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EVOLUTIONARY PONS Show tissue menu
BRAIN67 EYE3 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER2 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM8 BREAST & FEMALE REPRODUCTIVE SYSTEM9 MUSCLE & VASCULAR TISSUE11 CONNECTIVE & SOFT TISSUE14 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS
MIDDLE TEMPORAL GYRUS MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL CORTEX
SEPTUM SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD WHITE MATTER
CORNEA LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS PENIS PROSTATE SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:2560.9 nTPM
FANTOM5:33.1 Scaled Tags Per Million
Macaque:4.8 nTPM
Pig:1934.0 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2560.9
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 2382.7
2090 Male, age 80, both hemispheres 2864.3
2188 Female, age 91, both hemispheres 2726.3
2301 Female, age 85, both hemispheres 2452.5
1984 Male, age 76, both hemispheres 1487.9
Dorsal cochlear nucleus
nTPM: 2418.2
2802 Male, age 74, right hemisphere 2963.2
2187 Female, age 91, both hemispheres 2574.2
2378 Male, age 80, both hemispheres 2394.1
2370 Male, age 61, both hemispheres 2263.7
2058 Male, age 76, both hemispheres 1895.8
Dorsal tegmental nucleus
nTPM: 2181.7
2358 Male, age 61, both hemispheres 2604.4
2326 Male, age 74, both hemispheres 2388.9
2083 Male, age 80, both hemispheres 2140.2
1936 Male, age 76, left hemisphere 1593.6
Dorsolateral tegmental area
nTPM: 2260.8
2337 Male, age 61, both hemispheres 3555.2
2654 Male, age 80, both hemispheres 2406.2
2751 Female, age 85, both hemispheres 2241.3
2360 Male, age 74, both hemispheres 1938.8
2141 Male, age 76, both hemispheres 1162.8
Kolliker-Fuse nucleus
nTPM: 2051.7
2793 Female, age 91, left hemisphere 2356.3
2163 Male, age 80, both hemispheres 2178.5
2315 Male, age 76, right hemisphere 1620.3
Lateral lemniscal nuclei
nTPM: 1640.3
2453 Male, age 74, right hemisphere 2028.1
2746 Female, age 85, left hemisphere 1875.0
2320 Female, age 91, left hemisphere 1609.4
2036 Male, age 80, both hemispheres 1410.5
2169 Male, age 76, both hemispheres 1278.3
Lateral parabrachial nucleus
nTPM: 1928.1
2792 Male, age 76, both hemispheres 2260.8
2013 Male, age 80, both hemispheres 2231.9
2790 Male, age 61, both hemispheres 1783.9
2139 Female, age 85, right hemisphere 1435.6
Lateral vestibular nucleus
nTPM: 2166.3
2311 Male, age 80, both hemispheres 2497.3
2184 Male, age 76, both hemispheres 1835.3
Locus coeruleus
nTPM: 1437.8
2720 Male, age 74, both hemispheres 1824.4
2014 Male, age 55, unknown 1621.3
2123 Female, age 91, both hemispheres 1532.1
2162 Male, age 80, both hemispheres 1476.8
1980 Male, age 76, both hemispheres 1329.3
2317 Female, age 72, unknown 1305.6
2788 Male, age 74, unknown 975.0
Medial parabrachial nucleus
nTPM: 2086.1
2170 Female, age 91, both hemispheres 2995.8
2854 Male, age 80, both hemispheres 2306.7
2463 Female, age 85, right hemisphere 2084.3
2156 Male, age 61, both hemispheres 1523.6
2786 Male, age 76, both hemispheres 1520.2
Medial periolivary nuclei
nTPM: 1944.2
2081 Male, age 80, both hemispheres 2445.0
2458 Female, age 91, both hemispheres 2308.7
2791 Male, age 74, right hemisphere 1864.8
2063 Male, age 76, both hemispheres 1655.9
2171 Female, age 85, both hemispheres 1446.8
Motor facial nucleus
nTPM: 1857.6
2126 Male, age 61, both hemispheres 2326.3
2697 Female, age 85, both hemispheres 2101.1
2795 Female, age 91, both hemispheres 2064.4
2365 Male, age 74, right hemisphere 1965.9
2062 Male, age 76, both hemispheres 1387.4
2327 Male, age 80, both hemispheres 1300.7
Motor trigeminal nucleus
nTPM: 2041.5
2321 Female, age 91, both hemispheres 2618.8
2560 Male, age 74, both hemispheres 2223.3
2335 Male, age 61, both hemispheres 2155.4
2079 Male, age 80, both hemispheres 1612.6
2309 Male, age 76, both hemispheres 1597.4
Nuclei of the trapezoid body
nTPM: 1723.0
2166 Male, age 80, both hemispheres 2192.3
2368 Female, age 91, both hemispheres 1846.8
1983 Male, age 76, both hemispheres 1741.5
2159 Male, age 61, both hemispheres 1537.0
2735 Female, age 85, both hemispheres 1297.3
Nucleus raphe magnus
nTPM: 1603.0
2459 Female, age 91, both hemispheres 1971.7
