Brain tissue expression of GSTP1 in pons

PONS - Expression summary

Protein expressionⁱ

No data

RNA expressionⁱ

HPA Brain:	299.1	nTPM
FANTOM5:	120.0	Scaled Tags Per Million

Macaque:	283.8	nTPM
Mouse:	233.7	nTPM
Rat:	174.5	nTPM

PONS - SINGLE NUCLEI RNA EXPRESSIONⁱ RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right). - UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon - The BAR CHART* shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

SINGLE NUCLEI BRAIN - PONS, NEURONSⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Excitatory (VGLUT1/2)
	c-2	Excitatory (VGLUT1) ETV1+ Z...
	c-3	Excitatory (VGLUT1/2)
	c-4	Excitatory (VGLUT1) ETV1+ Z...
	c-5	Excitatory (VGLUT1/2)
	c-6	Excitatory (VGLUT1/2)
	c-7	Excitatory (VGLUT1/2)
	c-8	Inhibitory (GAD1/2) SLC6A5+
	c-9	Excitatory (VGLUT2)
	c-10	Excitatory (VGLUT1/2)
	c-11	Excitatory (VGLUT1/2)
	c-12	Unassigned
	c-13	Inhibitory (GAD1/2) RORB+ K
	c-14	Inhibitory (GAD1/2) SST+
	c-15	Excitatory (VGLUT1) ETV1+ Z...
	c-16	Excitatory (VGLUT2)
	c-17	Excitatory (VGLUT1/2)
	c-18	Inhibitory (GAD1/2)
	c-19	Inhibitory (GAD1) PENK+ SST
	c-20	Excitatory (VGLUT2) FOXP2+
	c-21	Excitatory (VGLUT2) LMX1A+
	c-22	Excitatory (VGLUT2) MEIS2+
	c-23	Inhibitory (GAD1/2) SLC6A5+...
	c-24	Inhibitory (GAD1/2) SLC6A5+...
	c-25	Serotonergic SLC6A4+ SLC18A...
	c-26	Inhibitory (GAD1/2) PVALB+ ...
	c-27	Excitatory (VGLUT2)
	c-28	(VGLUT3) PENK+
	c-29	MEIS2+
	c-30	LMX1A+
	c-31	Inhibitory (GAD1/2) TAC1+
	c-32	Excitatory (VGLUT2) PVALB+
	c-33	Inhibitory (GAD1/2) PVALB+ ...
	c-34	Inhibitory (GAD1/2)
	c-35	Excitatory (VGLUT2) SST+ ME...
	c-36	LC Noradrenergic SLC6A2+ SL...
	c-37	Excitatory (VGLUT2) CRH+ FO...
	c-38	Inhibitory (GAD1/2) PVALB+ ...
	c-39	Excitatory (VGLUT2)
	c-40	Excitatory (VGLUT2) PVALB+
Show allShow less

This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - PONS, NON-NEURONALⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Oligodendrocytes
	c-2	Oligodendrocytes
	c-3	Oligodendrocyte progenitor ...
	c-4	Oligodendrocytes
	c-5	Oligodendrocytes
	c-6	Oligodendrocytes
	c-7	Microglia
	c-8	Astrocytes
	c-9	Oligodendrocytes
	c-10	Astrocytes (CD44+)
	c-11	Oligodendrocytes
	c-12	Fibroblasts
	c-13	Vascular endothelial cells
	c-14	Pericytes
	c-15	Ependymal cells
	c-16	Lymphocytes
	c-17	Macrophages
	c-18	Microglia (SPP1+ HIF1A+)
	c-19	Bergmann glia
	c-20	Immature oligodendrocytes
	c-21	Oligodendrocyte progenitor ...
	c-22	Vascular smooth muscle cell
	c-23	Monocytes
	c-24	Immature oligodendrocytes
	c-25	Fibroblasts (BNC2+ KCNMA1+ ...
	c-26	Choroid plexus epithelial c...
	c-27	Macrophage Microglia double
	c-28	OPC & lymphocytes doublets
Show allShow less

This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	299.1

Sample id

Sample description

nTPM

Anterior cochlear nucleus, ventral
nTPM: 213.1

2188	Female, age 91, both hemispheres	232.0
2090	Male, age 80, both hemispheres	222.0
2301	Female, age 85, both hemispheres	214.1
1984	Male, age 76, both hemispheres	184.4

Dorsal cochlear nucleus
nTPM: 228.5

2370	Male, age 61, both hemispheres	258.9
2187	Female, age 91, both hemispheres	232.3
2058	Male, age 76, both hemispheres	224.8
2802	Male, age 74, right hemisphere	217.2
2378	Male, age 80, both hemispheres	209.1

