Brain tissue expression of RPL39 in medulla oblongata

MEDULLA OBLONGATA - Expression summary

Protein expressionⁱ

No data

RNA expressionⁱ

HPA Brain:	374.7	nTPM
FANTOM5:	20.5	Scaled Tags Per Million

Macaque:	235.7	nTPM
Mouse:	78.9	nTPM
Rat:	5.8	nTPM
Pig:	1.0	nTPM

MEDULLA OBLONGATA - SINGLE NUCLEI RNA EXPRESSIONⁱ RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right). - UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon - The BAR CHART* shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

SINGLE NUCLEI BRAIN - MEDULLA OBLONGATA, NEURONSⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Excitatory (VGLUT1) ETV1+ Z...
	c-2	Excitatory (VGLUT1) ETV1+ Z...
	c-3	Excitatory (VGLUT1) ETV1+ Z...
	c-4	Unassigned
	c-5	Excitatory (VGLUT1) ETV1+ Z...
	c-6	Inhibitory (GAD1/2) SLC6A5+
	c-7	Unassigned
	c-8	Excitatory (VGLUT1) ETV1+ Z...
	c-9	Excitatory (VGLUT1/2)
	c-10	Inhibitory (GAD1/2) SLC6A5+
	c-11	Inhibitory (GAD1/2) SLC6A5+...
	c-12	Excitatory (VGLUT2)
	c-13	Excitatory (VGLUT2)
	c-14	Inhibitory (GAD1/2) SLC6A5+...
	c-15	Inhibitory (GAD1/2) SLC6A5+...
	c-16	SST+ CALB1+ EBF1+
	c-17	Excitatory (VGLUT1/2)
	c-18	Inhibitory (GAD1/2) SLC6A5+...
	c-19	Inhibitory (GAD1/2) SLC6A5+...
	c-20	SST+ TAC3+ GRP+ SOX5+
	c-21	Inhibitory (GAD1/2) PVALB+ ...
	c-22	Inferior olive Excitatory (...
	c-23	Excitatory (VGLUT2)
	c-24	Excitatory (VGLUT2) TFAP2B+...
	c-25	Excitatory (VGLUT2)
	c-26	EBF1+ CALB1+
	c-27	SST+ TRH+ CALB1+
	c-28	Excitatory (VGLUT2) EBF1+
	c-29	Excitatory (VGLUT2) TH+ TFA...
	c-30	Monoaminergic Excitatory (V...
	c-31	Inhibitory (GAD1/2) PENK+ E...
	c-32	Excitatory (VGLUT2) SST+ TA...
	c-33	Inhibitory (GAD1/2) SLC6A5+
	c-34	Excitatory (VGLUT2) PVALB+
	c-35	Inhibitory (GAD2) SLC6A5+ N
	c-36	Excitatory (VGLUT2) GAL+ NO
	c-37	Serotonergic TPH2+ SLC6A4+
	c-38	Excitatory (VGLUT2) SLC5A7+...
	c-39	Cholinergic CHAT+ SLC5A7+ T...
	c-40	Excitatory (VGLUT2) MEIS2+
	c-41	Inhibitory (GAD1/2) SLC6A5+
	c-42	Inhibitory (GAD1/2) RORB+ K
	c-43	Inhibitory (GAD1/2) PENK+ ...
	c-44	LMX1A+
	c-45	Excitatory (VGLUT2) SST+ TA
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MEDULLA OBLONGATA, NON-NEURONALⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Oligodendrocytes
	c-2	Oligodendrocytes
	c-3	Oligodendrocytes
	c-4	Oligodendrocytes
	c-5	Oligodendrocytes
	c-6	Microglia
	c-7	Oligodendrocyte progenitor ...
	c-8	Oligodendrocytes
	c-9	Astrocytes (TTR+ CD44+)
	c-10	Oligodendrocytes
	c-11	Choroid plexus epithelial c...
	c-12	Astrocytes (TTR+ CD44+)
	c-13	Astrocytes (CD44+)
	c-14	Ependymal cells
	c-15	Astrocytes (TTR+ CD44+)
	c-16	Fibroblasts
	c-17	Astrocytes (TTR+ CD44+)
	c-18	Vascular endothelial cells
	c-19	Microglia
	c-20	Pericytes
	c-21	Lymphocytes
	c-22	Bergmann glia
	c-23	Macrophages
	c-24	Vascular smooth muscle cell
	c-25	Astrocyte & neuron doublets
	c-26	Ependymal cell & neuron dou...
	c-27	Immature oligodendrocytes
	c-28	Myelinating schwann cells
	c-29	Monocytes
	c-30	Oligodendrocyte progenitor ...
	c-31	Fibroblasts (BNC2+ KCNMA1+ ...
	c-32	Ependymal cell & oligodendr...
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MEDULLA OBLONGATA - HPA Brain RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	374.7

