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BETA
  • SUMMARY

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  • BRAIN

  • SINGLE CELL

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  • SPAG9
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:52.1 nTPM
HPA Brain:128.8 nTPM
GTEx:52.1 nTPM
FANTOM5:370.3 Scaled Tags Per Million
Macaque:105.7 nTPM
Mouse:147.3 nTPM
Rat:95.6 nTPM
Pig:109.4 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 270
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 700
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

128.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 124.0
2019 Male, age 18, unknown 134.6
2411 Female, age 72, unknown 132.7
1870 Female, age 42, unknown 130.8
2586 Male, age 75, left hemisphere 128.8
1827 Male, age 72, unknown 127.0
2828 Female, age 72, unknown 122.7
1830 Male, age 51, unknown 120.2
2666 Male, age 74, left hemisphere 118.5
1833 Male, age 53, unknown 117.0
2219 Male, age 76, both hemispheres 107.5
Dorsal raphe nucleus
nTPM: 115.0
2750 Male, age 76, both hemispheres 124.9
2016 Female, age 72, unknown 118.1
1828 Male, age 53, unknown 116.5
2298 Female, age 72, unknown 109.3
2047 Male, age 72, unknown 106.0
Inferior colliculus
nTPM: 112.6
1890 Male, age 53, unknown 117.6
2097 Female, age 72, unknown 115.4
1848 Female, age 42, unknown 111.6
2849 Male, age 72, unknown 106.0
Median raphe nucleus
nTPM: 112.8
2220 Male, age 76, midline 112.8
Periaquaductal grey, anterior
nTPM: 120.9
2502 Female, age 75, unknown 132.0
1947 Male, age 18, unknown 120.1
1795 Male, age 51, unknown 110.6
Periaquaductal grey, dorsal
nTPM: 110.3
1831 Male, age 72, unknown 118.4
2464 Female, age 72, unknown 115.5
2850 Male, age 76, both hemispheres 108.3
1840 Male, age 53, unknown 99.2
Periaquaductal grey, lateral
nTPM: 106.9
2053 Male, age 18, unknown 115.9
2140 Male, age 76, both hemispheres 103.4
2272 Male, age 74, both hemispheres 101.3
Pretectal area
nTPM: 125.1
1816 Male, age 51, unknown 143.1
1815 Male, age 53, unknown 136.7
2007 Male, age 72, unknown 135.7
1944 Female, age 72, unknown 134.0
1817 Female, age 42, unknown 129.8
2273 Male, age 74, both hemispheres 129.4
2316 Male, age 76, right hemisphere 115.4
2407 Male, age 75, both hemispheres 115.4
2825 Male, age 18, unknown 113.5
2667 Female, age 75, unknown 112.3
2224 Female, age 72, unknown 110.7
Red nucleus
nTPM: 128.8
1865 Male, age 51, unknown 148.8
1821 Female, age 72, unknown 145.6
1904 Male, age 53, unknown 140.1
2503 Female, age 72, unknown 137.3
2785 Male, age 18, unknown 136.8
1954 Female, age 42, unknown 126.9
2588 Male, age 74, left hemisphere 126.4
2769 Male, age 72, unknown 124.0
2227 Male, age 72, unknown 123.3
2823 Male, age 76, right hemisphere 117.8
2725 Female, age 75, unknown 112.4
2584 Male, age 75, left hemisphere 106.5
Substantia nigra
nTPM: 115.3
1889 Female, age 72, unknown 130.2
2409 Female, age 72, unknown 126.9
2583 Male, age 75, right hemisphere 119.9
2590 Female, age 75, unknown 119.1
1941 Male, age 53, unknown 117.7
2241 Male, age 72, unknown 113.0
1851 Male, age 51, unknown 112.8
2665 Male, age 74, both hemispheres 108.5
1916 Female, age 42, unknown 104.0
2699 Male, age 18, unknown 101.1
Superior colliculus
nTPM: 127.9
1913 Female, age 42, unknown 147.2
2668 Female, age 75, unknown 142.3
1995 Male, age 72, unknown 133.2
2587 Male, age 74, left hemisphere 130.5
2261 Male, age 18, unknown 126.7
2664 Male, age 75, both hemispheres 126.0
2087 Female, age 72, unknown 121.6
1895 Male, age 76, right hemisphere 120.6
1796 Male, age 53, unknown 119.6
1839 Male, age 51, unknown 111.3
Ventral tegmental area
nTPM: 110.6
2410 Female, age 72, unknown 119.5
2223 Female, age 72, unknown 118.3
1942 Male, age 51, unknown 108.6
2218 Male, age 76, both hemispheres 107.1
2021 Male, age 53, unknown 106.2
1915 Female, age 42, unknown 103.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 52.1
Samples: 183

