BETA
CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Medium
Glial cells: Medium
Neuronal cells: High
Neuropil: Low
RNA expressioni
Consensus:152.7 nTPM
HPA:50.6 nTPM
HPA Brain:122.3 nTPM
HPA PFC Brain:92.6 nTPM
GTEx:152.7 nTPM
CEREBRAL CORTEX - SINGLE NUCLEI RNA EXPRESSIONi

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NEURONSi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 20
c-1 Excitatory (VGLUT1) CUX2+
c-2 Inhibitory (GAD1/2) LHX6+ T...
c-3 Inhibitory (GAD1/2) CXCL14+...
c-4 Inhibitory (GAD1/2) LHX6+ T...
c-5 Inhibitory (GAD1/2) CXCL14+
c-6 Excitatory (VGLUT1) FOXP2+
c-7 Excitatory (VGLUT1) CUX2+
c-8 Excitatory (VGLUT1)
c-9 Inhibitory (GAD1/2) LHX6+ T...
c-10 Inhibitory (GAD1/2) CXCL14+...
c-11 Inhibitory (GAD1/2) CXCL14+...
c-12 Excitatory (VGLUT1) FOXP2+
c-13 Excitatory (VGLUT1) FOXP2+
c-14 Excitatory (VGLUT1) CUX2+
c-15 Excitatory (VGLUT1) FOXP2+
c-16 Inhibitory (GAD1/2) CXCL14+...
c-17 Excitatory (VGLUT1/2)
c-18 Excitatory (VGLUT1) FOXP2+
c-19 Excitatory (VGLUT1/2) CUX2+
c-20 Inhibitory (GAD1/2) LAMP5+ ...
c-21 Excitatory (VGLUT1) FOXP2+
c-22 Inhibitory (GAD1/2) CXCL14+
c-23 Excitatory (VGLUT1) FOXP2+
c-24 Excitatory (VGLUT1) SOX5+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NON-NEURONALi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 30
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Oligodendrocyte progenitor ...
c-4 Oligodendrocytes
c-5 Astrocytes
c-6 Astrocytes
c-7 Microglia
c-8 Oligodendrocyte progenitor ...
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Astrocytes
c-12 Astrocytes
c-13 Astrocytes
c-14 Microglia
c-15 Vascular endothelial cells
c-16 Fibroblasts
c-17 Oligodendrocytes (CNTN1+)
c-18 Macrophages
c-19 Immature oligodendrocytes
c-20 Oligodendrocyte progenitor ...
c-21 Pericytes
c-22 Lymphocytes
c-23 Fibroblasts
c-24 Vascular smooth muscle cell
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA046697Antibody HPA061174
Endothelial cells MediumLow
Glial cells MediumLow
Neuronal cells HighHigh
Neuropil LowNot detected





CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity 5326
Sample Intensity
Cerebral cortex_01
 6298
Cerebral cortex_02
 5101
Cerebral cortex_03
 8616
Cerebral cortex_04
 5984
Cerebral cortex_05
 3682
Cerebral cortex_06
 6538
Cerebral cortex_07
 5921
Cerebral cortex_08
 5551
Cerebral cortex_09
 3392
Cerebral cortex_10
 5853
Cerebral cortex_11
 4039
Cerebral cortex_12
 6651
Cerebral cortex_13
 6021
Cerebral cortex_14
 4572
Cerebral cortex_15
 7569
Cerebral cortex_16
 4358
Cerebral cortex_17
 4249
Cerebral cortex_18
 6126
Cerebral cortex_19
 6756
Cerebral cortex_20
 6854
Cerebral cortex_21
 4093
Cerebral cortex_22
 5022
Cerebral cortex_23
 4281
Cerebral cortex_24
 7791
Cerebral cortex_25
 6388
Cerebral cortex_26
 7430
Cerebral cortex_27
 6125
Cerebral cortex_28
 3562
Cerebral cortex_29
 2742
Cerebral cortex_30
 5660
Cerebral cortex_31
 4425
Cerebral cortex_32
 2940
Cerebral cortex_33
 5554
Cerebral cortex_34
 4086
Cerebral cortex_35
 4215
Cerebral cortex_36
 4675
Cerebral cortex_37
 4270
Cerebral cortex_38
 4520

CEREBRAL CORTEX - MANN MS
Median intensity ND
Replicate Intensity
Cerebral cortex_01
 ND
Cerebral cortex_02
 ND
Cerebral cortex_03
 ND

CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 50.6
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 59.1
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 33.1
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 59.4
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain Stereo-seq

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 122.3