Dorsal tegmental nucleus
nTPM: 264.0

2358	Male, age 61, both hemispheres	326.9
2083	Male, age 80, both hemispheres	268.2
1936	Male, age 76, left hemisphere	232.7
2326	Male, age 74, both hemispheres	228.1

Dorsolateral tegmental area
nTPM: 248.2

2360	Male, age 74, both hemispheres	270.8
2337	Male, age 61, both hemispheres	266.9
2654	Male, age 80, both hemispheres	262.1
2751	Female, age 85, both hemispheres	223.9
2141	Male, age 76, both hemispheres	217.5

Kolliker-Fuse nucleus
nTPM: 252.7

2315	Male, age 76, right hemisphere	291.7
2163	Male, age 80, both hemispheres	237.8
2793	Female, age 91, left hemisphere	228.6

Lateral lemniscal nuclei
nTPM: 203.9

2746	Female, age 85, left hemisphere	246.7
2169	Male, age 76, both hemispheres	217.8
2036	Male, age 80, both hemispheres	199.6
2320	Female, age 91, left hemisphere	188.6
2453	Male, age 74, right hemisphere	167.0

Lateral parabrachial nucleus
nTPM: 251.4

2792	Male, age 76, both hemispheres	265.1
2790	Male, age 61, both hemispheres	257.4
2139	Female, age 85, right hemisphere	241.9
2013	Male, age 80, both hemispheres	241.1

Lateral vestibular nucleus
nTPM: 236.6

2311	Male, age 80, both hemispheres	255.2
2184	Male, age 76, both hemispheres	218.1

Locus coeruleus
nTPM: 299.1

1980	Male, age 76, both hemispheres	318.8
2014	Male, age 55, unknown	317.3
2123	Female, age 91, both hemispheres	312.0
2317	Female, age 72, unknown	312.0
2788	Male, age 74, unknown	311.2
2720	Male, age 74, both hemispheres	271.6
2162	Male, age 80, both hemispheres	250.8

Medial parabrachial nucleus
nTPM: 240.0

2170	Female, age 91, both hemispheres	277.5
2156	Male, age 61, both hemispheres	249.3
2854	Male, age 80, both hemispheres	228.5
2786	Male, age 76, both hemispheres	224.1
2463	Female, age 85, right hemisphere	220.8

Medial periolivary nuclei
nTPM: 209.6

2063	Male, age 76, both hemispheres	228.9
2171	Female, age 85, both hemispheres	219.8
2791	Male, age 74, right hemisphere	215.8
2081	Male, age 80, both hemispheres	211.2
2458	Female, age 91, both hemispheres	172.3

Motor facial nucleus
nTPM: 203.0

2062	Male, age 76, both hemispheres	233.9
2365	Male, age 74, right hemisphere	216.2
2126	Male, age 61, both hemispheres	209.7
2697	Female, age 85, both hemispheres	204.8
2795	Female, age 91, both hemispheres	190.1
2327	Male, age 80, both hemispheres	163.4

Motor trigeminal nucleus
nTPM: 205.9

2335	Male, age 61, both hemispheres	230.5
2309	Male, age 76, both hemispheres	224.1
2560	Male, age 74, both hemispheres	204.2
2321	Female, age 91, both hemispheres	187.6
2079	Male, age 80, both hemispheres	183.0

Nuclei of the trapezoid body
nTPM: 204.0

1983	Male, age 76, both hemispheres	227.8
2159	Male, age 61, both hemispheres	212.2
2735	Female, age 85, both hemispheres	210.3
2166	Male, age 80, both hemispheres	193.8
2368	Female, age 91, both hemispheres	175.7

Nucleus raphe magnus
nTPM: 210.6

2051	Male, age 76, both hemispheres	262.8
2160	Male, age 61, both hemispheres	215.6
2172	Female, age 85, both hemispheres	210.8
2455	Male, age 74, both hemispheres	200.5
2328	Male, age 80, both hemispheres	188.6
2459	Female, age 91, both hemispheres	185.1

Paramedian reticular nucleus
nTPM: 248.0

2057	Male, age 80, both hemispheres	277.0
2313	Male, age 61, both hemispheres	247.5
2050	Female, age 85, both hemispheres	238.9
2052	Male, age 76, both hemispheres	228.8

Pedunculopontine tegmental nucleus
nTPM: 248.1

2334	Male, age 80, both hemispheres	275.0
2338	Male, age 61, both hemispheres	240.4
1921	Female, age 85, both hemispheres	229.1