2051 Male, age 76, both hemispheres 1861.2
2455 Male, age 74, both hemispheres 1698.2
2328 Male, age 80, both hemispheres 1561.9
2160 Male, age 61, both hemispheres 1298.9
2172 Female, age 85, both hemispheres 1226.4
Paramedian reticular nucleus
nTPM: 2098.3
2052 Male, age 76, both hemispheres 2385.8
2057 Male, age 80, both hemispheres 2114.0
2050 Female, age 85, both hemispheres 1970.3
2313 Male, age 61, both hemispheres 1923.0
Pedunculopontine tegmental nucleus
nTPM: 1961.1
2338 Male, age 61, both hemispheres 2809.3
2334 Male, age 80, both hemispheres 1792.7
1921 Female, age 85, both hemispheres 1281.3
Pontine nuclei
nTPM: 1844.1
2319 Female, age 91, both hemispheres 2543.5
2115 Male, age 80, left hemisphere 2303.6
2454 Male, age 74, left hemisphere 2181.9
2109 Female, age 72, unknown 2069.0
1968 Male, age 76, left hemisphere 1606.0
1863 Male, age 55, unknown 1456.6
2727 Male, age 61, right hemisphere 1363.3
2787 Female, age 85, both hemispheres 1228.6
Pontine raphe nucleus
nTPM: 1356.0
2122 Female, age 85, midline 1378.5
2853 Male, age 76, midline 1333.4
Posteroventral cochlear nucleus
nTPM: 2560.9
2341 Male, age 80, both hemispheres 3269.1
2135 Female, age 91, both hemispheres 3162.5
2371 Male, age 61, both hemispheres 2608.7
2070 Male, age 76, both hemispheres 1894.8
2752 Female, age 85, both hemispheres 1869.5
Principal sensory trigeminal nucleus
nTPM: 1781.1
2367 Female, age 91, left hemisphere 2257.2
2324 Male, age 76, both hemispheres 1859.0
2158 Male, age 61, both hemispheres 1557.4
2008 Male, age 80, left hemisphere 1450.8
Reticular pontine nucleus, caudal
nTPM: 1857.9
2559 Male, age 74, both hemispheres 2613.1
2457 Female, age 91, both hemispheres 1988.7
2092 Male, age 76, both hemispheres 1593.8
2332 Male, age 80, right hemisphere 1236.3
Reticular pontine nucleus, oral
nTPM: 1889.5
2361 Male, age 74, both hemispheres 2389.3
1939 Male, age 80, both hemispheres 1937.9
2366 Female, age 91, both hemispheres 1898.4
2012 Female, age 85, both hemispheres 1672.0
2167 Male, age 76, both hemispheres 1549.9
Reticulotegmental nucleus
nTPM: 1927.6
2452 Male, age 74, both hemispheres 2346.5
2322 Female, age 91, both hemispheres 2203.0
2333 Male, age 80, both hemispheres 1806.5
2325 Male, age 76, both hemispheres 1354.6
Spinal trigeminal nucleus, oral
nTPM: 1795.7
2164 Male, age 80, both hemispheres 2139.3
2737 Female, age 85, both hemispheres 1721.7
1978 Male, age 76, both hemispheres 1526.1
Subcoeruleus area
nTPM: 1776.3
2369 Female, age 85, left hemisphere 2417.5
2451 Male, age 74, both hemispheres 2025.3
1958 Male, age 80, both hemispheres 1790.6
2323 Female, age 91, left hemisphere 1337.8
2089 Male, age 76, left hemisphere 1310.1
Superior olive
nTPM: 1835.4
2561 Female, age 91, both hemispheres 2231.7
2364 Male, age 74, right hemisphere 1971.4
2020 Male, age 76, both hemispheres 1881.7
2329 Male, age 80, right hemisphere 1665.0
1875 Female, age 85, both hemispheres 1427.1
Ventral periolivary nuclei
nTPM: 1717.0
2794 Female, age 91, left hemisphere 2070.7
2023 Male, age 76, both hemispheres 2000.9
2165 Male, age 80, both hemispheres 1723.7
2130 Female, age 85, both hemispheres 1072.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 1911.8
2359 Male, age 61, both hemispheres 2247.7
2456 Female, age 91, both hemispheres 2120.3
2840 Female, age 85, both hemispheres 1975.8
2161 Male, age 80, both hemispheres 1943.7
2449 Male, age 74, both hemispheres 1732.9
1959 Male, age 76, both hemispheres 1450.4

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

33.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 33.1
FF:10182-103D2 60 years, female 40.4
FF:10165-103B3 76 years, female 25.9
Pons
Scaled Tags Per Million: 22.4
FF:10033-101E6 18-54 years, mixed 22.4

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

4.8
Macaque sample Sample description nTPM
Pons
nTPM: 4.8
Samples: 2

Max nTPM: 9.6
Min nTPM: 0.0
Sample A 9.6
Sample B 0.0

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1934.0
Pig sample Sample description nTPM
Pons
nTPM: 1934.0
Samples: 3

Max nTPM: 2520.9
Min nTPM: 1628.2
Sample A Female 1628.2
Sample B Female 1653.0
Sample C Male 2520.9

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