Sample id Sample description nTPM
Angular gyrus
nTPM: 87.6
2221 Female, age 67, right hemisphere 117.5
1866 Male, age 76, both hemispheres 98.0
2602 Female, age 94, right hemisphere 97.2
2260 Female, age 72, left hemisphere 96.6
1790 Male, age 76, right hemisphere 84.7
2103 Male, age 75, left hemisphere 80.4
2722 Male, age 61, left hemisphere 74.0
2265 Female, age 91, left hemisphere 52.6
Angular gyrus (white matter)
nTPM: 55.0
1920 Male, age 76, both hemispheres 55.0
Anterior cingulate cortex, supragenual-dorsal
nTPM: 78.1
2547 Male, age 74, left hemisphere 95.3
1896 Female, age 85, right hemisphere 82.0
2472 Male, age 75, left hemisphere 79.0
2342 Female, age 94, right hemisphere 70.8
2478 Female, age 67, right hemisphere 63.6
Anterior cingulate cortex, supragenual-ventral
nTPM: 73.4
1761 Male, age 74, left hemisphere 84.2
2538 Male, age 75, left hemisphere 82.0
1950 Female, age 85, right hemisphere 77.7
1755 Female, age 94, right hemisphere 75.7
2479 Female, age 67, right hemisphere 47.5
Anterior insular cortex, dorsal
nTPM: 75.3
2506 Female, age 94, right hemisphere 92.7
2001 Male, age 76, right hemisphere 86.4
2670 Male, age 75, left hemisphere 66.8
2235 Female, age 91, right hemisphere 55.3
Anterior insular cortex, ventral
nTPM: 86.6
1925 Female, age 91, left hemisphere 113.3
1852 Male, age 76, left hemisphere 99.0
2262 Female, age 67, right hemisphere 81.8
2507 Female, age 94, left hemisphere 81.0
2757 Male, age 61, right hemisphere 79.1
2596 Male, age 75, left hemisphere 65.6
Area parastriata, inferior
nTPM: 71.4
1758 Female, age 72, right hemisphere 91.4
1789 Male, age 76, right hemisphere 87.2
1760 Female, age 67, left hemisphere 79.2
2268 Male, age 61, right hemisphere 78.9
2234 Male, age 75, left hemisphere 75.0
2421 Female, age 91, left hemisphere 45.2
2509 Female, age 94, left hemisphere 43.1
Area parastriata, parietal
nTPM: 73.1
1785 Male, age 76, right hemisphere 82.6
2680 Female, age 94, right hemisphere 76.6
2420 Male, age 75, left hemisphere 69.7
2236 Female, age 91, left hemisphere 68.5
2233 Male, age 61, right hemisphere 68.1
Area parastriata, superior
nTPM: 72.9
1773 Female, age 91, left hemisphere 112.4
2881 Male, age 76, left hemisphere 91.6
2419 Male, age 75, right hemisphere 69.5
2604 Female, age 94, right hemisphere 63.3
2684 Female, age 67, left hemisphere 60.3
2435 Male, age 61, left hemisphere 40.0
Area parastriata, temporal
nTPM: 79.1
1804 Male, age 76, right hemisphere 94.5
2471 Male, age 75, left hemisphere 85.5
2681 Female, age 94, right hemisphere 75.4
2424 Female, age 67, left hemisphere 71.1
2267 Male, age 61, right hemisphere 68.9
Area striata
nTPM: 66.0
1753 Female, age 72, right hemisphere 83.5
2679 Female, age 94, right hemisphere 74.0
2417 Male, age 61, right hemisphere 69.0
2427 Female, age 91, left hemisphere 68.6
2002 Female, age 91, right hemisphere 58.0
1884 Male, age 76, left hemisphere 42.7
Area striata (white matter)
nTPM: 57.3
2258 Female, age 91, left hemisphere 57.3
Claustrum
nTPM: 83.5
2198 Male, age 80, both hemispheres 103.4
2568 Male, age 61, both hemispheres 94.7
2196 Female, age 79, unknown 93.4
2645 Female, age 72, unknown 90.1
2284 Female, age 91, both hemispheres 86.5
1956 Male, age 74, unknown 84.4
2491 Male, age 75, both hemispheres 72.6
2392 Female, age 94, both hemispheres 67.5
2292 Female, age 85, both hemispheres 58.6
Corpus callosum, genu (white matter)
nTPM: 40.6
2771 Male, age 75, left hemisphere 63.2
1886 Female, age 67, right hemisphere 59.9
1849 Female, age 91, right hemisphere 35.6
