A recent addition to the single cell type section are the ciliated cells in the fallopian tubes. Ciliated cells in the fallopian tube play an important role in the female reproductive system, facilitating successful fertilization and transport of gametes. This time, we focus on the elevated expression of the genes forkhead box J1 (FOXJ1) and dynein axonemal intermediate chain 2 (DNAI2)...Read more

In a study published in Nature Communications, the expression of all human protein-coding genes in more than 1,000 human cell lines representing 27 cancer types was investigated using genome-wide transcriptomics analysis...Read more

In this image of the month we focus on the microtubules and the protein CAMSAP2. Microtubules are filaments that, together with the other components of the cytoskeleton, provide structure and shape to our cells. They also play important roles in intracellular transport, cell division, as well as the formation of cilia and flagella. Microtubules are formed by the polymerization and lateral association of alpha - and beta-tubulin proteins into a hollow tubelike filament. Due to the end-to-end linear arrangement of the α- and β-tubulin dimers the filaments have a polarity, which is crucial for their dynamics and their biological functions ( Akhmanova and Steinmetz, 2015)...Read more

In this movie light-sheet microscopy has been used to visualize the mouse peripheral nervous system in 3D with Prof Patrik Ernfors explaining how this system develops, functions and is organized...Read more

In a recent publication in Journal of Proteome Research antibodies from the Human Protein Atlas was utilized in a microarray format for protein profiling of 960 serum samples within the context of rheumatic diseases...Read more