Single cell type - RBAK-RBAKDN - The Human Protein Atlas

RBAK-RBAKDN

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RBAK-RBAKDN

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	RBAK-RBAKDN
Gene descriptionⁱ Full gene name according to HGNC.	RBAK-RBAKDN readthrough
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	2

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.
Single cell type expression clusterⁱ The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity.	Non-specific - Mixed function (mainly)
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected.	Group enriched (Podocytes, Distal convoluted tubule cells, Renal connecting tubule cells, Proximal tubule cells, Loop of Henle epithelial cells, Renal collecting duct principal cells, Renal collecting duct intercalated cells, Papillary tip epithelial cells, Late primary spermatocytes, Early spermatids)
Tau specificity scoreⁱ Tau specificity score is a numerical indicator of the specificity of the gene expression across cells or tissues. The value ranges from 0 and 1, where 0 indicates identical expression across all cells/tissue types, while 1 indicates expression in a single cell/tissue type.	0.75
Brain cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell cluster types based on snRNA-seq data from brain samples. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. "cell type" refer to one of the 34 cluster names used to summarize the 2.5 million cells included in the brain cell representation.	Not available
Immune cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected.	Not detected in immune cells
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence (neXtProt evidence);and a Human Protein Atlas antibody- or RNA based score (HPA evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable.	Evidence at transcript level

ASSAYSⁱ

Single cell type

Expression clustering

SINGLE CELL TYPESⁱ A summary of normalized single cell RNA (nCPM) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common. * Single nuclei
Single cell type groups RNA single cell type group specificity: Group enriched (Renal nephron cells, Ductal cells, Spermatogenic cell types)

EXPRESSION CLUSTERING & CORRELATIONⁱ

RBAK-RBAKDN is part of cluster 29 Non-specific - Mixed function with confidenceⁱ 1
131 genes in cluster

Go to interactive expression cluster page

15 nearest neighbours based on single cell RNA expression

Neighbourⁱ Gene name according to HGNC.	Descriptionⁱ Gene description according to HGNC.	Correlationⁱ Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.	Clusterⁱ ID of the expression cluster of the neighboring gene.
CCDC180	Coiled-coil domain containing 180	0.8421	29
ENSG00000281039	Novel protein	0.8327	29
GPRASP1	G protein-coupled receptor associated sorting protein 1	0.8304	29
WDR27	WD repeat domain 27	0.8283	29
ANAPC10	Anaphase promoting complex subunit 10	0.8248	29
SOCS5	Suppressor of cytokine signaling 5	0.8246	29
ENSG00000254692	Novel protein	0.8100	29
KRIT1	KRIT1 ankyrin repeat containing	0.7986	29
TESK2	Testis associated actin remodelling kinase 2	0.7767	29
ZNF512	Zinc finger protein 512	0.7756	29
LINC02210-CRHR1	LINC02210-CRHR1 readthrough	0.7687	29
COX15	Cytochrome c oxidase assembly homolog COX15	0.7571	29
DET1	DET1 partner of COP1 E3 ubiquitin ligase	0.7567	29
UMAD1	UBAP1-MVB12-associated (UMA) domain containing 1	0.7559	29
ZNF727	Zinc finger protein 727	0.7475	29

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut and Alice Wallenberg Foundation.

contact@proteinatlas.org

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