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BETA
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EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

69.287
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:1174.6 nTPM
FANTOM5:1131.8 Scaled Tags Per Million
Macaque:475.0 nTPM
Mouse:251.7 nTPM
Rat:813.2 nTPM
Pig:472.9 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity.

, antibody HPA023338
Pons mean intensity 69.287
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 24.826
Parabrachial nucleus 63.553
Principle sensory trigeminal nucleus 29.581
Locus coeruleus 69.287
Pontine nucleus 47.027
Vestibular nucleus 31.923
Pontine reticular nucleus, oral 48.078
Lateral lemniscus 12.826
Superior paraolivary nucleus 12.643

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1174.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 1104.5
2188 Female, age 91, both hemispheres 1286.8
2090 Male, age 80, both hemispheres 1268.8
2301 Female, age 85, both hemispheres 1259.6
1984 Male, age 76, both hemispheres 602.7
Dorsal cochlear nucleus
nTPM: 968.1
2378 Male, age 80, both hemispheres 1075.1
2187 Female, age 91, both hemispheres 1002.9
2802 Male, age 74, right hemisphere 999.4
2058 Male, age 76, both hemispheres 898.4
2370 Male, age 61, both hemispheres 864.8
Dorsal tegmental nucleus
nTPM: 807.0
2083 Male, age 80, both hemispheres 1182.7
2326 Male, age 74, both hemispheres 866.4
1936 Male, age 76, left hemisphere 650.6
2358 Male, age 61, both hemispheres 528.4
Dorsolateral tegmental area
nTPM: 860.5
2751 Female, age 85, both hemispheres 1277.4
2654 Male, age 80, both hemispheres 1085.2
2337 Male, age 61, both hemispheres 847.4
2360 Male, age 74, both hemispheres 607.9
2141 Male, age 76, both hemispheres 484.7
Kolliker-Fuse nucleus
nTPM: 905.0
2793 Female, age 91, left hemisphere 1198.0
2163 Male, age 80, both hemispheres 846.0
2315 Male, age 76, right hemisphere 671.0
Lateral lemniscal nuclei
nTPM: 868.7
2320 Female, age 91, left hemisphere 1088.2
2746 Female, age 85, left hemisphere 929.5
2169 Male, age 76, both hemispheres 833.0
2036 Male, age 80, both hemispheres 796.8
2453 Male, age 74, right hemisphere 695.7
Lateral parabrachial nucleus
nTPM: 1096.6
2792 Male, age 76, both hemispheres 1555.5
2013 Male, age 80, both hemispheres 1131.5
2790 Male, age 61, both hemispheres 949.8
2139 Female, age 85, right hemisphere 749.8
Lateral vestibular nucleus
nTPM: 908.7
2311 Male, age 80, both hemispheres 1014.6
2184 Male, age 76, both hemispheres 802.8
Locus coeruleus
nTPM: 497.1
2162 Male, age 80, both hemispheres 636.9
2317 Female, age 72, unknown 575.5
2720 Male, age 74, both hemispheres 525.5
2123 Female, age 91, both hemispheres 464.0
2014 Male, age 55, unknown 450.1
2788 Male, age 74, unknown 442.9
1980 Male, age 76, both hemispheres 384.4
Medial parabrachial nucleus
nTPM: 956.0
2463 Female, age 85, right hemisphere 1184.4
2170 Female, age 91, both hemispheres 1091.1
2786 Male, age 76, both hemispheres 888.0
2854 Male, age 80, both hemispheres 850.2
2156 Male, age 61, both hemispheres 766.4
Medial periolivary nuclei
nTPM: 885.1
2081 Male, age 80, both hemispheres 1132.1
2791 Male, age 74, right hemisphere 938.7
2063 Male, age 76, both hemispheres 926.5
2458 Female, age 91, both hemispheres 924.9
2171 Female, age 85, both hemispheres 503.2
Motor facial nucleus
nTPM: 938.7
2126 Male, age 61, both hemispheres 1344.9
2697 Female, age 85, both hemispheres 1023.4
2365 Male, age 74, right hemisphere 958.3
2062 Male, age 76, both hemispheres 811.9
2795 Female, age 91, both hemispheres 788.7
2327 Male, age 80, both hemispheres 705.1
Motor trigeminal nucleus
nTPM: 890.4
2321 Female, age 91, both hemispheres 978.7
2560 Male, age 74, both hemispheres 931.1
2309 Male, age 76, both hemispheres 910.1
2079 Male, age 80, both hemispheres 853.0
2335 Male, age 61, both hemispheres 779.2
Nuclei of the trapezoid body
nTPM: 807.6
2166 Male, age 80, both hemispheres 1030.3
2368 Female, age 91, both hemispheres 919.8
1983 Male, age 76, both hemispheres 845.5
2159 Male, age 61, both hemispheres 759.7
2735 Female, age 85, both hemispheres 482.7
Nucleus raphe magnus
nTPM: 725.1
2459 Female, age 91, both hemispheres 1006.4
2051 Male, age 76, both hemispheres 957.8
2328 Male, age 80, both hemispheres 912.4
2455 Male, age 74, both hemispheres 707.6
2160 Male, age 61, both hemispheres 425.8
2172 Female, age 85, both hemispheres 340.6
