On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
9.2
nTPM
HPA:
9.2
nTPM
HPA Brain:
25.6
nTPM
HPA PFC Brain:
33.3
nTPM
FANTOM5:
35.5
Scaled Tags Per Million
Mouse:
24.4
nTPM
Pig:
5.5
nTPM
CEREBRAL CORTEX - Annotated protein expression
Pending normal tissue analysis
CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity
ND
Sample
Intensity
Cerebral cortex_01
ND
Cerebral cortex_02
998
Cerebral cortex_03
957
Cerebral cortex_04
ND
Cerebral cortex_05
ND
Cerebral cortex_06
ND
Cerebral cortex_07
906
Cerebral cortex_08
ND
Cerebral cortex_09
ND
Cerebral cortex_10
1091
Cerebral cortex_11
ND
Cerebral cortex_12
ND
Cerebral cortex_13
ND
Cerebral cortex_14
ND
Cerebral cortex_15
2188
Cerebral cortex_16
ND
Cerebral cortex_17
ND
Cerebral cortex_18
ND
Cerebral cortex_19
1296
Cerebral cortex_20
ND
Cerebral cortex_21
ND
Cerebral cortex_22
ND
Cerebral cortex_23
ND
Cerebral cortex_24
ND
Cerebral cortex_25
ND
Cerebral cortex_26
ND
Cerebral cortex_27
ND
Cerebral cortex_28
ND
Cerebral cortex_29
ND
Cerebral cortex_30
ND
Cerebral cortex_31
ND
Cerebral cortex_32
ND
Cerebral cortex_33
ND
Cerebral cortex_34
ND
Cerebral cortex_35
ND
Cerebral cortex_36
ND
Cerebral cortex_37
ND
Cerebral cortex_38
ND
CEREBRAL CORTEX - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
9.2
Male, age 5
Cerebral cortex sample 48 nTPM: 10.7
Female, age 40
Cerebral cortex sample 105 nTPM: 6.6
Cell types%
Neuronal cells:
35
Glial cells and endothelial cells:
65
Male, age 70
Cerebral cortex sample 106 nTPM: 10.2
Cell types%
Neuronal cells:
35
Glial cells and endothelial cells:
65
CEREBRAL CORTEX - HPA Brain Stereo-seq
CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
5.5
Pig sample
Sample description
nTPM
Occipital cortex nTPM: 4.8
Samples: 4
Max nTPM: 6.4
Min nTPM: 2.8
Sample A
Female
6.0
Sample B
Female
2.8
Sample C
Male
6.4
Sample D
Male
4.1
Retrosplenial cortex nTPM: 4.5
Samples: 4
Max nTPM: 5.4
Min nTPM: 3.7
Sample A
Female
4.8
Sample B
Female
3.7
Sample C
Male
5.4
Sample D
Male
4.2
Cingulate cortex nTPM: 4.8
Samples: 4
Max nTPM: 6.3
Min nTPM: 3.1
Sample A
Female
5.5
Sample B
Female
3.1
Sample C
Male
6.3
Sample D
Male
4.3
Insular cortex nTPM: 4.3
Samples: 4
Max nTPM: 5.5
Min nTPM: 3.0
Sample A
Female
4.8
Sample B
Female
3.0
Sample C
Male
5.5
Sample D
Male
4.0
Motor cortex nTPM: 4.9
Samples: 4
Max nTPM: 6.0
Min nTPM: 4.4
Sample A
Female
4.7
Sample B
Female
4.6
Sample C
Male
6.0
Sample D
Male
4.4
Prefrontal cortex nTPM: 4.6
Samples: 4
Max nTPM: 4.8
Min nTPM: 4.0
Sample A
Female
4.0
Sample B
Female
4.7
Sample C
Male
4.8
Sample D
Male
4.7
Somatosensory cortex nTPM: 5.5
Samples: 3
Max nTPM: 6.5
Min nTPM: 4.1
Sample B
Female
4.1
Sample C
Male
6.5
Sample D
Male
5.9
Temporal cortex nTPM: 4.4
Samples: 3
Max nTPM: 4.8
Min nTPM: 3.8
Sample A
Female
4.8
Sample B
Female
3.8
Sample D
Male
4.6
CEREBRAL CORTEX - Mouse RNA-seqi
RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
24.4
Mouse sample
Sample description
nTPM
Motor and prefrontal cortex nTPM: 20.5
Samples: 4
Max nTPM: 22.0
Min nTPM: 19.4
Sample A
20.4
Sample B
19.4
Sample C
22.0
Sample D
20.4
Retrosplenial and cingulate cortex nTPM: 23.7
Samples: 3
Max nTPM: 24.3
Min nTPM: 23.0
Sample A
24.3
Sample B
23.0
Sample C
23.9
Somatosensory cortex nTPM: 24.5
Samples: 4
Max nTPM: 25.4
Min nTPM: 23.3
Sample A
23.3
Sample B
24.7
Sample C
24.4
Sample D
25.4
Visual cortex nTPM: 23.1
Samples: 4
Max nTPM: 24.4
Min nTPM: 22.3
Sample A
24.4
Sample B
22.3
Sample C
23.3
Sample D
22.5
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