female, age 72, unknown 0.2
2584 Male, age 75, left hemisphere 0.2
2823 Male, age 76, right hemisphere 0.2
1904 Male, age 53, unknown 0.1
2725 Female, age 75, unknown 0.1
2769 Male, age 72, unknown 0.1
2785 Male, age 18, unknown 0.1
1865 Male, age 51, unknown 0.0
1954 Female, age 42, unknown 0.0
2227 Male, age 72, unknown 0.0
2503 Female, age 72, unknown 0.0
2588 Male, age 74, left hemisphere 0.0
Substantia nigra
nTPM: 0.3
1916 Female, age 42, unknown 0.7
2241 Male, age 72, unknown 0.7
1851 Male, age 51, unknown 0.5
1889 Female, age 72, unknown 0.4
1941 Male, age 53, unknown 0.2
2583 Male, age 75, right hemisphere 0.1
2590 Female, age 75, unknown 0.1
2699 Male, age 18, unknown 0.1
2409 Female, age 72, unknown 0.0
2665 Male, age 74, both hemispheres 0.0
Superior colliculus
nTPM: 0.2
2087 Female, age 72, unknown 0.5
1895 Male, age 76, right hemisphere 0.3
1796 Male, age 53, unknown 0.2
2261 Male, age 18, unknown 0.2
1839 Male, age 51, unknown 0.1
2587 Male, age 74, left hemisphere 0.1
2664 Male, age 75, both hemispheres 0.1
2668 Female, age 75, unknown 0.1
1913 Female, age 42, unknown 0.0
1995 Male, age 72, unknown 0.0
Ventral tegmental area
nTPM: 0.3
1915 Female, age 42, unknown 0.5
2410 Female, age 72, unknown 0.5
2218 Male, age 76, both hemispheres 0.3
2021 Male, age 53, unknown 0.2
1942 Male, age 51, unknown 0.1
2223 Female, age 72, unknown 0.0

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi 5.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 4.4
Samples: 1

Max nTPM: 4.4
Min nTPM: 4.4
Sample A 4.4
Midbrain
nTPM: 3.7
Samples: 1

Max nTPM: 3.7
Min nTPM: 3.7
Sample A 3.7
Superior colliculi
nTPM: 5.6
Samples: 1

Max nTPM: 5.6
Min nTPM: 5.6
Sample A 5.6

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi 0.4
Rat sample Sample description nTPM
Midbrain
nTPM: 0.4
Samples: 4

Max nTPM: 0.8
Min nTPM: 0.0
Sample A 0.4
Sample A 0.5
Sample A 0.8
Sample A 0.0

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