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BETA
  • SUMMARY

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  • BRAIN

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  • SLC44A1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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VALIDATION
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Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:116.2 nTPM
HPA Brain:277.4 nTPM
GTEx:116.2 nTPM
FANTOM5:722.2 Scaled Tags Per Million
Macaque:254.2 nTPM
Mouse:72.9 nTPM
Rat:107.4 nTPM
Pig:156.6 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 310
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 4820
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

277.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 215.5
2411 Female, age 72, unknown 288.3
1870 Female, age 42, unknown 273.0
1830 Male, age 51, unknown 269.9
1833 Male, age 53, unknown 258.9
2019 Male, age 18, unknown 256.8
2828 Female, age 72, unknown 201.5
2666 Male, age 74, left hemisphere 163.9
2219 Male, age 76, both hemispheres 158.1
1827 Male, age 72, unknown 153.7
2586 Male, age 75, left hemisphere 131.3
Dorsal raphe nucleus
nTPM: 179.5
2750 Male, age 76, both hemispheres 300.8
2016 Female, age 72, unknown 194.4
1828 Male, age 53, unknown 162.9
2298 Female, age 72, unknown 123.7
2047 Male, age 72, unknown 115.7
Inferior colliculus
nTPM: 146.5
1890 Male, age 53, unknown 160.5
1848 Female, age 42, unknown 148.6
2097 Female, age 72, unknown 141.1
2849 Male, age 72, unknown 135.9
Median raphe nucleus
nTPM: 129.9
2220 Male, age 76, midline 129.9
Periaquaductal grey, anterior
nTPM: 140.1
2502 Female, age 75, unknown 167.4
1947 Male, age 18, unknown 148.8
1795 Male, age 51, unknown 104.0
Periaquaductal grey, dorsal
nTPM: 126.3
2464 Female, age 72, unknown 180.9
2850 Male, age 76, both hemispheres 123.6
1831 Male, age 72, unknown 116.8
1840 Male, age 53, unknown 83.9
Periaquaductal grey, lateral
nTPM: 139.3
2272 Male, age 74, both hemispheres 155.6
2053 Male, age 18, unknown 141.7
2140 Male, age 76, both hemispheres 120.6
Pretectal area
nTPM: 144.7
2316 Male, age 76, right hemisphere 206.9
1815 Male, age 53, unknown 198.9
2273 Male, age 74, both hemispheres 156.8
1817 Female, age 42, unknown 154.4
2007 Male, age 72, unknown 152.3
2825 Male, age 18, unknown 147.1
2407 Male, age 75, both hemispheres 133.2
2667 Female, age 75, unknown 132.0
2224 Female, age 72, unknown 127.2
1944 Female, age 72, unknown 92.6
1816 Male, age 51, unknown 90.8
Red nucleus
nTPM: 277.4
1865 Male, age 51, unknown 348.4
1821 Female, age 72, unknown 345.3
1904 Male, age 53, unknown 333.8
2769 Male, age 72, unknown 300.1
2227 Male, age 72, unknown 297.4
2503 Female, age 72, unknown 290.9
2785 Male, age 18, unknown 287.2
2823 Male, age 76, right hemisphere 286.2
1954 Female, age 42, unknown 279.4
2588 Male, age 74, left hemisphere 218.7
2725 Female, age 75, unknown 195.4
2584 Male, age 75, left hemisphere 146.3
Substantia nigra
nTPM: 167.7
2409 Female, age 72, unknown 235.8
1851 Male, age 51, unknown 199.0
2590 Female, age 75, unknown 185.5
1889 Female, age 72, unknown 179.0
2241 Male, age 72, unknown 170.6
2699 Male, age 18, unknown 161.2
2583 Male, age 75, right hemisphere 153.3
1941 Male, age 53, unknown 144.9
1916 Female, age 42, unknown 133.0
2665 Male, age 74, both hemispheres 114.5
Superior colliculus
nTPM: 182.2
1913 Female, age 42, unknown 285.0
1995 Male, age 72, unknown 273.9
1895 Male, age 76, right hemisphere 218.7
2587 Male, age 74, left hemisphere 211.0
1839 Male, age 51, unknown 190.2
2668 Female, age 75, unknown 183.1
1796 Male, age 53, unknown 134.7
2261 Male, age 18, unknown 114.2
2087 Female, age 72, unknown 113.1
2664 Male, age 75, both hemispheres 97.7
Ventral tegmental area
nTPM: 187.8
2410 Female, age 72, unknown 257.6
2223 Female, age 72, unknown 231.1
1942 Male, age 51, unknown 165.8
2021 Male, age 53, unknown 165.3
1915 Female, age 42, unknown 164.0
2218 Male, age 76, both hemispheres 142.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