Sample id

Sample description

nTPM

Area postrema
nTPM: 296.3

2799	Male, age 61, both hemispheres	369.1
2306	Male, age 80, both hemispheres	304.3
2054	Male, age 76, both hemispheres	215.4

Dorsal medullary reticular nucleus
nTPM: 278.7

2040	Female, age 85, both hemispheres	328.0
2373	Male, age 61, both hemispheres	304.9
2088	Male, age 76, both hemispheres	203.1

Dorsal motor vagal complex
nTPM: 279.7

2797	Male, age 61, both hemispheres	443.2
2807	Female, age 85, both hemispheres	351.8
2643	Male, age 74, both hemispheres	326.1
2133	Female, age 91, both hemispheres	284.2
2844	Male, age 55, unknown	236.0
2000	Male, age 74, unknown	212.8
2813	Female, age 72, unknown	194.8
2185	Male, age 76, both hemispheres	188.6

Gigantocellular reticular nuclei, medullary
nTPM: 280.2

2314	Male, age 61, both hemispheres	320.3
2387	Female, age 91, both hemispheres	318.2
1876	Female, age 85, both hemispheres	304.3
2022	Male, age 76, right hemisphere	275.7
2310	Male, age 80, both hemispheres	237.2
2462	Male, age 74, both hemispheres	225.3

Gigantocellular reticular nuclei, pars
nTPM: 216.2

2084	Female, age 85, both hemispheres	278.4
2706	Male, age 80, both hemispheres	227.1
2336	Male, age 61, both hemispheres	207.2
2330	Male, age 80, both hemispheres	192.1
2168	Male, age 76, both hemispheres	176.4

Inferior olive
nTPM: 296.0

2379	Male, age 80, both hemispheres	336.0
2178	Male, age 61, both hemispheres	313.6
2563	Male, age 74, both hemispheres	297.0
2085	Female, age 85, both hemispheres	291.0
2628	Female, age 91, both hemispheres	242.5

Lateral medullary reticular nucleus
nTPM: 299.5

2190	Female, age 85, both hemispheres	357.2
2852	Male, age 80, both hemispheres	350.7
2804	Female, age 91, both hemispheres	320.8
2305	Male, age 74, both hemispheres	277.9
2044	Male, age 76, both hemispheres	258.8
2374	Male, age 61, both hemispheres	231.5

Medial olivary nucleus
nTPM: 374.7

1943	Male, age 61, both hemispheres	442.9
1962	Male, age 76, both hemispheres	423.1
2138	Female, age 91, both hemispheres	318.9
2851	Male, age 80, both hemispheres	314.0

Medial vestibular nucleus
nTPM: 256.8

2803	Female, age 91, both hemispheres	327.0
2743	Female, age 85, both hemispheres	294.2
2093	Male, age 80, both hemispheres	254.9
2624	Male, age 61, both hemispheres	239.8
2801	Male, age 74, both hemispheres	218.8
2134	Male, age 76, both hemispheres	206.1

Motor hypoglossal nucleus
nTPM: 222.5

2132	Female, age 85, both hemispheres	312.3
2125	Female, age 91, both hemispheres	277.5
2182	Male, age 80, both hemispheres	218.6
2277	Male, age 76, both hemispheres	176.4
2461	Male, age 61, both hemispheres	127.7

Nucleus ambiguus
nTPM: 227.4

2071	Male, age 76, both hemispheres	312.9
2096	Female, age 85, both hemispheres	141.8

Nucleus cuneatus
nTPM: 278.6

2808	Female, age 85, both hemispheres	373.0
2380	Male, age 80, both hemispheres	352.5
2376	Male, age 61, both hemispheres	341.5
2564	Male, age 74, both hemispheres	289.4
2381	Male, age 80, both hemispheres	269.6
2562	Male, age 61, both hemispheres	268.5
2805	Female, age 91, both hemispheres	266.6
2100	Male, age 76, both hemispheres	175.9
2131	Male, age 76, both hemispheres	170.0

Nucleus gracilis
nTPM: 286.4

2382	Male, age 80, both hemispheres	311.0
2299	Female, age 85, both hemispheres	281.1
2627	Male, age 74, both hemispheres	266.9

