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BETA
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EVOLUTIONARY PONS Show tissue menu
BRAIN66 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM10 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS
MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:1089.9 nTPM
FANTOM5:2807.1 Scaled Tags Per Million
Macaque:902.6 nTPM
Mouse:356.1 nTPM
Rat:737.7 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1089.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 640.9
2301 Female, age 85, both hemispheres 794.4
2188 Female, age 91, both hemispheres 652.5
1984 Male, age 76, both hemispheres 642.1
2090 Male, age 80, both hemispheres 474.7
Dorsal cochlear nucleus
nTPM: 640.9
2802 Male, age 74, right hemisphere 915.2
2187 Female, age 91, both hemispheres 678.1
2370 Male, age 61, both hemispheres 554.2
2058 Male, age 76, both hemispheres 553.4
2378 Male, age 80, both hemispheres 503.8
Dorsal tegmental nucleus
nTPM: 615.8
2326 Male, age 74, both hemispheres 704.7
1936 Male, age 76, left hemisphere 627.7
2083 Male, age 80, both hemispheres 614.9
2358 Male, age 61, both hemispheres 515.9
Dorsolateral tegmental area
nTPM: 558.7
2654 Male, age 80, both hemispheres 664.7
2360 Male, age 74, both hemispheres 650.6
2751 Female, age 85, both hemispheres 579.1
2141 Male, age 76, both hemispheres 491.9
2337 Male, age 61, both hemispheres 407.5
Kolliker-Fuse nucleus
nTPM: 739.9
2163 Male, age 80, both hemispheres 846.3
2793 Female, age 91, left hemisphere 798.3
2315 Male, age 76, right hemisphere 575.0
Lateral lemniscal nuclei
nTPM: 986.1
2169 Male, age 76, both hemispheres 1219.3
2036 Male, age 80, both hemispheres 1128.5
2453 Male, age 74, right hemisphere 1019.8
2746 Female, age 85, left hemisphere 868.2
2320 Female, age 91, left hemisphere 694.6
Lateral parabrachial nucleus
nTPM: 727.8
2139 Female, age 85, right hemisphere 1001.3
2013 Male, age 80, both hemispheres 743.2
2792 Male, age 76, both hemispheres 595.6
2790 Male, age 61, both hemispheres 571.0
Lateral vestibular nucleus
nTPM: 693.0
2184 Male, age 76, both hemispheres 752.4
2311 Male, age 80, both hemispheres 633.6
Locus coeruleus
nTPM: 705.9
2720 Male, age 74, both hemispheres 800.9
2123 Female, age 91, both hemispheres 791.2
2014 Male, age 55, unknown 755.6
2788 Male, age 74, unknown 723.0
2317 Female, age 72, unknown 671.0
2162 Male, age 80, both hemispheres 617.9
1980 Male, age 76, both hemispheres 581.8
Medial parabrachial nucleus
nTPM: 657.7
2854 Male, age 80, both hemispheres 917.8
2170 Female, age 91, both hemispheres 702.8
2786 Male, age 76, both hemispheres 594.2
2156 Male, age 61, both hemispheres 552.1
2463 Female, age 85, right hemisphere 521.6
Medial periolivary nuclei
nTPM: 951.2
2171 Female, age 85, both hemispheres 1418.8
2063 Male, age 76, both hemispheres 1205.6
2791 Male, age 74, right hemisphere 925.4
2458 Female, age 91, both hemispheres 624.0
2081 Male, age 80, both hemispheres 582.4
Motor facial nucleus
nTPM: 927.8
2062 Male, age 76, both hemispheres 1238.4
2697 Female, age 85, both hemispheres 1051.6
2327 Male, age 80, both hemispheres 958.3
2365 Male, age 74, right hemisphere 945.3
2795 Female, age 91, both hemispheres 762.6
2126 Male, age 61, both hemispheres 610.4
Motor trigeminal nucleus
nTPM: 691.1
2079 Male, age 80, both hemispheres 853.0
2560 Male, age 74, both hemispheres 817.8
2309 Male, age 76, both hemispheres 633.8
2321 Female, age 91, both hemispheres 597.4
2335 Male, age 61, both hemispheres 553.7
Nuclei of the trapezoid body
nTPM: 1046.1
2159 Male, age 61, both hemispheres 1320.2
2735 Female, age 85, both hemispheres 1299.8
1983 Male, age 76, both hemispheres 1080.8
2166 Male, age 80, both hemispheres 834.6
2368 Female, age 91, both hemispheres 695.1
Nucleus raphe magnus
nTPM: 1089.9
2160 Male, age 61, both hemispheres 1443.6
2172 Female, age 85, both hemispheres 1410.7
2455 Male, age 74, both hemispheres 1077.6
2051 Male, age 76, both hemispheres 961.7
2328 Male, age 80, both hemispheres 942.5
2459 Female, age 91, both hemispheres 703.0
Paramedian reticular nucleus
nTPM: 817.8
