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BETA
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  • RPS16
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:908.1 nTPM
HPA Brain:311.9 nTPM
GTEx:908.1 nTPM
FANTOM5:339.9 Scaled Tags Per Million
Macaque:1.8 nTPM
Mouse:23.5 nTPM
Rat:0.6 nTPM
Pig:0.0 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 100
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 260
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

311.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 284.9
2586 Male, age 75, left hemisphere 339.3
2666 Male, age 74, left hemisphere 338.5
1870 Female, age 42, unknown 316.6
2828 Female, age 72, unknown 289.3
2411 Female, age 72, unknown 282.2
1833 Male, age 53, unknown 270.8
1830 Male, age 51, unknown 267.4
2219 Male, age 76, both hemispheres 257.5
1827 Male, age 72, unknown 243.6
2019 Male, age 18, unknown 243.6
Dorsal raphe nucleus
nTPM: 273.2
2016 Female, age 72, unknown 293.0
2298 Female, age 72, unknown 274.5
1828 Male, age 53, unknown 271.0
2750 Male, age 76, both hemispheres 270.6
2047 Male, age 72, unknown 256.8
Inferior colliculus
nTPM: 265.1
1890 Male, age 53, unknown 291.3
2849 Male, age 72, unknown 271.8
1848 Female, age 42, unknown 253.7
2097 Female, age 72, unknown 243.6
Median raphe nucleus
nTPM: 234.8
2220 Male, age 76, midline 234.8
Periaquaductal grey, anterior
nTPM: 270.7
2502 Female, age 75, unknown 321.6
1795 Male, age 51, unknown 245.7
1947 Male, age 18, unknown 244.7
Periaquaductal grey, dorsal
nTPM: 249.3
1831 Male, age 72, unknown 272.8
1840 Male, age 53, unknown 257.0
2850 Male, age 76, both hemispheres 235.6
2464 Female, age 72, unknown 231.7
Periaquaductal grey, lateral
nTPM: 239.5
2053 Male, age 18, unknown 287.7
2140 Male, age 76, both hemispheres 225.7
2272 Male, age 74, both hemispheres 205.0
Pretectal area
nTPM: 252.7
2316 Male, age 76, right hemisphere 289.8
1815 Male, age 53, unknown 276.4
1817 Female, age 42, unknown 272.2
2825 Male, age 18, unknown 260.1
2007 Male, age 72, unknown 259.3
2407 Male, age 75, both hemispheres 256.3
2224 Female, age 72, unknown 253.6
1816 Male, age 51, unknown 240.8
1944 Female, age 72, unknown 233.8
2667 Female, age 75, unknown 230.2
2273 Male, age 74, both hemispheres 206.8
Red nucleus
nTPM: 311.9
2503 Female, age 72, unknown 383.8
1865 Male, age 51, unknown 347.9
1904 Male, age 53, unknown 328.7
1821 Female, age 72, unknown 324.7
2584 Male, age 75, left hemisphere 324.7
2769 Male, age 72, unknown 319.8
2725 Female, age 75, unknown 308.9
2227 Male, age 72, unknown 303.8
2785 Male, age 18, unknown 293.9
2588 Male, age 74, left hemisphere 284.0
2823 Male, age 76, right hemisphere 262.1
1954 Female, age 42, unknown 260.4
Substantia nigra
nTPM: 309.2
2699 Male, age 18, unknown 409.3
1851 Male, age 51, unknown 364.1
2665 Male, age 74, both hemispheres 351.6
2409 Female, age 72, unknown 327.9
1916 Female, age 42, unknown 303.5
2590 Female, age 75, unknown 282.8
1889 Female, age 72, unknown 279.7
2241 Male, age 72, unknown 269.8
2583 Male, age 75, right hemisphere 253.5
1941 Male, age 53, unknown 249.7
Superior colliculus
nTPM: 282.8
2587 Male, age 74, left hemisphere 343.2
1913 Female, age 42, unknown 337.2
1995 Male, age 72, unknown 333.2
1796 Male, age 53, unknown 279.7
2664 Male, age 75, both hemispheres 279.6
2668 Female, age 75, unknown 276.7
1839 Male, age 51, unknown 271.5
1895 Male, age 76, right hemisphere 261.6
2261 Male, age 18, unknown 223.6
2087 Female, age 72, unknown 221.7
Ventral tegmental area
nTPM: 288.0
1915 Female, age 42, unknown 336.1
2223 Female, age 72, unknown 299.3
2410 Female, age 72, unknown 295.1
2021 Male, age 53, unknown 278.5
1942 Male, age 51, unknown 266.7
2218 Male, age 76, both hemispheres 252.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