1885 Female, age 94, left hemisphere 34.8
1934 Male, age 61, right hemisphere 32.1
1887 Male, age 76, left hemisphere 18.2
Corpus callosum, splenium (white matter)
nTPM: 46.6
2104 Male, age 75, left hemisphere 72.0
2847 Female, age 67, right hemisphere 66.6
2238 Female, age 94, right hemisphere 29.3
1946 Male, age 76, left hemisphere 18.4
Frontal eye field
nTPM: 89.0
2761 Female, age 94, left hemisphere 99.8
2543 Male, age 74, left hemisphere 99.6
2441 Male, age 75, left hemisphere 81.4
2147 Male, age 61, left hemisphere 75.2
Frontal operculum
nTPM: 69.8
2348 Male, age 75, left hemisphere 71.5
2030 Male, age 61, right hemisphere 71.4
2781 Female, age 85, right hemisphere 66.5
Fusiform gyrus
nTPM: 95.4
2784 Female, age 85, left hemisphere 113.9
1807 Male, age 76, left hemisphere 108.5
2617 Female, age 94, left hemisphere 106.0
2112 Male, age 80, both hemispheres 100.0
2433 Female, age 72, left hemisphere 93.8
2074 Female, age 91, left hemisphere 79.8
2431 Male, age 75, right hemisphere 65.9
Inferior frontal gyrus, opercular
nTPM: 97.0
2873 Female, age 85, left hemisphere 120.2
2866 Male, age 61, right hemisphere 111.7
2865 Male, age 61, left hemisphere 111.5
2872 Female, age 94, right hemisphere 100.4
2871 Female, age 94, left hemisphere 97.0
2874 Female, age 85, right hemisphere 88.2
2868 Male, age 75, right hemisphere 87.6
2869 Male, age 74, left hemisphere 86.4
2875 Female, age 67, left hemisphere 84.4
2867 Male, age 75, left hemisphere 82.7
Inferior parietal lobule
nTPM: 83.1
2876 Male, age 76, right hemisphere 101.5
2418 Male, age 75, left hemisphere 83.0
2599 Female, age 94, left hemisphere 79.6
2606 Female, age 67, right hemisphere 68.2
Inferior temporal gyrus
nTPM: 87.2
1880 Male, age 80, right hemisphere 119.2
1808 Male, age 76, left hemisphere 95.0
1965 Female, age 91, left hemisphere 93.9
2689 Female, age 94, right hemisphere 74.7
1970 Female, age 85, right hemisphere 71.8
2430 Male, age 75, right hemisphere 68.7
Intraparietal deep sulcus
nTPM: 67.3
2798 Male, age 76, left hemisphere 92.9
2230 Male, age 61, right hemisphere 80.5
2607 Female, age 67, right hemisphere 61.2
2600 Female, age 94, right hemisphere 60.1
2669 Male, age 75, left hemisphere 59.2
2102 Female, age 91, left hemisphere 49.7
Lingual gyrus
nTPM: 91.5
2838 Male, age 80, right hemisphere 114.4
1893 Male, age 76, left hemisphere 99.7
2618 Female, age 94, left hemisphere 94.1
2688 Male, age 75, right hemisphere 81.0
2073 Female, age 85, left hemisphere 68.2
Middle cingulate cortex
nTPM: 74.8
2357 Female, age 67, right hemisphere 93.8
2640 Female, age 94, right hemisphere 79.1
2028 Female, age 85, left hemisphere 77.6
2539 Male, age 75, left hemisphere 63.7
2633 Male, age 74, left hemisphere 59.9
Middle temporal gyrus
nTPM: 97.6
1819 Male, age 80, right hemisphere 118.3
1799 Male, age 76, left hemisphere 99.3
2616 Female, age 94, left hemisphere 95.9
2034 Female, age 91, right hemisphere 94.7
2611 Male, age 75, right hemisphere 79.7
Occipital cortex
nTPM: 85.0
2608 Female, age 67, both hemispheres 101.6
1842 Male, age 76, right hemisphere 90.5
2426 Male, age 75, midline 87.4
2677 Female, age 67, right hemisphere 72.7
2470 Male, age 75, right hemisphere 72.6
Occipital cortex (white matter)
nTPM: 68.8
2259 Male, age 75, midline 72.2
2257 Female, age 67, both hemispheres 65.5
Olfactory area
nTPM: 96.9
2222 Female, age 67, right hemisphere 127.1
2756 Female, age 67, right hemisphere 126.5
1805 Female, age 85, right hemisphere 94.8
2352 Female, age 94, right hemisphere 92.9
2440 Male, age 75, left hemisphere 72.7
