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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:69.4 nTPM
HPA Brain:352.4 nTPM
GTEx:69.4 nTPM
FANTOM5:203.0 Scaled Tags Per Million
Macaque:87.8 nTPM
Mouse:69.6 nTPM
Rat:45.2 nTPM
Pig:57.5 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 780
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 2510
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

352.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 179.4
2828 Female, age 72, unknown 266.3
2586 Male, age 75, left hemisphere 247.2
2666 Male, age 74, left hemisphere 207.1
1827 Male, age 72, unknown 192.1
1870 Female, age 42, unknown 174.2
1833 Male, age 53, unknown 155.6
1830 Male, age 51, unknown 153.5
2219 Male, age 76, both hemispheres 145.0
2019 Male, age 18, unknown 135.0
2411 Female, age 72, unknown 117.7
Dorsal raphe nucleus
nTPM: 229.0
2016 Female, age 72, unknown 343.9
1828 Male, age 53, unknown 246.4
2047 Male, age 72, unknown 225.5
2298 Female, age 72, unknown 195.2
2750 Male, age 76, both hemispheres 134.3
Inferior colliculus
nTPM: 184.5
2849 Male, age 72, unknown 208.2
1890 Male, age 53, unknown 198.2
1848 Female, age 42, unknown 193.9
2097 Female, age 72, unknown 137.7
Median raphe nucleus
nTPM: 166.7
2220 Male, age 76, midline 166.7
Periaquaductal grey, anterior
nTPM: 226.7
1795 Male, age 51, unknown 294.6
1947 Male, age 18, unknown 201.5
2502 Female, age 75, unknown 184.0
Periaquaductal grey, dorsal
nTPM: 280.9
2850 Male, age 76, both hemispheres 356.1
1831 Male, age 72, unknown 333.2
1840 Male, age 53, unknown 250.0
2464 Female, age 72, unknown 184.1
Periaquaductal grey, lateral
nTPM: 352.4
2053 Male, age 18, unknown 357.3
2140 Male, age 76, both hemispheres 356.1
2272 Male, age 74, both hemispheres 343.8
Pretectal area
nTPM: 241.6
2273 Male, age 74, both hemispheres 446.6
2407 Male, age 75, both hemispheres 339.0
2825 Male, age 18, unknown 250.3
2224 Female, age 72, unknown 243.5
2316 Male, age 76, right hemisphere 234.5
2667 Female, age 75, unknown 228.1
1944 Female, age 72, unknown 214.3
1815 Male, age 53, unknown 204.7
1816 Male, age 51, unknown 202.6
1817 Female, age 42, unknown 168.6
2007 Male, age 72, unknown 125.1
Red nucleus
nTPM: 150.6
2725 Female, age 75, unknown 215.1
2823 Male, age 76, right hemisphere 173.4
1865 Male, age 51, unknown 157.4
2584 Male, age 75, left hemisphere 151.7
1954 Female, age 42, unknown 146.4
2227 Male, age 72, unknown 145.6
2503 Female, age 72, unknown 139.9
1904 Male, age 53, unknown 138.9
2769 Male, age 72, unknown 137.7
1821 Female, age 72, unknown 137.4
2588 Male, age 74, left hemisphere 132.2
2785 Male, age 18, unknown 131.3
Substantia nigra
nTPM: 199.1
2699 Male, age 18, unknown 304.8
2590 Female, age 75, unknown 227.8
2583 Male, age 75, right hemisphere 220.1
1851 Male, age 51, unknown 194.9
1941 Male, age 53, unknown 183.4
2665 Male, age 74, both hemispheres 182.8
1916 Female, age 42, unknown 181.8
2409 Female, age 72, unknown 173.5
2241 Male, age 72, unknown 165.9
1889 Female, age 72, unknown 155.8
Superior colliculus
nTPM: 244.1
1995 Male, age 72, unknown 354.2
2664 Male, age 75, both hemispheres 317.8
1913 Female, age 42, unknown 309.4
2587 Male, age 74, left hemisphere 251.3
2087 Female, age 72, unknown 237.2
1796 Male, age 53, unknown 228.2
2261 Male, age 18, unknown 220.3
1839 Male, age 51, unknown 201.6
2668 Female, age 75, unknown 170.5
1895 Male, age 76, right hemisphere 150.2
Ventral tegmental area
nTPM: 211.7
2021 Male, age 53, unknown 273.8
1915 Female, age 42, unknown 224.6
1942 Male, age 51, unknown 223.8
2223 Female, age 72, unknown 209.4
2218 Male, age 76, both hemispheres 192.7
2410 Female, age 72, unknown 146.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

