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BETA
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  • BRAIN

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  • NFE2L1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:104.7 nTPM
HPA Brain:285.6 nTPM
GTEx:104.7 nTPM
FANTOM5:219.7 Scaled Tags Per Million
Macaque:114.5 nTPM
Mouse:189.0 nTPM
Rat:138.7 nTPM
Pig:107.9 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 80
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 50
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

285.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 227.7
1827 Male, age 72, unknown 271.3
2666 Male, age 74, left hemisphere 268.7
2828 Female, age 72, unknown 261.2
2586 Male, age 75, left hemisphere 251.8
1870 Female, age 42, unknown 212.9
1830 Male, age 51, unknown 211.1
1833 Male, age 53, unknown 210.9
2019 Male, age 18, unknown 209.9
2411 Female, age 72, unknown 205.4
2219 Male, age 76, both hemispheres 173.9
Dorsal raphe nucleus
nTPM: 231.2
2047 Male, age 72, unknown 260.4
1828 Male, age 53, unknown 246.5
2298 Female, age 72, unknown 225.0
2016 Female, age 72, unknown 217.8
2750 Male, age 76, both hemispheres 206.4
Inferior colliculus
nTPM: 200.2
1848 Female, age 42, unknown 212.7
1890 Male, age 53, unknown 201.1
2849 Male, age 72, unknown 200.5
2097 Female, age 72, unknown 186.4
Median raphe nucleus
nTPM: 238.7
2220 Male, age 76, midline 238.7
Periaquaductal grey, anterior
nTPM: 276.0
1947 Male, age 18, unknown 280.4
1795 Male, age 51, unknown 274.0
2502 Female, age 75, unknown 273.6
Periaquaductal grey, dorsal
nTPM: 222.1
1831 Male, age 72, unknown 255.0
2850 Male, age 76, both hemispheres 240.0
1840 Male, age 53, unknown 213.7
2464 Female, age 72, unknown 179.8
Periaquaductal grey, lateral
nTPM: 240.7
2272 Male, age 74, both hemispheres 262.9
2053 Male, age 18, unknown 238.3
2140 Male, age 76, both hemispheres 220.8
Pretectal area
nTPM: 263.8
2273 Male, age 74, both hemispheres 347.6
2407 Male, age 75, both hemispheres 308.1
2667 Female, age 75, unknown 304.0
1816 Male, age 51, unknown 287.8
1944 Female, age 72, unknown 270.2
2007 Male, age 72, unknown 249.9
1815 Male, age 53, unknown 246.2
1817 Female, age 42, unknown 241.3
2825 Male, age 18, unknown 240.4
2224 Female, age 72, unknown 204.0
2316 Male, age 76, right hemisphere 202.1
Red nucleus
nTPM: 197.1
2584 Male, age 75, left hemisphere 229.7
2725 Female, age 75, unknown 225.0
1821 Female, age 72, unknown 218.9
2785 Male, age 18, unknown 205.5
2588 Male, age 74, left hemisphere 205.3
1954 Female, age 42, unknown 190.8
1865 Male, age 51, unknown 190.5
2503 Female, age 72, unknown 188.7
2769 Male, age 72, unknown 184.1
2227 Male, age 72, unknown 183.1
1904 Male, age 53, unknown 176.5
2823 Male, age 76, right hemisphere 167.2
Substantia nigra
nTPM: 285.6
1916 Female, age 42, unknown 370.5
1941 Male, age 53, unknown 330.7
2665 Male, age 74, both hemispheres 318.7
1851 Male, age 51, unknown 300.1
2699 Male, age 18, unknown 291.0
1889 Female, age 72, unknown 254.6
2583 Male, age 75, right hemisphere 253.6
2590 Female, age 75, unknown 250.6
2409 Female, age 72, unknown 245.3
2241 Male, age 72, unknown 240.9
Superior colliculus
nTPM: 233.7
2664 Male, age 75, both hemispheres 319.1
2587 Male, age 74, left hemisphere 278.3
1796 Male, age 53, unknown 256.3
2261 Male, age 18, unknown 246.1
2087 Female, age 72, unknown 239.8
1839 Male, age 51, unknown 229.4
1995 Male, age 72, unknown 203.5
1913 Female, age 42, unknown 199.3
2668 Female, age 75, unknown 195.4
1895 Male, age 76, right hemisphere 169.4
Ventral tegmental area
nTPM: 246.8
1915 Female, age 42, unknown 279.7
2410 Female, age 72, unknown 276.8
2218 Male, age 76, both hemispheres 239.9
1942 Male, age 51, unknown 232.8
2021 Male, age 53, unknown 227.1
2223 Female, age 72, unknown 224.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 104.7
Samples: 183

