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BETA
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  • MTSS2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:257.8 nTPM
HPA Brain:670.2 nTPM
GTEx:257.8 nTPM
FANTOM5:385.0 Scaled Tags Per Million
Macaque:189.1 nTPM
Mouse:197.5 nTPM
Rat:148.7 nTPM
Pig:140.6 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 70
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 480
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

670.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 536.0
2828 Female, age 72, unknown 781.1
2586 Male, age 75, left hemisphere 772.4
2219 Male, age 76, both hemispheres 632.3
2666 Male, age 74, left hemisphere 625.0
1827 Male, age 72, unknown 503.2
1833 Male, age 53, unknown 447.5
1870 Female, age 42, unknown 440.6
1830 Male, age 51, unknown 408.6
2019 Male, age 18, unknown 407.9
2411 Female, age 72, unknown 342.0
Dorsal raphe nucleus
nTPM: 529.3
2016 Female, age 72, unknown 684.5
1828 Male, age 53, unknown 596.7
2047 Male, age 72, unknown 517.7
2298 Female, age 72, unknown 450.0
2750 Male, age 76, both hemispheres 397.4
Inferior colliculus
nTPM: 469.0
2849 Male, age 72, unknown 571.4
1848 Female, age 42, unknown 479.5
1890 Male, age 53, unknown 462.3
2097 Female, age 72, unknown 362.7
Median raphe nucleus
nTPM: 402.5
2220 Male, age 76, midline 402.5
Periaquaductal grey, anterior
nTPM: 571.4
1795 Male, age 51, unknown 702.6
2502 Female, age 75, unknown 590.1
1947 Male, age 18, unknown 421.5
Periaquaductal grey, dorsal
nTPM: 641.8
2850 Male, age 76, both hemispheres 807.6
1831 Male, age 72, unknown 695.6
1840 Male, age 53, unknown 615.4
2464 Female, age 72, unknown 448.7
Periaquaductal grey, lateral
nTPM: 670.2
2053 Male, age 18, unknown 748.6
2140 Male, age 76, both hemispheres 746.5
2272 Male, age 74, both hemispheres 515.4
Pretectal area
nTPM: 579.9
2316 Male, age 76, right hemisphere 664.9
2407 Male, age 75, both hemispheres 651.9
2825 Male, age 18, unknown 619.4
2667 Female, age 75, unknown 617.8
1815 Male, age 53, unknown 590.5
1944 Female, age 72, unknown 582.8
1816 Male, age 51, unknown 569.2
2273 Male, age 74, both hemispheres 552.5
2224 Female, age 72, unknown 535.4
1817 Female, age 42, unknown 514.1
2007 Male, age 72, unknown 480.4
Red nucleus
nTPM: 496.5
2769 Male, age 72, unknown 547.4
2503 Female, age 72, unknown 545.9
2584 Male, age 75, left hemisphere 526.4
2823 Male, age 76, right hemisphere 524.6
2588 Male, age 74, left hemisphere 520.2
2227 Male, age 72, unknown 503.8
1904 Male, age 53, unknown 499.8
1865 Male, age 51, unknown 495.6
2785 Male, age 18, unknown 469.9
1954 Female, age 42, unknown 448.8
2725 Female, age 75, unknown 447.9
1821 Female, age 72, unknown 428.0
Substantia nigra
nTPM: 544.1
2699 Male, age 18, unknown 874.3
2665 Male, age 74, both hemispheres 706.4
2583 Male, age 75, right hemisphere 632.1
1916 Female, age 42, unknown 549.6
1851 Male, age 51, unknown 529.2
2590 Female, age 75, unknown 473.1
1889 Female, age 72, unknown 459.4
1941 Male, age 53, unknown 453.2
2409 Female, age 72, unknown 417.1
2241 Male, age 72, unknown 346.7
Superior colliculus
nTPM: 588.8
2664 Male, age 75, both hemispheres 852.1
1995 Male, age 72, unknown 701.0
2668 Female, age 75, unknown 625.5
1913 Female, age 42, unknown 623.3
1796 Male, age 53, unknown 584.2
2587 Male, age 74, left hemisphere 554.8
2087 Female, age 72, unknown 552.5
1839 Male, age 51, unknown 545.8
2261 Male, age 18, unknown 503.0
1895 Male, age 76, right hemisphere 345.7
Ventral tegmental area
nTPM: 519.2
2021 Male, age 53, unknown 587.5
1942 Male, age 51, unknown 552.1
1915 Female, age 42, unknown 534.2
2218 Male, age 76, both hemispheres 491.2
2223 Female, age 72, unknown 480.2
2410 Female, age 72, unknown 470.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

