LINC02203
HPA
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  • LINC02203
SINGLE CELL SINGLE CELL TYPES EXPRESSION CLUSTER TISSUES Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND BLOOD BONE MARROW BRAIN BREAST COLON ENDOMETRIUM EPIDIDYMIS ESOPHAGUS
EYE FALLOPIAN TUBE HEART MUSCLE LIVER LUNG LYMPH NODE OVARY PANCREAS PITUITARY GLAND PLACENTA
PROSTATE RECTUM SALIVARY GLAND SKELETAL MUSCLE SKIN SMALL INTESTINE SPLEEN STOMACH TESTIS THYMUS
TONGUE URINARY BLADDER VASCULATURE
Single cell type
Bulk RNA deconvolution
Deep visual proteomics
Cell type
Single cell
Methods
Cell type
DVP
Methods
Cell type enrichment
Cell types
Methods
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

LINC02203
Gene descriptioni

Full gene name according to HGNC.

Long intergenic non-protein coding RNA 2203
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Membrane
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

1
HUMAN PROTEIN ATLAS INFORMATIONi

Summary of RNA expression and protein localization based on data generated within the Human Protein Atlas project.

Single cell type expression clusteri

The RNA data was used to cluster genes according to their expression across single cell types. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity.

Early spermatids - Flagellar development (mainly)
Single cell type specificityi

The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected.

Group enriched (Early spermatids, Late primary spermatocytes)
Tau specificity scorei

Tau specificity score is a numerical indicator of the specificity of the gene expression across cells or tissues. The value ranges from 0 and 1, where 0 indicates identical expression across all cells/tissue types, while 1 indicates expression in a single cell/tissue type.

0.98
Brain cell type specificityi

The RNA specificity category is based on mRNA expression levels in the analyzed cell cluster types based on snRNA-seq data from brain samples. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. "cell type" refer to one of the 34 cluster names used to summarize the 2.5 million cells included in the brain cell representation.

Cell type enhanced (Specialized neurotransmitter neurons)
Immune cell specificityi

The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected.

Not detected in immune cells
Protein evidencei

Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence (neXtProt evidence);and a Human Protein Atlas antibody- or RNA based score (HPA evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable.

Evidence at transcript level
ASSAYSi

Overview of the different datasets included in the Single Cell resource.

Single cell type
Expression clustering
SINGLE CELL TYPESi

A summary of normalized single cell RNA (nCPM) from all single cell types. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.

* Single nuclei
Single cell type groups
RNA single cell type group specificity: Cell type enriched (Spermatogenic cell types)
EXPRESSION CLUSTERING & CORRELATIONi

The RNA data was used to cluster genes according to their expression across samples. The resulting clusters have been manually annotated to describe common features in terms of function and specificity. The annotation of the cluster is displayed together with a confidence score of the gene's assignment to the cluster. The confidence is calculated as the fraction of times the gene was assigned to this cluster in repeated calculations and is reported between 0 to 1, where 1 is the highest possible confidence. The clustering results are shown in a UMAP, where the cluster this gene was assigned to is highlighted as a colored area in which most of the cluster genes reside. A table shows the 15 most similar genes in terms of expression profile.

LINC02203 is part of cluster 78 Early spermatids - Flagellar development with confidencei

Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. A confidence of 1 indicates that the gene was assigned to this cluster in all repeated clusterings.

1
239 genes in cluster
Go to interactive expression cluster page
15 nearest neighbours based on single cell RNA expression
Neighbouri

Gene name according to HGNC.

Descriptioni

Gene description according to HGNC.

Correlationi

Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.

Clusteri

ID of the expression cluster of the neighboring gene.

SPANXN5 SPANX family member N5 0.7986 78
SPATA46 Spermatogenesis associated 46 0.7590 78
FNDC11 Fibronectin type III domain containing 11 0.7234 78
FAM221B Family with sequence similarity 221 member B 0.7188 78
PDCL2 Phosducin like 2 0.7179 78
TEX33 Testis expressed 33 0.7175 78
SPACA4 Sperm acrosome associated 4 0.7098 78
ACTRT3 Actin related protein T3 0.6894 78
FAM209B Family with sequence similarity 209 member B 0.6820 78
PRSS54 Serine protease 54 0.6816 78
FAM209A Family with sequence similarity 209 member A 0.6814 78
ERICH2 Glutamate rich 2 0.6807 78
SPACA7 Sperm acrosome associated 7 0.6759 78
MS4A6E Membrane spanning 4-domains A6E 0.6736 78
FTMT Ferritin mitochondrial 0.6637 78

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