908.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 908.1
Samples: 183

Max nTPM: 2276.4
Min nTPM: 295.5
Std nTPM: 325.1
Median nTPM: 847.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2276.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2040.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1976.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 1780.9
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 1752.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1658.0
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 1650.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1511.3
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 1501.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1449.7
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 1438.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1436.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1405.1
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 1386.9
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 1353.8
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 1326.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1311.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1302.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1300.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1295.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 1282.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1272.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1272.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1261.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1246.9
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 1244.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1227.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1221.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 1214.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1204.9
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 1199.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1195.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1181.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1174.5
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 1165.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1141.7
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 1135.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1127.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1121.3
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 1116.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1115.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1110.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1105.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 1083.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 1076.6
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 1071.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1067.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1061.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 1056.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1054.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1052.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1039.6
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 1039.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1038.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1031.7
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 1027.8
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 1027.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1024.8
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 1024.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1020.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1019.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1011.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1008.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 996.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 992.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 989.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 983.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 977.8
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 975.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 973.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 965.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 963.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 963.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 962.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 957.0
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 930.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 928.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 926.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 918.7
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 918.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 917.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 917.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 910.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 899.7
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 895.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 895.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 887.5
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 883.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 876.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 861.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 849.8
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 847.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 844.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 833.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 826.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 823.8
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 823.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 819.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 819.7
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 819.5
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 808.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 801.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 798.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 794.7
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 793.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 793.0
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 790.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 789.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 785.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 779.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 766.3
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 762.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 758.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 758.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 756.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 755.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 746.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 743.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 741.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 740.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 737.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 733.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 726.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 722.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 715.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 715.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 711.2
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 710.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 705.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 696.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 694.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 689.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 689.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 683.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 680.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 680.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 678.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 678.2
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 674.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 672.9
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 671.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 664.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 663.8
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 656.4
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 656.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 650.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 649.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 646.9
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 633.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 632.4
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 626.3
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 623.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 606.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 605.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 605.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 603.0
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 601.8
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 600.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 586.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 581.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 574.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 571.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 569.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 569.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 564.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 563.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 563.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 557.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 543.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 541.7
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 541.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 525.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 510.9
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 503.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 490.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 478.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 444.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 422.3
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 379.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 373.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 356.4
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 312.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 295.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

339.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 339.9
FF:10158-103A5 76 years, female 339.9

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 1.8
Samples: 1

Max nTPM: 1.8
Min nTPM: 1.8
Sample A 1.8
Midbrain
nTPM: 0.5
Samples: 1

Max nTPM: 0.5
Min nTPM: 0.5
Sample A 0.5
Superior colliculi
nTPM: 0.9
Samples: 1

Max nTPM: 0.9
Min nTPM: 0.9
Sample A 0.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 0.0
Samples: 3

Max nTPM: 0.1
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.1
Midbrain
nTPM: 0.0
Samples: 3

Max nTPM: 0.1
Min nTPM: 0.0
Sample B Female 0.1
Sample C Male 0.0
Sample D Male 0.0
Periaqueductal gray
nTPM: 0.0
Samples: 3

Max nTPM: 0.0
Min nTPM: 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Superior colliculi
nTPM: 0.0
Samples: 4

Max nTPM: 0.1
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.1
Sample D Male 0.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 23.5
Samples: 4

Max nTPM: 27.4
Min nTPM: 19.3
Sample A 27.4
Sample B 26.5
Sample C 19.3
Sample D 20.8

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.6
Rat sample Sample description nTPM
Midbrain
nTPM: 0.6
Samples: 4

Max nTPM: 0.7
Min nTPM: 0.3
Sample A 0.7
Sample A 0.3
Sample A 0.7
Sample A 0.7

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