Pontine nuclei
nTPM: 220.5

2787	Female, age 85, both hemispheres	266.8
1968	Male, age 76, left hemisphere	234.3
2109	Female, age 72, unknown	227.8
2319	Female, age 91, both hemispheres	216.1
2115	Male, age 80, left hemisphere	211.8
2454	Male, age 74, left hemisphere	203.3
2727	Male, age 61, right hemisphere	203.1
1863	Male, age 55, unknown	200.4

Pontine raphe nucleus
nTPM: 252.1

2853	Male, age 76, midline	270.5
2122	Female, age 85, midline	233.6

Posteroventral cochlear nucleus
nTPM: 233.4

2371	Male, age 61, both hemispheres	262.4
2070	Male, age 76, both hemispheres	234.6
2752	Female, age 85, both hemispheres	230.2
2135	Female, age 91, both hemispheres	225.2
2341	Male, age 80, both hemispheres	214.4

Principal sensory trigeminal nucleus
nTPM: 203.5

2324	Male, age 76, both hemispheres	226.3
2158	Male, age 61, both hemispheres	215.3
2008	Male, age 80, left hemisphere	189.5
2367	Female, age 91, left hemisphere	182.8

Reticular pontine nucleus, caudal
nTPM: 198.8

2092	Male, age 76, both hemispheres	234.9
2559	Male, age 74, both hemispheres	196.9
2457	Female, age 91, both hemispheres	193.8
2332	Male, age 80, right hemisphere	169.6

Reticular pontine nucleus, oral
nTPM: 236.2

1939	Male, age 80, both hemispheres	263.4
2167	Male, age 76, both hemispheres	239.2
2012	Female, age 85, both hemispheres	238.1
2361	Male, age 74, both hemispheres	234.4
2366	Female, age 91, both hemispheres	206.0

Reticulotegmental nucleus
nTPM: 214.9

2325	Male, age 76, both hemispheres	216.6
2333	Male, age 80, both hemispheres	216.3
2452	Male, age 74, both hemispheres	213.4
2322	Female, age 91, both hemispheres	213.2

Spinal trigeminal nucleus, oral
nTPM: 216.4

1978	Male, age 76, both hemispheres	225.2
2164	Male, age 80, both hemispheres	218.1
2737	Female, age 85, both hemispheres	205.7

Subcoeruleus area
nTPM: 223.9

2323	Female, age 91, left hemisphere	236.4
1958	Male, age 80, both hemispheres	232.2
2369	Female, age 85, left hemisphere	228.9
2451	Male, age 74, both hemispheres	225.9
2089	Male, age 76, left hemisphere	196.2

Superior olive
nTPM: 210.3

2364	Male, age 74, right hemisphere	231.0
2020	Male, age 76, both hemispheres	225.4
1875	Female, age 85, both hemispheres	221.3
2329	Male, age 80, right hemisphere	188.1
2561	Female, age 91, both hemispheres	185.9

Ventral periolivary nuclei
nTPM: 205.7

2023	Male, age 76, both hemispheres	230.7
2130	Female, age 85, both hemispheres	224.5
2165	Male, age 80, both hemispheres	204.2
2794	Female, age 91, left hemisphere	163.2

Ventrolateral tegmental area, A5 NE cell group
nTPM: 218.8

2359	Male, age 61, both hemispheres	245.5
2840	Female, age 85, both hemispheres	244.8
2161	Male, age 80, both hemispheres	215.7
1959	Male, age 76, both hemispheres	213.8
2456	Female, age 91, both hemispheres	196.8
2449	Male, age 74, both hemispheres	196.3

PONS - FANTOM5 CAGEⁱ

Max subtype Scaled Tags Per Millionⁱ Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.	120.0

FANTOM5 sample id

Sample description

Scaled Tags Per Million

Locus coeruleus
Scaled Tags Per Million: 120.0

FF:10165-103B3	76 years, female	138.5
FF:10182-103D2	60 years, female	101.6

Pons
Scaled Tags Per Million: 72.2

FF:10033-101E6

18-54 years, mixed

72.2

PONS - Macaque RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	283.8

Macaque sample

Sample description

nTPM

Pons
nTPM: 283.9

Samples: 2

Max nTPM: 359.6
Min nTPM: 208.1

Sample A		208.1
Sample B		359.6

PONS - Mouse RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	233.7

Mouse sample

Sample description

nTPM

Pons
nTPM: 2.3

Samples: 4

Max nTPM: 3.2
Min nTPM: 1.7

Sample A		2.2
Sample B		1.7
Sample C		3.2
Sample D		2.0

PONS - Rat RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	174.5

Rat sample

Sample description

nTPM

Pons
nTPM: 174.5

Samples: 4

Max nTPM: 185.5
Min nTPM: 154.7

Sample A		179.5
Sample A		185.5
Sample A		178.2
Sample A		154.7