CCR7

TISSUE ATLAS

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Gene description

Chemokine (C-C motif) receptor 7

RNA tissue category

Mixed.

Protein summary

Detected at High or Medium expression level in 14 of 79 analyzed normal tissue cell types.

Protein expression

Lymphoid cells outside reaction centra, white pulp of spleen, myoepithelia and alveolar cells showed strong cytoplasmic and membranous positivity. Microvilli in placenta were moderately stained and cytotrophoblasts displayed membranous immunoreactivity. Keratinized layers of squamous epithelia, myoepithelial cells of breast and epididymis and peripheral nerves were distinctly stained. Remaining normal tissues were in general negative.

Protein class

Candidate cancer biomarkers, CD markers, G-protein coupled receptors, Potential transmembrane proteins

Protein evidence

Medium

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

CAB003796