Throughout life, blood cells are continuously formed in the bone marrow, a process known as hematopoiesis. Hematopoiesis relies on several different mediators, and defects in this system may cause severe pathological conditions...Read more
The fallopian tube mucosal layer is a simple columnar epithelium composed of secretory and ciliated epithelial cells, in order to provide the necessary environment for fertilization of the egg cell...Read more
Approximately 11% of the human proteins are defined as missing proteins. These proteins lack experimental data on the protein level. In an investigation led by Sjöstedt et al, an integrated omics approach was applied to explore and identify missing proteins...Read more
Located on top of the kidneys like two tiny caps, the adrenal glands play a fundamental role in the endocrine system. We have previously described the human adrenal gland proteome and now it is time to shed light on proteins specific for the medullary compartment of the adrenal gland. These proteins are essential for the synthesis of two major stress coping hormones - adrenaline and noradrenaline...Read more
Previous news articles featured the history and technology behind two powerful tools for visualizing proteins in tissues: immunohistochemistry and microscopy. These tools are applied to investigate and answer a wide range of questions, both in healthcare and research. This article focuses on two applications related to lung cancer: diagnostics in clinical pathology and discovery of genes associated with prognosis...Read more
March 28, 2019 - March 29, 2019
On March 29th, 2019, Mathias Uhlén will give a keynote on "The Human Protein Atlas - implications for human biology, drug development and precision medicine" at the International Rouen P2M Symposium on Precision Medicine "Pathways to Precision Medicine".