Nucleus raphe obscurus
nTPM: 365.3

2845	Female, age 85, midline	382.5
2800	Male, age 61, midline	372.8
2142	Male, age 76, midline	340.5

Nucleus raphe pallidus
nTPM: 345.6

1924	Male, age 61, midline	466.0
2145	Male, age 76, midline	293.7
2183	Male, age 80, midline	277.0

Nucleus tractus solitarii
nTPM: 265.9

2144	Female, age 91, right hemisphere	373.9
2191	Female, age 85, both hemispheres	302.1
2656	Male, age 76, both hemispheres	203.6
2307	Male, age 80, both hemispheres	183.9

Parvicellular reticular nuclei
nTPM: 253.6

2119	Male, age 80, both hemispheres	304.3
2095	Male, age 76, both hemispheres	275.5
2558	Male, age 74, both hemispheres	181.1

Parvicellular reticular nuclei, medullary
nTPM: 255.1

2091	Female, age 85, both hemispheres	290.8
2189	Female, age 91, both hemispheres	255.8
2181	Male, age 80, left hemisphere	218.5

Peritrigeminal nucleus
nTPM: 331.8

2067	Female, age 85, both hemispheres	415.9
2136	Male, age 76, both hemispheres	327.8
2179	Male, age 61, both hemispheres	251.8

Prepositus hypoglossal nucleus
nTPM: 306.5

2855	Female, age 85, right hemisphere	329.3
2086	Male, age 80, both hemispheres	283.7

Spinal trigeminal nucleus, caudal
nTPM: 239.2

2390	Female, age 91, both hemispheres	257.5
2642	Male, age 74, both hemispheres	256.4
2308	Male, age 80, both hemispheres	254.9
2312	Male, age 61, both hemispheres	238.3
2447	Male, age 76, both hemispheres	189.0

Spinal trigeminal nucleus, interpolar
nTPM: 285.2

2033	Male, age 80, both hemispheres	336.9
2386	Female, age 85, both hemispheres	315.1
2066	Male, age 76, right hemisphere	282.2
2389	Female, age 91, both hemispheres	282.2
2625	Male, age 61, both hemispheres	209.5

Spinal vestibular nucleus
nTPM: 310.9

2384	Male, age 74, both hemispheres	407.4
2806	Female, age 85, both hemispheres	334.6
2780	Male, age 80, both hemispheres	303.4
2796	Male, age 61, both hemispheres	299.6
2748	Male, age 76, both hemispheres	260.7
2186	Female, age 91, both hemispheres	259.8

Superior vestibular nucleus
nTPM: 317.3

2015	Male, age 80, both hemispheres	355.8
2383	Male, age 74, both hemispheres	335.6
2061	Male, age 76, both hemispheres	260.4

Ventral medullary reticular nucleus
nTPM: 284.0

2372	Male, age 61, both hemispheres	349.0
2060	Male, age 76, both hemispheres	219.0

Ventrolateral medulla, A1-C1 cell groups
nTPM: 326.3

2118	Male, age 80, both hemispheres	390.2
2741	Female, age 85, both hemispheres	332.1
2302	Female, age 91, both hemispheres	311.0
1986	Male, age 76, both hemispheres	304.4
2180	Male, age 61, both hemispheres	293.6

MEDULLA OBLONGATA - FANTOM5 CAGEⁱ

Max subtype Scaled Tags Per Millionⁱ Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.	20.5

FANTOM5 sample id

Sample description

Scaled Tags Per Million

Medulla oblongata
Scaled Tags Per Million: 20.5

FF:10174-103C3	60 years, female	30.8
FF:10155-103A2	76 years, female	21.1
FF:10038-101F2	18-64 years, mixed	9.7

MEDULLA OBLONGATA - Macaque RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	235.7

Macaque sample

Sample description

nTPM

Medulla oblongata
nTPM: 235.7

Samples: 1

Max nTPM: 235.7
Min nTPM: 235.7

Sample A

235.7

MEDULLA OBLONGATA - Pig RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	1.0

Pig sample

Sample description

nTPM

Medulla oblongata
nTPM: 1.1

Samples: 4

Max nTPM: 2.9
Min nTPM: 0.0

Sample A	Female	1.3
Sample B	Female	0.0
Sample C	Male	2.9
Sample D	Male	0.0

MEDULLA OBLONGATA - Mouse RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	78.9

Mouse sample

Sample description

nTPM

Medulla oblongata
nTPM: 78.9

Samples: 4

Max nTPM: 107.4
Min nTPM: 64.6

Sample A		107.4
Sample B		70.1
Sample C		73.6
Sample D		64.6

MEDULLA OBLONGATA - Rat RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	5.8

Rat sample

Sample description

nTPM

Medulla oblongata
nTPM: 5.8

Samples: 4

Max nTPM: 6.3
Min nTPM: 5.5

Sample A		5.6
Sample A		5.7
Sample A		6.3
Sample A		5.5