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BETA
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  • EEF2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:571.6 nTPM
HPA Brain:728.5 nTPM
GTEx:571.6 nTPM
FANTOM5:647.6 Scaled Tags Per Million
Macaque:327.9 nTPM
Mouse:873.6 nTPM
Rat:494.5 nTPM
Pig:632.9 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 140
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 250
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

728.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 658.6
2586 Male, age 75, left hemisphere 852.7
2828 Female, age 72, unknown 706.4
2666 Male, age 74, left hemisphere 706.2
1827 Male, age 72, unknown 644.6
2219 Male, age 76, both hemispheres 632.6
2411 Female, age 72, unknown 625.4
2019 Male, age 18, unknown 616.2
1870 Female, age 42, unknown 614.2
1833 Male, age 53, unknown 604.6
1830 Male, age 51, unknown 582.8
Dorsal raphe nucleus
nTPM: 610.6
2016 Female, age 72, unknown 622.6
2750 Male, age 76, both hemispheres 617.6
2298 Female, age 72, unknown 608.4
1828 Male, age 53, unknown 604.2
2047 Male, age 72, unknown 599.9
Inferior colliculus
nTPM: 617.8
1848 Female, age 42, unknown 667.3
2849 Male, age 72, unknown 611.0
1890 Male, age 53, unknown 607.9
2097 Female, age 72, unknown 585.1
Median raphe nucleus
nTPM: 566.9
2220 Male, age 76, midline 566.9
Periaquaductal grey, anterior
nTPM: 728.5
2502 Female, age 75, unknown 812.3
1947 Male, age 18, unknown 694.5
1795 Male, age 51, unknown 678.7
Periaquaductal grey, dorsal
nTPM: 544.6
1840 Male, age 53, unknown 617.5
2464 Female, age 72, unknown 574.4
1831 Male, age 72, unknown 535.1
2850 Male, age 76, both hemispheres 451.2
Periaquaductal grey, lateral
nTPM: 543.5
2272 Male, age 74, both hemispheres 588.8
2053 Male, age 18, unknown 586.4
2140 Male, age 76, both hemispheres 455.3
Pretectal area
nTPM: 602.6
1816 Male, age 51, unknown 683.2
2007 Male, age 72, unknown 669.6
1817 Female, age 42, unknown 667.3
1944 Female, age 72, unknown 623.8
1815 Male, age 53, unknown 608.7
2407 Male, age 75, both hemispheres 594.6
2825 Male, age 18, unknown 594.5
2667 Female, age 75, unknown 589.8
2224 Female, age 72, unknown 545.6
2273 Male, age 74, both hemispheres 536.7
2316 Male, age 76, right hemisphere 514.7
Red nucleus
nTPM: 647.7
2584 Male, age 75, left hemisphere 753.6
2503 Female, age 72, unknown 719.0
2588 Male, age 74, left hemisphere 665.6
2769 Male, age 72, unknown 664.7
2227 Male, age 72, unknown 661.3
1821 Female, age 72, unknown 655.7
1865 Male, age 51, unknown 653.5
2785 Male, age 18, unknown 638.0
1904 Male, age 53, unknown 637.0
1954 Female, age 42, unknown 608.7
2725 Female, age 75, unknown 567.4
2823 Male, age 76, right hemisphere 548.1
Substantia nigra
nTPM: 703.9
1916 Female, age 42, unknown 878.6
2665 Male, age 74, both hemispheres 785.4
1851 Male, age 51, unknown 773.7
2590 Female, age 75, unknown 696.6
2241 Male, age 72, unknown 691.7
1941 Male, age 53, unknown 685.3
2583 Male, age 75, right hemisphere 678.3
2699 Male, age 18, unknown 672.5
1889 Female, age 72, unknown 629.7
2409 Female, age 72, unknown 547.5
Superior colliculus
nTPM: 649.5
2664 Male, age 75, both hemispheres 770.5
1796 Male, age 53, unknown 702.3
2261 Male, age 18, unknown 701.6
2668 Female, age 75, unknown 671.1
2087 Female, age 72, unknown 649.4
2587 Male, age 74, left hemisphere 645.4
1839 Male, age 51, unknown 619.0
1913 Female, age 42, unknown 601.2
1995 Male, age 72, unknown 585.7
1895 Male, age 76, right hemisphere 548.9
Ventral tegmental area
nTPM: 663.0
2410 Female, age 72, unknown 713.3
1915 Female, age 42, unknown 689.4
2223 Female, age 72, unknown 662.8
2218 Male, age 76, both hemispheres 657.0
1942 Male, age 51, unknown 651.4
2021 Male, age 53, unknown 604.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

