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BETA
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  • BRAIN

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  • ENO1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Brain proteome
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:521.2 nTPM
HPA Brain:553.7 nTPM
GTEx:521.2 nTPM
FANTOM5:500.3 Scaled Tags Per Million
Macaque:34.4 nTPM
Mouse:610.7 nTPM
Rat:494.9 nTPM
Pig:498.3 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 130
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 200
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

553.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 358.5
2411 Female, age 72, unknown 448.1
1870 Female, age 42, unknown 388.5
2586 Male, age 75, left hemisphere 386.2
1827 Male, age 72, unknown 374.0
2828 Female, age 72, unknown 364.9
2019 Male, age 18, unknown 338.2
1833 Male, age 53, unknown 333.7
2666 Male, age 74, left hemisphere 325.0
2219 Male, age 76, both hemispheres 322.9
1830 Male, age 51, unknown 303.9
Dorsal raphe nucleus
nTPM: 553.7
2298 Female, age 72, unknown 739.4
2047 Male, age 72, unknown 614.0
1828 Male, age 53, unknown 522.9
2016 Female, age 72, unknown 470.4
2750 Male, age 76, both hemispheres 421.7
Inferior colliculus
nTPM: 468.8
2097 Female, age 72, unknown 622.9
1890 Male, age 53, unknown 531.3
1848 Female, age 42, unknown 394.8
2849 Male, age 72, unknown 326.4
Median raphe nucleus
nTPM: 506.1
2220 Male, age 76, midline 506.1
Periaquaductal grey, anterior
nTPM: 412.6
1947 Male, age 18, unknown 438.9
1795 Male, age 51, unknown 433.4
2502 Female, age 75, unknown 365.3
Periaquaductal grey, dorsal
nTPM: 395.8
2850 Male, age 76, both hemispheres 467.9
1840 Male, age 53, unknown 406.9
2464 Female, age 72, unknown 364.0
1831 Male, age 72, unknown 344.3
Periaquaductal grey, lateral
nTPM: 409.3
2272 Male, age 74, both hemispheres 472.0
2140 Male, age 76, both hemispheres 396.1
2053 Male, age 18, unknown 359.7
Pretectal area
nTPM: 397.1
2667 Female, age 75, unknown 510.5
2273 Male, age 74, both hemispheres 509.4
2224 Female, age 72, unknown 484.7
1817 Female, age 42, unknown 419.7
1944 Female, age 72, unknown 409.8
1816 Male, age 51, unknown 389.8
2825 Male, age 18, unknown 370.5
2007 Male, age 72, unknown 368.3
2316 Male, age 76, right hemisphere 320.1
1815 Male, age 53, unknown 311.5
2407 Male, age 75, both hemispheres 274.2
Red nucleus
nTPM: 364.8
1821 Female, age 72, unknown 480.0
2725 Female, age 75, unknown 429.2
1954 Female, age 42, unknown 422.2
2227 Male, age 72, unknown 392.7
2769 Male, age 72, unknown 390.4
2503 Female, age 72, unknown 375.5
1865 Male, age 51, unknown 359.2
1904 Male, age 53, unknown 356.4
2823 Male, age 76, right hemisphere 336.4
2785 Male, age 18, unknown 335.2
2584 Male, age 75, left hemisphere 252.2
2588 Male, age 74, left hemisphere 247.8
Substantia nigra
nTPM: 457.9
1916 Female, age 42, unknown 689.3
1941 Male, age 53, unknown 544.5
2699 Male, age 18, unknown 502.6
1851 Male, age 51, unknown 500.9
2241 Male, age 72, unknown 500.5
1889 Female, age 72, unknown 443.8
2409 Female, age 72, unknown 379.6
2665 Male, age 74, both hemispheres 366.1
2590 Female, age 75, unknown 327.3
2583 Male, age 75, right hemisphere 324.3
Superior colliculus
nTPM: 347.1
2087 Female, age 72, unknown 394.6
2261 Male, age 18, unknown 384.7
1796 Male, age 53, unknown 375.6
1995 Male, age 72, unknown 365.5
1913 Female, age 42, unknown 357.1
2587 Male, age 74, left hemisphere 339.1
2668 Female, age 75, unknown 337.7
1839 Male, age 51, unknown 328.4
2664 Male, age 75, both hemispheres 306.7
1895 Male, age 76, right hemisphere 281.9
Ventral tegmental area
nTPM: 465.5
1915 Female, age 42, unknown 533.9
1942 Male, age 51, unknown 482.0
2410 Female, age 72, unknown 469.7
2223 Female, age 72, unknown 459.6
2218 Male, age 76, both hemispheres 445.1
2021 Male, age 53, unknown 402.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