2542 Male, age 74, left hemisphere 67.2
Olfactory tubercle
nTPM: 100.0
1846 Male, age 80, right hemisphere 115.5
1998 Female, age 91, both hemispheres 114.3
2487 Female, age 94, left hemisphere 97.4
2856 Male, age 75, right hemisphere 72.8
Orbitofrontal gyrus, anterior
nTPM: 122.3
2863 Female, age 85, right hemisphere 268.4
2864 Female, age 67, left hemisphere 53.4
2862 Female, age 85, left hemisphere 45.0
Paracentral lobule, anterior
nTPM: 103.2
2340 Female, age 67, right hemisphere 111.3
2474 Male, age 74, left hemisphere 105.5
1776 Female, age 85, right hemisphere 102.9
1754 Male, age 75, left hemisphere 100.7
1926 Male, age 61, left hemisphere 99.7
2638 Female, age 94, right hemisphere 98.8
Paracentral lobule, posterior
nTPM: 79.8
1775 Female, age 85, right hemisphere 97.7
1764 Male, age 74, right hemisphere 93.4
2345 Male, age 61, left hemisphere 81.5
2551 Female, age 94, right hemisphere 64.4
2446 Male, age 75, left hemisphere 62.2
Parahippocampal cortex (white matter)
nTPM: 63.7
2157 Female, age 91, both hemispheres 63.7
Parietal operculum
nTPM: 86.8
2552 Female, age 94, right hemisphere 92.8
2356 Female, age 67, right hemisphere 89.8
1763 Male, age 74, left hemisphere 82.3
2719 Male, age 75, left hemisphere 82.3
Parieto-insular cortex
nTPM: 85.9
1976 Female, age 91, right hemisphere 139.5
2831 Male, age 76, right hemisphere 94.3
2232 Male, age 61, right hemisphere 75.7
2508 Female, age 94, right hemisphere 59.9
2671 Male, age 75, left hemisphere 59.9
Parieto-occipital transitional area
nTPM: 72.9
1784 Male, age 76, right hemisphere 88.1
2674 Female, age 94, right hemisphere 79.1
2270 Male, age 61, right hemisphere 79.0
2468 Male, age 75, left hemisphere 70.1
2683 Female, age 67, left hemisphere 48.3
Parieto-temporal junction (white matter)
nTPM: 37.8
2469 Male, age 75, right hemisphere 60.8
1999 Female, age 67, right hemisphere 47.6
1935 Female, age 94, right hemisphere 41.6
2770 Female, age 91, right hemisphere 29.8
2774 Male, age 61, right hemisphere 29.0
2121 Male, age 76, left hemisphere 17.8
Piriform cortex
nTPM: 57.0
2347 Male, age 75, right hemisphere 76.1
2153 Female, age 85, left hemisphere 37.8
Postcentral gyrus
nTPM: 107.7
2533 Male, age 75, right hemisphere 107.7
Postcentral gyrus, dorsal
nTPM: 88.4
2544 Male, age 74, left hemisphere 102.6
2339 Female, age 67, right hemisphere 102.0
1836 Female, age 85, right hemisphere 92.4
2151 Male, age 61, left hemisphere 82.1
2477 Female, age 94, right hemisphere 76.7
2350 Male, age 75, left hemisphere 74.4
Postcentral gyrus, middle
nTPM: 100.0
2545 Male, age 74, left hemisphere 162.9
2146 Female, age 67, right hemisphere 108.4
1897 Female, age 85, right hemisphere 80.3
2248 Male, age 61, left hemisphere 74.8
2444 Male, age 75, left hemisphere 73.4
Postcentral gyrus, ventral
nTPM: 79.4
2445 Male, age 75, left hemisphere 90.4
2836 Female, age 94, right hemisphere 80.9
2024 Female, age 85, right hemisphere 66.9
Posterior cingulate cortex
nTPM: 81.6
2553 Female, age 94, right hemisphere 84.1
2473 Male, age 75, left hemisphere 83.1
1759 Male, age 74, right hemisphere 77.6
Posterior cingulate cortex, dorsal
nTPM: 68.4
2343 Male, age 61, left hemisphere 78.5
2641 Female, age 94, right hemisphere 75.3
2076 Female, age 85, right hemisphere 69.1
2540 Male, age 75, right hemisphere 67.8
2556 Female, age 67, right hemisphere 64.5
2634 Male, age 74, left hemisphere 55.2
Posterior cingulate cortex, ventral
nTPM: 71.0
2346 Male, age 61, left hemisphere 86.5
1762 Female, age 94, right hemisphere 81.3
2635 Male, age 74, left hemisphere 70.5
