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BETA
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  • EVOLUTION

  • H3-3B
EVOLUTIONARY URINARY BLADDER Show tissue menu
BRAIN35 EYE3 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT10 LIVER & GALLBLADDER2 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM8 BREAST & FEMALE REPRODUCTIVE SYSTEM7 MUSCLE & VASCULAR TISSUE11 CONNECTIVE & SOFT TISSUE11 SKIN3 BONE MARROW & LYMPHOID TISSUES6
Select an organ to show its tissues
AMYGDALA BASAL GANGLIA CAUDATE NUCLEUS CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CORPUS CALLOSUM DORSAL HIPPOCAMPUS DORSAL SPINAL CORD ENTORHINAL CORTEX HIPPOCAMPAL FORMATION
HYPOTHALAMUS INSULAR CORTEX MEDULLA OBLONGATA MIDBRAIN MOTOR CORTEX OCCIPITAL CORTEX OLFACTORY BULB PERIAQUEDUCTAL GRAY PONS PREFRONTAL CORTEX PUTAMEN RETROSPLENIAL CORTEX
SEPTUM SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI TEMPORAL CORTEX THALAMUS VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD
CORNEA LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (UPPER)
GALLBLADDER LIVER
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS PENIS PROSTATE SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX ENDOMETRIUM FALLOPIAN TUBE OVARY PLACENTA VAGINA
AORTA BLOOD VESSEL HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE DURA MATER EAR CARTILAGE JOINT CARTILAGE ORBITAL ADIPOSE TISSUE PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Kidney & Urinary bladder
Evolutionary methods
URINARY BLADDER - Expression summary
Protein expression
Urinary bladderi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

h
m
l
n
Urothelial cells: High
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:480.3 nTPM
HPA:477.7 nTPM
GTEx:480.3 nTPM
FANTOM5:515.8 Scaled Tags Per Million
Pig:0.5 nTPM
URINARY BLADDER - SINGLE CELL RNA EXPRESSION
Explore single cell type data

URINARY BLADDER - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

Antibody CAB037166Antibody CAB037187Antibody CAB037221
Urothelial cells HighHighHigh





URINARY BLADDER - PROTEINTALKS DB MS
Median intensity 1352935
Sample Intensity
Urinary bladder_01
1352935

URINARY BLADDER - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Average nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

477.7
overview
Male, age 74
Urinary bladder sample 264
nTPM: 440.3
Cell types%
Urothelial cells:
5

Smooth muscle cells:
60

Fibroblasts:
20

Endothelial cells:
10

Other cell types:
5

overview
Male, age 80
Urinary bladder sample 265
nTPM: 473.4
Cell types%
Urothelial cells:
10

Smooth muscle cells:
45

Fibroblasts:
15

Endothelial cells:
10

Other cell types:
20

N/A
Female, age 79
Urinary bladder sample 1597
nTPM: 618.7
N/A
Male, age 52
Urinary bladder sample 1598
nTPM: 378.7