521.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 521.2
Samples: 183

Max nTPM: 1218.0
Min nTPM: 205.6
Std nTPM: 158.7
Median nTPM: 506.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1218.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 1084.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1020.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1015.1
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 928.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 906.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 882.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 789.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 778.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 774.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 760.0
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 756.2
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 748.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 738.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 728.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 720.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 717.1
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 714.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 705.5
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 704.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 692.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 687.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 685.9
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 683.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 680.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 673.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 662.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 660.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 658.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 652.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 644.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 642.8
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 640.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 639.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 637.7
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 634.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 633.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 630.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 629.3
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 627.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 622.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 620.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 615.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 615.2
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 611.8
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 611.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 601.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 599.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 594.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 593.9
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 593.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 593.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 593.0
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 589.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 582.7
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 582.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 582.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 580.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 575.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 571.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 568.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 567.8
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 562.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 559.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 558.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 556.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 556.2
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 550.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 549.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 549.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 545.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 542.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 541.6
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 540.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 539.7
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 536.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 529.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 528.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 526.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 525.1
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 525.1
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 525.0
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 524.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 521.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 520.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 519.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 517.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 513.7
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 509.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 507.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 506.7
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 506.2
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 506.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 505.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 500.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 499.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 498.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 492.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 490.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 488.1
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 485.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 484.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 483.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 481.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 481.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 479.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 478.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 477.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 477.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 476.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 473.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 469.4
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 468.0
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 464.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 462.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 461.9
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 461.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 456.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 449.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 446.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 443.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 442.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 439.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 435.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 435.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 435.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 433.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 430.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 427.0
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 425.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 424.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 421.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 420.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 419.2
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 418.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 412.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 412.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 412.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 408.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 403.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 402.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 397.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 393.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 390.3
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 388.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 388.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 383.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 377.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 373.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 371.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 370.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 369.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 366.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 366.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 366.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 362.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 360.9
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 360.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 359.6
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 358.5
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 349.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 346.3
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 346.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 344.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 340.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 335.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 334.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 333.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 329.9
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 327.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 326.7
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 323.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 312.9
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 307.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 305.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 302.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 297.1
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 290.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 286.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 277.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 265.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 236.6
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 205.6
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

500.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 500.3
FF:10158-103A5 76 years, female 500.3

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

34.4
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 15.7
Samples: 1

Max nTPM: 15.7
Min nTPM: 15.7
Sample A 15.7
Midbrain
nTPM: 32.1
Samples: 1

Max nTPM: 32.1
Min nTPM: 32.1
Sample A 32.1
Superior colliculi
nTPM: 34.4
Samples: 1

Max nTPM: 34.4
Min nTPM: 34.4
Sample A 34.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

498.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 471.4
Samples: 3

Max nTPM: 563.1
Min nTPM: 360.1
Sample A Female 563.1
Sample B Female 360.1
Sample C Male 491.1
Midbrain
nTPM: 423.0
Samples: 3

Max nTPM: 450.1
Min nTPM: 378.0
Sample B Female 450.1
Sample C Male 440.8
Sample D Male 378.0
Periaqueductal gray
nTPM: 377.7
Samples: 3

Max nTPM: 426.8
Min nTPM: 315.4
Sample B Female 391.0
Sample C Male 426.8
Sample D Male 315.4
Superior colliculi
nTPM: 498.3
Samples: 4

Max nTPM: 602.1
Min nTPM: 425.2
Sample A Female 602.1
Sample B Female 425.2
Sample C Male 501.6
Sample D Male 464.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

610.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 610.8
Samples: 4

Max nTPM: 628.9
Min nTPM: 593.9
Sample A 621.3
Sample B 628.9
Sample C 598.9
Sample D 593.9

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

494.9
Rat sample Sample description nTPM
Midbrain
nTPM: 494.9
Samples: 4

Max nTPM: 515.7
Min nTPM: 449.0
Sample A 515.7
Sample A 500.5
Sample A 514.4
Sample A 449.0

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