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BETA
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  • RPS14
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:887.9 nTPM
HPA Brain:364.8 nTPM
GTEx:887.9 nTPM
FANTOM5:33.4 Scaled Tags Per Million
Macaque:12.8 nTPM
Mouse:689.8 nTPM
Pig:703.8 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 180
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 380
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

364.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 340.8
2411 Female, age 72, unknown 379.8
2666 Male, age 74, left hemisphere 371.5
2586 Male, age 75, left hemisphere 366.0
1870 Female, age 42, unknown 352.9
2828 Female, age 72, unknown 333.1
2219 Male, age 76, both hemispheres 332.2
1833 Male, age 53, unknown 331.6
1827 Male, age 72, unknown 323.4
1830 Male, age 51, unknown 313.8
2019 Male, age 18, unknown 303.3
Dorsal raphe nucleus
nTPM: 337.2
2016 Female, age 72, unknown 371.3
2298 Female, age 72, unknown 357.1
1828 Male, age 53, unknown 325.7
2750 Male, age 76, both hemispheres 321.5
2047 Male, age 72, unknown 310.2
Inferior colliculus
nTPM: 315.4
1890 Male, age 53, unknown 332.6
2849 Male, age 72, unknown 313.2
2097 Female, age 72, unknown 310.6
1848 Female, age 42, unknown 305.0
Median raphe nucleus
nTPM: 313.6
2220 Male, age 76, midline 313.6
Periaquaductal grey, anterior
nTPM: 336.2
2502 Female, age 75, unknown 384.7
1795 Male, age 51, unknown 317.3
1947 Male, age 18, unknown 306.4
Periaquaductal grey, dorsal
nTPM: 328.9
1840 Male, age 53, unknown 352.5
1831 Male, age 72, unknown 331.2
2464 Female, age 72, unknown 321.9
2850 Male, age 76, both hemispheres 309.8
Periaquaductal grey, lateral
nTPM: 311.2
2053 Male, age 18, unknown 371.4
2140 Male, age 76, both hemispheres 292.9
2272 Male, age 74, both hemispheres 269.3
Pretectal area
nTPM: 301.9
1815 Male, age 53, unknown 333.7
2224 Female, age 72, unknown 331.3
2825 Male, age 18, unknown 324.2
1817 Female, age 42, unknown 319.5
2316 Male, age 76, right hemisphere 317.6
2407 Male, age 75, both hemispheres 295.0
2007 Male, age 72, unknown 292.2
1944 Female, age 72, unknown 284.5
2273 Male, age 74, both hemispheres 282.2
1816 Male, age 51, unknown 273.7
2667 Female, age 75, unknown 267.3
Red nucleus
nTPM: 355.7
2503 Female, age 72, unknown 419.3
1865 Male, age 51, unknown 410.2
1821 Female, age 72, unknown 394.9
1904 Male, age 53, unknown 377.8
2769 Male, age 72, unknown 366.5
2227 Male, age 72, unknown 362.0
2725 Female, age 75, unknown 357.0
2584 Male, age 75, left hemisphere 338.6
2588 Male, age 74, left hemisphere 338.5
1954 Female, age 42, unknown 330.4
2785 Male, age 18, unknown 292.6
2823 Male, age 76, right hemisphere 279.9
Substantia nigra
nTPM: 364.8
2699 Male, age 18, unknown 459.4
2665 Male, age 74, both hemispheres 432.4
1851 Male, age 51, unknown 430.3
1916 Female, age 42, unknown 368.1
2409 Female, age 72, unknown 361.2
2241 Male, age 72, unknown 340.5
2590 Female, age 75, unknown 337.3
1889 Female, age 72, unknown 327.7
2583 Male, age 75, right hemisphere 296.9
1941 Male, age 53, unknown 294.4
Superior colliculus
nTPM: 337.1
2587 Male, age 74, left hemisphere 405.0
1913 Female, age 42, unknown 395.5
1995 Male, age 72, unknown 390.4
2668 Female, age 75, unknown 346.2
1839 Male, age 51, unknown 332.1
1796 Male, age 53, unknown 330.2
2664 Male, age 75, both hemispheres 315.1
2261 Male, age 18, unknown 298.8
1895 Male, age 76, right hemisphere 283.1
2087 Female, age 72, unknown 274.7
Ventral tegmental area
nTPM: 361.7
1915 Female, age 42, unknown 408.1
2410 Female, age 72, unknown 394.8
2223 Female, age 72, unknown 380.6
2021 Male, age 53, unknown 352.0
1942 Male, age 51, unknown 328.3
2218 Male, age 76, both hemispheres 306.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