2050 Female, age 85, both hemispheres 1270.3
2052 Male, age 76, both hemispheres 698.2
2313 Male, age 61, both hemispheres 656.6
2057 Male, age 80, both hemispheres 646.1
Pedunculopontine tegmental nucleus
nTPM: 682.0
1921 Female, age 85, both hemispheres 694.3
2338 Male, age 61, both hemispheres 693.1
2334 Male, age 80, both hemispheres 658.7
Pontine nuclei
nTPM: 996.3
1863 Male, age 55, unknown 1353.0
2727 Male, age 61, right hemisphere 1347.9
2787 Female, age 85, both hemispheres 1198.6
1968 Male, age 76, left hemisphere 998.6
2109 Female, age 72, unknown 988.0
2454 Male, age 74, left hemisphere 794.2
2319 Female, age 91, both hemispheres 679.8
2115 Male, age 80, left hemisphere 609.9
Pontine raphe nucleus
nTPM: 785.3
2122 Female, age 85, midline 972.6
2853 Male, age 76, midline 598.0
Posteroventral cochlear nucleus
nTPM: 604.5
2752 Female, age 85, both hemispheres 825.4
2070 Male, age 76, both hemispheres 670.8
2371 Male, age 61, both hemispheres 591.0
2341 Male, age 80, both hemispheres 527.4
2135 Female, age 91, both hemispheres 407.9
Principal sensory trigeminal nucleus
nTPM: 934.0
2158 Male, age 61, both hemispheres 1199.6
2008 Male, age 80, left hemisphere 1127.0
2324 Male, age 76, both hemispheres 734.6
2367 Female, age 91, left hemisphere 674.9
Reticular pontine nucleus, caudal
nTPM: 776.3
2332 Male, age 80, right hemisphere 945.2
2092 Male, age 76, both hemispheres 848.1
2559 Male, age 74, both hemispheres 687.1
2457 Female, age 91, both hemispheres 624.8
Reticular pontine nucleus, oral
nTPM: 741.9
2012 Female, age 85, both hemispheres 935.9
2361 Male, age 74, both hemispheres 876.1
2366 Female, age 91, both hemispheres 666.1
1939 Male, age 80, both hemispheres 626.6
2167 Male, age 76, both hemispheres 605.0
Reticulotegmental nucleus
nTPM: 790.4
2325 Male, age 76, both hemispheres 876.8
2452 Male, age 74, both hemispheres 809.8
2322 Female, age 91, both hemispheres 756.3
2333 Male, age 80, both hemispheres 718.8
Spinal trigeminal nucleus, oral
nTPM: 682.1
2737 Female, age 85, both hemispheres 737.5
2164 Male, age 80, both hemispheres 669.1
1978 Male, age 76, both hemispheres 639.7
Subcoeruleus area
nTPM: 772.4
1958 Male, age 80, both hemispheres 979.5
2089 Male, age 76, left hemisphere 870.2
2323 Female, age 91, left hemisphere 782.6
2451 Male, age 74, both hemispheres 685.9
2369 Female, age 85, left hemisphere 543.9
Superior olive
nTPM: 919.0
1875 Female, age 85, both hemispheres 1264.1
2020 Male, age 76, both hemispheres 956.7
2364 Male, age 74, right hemisphere 847.9
2329 Male, age 80, right hemisphere 833.6
2561 Female, age 91, both hemispheres 692.5
Ventral periolivary nuclei
nTPM: 1032.8
2130 Female, age 85, both hemispheres 1324.0
2165 Male, age 80, both hemispheres 1068.9
2023 Male, age 76, both hemispheres 933.3
2794 Female, age 91, left hemisphere 805.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 788.7
2449 Male, age 74, both hemispheres 988.4
1959 Male, age 76, both hemispheres 951.2
2840 Female, age 85, both hemispheres 924.9
2161 Male, age 80, both hemispheres 779.4
2456 Female, age 91, both hemispheres 571.5
2359 Male, age 61, both hemispheres 516.6

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

2807.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1494.1
FF:10182-103D2 60 years, female 1741.2
FF:10165-103B3 76 years, female 1247.1
Pons
Scaled Tags Per Million: 2807.1
FF:10033-101E6 18-54 years, mixed 2807.1

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

902.6
Macaque sample Sample description nTPM
Pons
nTPM: 902.6
Samples: 2

Max nTPM: 1048.1
Min nTPM: 757.1
Sample A 1048.1
Sample B 757.1

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

356.1
Mouse sample Sample description nTPM
Pons
nTPM: 356.2
Samples: 4

Max nTPM: 388.4
Min nTPM: 325.7
Sample A 388.4
Sample B 325.7
Sample C 373.7
Sample D 336.8

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

737.7
Rat sample Sample description nTPM
Pons
nTPM: 737.7
Samples: 4

Max nTPM: 763.1
Min nTPM: 712.3
Sample A 718.6
Sample A 756.8
Sample A 712.3
Sample A 763.1

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