1994 Female, age 85, right hemisphere 67.3
2541 Male, age 75, right hemisphere 63.5
2448 Female, age 67, right hemisphere 57.1
Posterior insular cortex
nTPM: 91.6
2832 Female, age 91, right hemisphere 126.8
2603 Female, age 94, left hemisphere 107.3
1823 Male, age 76, right hemisphere 85.7
2511 Female, age 67, right hemisphere 78.8
2597 Male, age 75, left hemisphere 78.3
2231 Male, age 61, left hemisphere 72.6
Precentral gyrus
nTPM: 85.9
2557 Male, age 75, right hemisphere 85.9
Precentral gyrus, dorsal
nTPM: 78.9
1756 Male, age 74, left hemisphere 89.9
2354 Female, age 67, right hemisphere 88.0
2442 Male, age 75, left hemisphere 69.8
2476 Female, age 94, right hemisphere 68.0
Precentral gyrus, middle
nTPM: 94.4
1969 Female, age 67, right hemisphere 140.8
1909 Male, age 61, left hemisphere 101.4
2549 Female, age 94, right hemisphere 93.8
2443 Male, age 75, left hemisphere 72.8
2475 Male, age 74, right hemisphere 63.4
Precentral gyrus, ventral
nTPM: 93.8
2678 Male, age 74, left hemisphere 107.1
2662 Female, age 67, right hemisphere 103.6
2550 Female, age 94, right hemisphere 85.0
2630 Male, age 75, left hemisphere 79.4
Precuneus
nTPM: 80.4
1782 Male, age 76, right hemisphere 103.1
2594 Male, age 61, left hemisphere 90.7
1780 Female, age 91, right hemisphere 79.9
2673 Female, age 94, right hemisphere 76.8
2467 Male, age 75, right hemisphere 68.7
2510 Female, age 67, right hemisphere 63.3
Premotor cortex, dorsal
nTPM: 80.3
2027 Male, age 61, left hemisphere 97.5
1878 Female, age 85, right hemisphere 85.9
2631 Male, age 74, left hemisphere 79.7
2536 Male, age 75, left hemisphere 74.7
2554 Female, age 67, right hemisphere 63.6
Premotor cortex, ventral
nTPM: 93.3
1777 Female, age 67, left hemisphere 146.9
1779 Male, age 61, left hemisphere 108.2
2637 Female, age 94, right hemisphere 83.7
1881 Female, age 85, right hemisphere 77.8
1757 Male, age 74, left hemisphere 73.5
2349 Male, age 75, left hemisphere 69.6
Retrosplenial cortex
nTPM: 76.9
1951 Male, age 61, right hemisphere 97.0
2675 Female, age 94, left hemisphere 72.9
1914 Male, age 76, right hemisphere 60.8
Somatomor cortex, precentral gyrus (white matter)
nTPM: 81.3
2439 Male, age 75, right hemisphere 81.3
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 88.0
2623 Male, age 75, right hemisphere 88.0
Subcentral gyrus, S2
nTPM: 78.5
2762 Male, age 74, left hemisphere 93.8
2839 Female, age 94, right hemisphere 88.5
2072 Male, age 61, left hemisphere 88.3
2351 Male, age 75, left hemisphere 76.6
1964 Female, age 85, right hemisphere 65.7
2555 Female, age 67, right hemisphere 58.4
Superior parietal lobule
nTPM: 76.6
1800 Male, age 76, right hemisphere 91.3
1992 Female, age 91, right hemisphere 84.5
2229 Male, age 61, right hemisphere 73.6
2605 Female, age 67, right hemisphere 67.6
2672 Female, age 94, right hemisphere 65.9
Superior temporal gyrus
nTPM: 98.8
1844 Female, age 91, left hemisphere 126.3
2615 Female, age 94, left hemisphere 122.2
1843 Male, age 76, left hemisphere 97.6
2025 Male, age 80, right hemisphere 79.3
2687 Male, age 75, right hemisphere 68.4
Supplementary motor cortex
nTPM: 85.4
2548 Female, age 94, right hemisphere 95.1
2537 Male, age 75, left hemisphere 92.5
1993 Male, age 61, left hemisphere 87.9
2632 Male, age 74, left hemisphere 66.1
Supramarginal gyrus
nTPM: 83.6
1991 Female, age 91, right hemisphere 94.4
1798 Male, age 76, right hemisphere 85.6
2513 Female, age 72, left hemisphere 83.6
2415 Male, age 61, left hemisphere 78.9
2601 Female, age 94, left hemisphere 75.3
Temporal pole
nTPM: 105.4
1832 Female, age 91, left hemisphere 162.6
