News Articles


TH, DBH and PNMT play pivotal roles in catecholamine production in the adrenal medulla

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Located on top of the kidneys like two tiny caps, the adrenal glands play a fundamental role in the endocrine system. We have previously described the human adrenal gland proteome and now it is time to shed light on proteins specific for the medullary compartment of the adrenal gland. These proteins are essential for the synthesis of two major stress coping hormones - adrenaline and noradrenaline...Read more


Immunohistochemistry in lung cancer diagnostics and research

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Previous news articles featured the history and technology behind two powerful tools for visualizing proteins in tissues: immunohistochemistry and microscopy. These tools are applied to investigate and answer a wide range of questions, both in healthcare and research. This article focuses on two applications related to lung cancer: diagnostics in clinical pathology and discovery of genes associated with prognosis...Read more


Immunohistochemistry - an invaluable tool for research and healthcare

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Immunohistochemistry was first described by Coons et al. in the beginning of the 1940s, where the authors used fluorescein-labeled antibodies to visualize bacterial antigens in infected tissues. Today, IHC plays a pivotal role in diagnostics and serves as an essential tool in research...Read more


57 genes associated with prognostic outcome in testis cancer

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Testicular cancer is a rare type of cancer. Most testis cancers are curable, even at an advanced stage. The cancer can be divided into essentially two categories: Seminoma and Non-seminomatous germ cell tumors. Based on transcriptomics data and clinical metadata we have been able to determine 57 genes associated with either favorable or unfavorable prognosis in testis cancer...Read more


792 Genes Associated with Prognosis in Head and Neck Cancer

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Head and neck cancer arises in the epithelium of the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx. By using a systems level approach to analyze the head and neck cancer proteome based on clinical metadata and genome-wide transcriptomics data, 792 genes were found to be associated with prognostic outcome...Read more


Upcoming Events


The 13th International Conference on Genomics

October 24, 2018 - October 28, 2018

Mathias Uhlen will present "The creation of a mammalian protein brain atlas" at the 13th International Conference on Genomics taking place in Shenzhen, China. His talk is scheduled at 15.20 on October 26.
Programme

Biomarkers – methods and technologies

October 25, 2018 - October 26, 2018

Dr. Jochen Schwenk will give a talk on "Affinity-based assays for biomarkers of the plasma proteome", at the 14th Annual Workshop of Biofilms - Research Center for Biointerfaces, which focuses on Biomarkers - methods and technology, held at Malmö University.
Programme