MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:20.9 nTPM
HPA Brain:33.9 nTPM
GTEx:20.9 nTPM
FANTOM5:1.7 Scaled Tags Per Million
Pig:48.1 nTPM
Mouse:51.5 nTPM
Allen mouse:2.9 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 33.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 29.3
2586 Male, age 75, left hemisphere 39.1
2219 Male, age 76, both hemispheres 34.6
2019 Male, age 18, unknown 34.2
1827 Male, age 72, unknown 31.6
2828 Female, age 72, unknown 30.6
2666 Male, age 74, left hemisphere 27.9
2411 Female, age 72, unknown 26.4
1833 Male, age 53, unknown 23.7
1870 Female, age 42, unknown 22.5
1830 Male, age 51, unknown 22.3
Dorsal raphe nucleus
nTPM: 26.4
2298 Female, age 72, unknown 31.1
2047 Male, age 72, unknown 29.8
1828 Male, age 53, unknown 25.3
2750 Male, age 76, both hemispheres 24.6
2016 Female, age 72, unknown 21.1
Inferior colliculus
nTPM: 26.9
2097 Female, age 72, unknown 32.1
1890 Male, age 53, unknown 28.2
1848 Female, age 42, unknown 25.1
2849 Male, age 72, unknown 22.1
Median raphe nucleus
nTPM: 26.4
2220 Male, age 76, midline 26.4
Periaquaductal grey, anterior
nTPM: 33.9
1795 Male, age 51, unknown 36.2
2502 Female, age 75, unknown 32.7
1947 Male, age 18, unknown 32.6
Periaquaductal grey, dorsal
nTPM: 23.5
1831 Male, age 72, unknown 25.5
2464 Female, age 72, unknown 25.2
1840 Male, age 53, unknown 24.2
2850 Male, age 76, both hemispheres 19.0
Periaquaductal grey, lateral
nTPM: 22.0
2140 Male, age 76, both hemispheres 22.6
2053 Male, age 18, unknown 22.2
2272 Male, age 74, both hemispheres 21.2
Pretectal area
nTPM: 32.7
2007 Male, age 72, unknown 48.1
1816 Male, age 51, unknown 45.8
1944 Female, age 72, unknown 42.1
1817 Female, age 42, unknown 38.8
1815 Male, age 53, unknown 34.6
2667 Female, age 75, unknown 32.3
2407 Male, age 75, both hemispheres 26.4
2224 Female, age 72, unknown 24.6
2273 Male, age 74, both hemispheres 23.3
2825 Male, age 18, unknown 22.0
2316 Male, age 76, right hemisphere 21.6
Red nucleus
nTPM: 26.0
2785 Male, age 18, unknown 35.1
2588 Male, age 74, left hemisphere 34.0
2584 Male, age 75, left hemisphere 32.1
2725 Female, age 75, unknown 25.5
2503 Female, age 72, unknown 24.8
2769 Male, age 72, unknown 24.6
1904 Male, age 53, unknown 24.4
2227 Male, age 72, unknown 24.2
1821 Female, age 72, unknown 23.8
1954 Female, age 42, unknown 21.5
1865 Male, age 51, unknown 20.8
2823 Male, age 76, right hemisphere 20.6
Substantia nigra
nTPM: 30.6
1916 Female, age 42, unknown 40.3
2665 Male, age 74, both hemispheres 39.7
1889 Female, age 72, unknown 35.4
1851 Male, age 51, unknown 33.7
1941 Male, age 53, unknown 33.7
2409 Female, age 72, unknown 25.9
2590 Female, age 75, unknown 25.9
2583 Male, age 75, right hemisphere 25.3
2241 Male, age 72, unknown 23.9
2699 Male, age 18, unknown 21.9
Superior colliculus
nTPM: 29.0
2087 Female, age 72, unknown 39.1
2261 Male, age 18, unknown 34.9
1796 Male, age 53, unknown 33.3
2668 Female, age 75, unknown 33.1
2664 Male, age 75, both hemispheres 32.5
2587 Male, age 74, left hemisphere 24.8
1895 Male, age 76, right hemisphere 24.0
1839 Male, age 51, unknown 23.3
1913 Female, age 42, unknown 22.6
1995 Male, age 72, unknown 22.5
Ventral tegmental area
nTPM: 28.4
2410 Female, age 72, unknown 34.7
2218 Male, age 76, both hemispheres 31.8
1915 Female, age 42, unknown 30.6
1942 Male, age 51, unknown 30.5
2021 Male, age 53, unknown 22.8
2223 Female, age 72, unknown 20.1

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 20.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 20.9
Samples: 183

Max nTPM: 47.8
Min nTPM: 3.9
Std nTPM: 9.8
Median nTPM: 19.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 47.8
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 44.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 42.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 41.5
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 41.3
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 41.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 40.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 39.7
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 39.1
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 38.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 38.1
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 1.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1.7
FF:10158-103A5 76 years, female 1.7

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 48.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 33.4
Samples: 4

Max nTPM: 48.1
Min nTPM: 20.8
Sample A Female 48.1
Sample B Female 30.9
Sample C Male 33.8
Sample D Male 20.8
Midbrain
nTPM: 37.9
Samples: 4

Max nTPM: 58.8
Min nTPM: 25.9
Sample A Female 30.2
Sample B Female 25.9
Sample C Male 58.8
Sample D Male 36.7
Periaqueductal gray
nTPM: 25.7
Samples: 3

Max nTPM: 29.2
Min nTPM: 21.6
Sample B Female 26.4
Sample C Male 29.2
Sample D Male 21.6
Superior colliculi
nTPM: 48.1
Samples: 4

Max nTPM: 55.3
Min nTPM: 35.3
Sample A Female 54.9
Sample B Female 46.8
Sample C Male 55.3
Sample D Male 35.3

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 51.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 51.5
Samples: 4

Max nTPM: 55.5
Min nTPM: 47.2
Sample A Male 55.5
Sample B Male 47.2
Sample C Female 48.9
Sample D Female 54.5

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 2.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.9
69527818 Antisense, RP_050421_02_E06, Mouse strain C57BL/6J (56 days, male) 3.3
73635786 Antisense, RP_051017_04_D12, Mouse strain C57BL/6J (56 days, male) 2.5

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