1853 Female, age 85, right hemisphere 109.5
2612 Female, age 94, left hemisphere 104.1
1826 Male, age 76, right hemisphere 86.3
2518 Male, age 75, right hemisphere 64.4
Temporal white matter
nTPM: 34.6
2254 Male, age 75, right hemisphere 60.2
2736 Female, age 91, right hemisphere 40.2
2523 Female, age 94, left hemisphere 30.6
2524 Female, age 85, left hemisphere 24.9
1801 Male, age 76, left hemisphere 17.2
Temporo-insular cortex, parainsular gyrus
nTPM: 67.8
1802 Male, age 76, left hemisphere 96.4
2598 Male, age 75, left hemisphere 79.3
2676 Female, age 94, right hemisphere 69.0
2416 Male, age 61, right hemisphere 60.5
2264 Female, age 91, right hemisphere 52.4
2512 Female, age 67, right hemisphere 49.3
Temporo-occipital transitional zone
nTPM: 76.5
1793 Male, age 80, right hemisphere 125.5
1900 Male, age 76, left hemisphere 55.8
2251 Female, age 85, right hemisphere 48.0
Transversal temporal gyrus, anterior
nTPM: 92.9
1888 Female, age 91, left hemisphere 130.5
2522 Female, age 94, left hemisphere 90.1
1910 Male, age 80, right hemisphere 86.4
1809 Male, age 76, right hemisphere 79.8
2610 Male, age 75, right hemisphere 77.6
Transversal temporal gyrus, posterior
nTPM: 84.7
2833 Male, age 80, right hemisphere 103.7
2614 Female, age 94, left hemisphere 87.0
1967 Female, age 91, right hemisphere 84.5
1922 Male, age 76, left hemisphere 80.9
2520 Male, age 75, right hemisphere 67.5

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 92.6
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 80.6
1516 Female, age 85, left hemisphere 145.0
1511 Male, age 61, right hemisphere 98.4
1510 Male, age 61, left hemisphere 96.3
1514 Male, age 74, right hemisphere 94.7
1513 Male, age 74, left hemisphere 71.9
1515 Female, age 94, right hemisphere 69.9
1518 Female, age 67, right hemisphere 53.7
1517 Female, age 67, left hemisphere 49.1
1512 Male, age 75, left hemisphere 46.3
Anterior cingulate gyrus, pregenual-ventral
nTPM: 87.6
1519 Male, age 61, left hemisphere 111.4
1521 Male, age 74, left hemisphere 108.6
1522 Male, age 74, right hemisphere 94.4
1523 Female, age 67, left hemisphere 71.0
1520 Male, age 75, right hemisphere 52.8
Anterior cingulate gyrus, subgenual
nTPM: 85.1
1529 Female, age 85, left hemisphere 175.0
1528 Male, age 74, right hemisphere 86.5
1527 Male, age 74, left hemisphere 86.4
1524 Male, age 61, left hemisphere 82.9
1530 Female, age 67, right hemisphere 59.8
1526 Male, age 75, right hemisphere 54.6
1525 Male, age 75, left hemisphere 50.7
Dorsolateral prefrontal cortex
nTPM: 75.7
1449 Female, age 85, right hemisphere 98.7
1446 Male, age 74, right hemisphere 83.7
1447 Female, age 94, left hemisphere 77.5
1448 Female, age 94, right hemisphere 72.7
1450 Female, age 67, right hemisphere 71.9
1445 Male, age 75, right hemisphere 62.8
1444 Male, age 75, left hemisphere 62.2
Dorsomedial prefrontal cortex
nTPM: 72.6
1439 Male, age 61, left hemisphere 90.3
1442 Male, age 75, right hemisphere 80.9
1440 Male, age 61, right hemisphere 77.7
1441 Male, age 75, left hemisphere 64.2
1443 Female, age 67, right hemisphere 49.6
Frontomarginal cortex
nTPM: 84.9
1471 Female, age 85, left hemisphere 157.0
1466 Male, age 61, right hemisphere 112.7
1468 Male, age 74, left hemisphere 90.3
1469 Female, age 94, left hemisphere 90.2
1465 Male, age 61, left hemisphere 85.9
1470 Female, age 94, right hemisphere 66.1
1467 Male, age 75, right hemisphere 64.6
1473 Female, age 67, right hemisphere 54.9
1472 Female, age 67, left hemisphere 42.8
Frontopolar cortex
nTPM: 69.2
1459 Male, age 61, right hemisphere 102.6