Max nTPM: 239.7
Min nTPM: 59.2
Std nTPM: 24.9
Median nTPM: 99.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 239.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 184.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 177.3
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 175.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 172.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 163.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 154.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 154.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 153.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 151.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 149.2
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 146.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 145.6
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 145.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 144.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 140.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 140.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 140.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 138.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 136.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 136.0
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 133.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 133.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 132.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 129.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 128.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 128.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 127.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 126.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.1
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 125.7
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 125.2
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 124.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 124.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 122.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 122.2
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 121.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 121.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 121.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 120.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 119.3
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 119.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 115.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 115.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 115.2
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 114.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 114.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 113.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 113.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 113.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 112.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 112.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 111.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 111.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 110.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 110.1
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 109.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 109.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 108.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 107.9
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 107.5
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 107.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 107.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 106.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 106.5
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 106.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 106.3
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 105.8
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 105.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 105.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 105.4
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 105.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 105.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 104.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 104.3
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 104.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 104.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 103.7
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 103.0
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 102.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 102.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 102.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 102.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 102.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 101.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 101.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 101.1
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 100.0
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 99.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 99.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 99.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 99.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 98.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 97.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 97.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 97.3
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 97.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 97.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 97.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 96.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 96.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 96.5
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 96.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 96.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 96.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 95.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 95.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 94.9
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 94.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 94.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 94.3
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 94.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 94.1
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 93.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 93.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 92.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 92.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 92.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 92.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 91.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 91.6
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 91.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 91.5
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 90.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 90.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 90.8
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 90.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 90.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 90.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 89.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 89.3
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 89.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 89.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 89.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 88.4
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 87.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 87.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 87.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 86.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 86.6
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 86.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 86.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 86.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 86.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 85.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 85.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85.3
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 85.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 85.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 84.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 84.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 84.0
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 84.0
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 83.9
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 83.6
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 82.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 82.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 82.6
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 81.8
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 81.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 81.4
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 81.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 80.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80.1
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 79.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 79.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 79.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 79.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 78.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 77.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 77.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 77.0
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 76.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 75.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 74.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 74.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 73.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 71.2
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 69.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 69.4
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 65.8
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 59.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

219.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 219.7
FF:10158-103A5 76 years, female 219.7

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

114.5
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 86.6
Samples: 1

Max nTPM: 86.6
Min nTPM: 86.6
Sample A 86.6
Midbrain
nTPM: 100.8
Samples: 1

Max nTPM: 100.8
Min nTPM: 100.8
Sample A 100.8
Superior colliculi
nTPM: 114.5
Samples: 1

Max nTPM: 114.5
Min nTPM: 114.5
Sample A 114.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 100.3
Samples: 3

Max nTPM: 108.0
Min nTPM: 85.9
Sample A Female 108.0
Sample B Female 85.9
Sample C Male 107.1
Midbrain
nTPM: 91.8
Samples: 3

Max nTPM: 110.9
Min nTPM: 73.9
Sample B Female 73.9
Sample C Male 110.9
Sample D Male 90.6
Periaqueductal gray
nTPM: 85.1
Samples: 3

Max nTPM: 95.8
Min nTPM: 78.8
Sample B Female 78.8
Sample C Male 95.8
Sample D Male 80.7
Superior colliculi
nTPM: 107.9
Samples: 4

Max nTPM: 112.4
Min nTPM: 103.2
Sample A Female 110.7
Sample B Female 112.4
Sample C Male 103.2
Sample D Male 105.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

189.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 189.0
Samples: 4

Max nTPM: 209.6
Min nTPM: 175.8
Sample A 175.8
Sample B 209.6
Sample C 190.3
Sample D 180.4

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

138.7
Rat sample Sample description nTPM
Midbrain
nTPM: 138.7
Samples: 4

Max nTPM: 142.5
Min nTPM: 132.8
Sample A 142.5
Sample A 142.1
Sample A 132.8
Sample A 137.3

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