Max nTPM: 151.0
Min nTPM: 19.6
Std nTPM: 17.7
Median nTPM: 48.8
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 151.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 108.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 99.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 95.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 92.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 91.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 88.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 87.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 85.7
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 81.3
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 81.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 80.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 79.8
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 78.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 76.3
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 75.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 75.5
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 75.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 74.7
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 73.5
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 72.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 71.7
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 71.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 71.5
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 71.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 71.2
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 70.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 70.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 70.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 68.5
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 68.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 68.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 67.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 66.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 66.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 66.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 66.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 65.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 65.5
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 64.8
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 63.7
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 62.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 61.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 61.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 61.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 61.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 60.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 60.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 60.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 59.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 59.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 59.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 59.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 58.0
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 57.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 57.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 56.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 56.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 56.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 55.5
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 55.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 54.5
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 54.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 54.2
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 54.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 53.1
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 53.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 52.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 52.7
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 52.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 52.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 52.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.4
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 52.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 51.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 51.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 51.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 51.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 51.5
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 51.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 50.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 50.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 50.2
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 50.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 50.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 49.5
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 49.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 49.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 48.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 48.6
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 48.2
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 48.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 47.8
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 47.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 47.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 47.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 47.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 46.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 46.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 46.5
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 46.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 45.9
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 45.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 45.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 45.5
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 45.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 45.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 44.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 44.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 44.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 44.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 44.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 44.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 44.1
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 44.0
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 44.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 43.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 43.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 43.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 42.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 42.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 42.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 42.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 42.0
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 42.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 41.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 41.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 41.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.2
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 40.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 40.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 40.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 40.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 40.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 39.1
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 38.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 38.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 38.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 38.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 37.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 37.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 37.2
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 36.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 36.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 36.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 36.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 35.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 35.6
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 35.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 35.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 35.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 35.1
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 34.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 34.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 34.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 33.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 33.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 33.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 33.6
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 33.6
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 32.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 32.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 32.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 32.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 32.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 32.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.0
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 31.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 31.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 31.6
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 31.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 31.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 30.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 29.7
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 28.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 27.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 24.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 23.0
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 19.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

370.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 370.3
FF:10158-103A5 76 years, female 370.3

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

105.7
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 105.7
Samples: 1

Max nTPM: 105.7
Min nTPM: 105.7
Sample A 105.7
Midbrain
nTPM: 79.1
Samples: 1

Max nTPM: 79.1
Min nTPM: 79.1
Sample A 79.1
Superior colliculi
nTPM: 84.2
Samples: 1

Max nTPM: 84.2
Min nTPM: 84.2
Sample A 84.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 92.3
Samples: 3

Max nTPM: 96.6
Min nTPM: 86.8
Sample A Female 96.6
Sample B Female 86.8
Sample C Male 93.5
Midbrain
nTPM: 109.3
Samples: 3

Max nTPM: 112.8
Min nTPM: 105.9
Sample B Female 109.3
Sample C Male 112.8
Sample D Male 105.9
Periaqueductal gray
nTPM: 96.1
Samples: 3

Max nTPM: 104.0
Min nTPM: 91.3
Sample B Female 104.0
Sample C Male 93.0
Sample D Male 91.3
Superior colliculi
nTPM: 99.1
Samples: 4

Max nTPM: 109.0
Min nTPM: 74.6
Sample A Female 106.0
Sample B Female 74.6
Sample C Male 109.0
Sample D Male 106.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

147.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 147.3
Samples: 4

Max nTPM: 158.6
Min nTPM: 138.2
Sample A 138.2
Sample B 139.5
Sample C 152.7
Sample D 158.6

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.6
Rat sample Sample description nTPM
Midbrain
nTPM: 95.6
Samples: 4

Max nTPM: 98.3
Min nTPM: 93.3
Sample A 93.3
Sample A 94.9
Sample A 96.0
Sample A 98.3

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