571.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 571.6
Samples: 183

Max nTPM: 1101.1
Min nTPM: 267.7
Std nTPM: 128.7
Median nTPM: 561.3
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 1101.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1014.5
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 945.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 920.2
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 879.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 868.2
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 833.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 828.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 819.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 804.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 796.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 779.6
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 772.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 747.3
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 746.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 736.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 736.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 735.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 732.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 715.8
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 713.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 699.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 699.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 693.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 684.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 683.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 681.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 680.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 679.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 678.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 674.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 673.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 667.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 667.2
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 666.3
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 663.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 661.1
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 653.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 651.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 648.0
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 643.5
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 643.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 641.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 639.2
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 638.1
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 634.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 632.5
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 630.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 628.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 627.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 627.1
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 624.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 622.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 619.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 618.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 617.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 614.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 611.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 609.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 607.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 606.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 605.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 605.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 602.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 601.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 597.9
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 596.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 596.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 594.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 593.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 591.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 588.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 587.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 587.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 587.1
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 584.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 584.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 583.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 583.5
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 583.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 580.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 578.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 576.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 575.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 574.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 571.6
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 568.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 567.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 567.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 565.6
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 562.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 561.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 560.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 558.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 557.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 557.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 556.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 556.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 555.8
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 555.4
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 555.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 554.4
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 554.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 549.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 549.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 546.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 540.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 540.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 538.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 537.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 535.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 535.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 534.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 532.5
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 531.2
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 530.6
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 529.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 527.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 525.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 522.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 521.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 518.9
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 518.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 517.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 513.1
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 510.8
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 510.8
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 510.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 509.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 508.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 506.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 506.3
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 502.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 501.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 498.4
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 497.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 496.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 489.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 485.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 485.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 481.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 479.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 479.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 479.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 474.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 472.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 472.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 470.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 466.5
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 455.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 454.3
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 451.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 450.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 449.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 446.9
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 442.3
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 441.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 440.9
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 438.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 437.5
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 437.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 434.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 427.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 418.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 417.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 415.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 415.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 409.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 408.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 406.5
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 401.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 400.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 398.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 392.6
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 389.9
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 386.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 361.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 353.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 350.6
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 332.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 311.9
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 268.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 267.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

647.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 647.6
FF:10158-103A5 76 years, female 647.6

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

327.9
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 294.1
Samples: 1

Max nTPM: 294.1
Min nTPM: 294.1
Sample A 294.1
Midbrain
nTPM: 232.3
Samples: 1

Max nTPM: 232.3
Min nTPM: 232.3
Sample A 232.3
Superior colliculi
nTPM: 327.9
Samples: 1

Max nTPM: 327.9
Min nTPM: 327.9
Sample A 327.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

632.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 543.9
Samples: 3

Max nTPM: 606.8
Min nTPM: 490.7
Sample A Female 606.8
Sample B Female 490.7
Sample C Male 534.3
Midbrain
nTPM: 546.8
Samples: 3

Max nTPM: 625.5
Min nTPM: 493.2
Sample B Female 493.2
Sample C Male 625.5
Sample D Male 521.7
Periaqueductal gray
nTPM: 414.3
Samples: 3

Max nTPM: 447.2
Min nTPM: 348.9
Sample B Female 446.9
Sample C Male 447.2
Sample D Male 348.9
Superior colliculi
nTPM: 632.9
Samples: 4

Max nTPM: 665.7
Min nTPM: 590.6
Sample A Female 665.7
Sample B Female 662.3
Sample C Male 613.0
Sample D Male 590.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

873.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 873.6
Samples: 4

Max nTPM: 930.0
Min nTPM: 825.9
Sample A 883.5
Sample B 930.0
Sample C 854.9
Sample D 825.9

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

494.5
Rat sample Sample description nTPM
Midbrain
nTPM: 494.5
Samples: 4

Max nTPM: 518.0
Min nTPM: 466.6
Sample A 518.0
Sample A 493.7
Sample A 499.6
Sample A 466.6

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