1458 Male, age 61, left hemisphere 83.3
1462 Female, age 94, left hemisphere 79.0
1461 Male, age 75, right hemisphere 71.9
1460 Male, age 75, left hemisphere 62.9
1463 Female, age 67, left hemisphere 47.6
1464 Female, age 67, right hemisphere 37.2
Gyrus rectus
nTPM: 69.2
1480 Female, age 85, left hemisphere 124.4
1475 Male, age 61, right hemisphere 87.7
1474 Male, age 61, left hemisphere 77.3
1478 Female, age 94, left hemisphere 72.5
1479 Female, age 94, right hemisphere 63.4
1476 Male, age 75, left hemisphere 52.9
1477 Male, age 75, right hemisphere 44.9
1481 Female, age 67, left hemisphere 30.1
Inferior frontal gyrus, orbital
nTPM: 82.6
1508 Female, age 85, right hemisphere 132.8
1500 Male, age 61, left hemisphere 101.1
1506 Female, age 94, left hemisphere 99.4
1504 Male, age 74, left hemisphere 97.0
1501 Male, age 61, right hemisphere 95.5
1505 Male, age 74, right hemisphere 80.2
1502 Male, age 75, left hemisphere 62.9
1503 Male, age 75, right hemisphere 57.7
1507 Female, age 85, left hemisphere 52.1
1509 Female, age 67, right hemisphere 46.9
Inferior frontal gyrus, triangular
nTPM: 90.2
1548 Female, age 85, right hemisphere 127.2
1545 Male, age 74, right hemisphere 117.3
1543 Male, age 61, right hemisphere 113.0
1546 Female, age 94, right hemisphere 94.4
1542 Male, age 61, left hemisphere 87.3
1547 Female, age 85, left hemisphere 66.7
1549 Female, age 67, left hemisphere 58.6
1544 Male, age 75, right hemisphere 57.1
Orbitofrontal gyrus, lateral
nTPM: 85.4
1498 Female, age 85, right hemisphere 138.6
1493 Male, age 61, right hemisphere 98.0
1497 Female, age 85, left hemisphere 90.0
1496 Female, age 94, right hemisphere 80.2
1495 Female, age 94, left hemisphere 78.2
1494 Male, age 75, left hemisphere 60.2
1499 Female, age 67, right hemisphere 52.3
Orbitofrontal gyrus, medial
nTPM: 61.3
1490 Female, age 85, right hemisphere 119.8
1489 Female, age 85, left hemisphere 93.8
1485 Male, age 74, left hemisphere 68.0
1488 Female, age 94, right hemisphere 65.7
1482 Male, age 61, left hemisphere 65.4
1487 Female, age 94, left hemisphere 52.3
1491 Female, age 67, left hemisphere 46.6
1486 Male, age 74, right hemisphere 45.8
1483 Male, age 75, left hemisphere 41.8
1492 Female, age 67, right hemisphere 38.3
1484 Male, age 75, right hemisphere 36.4
Orbitofrontal gyrus, posterior
nTPM: 85.0
1538 Female, age 85, left hemisphere 132.0
1539 Female, age 85, right hemisphere 113.0
1536 Female, age 94, left hemisphere 99.9
1532 Male, age 61, right hemisphere 97.6
1531 Male, age 61, left hemisphere 90.2
1537 Female, age 94, right hemisphere 89.0
1533 Male, age 75, left hemisphere 79.5
1535 Male, age 74, left hemisphere 76.8
1534 Male, age 75, right hemisphere 55.0
1541 Female, age 67, right hemisphere 51.6
1540 Female, age 67, left hemisphere 51.0
Subcallosal gyrus
nTPM: 78.0
1558 Female, age 85, left hemisphere 136.9
1550 Male, age 61, left hemisphere 118.1
1559 Female, age 85, right hemisphere 117.3
1551 Male, age 61, right hemisphere 100.6
1555 Male, age 74, right hemisphere 79.1
1557 Female, age 94, right hemisphere 70.2
1554 Male, age 74, left hemisphere 63.6
1556 Female, age 94, left hemisphere 62.7
1552 Male, age 75, left hemisphere 50.4
1553 Male, age 75, right hemisphere 46.3
1561 Female, age 67, right hemisphere 45.5
1560 Female, age 67, left hemisphere 45.1
Superior frontal gyrus
nTPM: 82.6
1569 Female, age 85, left hemisphere 132.8
1570 Female, age 85, right hemisphere 115.3
1562 Male, age 61, left hemisphere 105.0
1563 Male, age 61, right hemisphere 87.9
