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BETA
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  • CLIP2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:67.7 nTPM
HPA Brain:160.6 nTPM
GTEx:67.7 nTPM
FANTOM5:86.3 Scaled Tags Per Million
Macaque:53.1 nTPM
Mouse:56.6 nTPM
Rat:49.9 nTPM
Pig:23.8 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 130
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 260
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

160.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 146.5
2586 Male, age 75, left hemisphere 217.2
2666 Male, age 74, left hemisphere 158.5
1830 Male, age 51, unknown 148.3
2828 Female, age 72, unknown 143.8
1833 Male, age 53, unknown 142.1
1827 Male, age 72, unknown 137.1
2411 Female, age 72, unknown 134.6
1870 Female, age 42, unknown 131.4
2019 Male, age 18, unknown 130.7
2219 Male, age 76, both hemispheres 121.0
Dorsal raphe nucleus
nTPM: 138.1
2016 Female, age 72, unknown 144.9
2750 Male, age 76, both hemispheres 144.7
1828 Male, age 53, unknown 143.5
2047 Male, age 72, unknown 140.5
2298 Female, age 72, unknown 117.1
Inferior colliculus
nTPM: 113.6
2849 Male, age 72, unknown 131.7
1890 Male, age 53, unknown 114.1
1848 Female, age 42, unknown 107.5
2097 Female, age 72, unknown 100.9
Median raphe nucleus
nTPM: 124.1
2220 Male, age 76, midline 124.1
Periaquaductal grey, anterior
nTPM: 140.0
2502 Female, age 75, unknown 152.1
1947 Male, age 18, unknown 139.3
1795 Male, age 51, unknown 128.8
Periaquaductal grey, dorsal
nTPM: 120.3
2850 Male, age 76, both hemispheres 127.5
1831 Male, age 72, unknown 122.5
1840 Male, age 53, unknown 117.5
2464 Female, age 72, unknown 113.6
Periaquaductal grey, lateral
nTPM: 121.5
2053 Male, age 18, unknown 128.9
2140 Male, age 76, both hemispheres 119.9
2272 Male, age 74, both hemispheres 115.7
Pretectal area
nTPM: 116.8
2407 Male, age 75, both hemispheres 157.7
2825 Male, age 18, unknown 134.0
1815 Male, age 53, unknown 120.2
2007 Male, age 72, unknown 119.0
2316 Male, age 76, right hemisphere 115.5
2273 Male, age 74, both hemispheres 114.5
1817 Female, age 42, unknown 112.0
1816 Male, age 51, unknown 107.5
2667 Female, age 75, unknown 104.6
2224 Female, age 72, unknown 101.0
1944 Female, age 72, unknown 98.9
Red nucleus
nTPM: 160.6
2584 Male, age 75, left hemisphere 206.0
1904 Male, age 53, unknown 166.0
2769 Male, age 72, unknown 166.0
2588 Male, age 74, left hemisphere 165.8
2725 Female, age 75, unknown 160.8
1865 Male, age 51, unknown 159.9
2227 Male, age 72, unknown 159.7
1821 Female, age 72, unknown 154.9
2823 Male, age 76, right hemisphere 154.5
2503 Female, age 72, unknown 150.0
1954 Female, age 42, unknown 143.9
2785 Male, age 18, unknown 140.0
Substantia nigra
nTPM: 146.3
2583 Male, age 75, right hemisphere 175.5
2699 Male, age 18, unknown 164.4
1916 Female, age 42, unknown 162.2
2665 Male, age 74, both hemispheres 158.8
1851 Male, age 51, unknown 155.0
2590 Female, age 75, unknown 148.9
1941 Male, age 53, unknown 146.8
2409 Female, age 72, unknown 124.3
1889 Female, age 72, unknown 118.7
2241 Male, age 72, unknown 108.4
Superior colliculus
nTPM: 132.3
2664 Male, age 75, both hemispheres 184.1
1995 Male, age 72, unknown 142.6
1913 Female, age 42, unknown 137.5
1839 Male, age 51, unknown 136.4
2587 Male, age 74, left hemisphere 130.7
2668 Female, age 75, unknown 128.6
1796 Male, age 53, unknown 124.4
1895 Male, age 76, right hemisphere 122.1
2261 Male, age 18, unknown 118.9
2087 Female, age 72, unknown 97.9
Ventral tegmental area
nTPM: 137.9
2223 Female, age 72, unknown 146.4
2410 Female, age 72, unknown 143.4
1942 Male, age 51, unknown 140.6
1915 Female, age 42, unknown 139.8
2021 Male, age 53, unknown 131.0
2218 Male, age 76, both hemispheres 126.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