116.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 116.2
Samples: 183

Max nTPM: 330.4
Min nTPM: 10.1
Std nTPM: 50.0
Median nTPM: 106.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 330.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 275.8
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 275.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 270.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 243.3
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 235.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 223.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 212.9
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 210.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 209.1
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 209.1
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 206.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 201.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 199.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 199.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 195.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 190.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 186.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 185.1
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 184.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 177.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 173.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 172.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 172.2
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 172.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 168.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 165.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 164.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 163.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 160.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 158.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 156.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 154.3
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 153.8
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 153.6
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 152.4
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 152.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 151.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 149.5
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 148.6
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 145.9
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 143.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 142.8
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 139.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 137.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 136.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 135.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 135.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 134.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 134.4
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 133.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 132.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 131.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 131.1
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 130.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 129.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 129.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 128.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 128.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 126.3
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 124.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 123.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 123.2
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 122.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 122.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 122.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 122.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 121.8
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 119.9
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 119.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 118.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 118.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 117.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 117.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 117.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 115.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 114.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 112.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 112.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 112.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 110.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 110.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 110.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 110.1
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 109.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 108.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 108.5
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 108.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 107.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 107.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 106.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 106.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 105.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 105.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 104.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 104.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 103.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 103.5
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 103.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 102.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 102.6
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 102.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 102.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 102.2
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 100.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 100.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 98.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 98.7
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 98.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 98.0
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 97.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 96.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 95.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 95.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 94.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 94.3
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 93.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 92.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 92.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 91.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 90.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 90.1
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 89.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 88.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 88.2
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 88.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 87.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 86.2
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 85.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 84.7
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 84.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 83.8
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 83.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 83.2
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 82.3
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 80.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 80.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 79.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 79.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 79.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 79.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 79.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 79.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 78.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 78.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 76.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 76.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 75.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 75.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 73.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 73.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 72.1
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 72.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 71.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 70.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 70.7
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 70.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 69.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 69.0
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 68.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 67.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 66.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 65.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 64.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 64.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 64.3
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 63.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 62.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 60.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 57.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 57.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 54.6
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 54.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 52.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 50.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 48.4
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 39.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 37.1
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 24.9
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 10.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

722.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 722.2
FF:10158-103A5 76 years, female 722.2

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

254.2
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 254.2
Samples: 1

Max nTPM: 254.2
Min nTPM: 254.2
Sample A 254.2
Midbrain
nTPM: 101.3
Samples: 1

Max nTPM: 101.3
Min nTPM: 101.3
Sample A 101.3
Superior colliculi
nTPM: 130.3
Samples: 1

Max nTPM: 130.3
Min nTPM: 130.3
Sample A 130.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

156.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 156.6
Samples: 3

Max nTPM: 192.6
Min nTPM: 135.7
Sample A Female 192.6
Sample B Female 135.7
Sample C Male 141.5
Midbrain
nTPM: 146.9
Samples: 3

Max nTPM: 226.8
Min nTPM: 106.3
Sample B Female 226.8
Sample C Male 107.5
Sample D Male 106.3
Periaqueductal gray
nTPM: 149.3
Samples: 3

Max nTPM: 189.8
Min nTPM: 111.9
Sample B Female 189.8
Sample C Male 111.9
Sample D Male 146.2
Superior colliculi
nTPM: 148.9
Samples: 4

Max nTPM: 167.9
Min nTPM: 112.6
Sample A Female 163.0
Sample B Female 112.6
Sample C Male 151.9
Sample D Male 167.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 72.9
Samples: 4

Max nTPM: 78.4
Min nTPM: 67.0
Sample A 67.8
Sample B 67.0
Sample C 78.4
Sample D 78.4

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.4
Rat sample Sample description nTPM
Midbrain
nTPM: 107.4
Samples: 4

Max nTPM: 113.4
Min nTPM: 103.2
Sample A 108.6
Sample A 113.4
Sample A 104.5
Sample A 103.2

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