257.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 257.8
Samples: 183

Max nTPM: 467.5
Min nTPM: 67.5
Std nTPM: 87.0
Median nTPM: 249.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 467.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 462.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 457.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 455.5
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 432.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 430.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 422.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 412.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 411.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 405.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 404.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 403.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 394.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 394.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 390.9
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 385.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 384.8
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 378.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 375.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 375.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 375.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 371.2
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 368.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 363.5
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 361.6
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 361.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 359.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 358.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 355.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 351.3
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 347.9
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 344.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 340.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 338.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 335.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 332.5
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 332.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 330.5
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 330.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 327.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 326.6
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 324.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 323.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 323.0
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 322.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 321.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 320.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 320.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 319.7
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 318.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 316.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 315.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 312.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 311.9
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 311.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 308.6
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 307.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 306.0
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 304.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 299.5
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 296.7
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 292.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 291.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 291.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 291.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 289.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 286.9
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 283.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 283.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 281.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 280.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 277.4
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 276.8
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 272.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 270.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 269.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 265.8
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 265.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 264.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 262.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 261.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 261.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 260.6
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 260.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 259.8
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 259.4
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 258.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 256.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 255.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 250.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 250.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 249.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 249.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 247.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 246.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 245.0
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 245.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 244.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 244.5
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 243.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 243.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 241.7
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 241.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 240.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 238.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 237.2
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 234.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 231.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 231.5
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 231.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 228.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 227.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 227.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 226.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 224.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 222.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 221.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 220.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 219.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 219.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 217.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 216.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 210.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 208.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 206.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 205.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 204.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 203.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 202.9
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 202.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 200.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 197.6
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 197.0
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 195.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 195.1
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 194.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 194.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 187.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 184.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 182.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 182.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 179.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 178.6
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 178.4
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 178.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 178.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 176.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 175.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 175.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 173.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 173.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 173.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 171.4
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 171.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 170.1
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 169.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 169.4
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 167.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 166.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 162.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 162.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 160.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 159.0
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 156.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 155.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 152.9
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 149.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 142.2
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 139.2
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 137.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 137.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 133.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 132.1
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 125.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 109.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 109.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 109.6
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 106.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 103.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 101.7
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 81.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 80.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 67.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

385.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 385.0
FF:10158-103A5 76 years, female 385.0

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

189.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 134.2
Samples: 1

Max nTPM: 134.2
Min nTPM: 134.2
Sample A 134.2
Midbrain
nTPM: 168.9
Samples: 1

Max nTPM: 168.9
Min nTPM: 168.9
Sample A 168.9
Superior colliculi
nTPM: 189.1
Samples: 1

Max nTPM: 189.1
Min nTPM: 189.1
Sample A 189.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

140.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 138.0
Samples: 3

Max nTPM: 159.3
Min nTPM: 117.8
Sample A Female 136.8
Sample B Female 117.8
Sample C Male 159.3
Midbrain
nTPM: 140.6
Samples: 3

Max nTPM: 144.6
Min nTPM: 138.4
Sample B Female 138.4
Sample C Male 144.6
Sample D Male 138.7
Periaqueductal gray
nTPM: 140.4
Samples: 3

Max nTPM: 149.0
Min nTPM: 127.4
Sample B Female 144.9
Sample C Male 149.0
Sample D Male 127.4
Superior colliculi
nTPM: 128.5
Samples: 4

Max nTPM: 157.1
Min nTPM: 78.6
Sample A Female 139.1
Sample B Female 78.6
Sample C Male 139.0
Sample D Male 157.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

197.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 197.5
Samples: 4

Max nTPM: 218.0
Min nTPM: 187.0
Sample A 196.7
Sample B 218.0
Sample C 188.3
Sample D 187.0

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

148.7
Rat sample Sample description nTPM
Midbrain
nTPM: 148.8
Samples: 4

Max nTPM: 156.5
Min nTPM: 142.8
Sample A 151.5
Sample A 156.5
Sample A 144.2
Sample A 142.8

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