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BETA
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  • BRAIN

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  • SLC1A3
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:218.8 nTPM
HPA Brain:304.1 nTPM
GTEx:218.8 nTPM
FANTOM5:592.5 Scaled Tags Per Million
Macaque:326.1 nTPM
Mouse:101.2 nTPM
Rat:136.7 nTPM
Pig:670.5 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 50
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 5090
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

304.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 151.1
2828 Female, age 72, unknown 214.6
1827 Male, age 72, unknown 190.3
1870 Female, age 42, unknown 186.5
1833 Male, age 53, unknown 164.0
2219 Male, age 76, both hemispheres 153.3
2586 Male, age 75, left hemisphere 145.3
2411 Female, age 72, unknown 143.9
1830 Male, age 51, unknown 115.2
2019 Male, age 18, unknown 112.6
2666 Male, age 74, left hemisphere 85.2
Dorsal raphe nucleus
nTPM: 269.2
2298 Female, age 72, unknown 337.8
2016 Female, age 72, unknown 320.5
1828 Male, age 53, unknown 277.6
2047 Male, age 72, unknown 252.5
2750 Male, age 76, both hemispheres 157.8
Inferior colliculus
nTPM: 234.6
1848 Female, age 42, unknown 273.9
2849 Male, age 72, unknown 265.4
2097 Female, age 72, unknown 206.6
1890 Male, age 53, unknown 192.5
Median raphe nucleus
nTPM: 176.6
2220 Male, age 76, midline 176.6
Periaquaductal grey, anterior
nTPM: 228.1
1795 Male, age 51, unknown 263.1
2502 Female, age 75, unknown 212.1
1947 Male, age 18, unknown 209.1
Periaquaductal grey, dorsal
nTPM: 304.1
1840 Male, age 53, unknown 441.7
2850 Male, age 76, both hemispheres 345.6
2464 Female, age 72, unknown 240.5
1831 Male, age 72, unknown 188.6
Periaquaductal grey, lateral
nTPM: 277.3
2140 Male, age 76, both hemispheres 309.9
2053 Male, age 18, unknown 286.7
2272 Male, age 74, both hemispheres 235.4
Pretectal area
nTPM: 238.7
2273 Male, age 74, both hemispheres 378.6
1816 Male, age 51, unknown 312.7
1944 Female, age 72, unknown 287.8
2224 Female, age 72, unknown 275.5
2667 Female, age 75, unknown 264.6
1817 Female, age 42, unknown 228.4
2825 Male, age 18, unknown 210.1
2316 Male, age 76, right hemisphere 206.2
1815 Male, age 53, unknown 184.3
2407 Male, age 75, both hemispheres 144.4
2007 Male, age 72, unknown 133.0
Red nucleus
nTPM: 151.7
1954 Female, age 42, unknown 199.5
1821 Female, age 72, unknown 186.8
2503 Female, age 72, unknown 183.8
2725 Female, age 75, unknown 174.5
1904 Male, age 53, unknown 170.8
2823 Male, age 76, right hemisphere 168.5
2769 Male, age 72, unknown 166.5
2227 Male, age 72, unknown 165.9
1865 Male, age 51, unknown 135.5
2588 Male, age 74, left hemisphere 114.5
2785 Male, age 18, unknown 95.2
2584 Male, age 75, left hemisphere 59.2
Substantia nigra
nTPM: 235.7
2699 Male, age 18, unknown 386.5
1916 Female, age 42, unknown 336.0
2241 Male, age 72, unknown 264.0
2409 Female, age 72, unknown 256.0
1889 Female, age 72, unknown 237.5
1851 Male, age 51, unknown 218.7
2590 Female, age 75, unknown 210.0
2665 Male, age 74, both hemispheres 187.2
1941 Male, age 53, unknown 130.8
2583 Male, age 75, right hemisphere 130.6
Superior colliculus
nTPM: 207.8
2261 Male, age 18, unknown 262.3
2087 Female, age 72, unknown 256.9
1796 Male, age 53, unknown 244.5
1995 Male, age 72, unknown 237.6
1913 Female, age 42, unknown 200.2
2587 Male, age 74, left hemisphere 198.4
1839 Male, age 51, unknown 196.5
2668 Female, age 75, unknown 166.0
1895 Male, age 76, right hemisphere 159.7
2664 Male, age 75, both hemispheres 156.2
Ventral tegmental area
nTPM: 204.4
1915 Female, age 42, unknown 253.5
2410 Female, age 72, unknown 239.4
2021 Male, age 53, unknown 198.2
2218 Male, age 76, both hemispheres 192.9
1942 Male, age 51, unknown 182.2
2223 Female, age 72, unknown 160.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

