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BETA
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  • EEF1A1
EVOLUTIONARY URINARY BLADDER Show tissue menu
BRAIN55 EYE3 ENDOCRINE TISSUES4 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER2 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM6 BREAST & FEMALE REPRODUCTIVE SYSTEM9 MUSCLE & VASCULAR TISSUE11 CONNECTIVE & SOFT TISSUE14 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CLAUSTRUM CUNEUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI
MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREOPTIC AREA
PUTAMEN SEPTUM SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS THALAMUS VENTRAL SPINAL CORD WHITE MATTER
CORNEA LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
DUCTUS DEFERENS EPIDIDYMIS PENIS PROSTATE SEMINAL VESICLE TESTIS
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Kidney & Urinary bladder
Evolutionary methods
URINARY BLADDER - Expression summary
Protein expression
Urinary bladderi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

h
m
l
n
Urothelial cells: High
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:6595.0 nTPM
HPA:6540.1 nTPM
GTEx:6595.0 nTPM
FANTOM5:50.5 Scaled Tags Per Million
Macaque:5625.3 nTPM
URINARY BLADDER - SINGLE CELL RNA EXPRESSION
Explore single cell type data

URINARY BLADDER - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

Antibody HPA051759Antibody HPA056990
Urothelial cells HighMedium





URINARY BLADDER - PROTEINTALKS DB MS
Median intensity 931161
Sample Intensity
Urinary bladder_01
931161

URINARY BLADDER - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Average nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6540.1
overview
Male, age 74
Urinary bladder sample 264
nTPM: 6293.2
Cell types%
Urothelial cells:
5

Smooth muscle cells:
60

Fibroblasts:
20

Endothelial cells:
10

Other cell types:
5

overview
Male, age 80
Urinary bladder sample 265
nTPM: 6278.5
Cell types%
Urothelial cells:
10

Smooth muscle cells:
45

Fibroblasts:
15

Endothelial cells:
10

Other cell types:
20

N/A
Female, age 79
Urinary bladder sample 1597
nTPM: 6437.5
N/A
Male, age 52
Urinary bladder sample 1598
nTPM: 7151.4

URINARY BLADDER - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6595.0
GTEx sample id Sample description nTPM
Bladder
Average nTPM: 6595.0
Samples: 77