URINARY BLADDER - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

480.3
GTEx sample id Sample description nTPM
Bladder
Average nTPM: 480.3
Samples: 77

Max nTPM: 940.4
Min nTPM: 221.6
Std nTPM: 144.9
Median nTPM: 486.5
GTEX-T6MO-0926-SM-GPRWN 40-49 years, female 940.4
GTEX-OOBK-1926-SM-HAUZL 40-49 years, male 858.0
GTEX-T5JW-1026-SM-EZ6LR 20-29 years, female 823.8
GTEX-S4UY-0926-SM-4AD6O 40-49 years, female 791.5
GTEX-T8EM-1726-SM-GPRWO 40-49 years, male 677.1
GTEX-S32W-1126-SM-4AD5V 50-59 years, female 667.0
GTEX-OIZH-1926-SM-GPRXO 50-59 years, male 663.9
GTEX-S3XE-1226-SM-4AD4L 50-59 years, male 655.9
GTEX-S7SF-1126-SM-GQ1CH 20-29 years, female 637.2
GTEX-U3ZN-1226-SM-4DXUD 30-39 years, female 635.8
GTEX-OXRK-1926-SM-GRR1N 50-59 years, female 629.0
GTEX-QXCU-2226-SM-GPI87 50-59 years, male 617.3
GTEX-RUSQ-1326-SM-GQ1EA 50-59 years, male 600.8
GTEX-R55G-1326-SM-HAUYU 40-49 years, female 599.9
GTEX-S4Q7-0926-SM-4AD5D 20-29 years, male 595.8
GTEX-PX3G-1926-SM-GQ1ED 20-29 years, female 588.3
GTEX-O5YT-1926-SM-H6Q82 20-29 years, male 580.2
GTEX-N7MT-1826-SM-GQ1C9 60-69 years, female 579.6
GTEX-QDVN-1426-SM-GPRWL 50-59 years, male 578.8
GTEX-PW2O-1026-SM-GPRWA 20-29 years, male 573.2
GTEX-QV31-0926-SM-GQ1C6 30-39 years, male 570.4
GTEX-QCQG-0826-SM-GPI8H 50-59 years, female 568.3
GTEX-P78B-2126-SM-GQ1C3 40-49 years, female 554.2
GTEX-OIZI-1926-SM-H7OGY 40-49 years, male 535.2
GTEX-P4PQ-1926-SM-GRR14 60-69 years, male 535.2
GTEX-P44H-2226-SM-E9U4P 40-49 years, male 533.2
GTEX-SNOS-0526-SM-4DM54 40-49 years, male 529.5
GTEX-Q2AH-1326-SM-GPRWF 40-49 years, male 528.1
GTEX-R53T-1426-SM-H7OG3 50-59 years, female 527.3
GTEX-QDT8-2826-SM-GOQYY 30-39 years, female 511.6
GTEX-OIZF-1926-SM-7PBZS 60-69 years, male 507.8
GTEX-PWN1-1926-SM-HAUZN 40-49 years, female 506.5
GTEX-T6MN-2226-SM-EVYAM 50-59 years, male 503.5
GTEX-OHPL-1926-SM-HAV18 60-69 years, female 503.4
GTEX-PWCY-1126-SM-H7OGX 20-29 years, female 503.4
GTEX-PLZ6-1026-SM-GQ1C8 30-39 years, male 492.6
GTEX-P4PP-1926-SM-HAUZM 30-39 years, female 489.2
GTEX-S95S-0626-SM-EZ6L8 60-69 years, male 486.6
GTEX-SNMC-0826-SM-4DM66 20-29 years, male 486.5
GTEX-QEG4-2126-SM-GQ1CE 30-39 years, male 480.0
GTEX-QLQ7-1226-SM-GOQYE 60-69 years, male 475.7
GTEX-T5JC-1126-SM-GPIA1 20-29 years, male 473.6
GTEX-QMRM-1326-SM-HAUYS 50-59 years, male 454.9
GTEX-NPJ8-1126-SM-GNTAI 40-49 years, male 448.7
GTEX-U3ZH-0826-SM-H6Q7I 30-39 years, male 442.7
GTEX-QEG5-2326-SM-GRR2Z 20-29 years, male 439.8
GTEX-Q2AI-1026-SM-GRR3I 40-49 years, male 437.5
GTEX-REY6-2026-SM-GPRYL 60-69 years, male 426.7
GTEX-P4QS-1926-SM-GQ1BY 60-69 years, male 423.4
GTEX-RNOR-2126-SM-EXURR 50-59 years, female 402.8
GTEX-QDVJ-1526-SM-GPI84 50-59 years, male 387.5
GTEX-QV44-1426-SM-GPI8D 50-59 years, male 383.5
GTEX-TKQ2-0526-SM-GRR15 50-59 years, male 381.4
GTEX-RWSA-2126-SM-H7OG7 40-49 years, male 378.0
GTEX-S33H-1926-SM-EYYVH 30-39 years, male 377.3
GTEX-N7MS-2126-SM-GRR2X 60-69 years, male 376.2
GTEX-R45C-2426-SM-HL11G 60-69 years, female 371.9
GTEX-RWS6-1426-SM-GPRWQ 60-69 years, female 369.5
GTEX-RN64-2426-SM-EZ6L2 50-59 years, male 365.5
GTEX-S4P3-0826-SM-H7OF3 50-59 years, female 364.4
GTEX-SUCS-1226-SM-GPI9A 70-79 years, male 362.7
GTEX-OHPK-1926-SM-H7OF2 50-59 years, female 358.5
GTEX-POMQ-0926-SM-H6Q6H 20-29 years, female 353.6
GTEX-QLQW-0826-SM-H7OG2 30-39 years, male 347.5
GTEX-P4QT-1926-SM-HAUYQ 50-59 years, female 343.0
GTEX-OOBJ-1926-SM-GRR1P 60-69 years, male 319.7
GTEX-T2IS-2526-SM-GRR23 20-29 years, female 318.6
GTEX-Q734-1226-SM-GRR21 40-49 years, female 316.2
GTEX-U3ZM-0826-SM-4DXU6 40-49 years, male 309.1
GTEX-PLZ5-1326-SM-GQ1C2 50-59 years, male 288.8
GTEX-QEL4-1826-SM-EZ6KU 50-59 years, male 287.1
GTEX-OHPM-1926-SM-H7OG1 50-59 years, male 277.3
GTEX-TMMY-1526-SM-4DXST 40-49 years, female 275.7
GTEX-RM2N-1026-SM-GOQY8 50-59 years, male 264.9
GTEX-U4B1-1226-SM-4DXT7 40-49 years, male 264.9
GTEX-SE5C-1026-SM-4BRUG 40-49 years, female 250.6
GTEX-R55C-1226-SM-GOQY7 40-49 years, male 221.6
Show allShow less

URINARY BLADDER - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

515.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Bladder
Scaled Tags Per Million: 515.8
FF:10011-101C2 55,58,79 years, mixed 515.8

URINARY BLADDER - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.5
Pig sample Sample description nTPM
Urinary bladder
nTPM: 0.5
Samples: 4

Max nTPM: 0.8
Min nTPM: 0.3
Sample A Female 0.3
Sample B Female 0.8
Sample C Male 0.5
Sample D Male 0.3

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