67.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 67.7
Samples: 183

Max nTPM: 144.2
Min nTPM: 32.0
Std nTPM: 18.2
Median nTPM: 65.4
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 144.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 119.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 112.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 108.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 107.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 106.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 104.9
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 104.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 104.0
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 103.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 103.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 102.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 100.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 99.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 95.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 95.1
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 94.9
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 94.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 93.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 93.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 92.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 89.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 87.8
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 87.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 85.7
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 85.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 84.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 82.9
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 82.8
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 82.7
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 81.9
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 81.6
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 81.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 81.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.1
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 81.0
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 79.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 79.5
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 78.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 78.6
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 78.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 78.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 78.3
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 78.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 77.9
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 77.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 76.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 76.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 75.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 74.9
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 74.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 74.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 74.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 74.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 74.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 74.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 74.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 73.7
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 73.4
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 73.2
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 73.2
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 72.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 72.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 72.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 72.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 72.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 71.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 71.4
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 71.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 71.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 71.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 70.7
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 70.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 70.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 69.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 69.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 69.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 69.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 69.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 69.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 68.9
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 68.8
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 68.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 68.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 67.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 67.3
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 67.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 67.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 66.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 66.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 65.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 65.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 65.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 65.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 65.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 65.1
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 64.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 64.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 64.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 64.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 64.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 63.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 63.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 63.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 63.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 62.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 62.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 61.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 61.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 61.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 61.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 61.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 60.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 60.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 60.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 60.4
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 60.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 59.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 59.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 59.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 59.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 59.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 59.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 59.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 59.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 59.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 58.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 58.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 58.2
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 58.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 58.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 57.1
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 57.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 56.5
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 55.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 55.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 55.0
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 54.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 54.4
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 54.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 53.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 53.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 53.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 53.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 52.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 52.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 52.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 52.2
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 51.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 51.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 51.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 51.2
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 50.5
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 50.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 50.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 50.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 49.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 48.8
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 48.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 48.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 47.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 47.3
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 46.7
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 46.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 46.1
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 45.9
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 44.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 43.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 42.5
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 42.3
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 40.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 38.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 34.3
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 34.2
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 34.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 33.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 33.0
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 32.8
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 32.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 32.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

86.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 86.3
FF:10158-103A5 76 years, female 86.3

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

53.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 47.6
Samples: 1

Max nTPM: 47.6
Min nTPM: 47.6
Sample A 47.6
Midbrain
nTPM: 39.4
Samples: 1

Max nTPM: 39.4
Min nTPM: 39.4
Sample A 39.4
Superior colliculi
nTPM: 53.1
Samples: 1

Max nTPM: 53.1
Min nTPM: 53.1
Sample A 53.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 23.8
Samples: 3

Max nTPM: 27.2
Min nTPM: 17.5
Sample A Female 27.2
Sample B Female 17.5
Sample C Male 26.8
Midbrain
nTPM: 22.9
Samples: 3

Max nTPM: 28.8
Min nTPM: 19.7
Sample B Female 19.7
Sample C Male 28.8
Sample D Male 20.2
Periaqueductal gray
nTPM: 16.9
Samples: 3

Max nTPM: 17.7
Min nTPM: 15.3
Sample B Female 17.7
Sample C Male 17.7
Sample D Male 15.3
Superior colliculi
nTPM: 20.6
Samples: 4

Max nTPM: 27.1
Min nTPM: 11.1
Sample A Female 20.8
Sample B Female 11.1
Sample C Male 27.1
Sample D Male 23.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

56.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 56.6
Samples: 4

Max nTPM: 62.1
Min nTPM: 50.9
Sample A 50.9
Sample B 62.1
Sample C 58.2
Sample D 55.3

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.9
Rat sample Sample description nTPM
Midbrain
nTPM: 49.9
Samples: 4

Max nTPM: 52.3
Min nTPM: 47.9
Sample A 51.2
Sample A 52.3
Sample A 48.3
Sample A 47.9

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