887.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 887.9
Samples: 183

Max nTPM: 2357.1
Min nTPM: 351.7
Std nTPM: 322.0
Median nTPM: 807.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2357.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1819.7
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 1687.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1600.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1596.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1585.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1561.3
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 1556.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1545.6
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 1541.4
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 1524.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1499.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1481.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1441.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 1399.0
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 1389.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1375.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1326.2
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 1308.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1285.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1283.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1282.3
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 1276.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1274.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 1255.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1244.6
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 1240.5
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 1205.8
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 1200.2
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 1196.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 1183.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1182.7
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 1177.4
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 1176.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1159.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1158.2
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 1144.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1137.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1134.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1132.9
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 1122.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1114.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1107.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1103.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1086.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1080.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 1067.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1066.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1065.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1053.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1039.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1035.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1030.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1013.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1007.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1000.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 999.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 998.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 984.7
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 975.3
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 967.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 965.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 964.0
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 963.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 957.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 951.1
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 942.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 930.4
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 930.0
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 928.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 927.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 923.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 916.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 903.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 895.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 891.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 889.6
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 883.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 880.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 870.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 869.5
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 865.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 861.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 843.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 838.0
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 831.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 830.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 827.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 823.4
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 814.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 810.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 807.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 798.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 797.5
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 784.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 783.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 781.4
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 779.7
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 773.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 771.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 768.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 765.1
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 764.2
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 760.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 757.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 755.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 753.7
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 749.4
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 749.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 747.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 745.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 745.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 740.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 736.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 736.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 733.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 732.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 730.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 724.0
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 722.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 719.0
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 716.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 706.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 706.0
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 702.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 681.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 681.4
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 679.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 676.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 673.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 670.8
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 670.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 666.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 665.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 664.4
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 650.4
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 649.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 645.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 639.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 636.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 635.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 633.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 631.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 628.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 626.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 622.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 613.1
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 611.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 610.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 610.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 609.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 606.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 603.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 591.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 575.1
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 572.8
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 566.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 566.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 557.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 556.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 555.3
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 553.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 550.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 549.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 547.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 546.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 544.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 535.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 535.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 516.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 510.4
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 504.7
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 501.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 498.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 490.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 486.5
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 478.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 474.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 418.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 416.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 415.0
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 408.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 351.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

33.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 33.4
FF:10158-103A5 76 years, female 33.4

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.8
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 12.1
Samples: 1

Max nTPM: 12.1
Min nTPM: 12.1
Sample A 12.1
Midbrain
nTPM: 12.8
Samples: 1

Max nTPM: 12.8
Min nTPM: 12.8
Sample A 12.8
Superior colliculi
nTPM: 11.0
Samples: 1

Max nTPM: 11.0
Min nTPM: 11.0
Sample A 11.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

703.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 703.8
Samples: 3

Max nTPM: 823.2
Min nTPM: 592.8
Sample A Female 823.2
Sample B Female 695.5
Sample C Male 592.8
Midbrain
nTPM: 580.3
Samples: 3

Max nTPM: 669.6
Min nTPM: 497.3
Sample B Female 669.6
Sample C Male 574.0
Sample D Male 497.3
Periaqueductal gray
nTPM: 522.7
Samples: 3

Max nTPM: 581.0
Min nTPM: 482.2
Sample B Female 504.9
Sample C Male 581.0
Sample D Male 482.2
Superior colliculi
nTPM: 693.0
Samples: 4

Max nTPM: 823.9
Min nTPM: 602.4
Sample A Female 823.9
Sample B Female 709.1
Sample C Male 636.7
Sample D Male 602.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

689.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 689.8
Samples: 4

Max nTPM: 894.0
Min nTPM: 565.2
Sample A 708.9
Sample B 894.0
Sample C 565.2
Sample D 591.2

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