Paramedian reticular nucleus
nTPM: 887.6
2057 Male, age 80, both hemispheres 1110.7
2052 Male, age 76, both hemispheres 886.5
2050 Female, age 85, both hemispheres 780.7
2313 Male, age 61, both hemispheres 772.4
Pedunculopontine tegmental nucleus
nTPM: 773.6
2334 Male, age 80, both hemispheres 867.8
1921 Female, age 85, both hemispheres 732.7
2338 Male, age 61, both hemispheres 720.2
Pontine nuclei
nTPM: 992.2
2454 Male, age 74, left hemisphere 1332.6
2319 Female, age 91, both hemispheres 1229.9
2109 Female, age 72, unknown 1184.3
1968 Male, age 76, left hemisphere 1047.5
2115 Male, age 80, left hemisphere 999.4
1863 Male, age 55, unknown 960.6
2727 Male, age 61, right hemisphere 645.5
2787 Female, age 85, both hemispheres 537.6
Pontine raphe nucleus
nTPM: 659.3
2853 Male, age 76, midline 680.9
2122 Female, age 85, midline 637.7
Posteroventral cochlear nucleus
nTPM: 1174.6
2135 Female, age 91, both hemispheres 1546.3
2341 Male, age 80, both hemispheres 1315.6
2070 Male, age 76, both hemispheres 1229.2
2371 Male, age 61, both hemispheres 1016.8
2752 Female, age 85, both hemispheres 765.3
Principal sensory trigeminal nucleus
nTPM: 776.1
2367 Female, age 91, left hemisphere 1106.3
2324 Male, age 76, both hemispheres 731.5
2008 Male, age 80, left hemisphere 698.5
2158 Male, age 61, both hemispheres 568.2
Reticular pontine nucleus, caudal
nTPM: 1070.3
2559 Male, age 74, both hemispheres 1230.3
2457 Female, age 91, both hemispheres 1198.6
2092 Male, age 76, both hemispheres 1142.7
2332 Male, age 80, right hemisphere 709.8
Reticular pontine nucleus, oral
nTPM: 1071.0
2366 Female, age 91, both hemispheres 1278.0
2361 Male, age 74, both hemispheres 1119.1
1939 Male, age 80, both hemispheres 1069.0
2167 Male, age 76, both hemispheres 984.0
2012 Female, age 85, both hemispheres 905.0
Reticulotegmental nucleus
nTPM: 779.8
2322 Female, age 91, both hemispheres 893.0
2333 Male, age 80, both hemispheres 867.4
2452 Male, age 74, both hemispheres 863.4
2325 Male, age 76, both hemispheres 495.5
Spinal trigeminal nucleus, oral
nTPM: 842.6
1978 Male, age 76, both hemispheres 966.1
2164 Male, age 80, both hemispheres 905.8
2737 Female, age 85, both hemispheres 655.8
Subcoeruleus area
nTPM: 913.5
2369 Female, age 85, left hemisphere 1471.1
2089 Male, age 76, left hemisphere 931.6
1958 Male, age 80, both hemispheres 784.2
2451 Male, age 74, both hemispheres 743.5
2323 Female, age 91, left hemisphere 637.0
Superior olive
nTPM: 977.8
2020 Male, age 76, both hemispheres 1293.3
2364 Male, age 74, right hemisphere 1001.0
2329 Male, age 80, right hemisphere 940.6
2561 Female, age 91, both hemispheres 882.5
1875 Female, age 85, both hemispheres 771.7
Ventral periolivary nuclei
nTPM: 819.2
2023 Male, age 76, both hemispheres 1270.2
2165 Male, age 80, both hemispheres 786.4
2794 Female, age 91, left hemisphere 659.0
2130 Female, age 85, both hemispheres 561.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 941.5
2456 Female, age 91, both hemispheres 1118.5
2359 Male, age 61, both hemispheres 1065.1
1959 Male, age 76, both hemispheres 973.1
2161 Male, age 80, both hemispheres 902.4
2840 Female, age 85, both hemispheres 822.0
2449 Male, age 74, both hemispheres 767.9

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1131.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 835.2
FF:10182-103D2 60 years, female 954.7
FF:10165-103B3 76 years, female 715.7
Pons
Scaled Tags Per Million: 1131.8
FF:10033-101E6 18-54 years, mixed 1131.8

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

475.0
Macaque sample Sample description nTPM
Pons
nTPM: 475.1
Samples: 2

Max nTPM: 520.6
Min nTPM: 429.5
Sample A 520.6
Sample B 429.5

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

472.9
Pig sample Sample description nTPM
Pons
nTPM: 472.9
Samples: 3

Max nTPM: 567.0
Min nTPM: 402.9
Sample A Female 448.7
Sample B Female 402.9
Sample C Male 567.0

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

251.7
Mouse sample Sample description nTPM
Pons
nTPM: 251.7
Samples: 4

Max nTPM: 264.5
Min nTPM: 238.5
Sample A 264.5
Sample B 238.5
Sample C 257.9
Sample D 245.9

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

813.2
Rat sample Sample description nTPM
Pons
nTPM: 813.2
Samples: 4

Max nTPM: 924.7
Min nTPM: 710.7
Sample A 730.3
Sample A 710.7
Sample A 924.7
Sample A 887.1

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