1566 Male, age 74, right hemisphere 80.9
1567 Female, age 94, left hemisphere 73.9
1564 Male, age 75, left hemisphere 64.3
1565 Male, age 75, right hemisphere 61.4
1568 Female, age 94, right hemisphere 61.2
1571 Female, age 67, right hemisphere 42.7
Temporal cortex
nTPM: 78.8
1596 Female, age 85, right hemisphere 103.3
1595 Female, age 94, right hemisphere 90.1
1594 Female, age 94, left hemisphere 87.1
1593 Male, age 74, right hemisphere 76.7
1592 Male, age 74, left hemisphere 74.1
1590 Male, age 61, right hemisphere 66.8
1591 Male, age 75, right hemisphere 53.8
Ventrolateral prefrontal cortex
nTPM: 72.0
1455 Female, age 85, right hemisphere 107.3
1454 Female, age 94, left hemisphere 85.3
1453 Male, age 74, right hemisphere 84.1
1452 Male, age 74, left hemisphere 81.3
1457 Female, age 67, right hemisphere 52.3
1456 Female, age 67, left hemisphere 47.9
1451 Male, age 75, right hemisphere 45.7
Ventromedial prefrontal cortex
nTPM: 92.6
1436 Female, age 85, left hemisphere 183.7
1432 Male, age 61, left hemisphere 106.1
1437 Female, age 85, right hemisphere 105.2
1433 Male, age 61, right hemisphere 88.0
1435 Female, age 94, right hemisphere 81.0
1434 Male, age 75, right hemisphere 43.7
1438 Female, age 67, left hemisphere 40.4

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 152.7
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 137.9
Samples: 233

Max nTPM: 257.1
Min nTPM: 36.2
Std nTPM: 42.0
Median nTPM: 135.7
GTEX-12WSI-0011-R3a-SM-GJ3QB 50-59 years, male 257.1
GTEX-13O3O-0011-R3b-SM-5KM3R 60-69 years, female 232.8
GTEX-11GS4-0011-R3b-SM-GJ3RI 60-69 years, male 232.1
GTEX-1E1VI-0011-R3a-SM-9OSWH 50-59 years, male 231.4
GTEX-1C6WA-0011-R3a-SM-9OSVP 60-69 years, male 231.2
GTEX-11DYG-0011-R3b-SM-GI4X7 60-69 years, male 226.5
GTEX-ZZPT-0011-R3a-SM-GOQYT 50-59 years, male 223.7
GTEX-UTHO-0011-R3A-SM-3GIK8 60-69 years, male 218.9
GTEX-13N1W-0011-R3a-SM-5MR5E 70-79 years, male 214.5
GTEX-11DXY-0011-R3a-SM-GIN8U 60-69 years, male 214.4
GTEX-11GSO-0011-R3b-SM-57WB2 60-69 years, male 213.7
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Brain - Cortex
Average nTPM: 144.4
Samples: 270

Max nTPM: 273.7
Min nTPM: 59.8
Std nTPM: 38.1
Median nTPM: 144.4
GTEX-1EMGI-3026-SM-7P8P6 60-69 years, male 273.7
GTEX-Z93S-2926-SM-57WB9 50-59 years, male 254.4
GTEX-X4XY-3026-SM-EWRM9 60-69 years, male 254.1
GTEX-13O3O-3126-SM-5KM3H 60-69 years, female 235.5
GTEX-144GL-3026-SM-5Q5CW 50-59 years, male 224.8
GTEX-UTHO-3026-SM-3GAFB 60-69 years, male 222.9
GTEX-14DAQ-3126-SM-62LDS 60-69 years, female 217.1
GTEX-NL3H-2526-SM-HM8V4 60-69 years, male 216.9
GTEX-11GS4-3126-SM-5A5LH 60-69 years, male 216.5
GTEX-Y8DK-0826-SM-4TT3T 60-69 years, male 215.4
GTEX-1PPGY-3126-SM-EXUSR 60-69 years, male 214.3
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Brain - Frontal Cortex (BA9)
Average nTPM: 152.7
Samples: 269

Max nTPM: 310.8
Min nTPM: 38.3
Std nTPM: 44.0
Median nTPM: 154.9
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 310.8
GTEX-1QMI2-0011-R10a-SM-F3428 60-69 years, male 287.3
GTEX-11GS4-0011-R10a-SM-GJ3RD 60-69 years, male 254.5
GTEX-14BMV-0011-R10b-SM-G8W82 50-59 years, male 249.7
GTEX-13NYS-0011-R10a-SM-5MR4S 60-69 years, male 248.7
GTEX-ZAK1-0011-R10a-SM-H7OGG 50-59 years, female 242.7
GTEX-13N1W-0011-R10b-SM-5MR4H 70-79 years, male 241.6
GTEX-NL3H-0011-R10A-SM-2I3E9 60-69 years, male 241.6
GTEX-1E1VI-0011-R10b-SM-ARU8F 50-59 years, male 235.7
GTEX-1QP6S-0011-R10a-SM-F341V 40-49 years, male 234.4
GTEX-13RTJ-0011-R10b-SM-5O9CW 60-69 years, male 232.4
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