Max nTPM: 9548.4
Min nTPM: 4437.8
Std nTPM: 1029.6
Median nTPM: 6579.4
GTEX-T5JC-1126-SM-GPIA1 20-29 years, male 9548.4
GTEX-NPJ8-1126-SM-GNTAI 40-49 years, male 8940.8
GTEX-T6MO-0926-SM-GPRWN 40-49 years, female 8284.2
GTEX-TMMY-1526-SM-4DXST 40-49 years, female 8229.6
GTEX-OIZF-1926-SM-7PBZS 60-69 years, male 8199.3
GTEX-P44H-2226-SM-E9U4P 40-49 years, male 8180.0
GTEX-PLZ6-1026-SM-GQ1C8 30-39 years, male 8090.8
GTEX-QDT8-2826-SM-GOQYY 30-39 years, female 7966.2
GTEX-Q2AH-1326-SM-GPRWF 40-49 years, male 7934.2
GTEX-S4P3-0826-SM-H7OF3 50-59 years, female 7886.1
GTEX-Q734-1226-SM-GRR21 40-49 years, female 7855.1
GTEX-QV31-0926-SM-GQ1C6 30-39 years, male 7637.9
GTEX-P4QS-1926-SM-GQ1BY 60-69 years, male 7595.4
GTEX-REY6-2026-SM-GPRYL 60-69 years, male 7529.1
GTEX-R55C-1226-SM-GOQY7 40-49 years, male 7444.0
GTEX-OHPK-1926-SM-H7OF2 50-59 years, female 7441.0
GTEX-S32W-1126-SM-4AD5V 50-59 years, female 7338.2
GTEX-T2IS-2526-SM-GRR23 20-29 years, female 7329.2
GTEX-R45C-2426-SM-HL11G 60-69 years, female 7318.9
GTEX-OHPL-1926-SM-HAV18 60-69 years, female 7289.9
GTEX-OOBK-1926-SM-HAUZL 40-49 years, male 7197.6
GTEX-P78B-2126-SM-GQ1C3 40-49 years, female 7161.2
GTEX-OXRK-1926-SM-GRR1N 50-59 years, female 7154.4
GTEX-QDVJ-1526-SM-GPI84 50-59 years, male 7137.1
GTEX-RWS6-1426-SM-GPRWQ 60-69 years, female 7116.6
GTEX-QMRM-1326-SM-HAUYS 50-59 years, male 7112.4
GTEX-T8EM-1726-SM-GPRWO 40-49 years, male 7097.3
GTEX-P4PP-1926-SM-HAUZM 30-39 years, female 7084.6
GTEX-OIZH-1926-SM-GPRXO 50-59 years, male 7080.1
GTEX-TKQ2-0526-SM-GRR15 50-59 years, male 7013.7
GTEX-SUCS-1226-SM-GPI9A 70-79 years, male 6931.0
GTEX-P4PQ-1926-SM-GRR14 60-69 years, male 6913.1
GTEX-S3XE-1226-SM-4AD4L 50-59 years, male 6839.1
GTEX-T5JW-1026-SM-EZ6LR 20-29 years, female 6736.0
GTEX-RN64-2426-SM-EZ6L2 50-59 years, male 6712.0
GTEX-R55G-1326-SM-HAUYU 40-49 years, female 6657.2
GTEX-QLQ7-1226-SM-GOQYE 60-69 years, male 6634.9
GTEX-OOBJ-1926-SM-GRR1P 60-69 years, male 6630.4
GTEX-PLZ5-1326-SM-GQ1C2 50-59 years, male 6579.4
GTEX-QEL4-1826-SM-EZ6KU 50-59 years, male 6570.8
GTEX-U3ZM-0826-SM-4DXU6 40-49 years, male 6494.0
GTEX-Q2AI-1026-SM-GRR3I 40-49 years, male 6482.7
GTEX-OHPM-1926-SM-H7OG1 50-59 years, male 6472.6
GTEX-QDVN-1426-SM-GPRWL 50-59 years, male 6443.7
GTEX-QEG5-2326-SM-GRR2Z 20-29 years, male 6331.5
GTEX-T6MN-2226-SM-EVYAM 50-59 years, male 6271.7
GTEX-N7MS-2126-SM-GRR2X 60-69 years, male 6264.6
GTEX-U4B1-1226-SM-4DXT7 40-49 years, male 6208.5
GTEX-RNOR-2126-SM-EXURR 50-59 years, female 6140.1
GTEX-SE5C-1026-SM-4BRUG 40-49 years, female 6107.1
GTEX-OIZI-1926-SM-H7OGY 40-49 years, male 6099.6
GTEX-S4UY-0926-SM-4AD6O 40-49 years, female 6008.9
GTEX-PWCY-1126-SM-H7OGX 20-29 years, female 5950.2
GTEX-S4Q7-0926-SM-4AD5D 20-29 years, male 5870.8
GTEX-O5YT-1926-SM-H6Q82 20-29 years, male 5854.5
GTEX-QV44-1426-SM-GPI8D 50-59 years, male 5829.3
GTEX-P4QT-1926-SM-HAUYQ 50-59 years, female 5790.8
GTEX-PWN1-1926-SM-HAUZN 40-49 years, female 5785.2
GTEX-RM2N-1026-SM-GOQY8 50-59 years, male 5761.4
GTEX-N7MT-1826-SM-GQ1C9 60-69 years, female 5743.7
GTEX-QCQG-0826-SM-GPI8H 50-59 years, female 5584.3
GTEX-S95S-0626-SM-EZ6L8 60-69 years, male 5563.8
GTEX-R53T-1426-SM-H7OG3 50-59 years, female 5526.5
GTEX-RWSA-2126-SM-H7OG7 40-49 years, male 5515.7
GTEX-PX3G-1926-SM-GQ1ED 20-29 years, female 5483.0
GTEX-S33H-1926-SM-EYYVH 30-39 years, male 5449.0
GTEX-SNOS-0526-SM-4DM54 40-49 years, male 5443.3
GTEX-QXCU-2226-SM-GPI87 50-59 years, male 5415.1
GTEX-PW2O-1026-SM-GPRWA 20-29 years, male 5407.5
GTEX-U3ZN-1226-SM-4DXUD 30-39 years, female 5363.3
GTEX-QEG4-2126-SM-GQ1CE 30-39 years, male 5362.5
GTEX-U3ZH-0826-SM-H6Q7I 30-39 years, male 5219.2
GTEX-RUSQ-1326-SM-GQ1EA 50-59 years, male 5046.3
GTEX-QLQW-0826-SM-H7OG2 30-39 years, male 5020.6
GTEX-POMQ-0926-SM-H6Q6H 20-29 years, female 4956.1
GTEX-S7SF-1126-SM-GQ1CH 20-29 years, female 4710.9
GTEX-SNMC-0826-SM-4DM66 20-29 years, male 4437.8
Show allShow less

URINARY BLADDER - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

50.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Bladder
Scaled Tags Per Million: 50.5
FF:10011-101C2 55,58,79 years, mixed 50.5

URINARY BLADDER - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

5625.3
Macaque sample Sample description nTPM
Urinary bladder
nTPM: 5625.3
Samples: 3

Max nTPM: 5773.8
Min nTPM: 5540.7
Sample A 5773.8
Sample B 5540.7
Sample C 5561.5

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