218.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 218.8
Samples: 183

Max nTPM: 988.9
Min nTPM: 19.2
Std nTPM: 142.5
Median nTPM: 186.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 988.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 850.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 836.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 714.8
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 608.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 554.9
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 510.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 484.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 478.7
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 463.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 434.0
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 416.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 409.0
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 407.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 405.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 404.0
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 400.8
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 397.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 389.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 381.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 378.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 366.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 365.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 360.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 352.2
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 351.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 332.5
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 329.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 327.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 323.3
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 323.2
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 316.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 315.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 309.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 301.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 298.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 292.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 289.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 288.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 287.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 283.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 275.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 271.1
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 270.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 270.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 268.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 268.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 268.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 256.6
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 255.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 255.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 253.0
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 253.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 252.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 245.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 239.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 232.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 230.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 227.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 225.5
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 225.1
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 221.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 220.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 219.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 218.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 212.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 212.0
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 209.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 209.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 208.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 208.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 207.0
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 206.4
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 205.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 205.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 204.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 203.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 202.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 199.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 199.2
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 198.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 198.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 197.7
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 197.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 197.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 196.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 194.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 192.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 190.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 187.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 186.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 186.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 185.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 181.3
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 178.1
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 177.6
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 176.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 176.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 174.7
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 172.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 172.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 171.8
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 170.4
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 170.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 165.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 164.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 164.1
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 164.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 163.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 162.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 162.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 161.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 161.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 161.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 158.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 157.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 154.5
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 151.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 145.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 145.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 143.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 139.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 139.1
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 138.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 138.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 136.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 135.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 134.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 132.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 132.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 132.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 131.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 131.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 130.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 130.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 130.1
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 129.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 127.0
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 126.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 125.8
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 125.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 124.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 122.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 120.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 118.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 118.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 117.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 117.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 117.5
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 115.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 113.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 113.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 112.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 111.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 110.8
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 108.1
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 105.6
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 103.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 102.4
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 101.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 101.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 101.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 99.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 94.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 91.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 90.6
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 86.0
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 84.7
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 84.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 83.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 79.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 78.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 78.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 77.3
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 75.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 74.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 70.8
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 68.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 64.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 59.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 59.0
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 50.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

592.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 592.5
FF:10158-103A5 76 years, female 592.5

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

326.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 250.1
Samples: 1

Max nTPM: 250.1
Min nTPM: 250.1
Sample A 250.1
Midbrain
nTPM: 307.8
Samples: 1

Max nTPM: 307.8
Min nTPM: 307.8
Sample A 307.8
Superior colliculi
nTPM: 326.1
Samples: 1

Max nTPM: 326.1
Min nTPM: 326.1
Sample A 326.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

670.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 527.4
Samples: 3

Max nTPM: 608.9
Min nTPM: 409.1
Sample A Female 564.2
Sample B Female 409.1
Sample C Male 608.9
Midbrain
nTPM: 518.6
Samples: 3

Max nTPM: 689.9
Min nTPM: 389.0
Sample B Female 689.9
Sample C Male 476.8
Sample D Male 389.0
Periaqueductal gray
nTPM: 670.6
Samples: 3

Max nTPM: 764.9
Min nTPM: 538.6
Sample B Female 708.2
Sample C Male 764.9
Sample D Male 538.6
Superior colliculi
nTPM: 378.9
Samples: 4

Max nTPM: 456.9
Min nTPM: 214.1
Sample A Female 456.9
Sample B Female 214.1
Sample C Male 413.0
Sample D Male 431.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

101.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 101.1
Samples: 4

Max nTPM: 109.4
Min nTPM: 93.0
Sample A 109.4
Sample B 93.0
Sample C 97.5
Sample D 104.7

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

136.7
Rat sample Sample description nTPM
Midbrain
nTPM: 136.7
Samples: 4

Max nTPM: 146.3
Min nTPM: 127.4
Sample A 146.3
Sample A 136.8
Sample A 127.4
Sample A 136.4

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