69.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 69.4
Samples: 183

Max nTPM: 157.9
Min nTPM: 18.8
Std nTPM: 29.7
Median nTPM: 68.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 157.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 142.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 141.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 141.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 139.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 135.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 130.4
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 129.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 128.1
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 127.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 127.4
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 124.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 124.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 122.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 120.5
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 117.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 116.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 112.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 111.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 110.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 109.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 109.0
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 107.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 106.6
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 105.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 103.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 102.7
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 102.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 101.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 100.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 100.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 99.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 99.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 98.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 98.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 98.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 94.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 94.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 93.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 93.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 93.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 91.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 91.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 89.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 88.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 87.8
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 87.2
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 87.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 87.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 85.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 85.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 84.0
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 81.1
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 80.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 79.5
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 79.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 78.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 78.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 77.2
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 77.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 77.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 76.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 76.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 76.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 75.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 75.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 74.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 74.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 74.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 73.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 73.5
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 73.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 72.6
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 72.4
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 72.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 71.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 71.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 71.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 70.6
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 70.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 70.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 69.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 68.9
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 68.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 68.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 68.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 68.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 68.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 68.1
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 68.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 68.1
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 68.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 68.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 67.9
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 67.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 65.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 65.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 65.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 64.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 63.3
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 63.2
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 62.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 61.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 60.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 59.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 58.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 58.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 58.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 58.0
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 57.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 56.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 56.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 56.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 56.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 53.3
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 52.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 52.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 52.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.5
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 52.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 51.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 51.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 51.2
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 51.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 50.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 50.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 50.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 48.9
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 48.7
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 47.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 46.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 46.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.8
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 46.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 46.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 45.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 44.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 44.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 44.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 44.1
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 44.0
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 43.5
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 43.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 43.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 42.6
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 42.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 42.1
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 42.1
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 41.9
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 41.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 41.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 40.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 40.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 40.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 39.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 38.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 38.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 38.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 38.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 36.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 36.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 35.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 34.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 34.2
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 34.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 34.1
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 33.7
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 33.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 33.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 32.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 32.2
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 31.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 30.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 30.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 27.6
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 27.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 26.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 26.0
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 25.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 25.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 24.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 24.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 18.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

203.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 203.0
FF:10158-103A5 76 years, female 203.0

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

87.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 62.5
Samples: 1

Max nTPM: 62.5
Min nTPM: 62.5
Sample A 62.5
Midbrain
nTPM: 87.8
Samples: 1

Max nTPM: 87.8
Min nTPM: 87.8
Sample A 87.8
Superior colliculi
nTPM: 74.7
Samples: 1

Max nTPM: 74.7
Min nTPM: 74.7
Sample A 74.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 55.9
Samples: 3

Max nTPM: 71.9
Min nTPM: 46.8
Sample A Female 46.8
Sample B Female 71.9
Sample C Male 49.1
Midbrain
nTPM: 42.1
Samples: 3

Max nTPM: 62.2
Min nTPM: 28.9
Sample B Female 28.9
Sample C Male 62.2
Sample D Male 35.2
Periaqueductal gray
nTPM: 50.7
Samples: 3

Max nTPM: 58.1
Min nTPM: 41.1
Sample B Female 41.1
Sample C Male 58.1
Sample D Male 52.8
Superior colliculi
nTPM: 57.5
Samples: 4

Max nTPM: 81.6
Min nTPM: 45.3
Sample A Female 45.3
Sample B Female 81.6
Sample C Male 52.0
Sample D Male 51.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

69.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 69.6
Samples: 4

Max nTPM: 75.7
Min nTPM: 63.3
Sample A 64.0
Sample B 63.3
Sample C 75.3
Sample D 75.7

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.2
Rat sample Sample description nTPM
Midbrain
nTPM: 45.2
Samples: 4

Max nTPM: 47.6
Min nTPM: 41.6
Sample A 47.6
Sample A 44.9
Sample A 41.6
Sample A 46.8

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