|
|
Citing the Human Protein Atlas
To cite us, please use:
The Human Protein Atlas
|
Uhlen M, Oksvold P, Fagerberg L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf C, Wester K, Hober S, Wernerus H, Björling L, Ponten F.
Towards a knowledge-based Human Protein Atlas.
Nat Biotechnol. 2010 28(12):1248-50.
PubMed: 21139605 DOI: 10.1038/nbt1210-1248
|
The original Human Protein Atlas publication
|
Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F.
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Mol Cell Proteomics. 2005 4(12):1920-32.
PubMed: 16127175 DOI: 10.1074/mcp.M500279-MCP200
|
Pathology
|
Pontén F, Jirström K, Uhlen M.
The Human Protein Atlas - a tool for pathology.
J Pathol. 2008 216(4):387-93.
PubMed: 18853439 DOI: 10.1002/path.2440
|
Global analysis of the proteome
|
Lundberg E, Fagerberg L, Klevebring D, Matic I, Geiger T, Cox J, Algenäs C, Lundeberg J, Mann M, Uhlen M.
Defining the transcriptome and proteome in three functionally different human cell lines.
Mol Syst Biol. 2010 6:450.
PubMed: 21179022 DOI: 10.1038/msb.2010.106
|
|
|
Pontén F, Gry M, Fagerberg L, Lundberg E, Asplund A, Berglund L, Oksvold P, Björling E, Hober S, Kampf C, Navani S, Nilsson P, Ottosson J, Persson A, Wernérus H, Wester K, Uhlén M.
A global view of protein expression in human cells, tissues, and organs.
Mol Syst Biol. 2009 5:337.
PubMed: 20029370 DOI: 10.1038/msb.2009.93
|
Publications
| 209 |
Danielsson F, Wiking M, Mahdessian D, Skogs M, Ait Blal H, Hjelmare M, Stadler C, Uhlén M, Lundberg E.
RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins.
J Proteome Res. 2013 12(1):299-307.
PubMed: 23227862 DOI: 10.1021/pr3009308
|
| 208 |
Liu S, Im H, Bairoch A, Cristofanilli M, Chen R, Deutsch EW, Dalton S, Fenyo D, Fanayan S, Gates C, Gaudet P, Hincapie M, Hanash S, Kim H, Jeong SK, Lundberg E, Mias G, Menon R, Mu Z, Nice E, Paik YK, Uhlen M, Wells L, Wu SL, Yan F, Zhang F, Zhang Y, Snyder M, Omenn GS, Beavis RC, Hancock WS.
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.
J Proteome Res. 2013 12(1):45-57.
PubMed: 23259914 DOI: 10.1021/pr300985j
|
| 207 |
Peña C, Céspedes MV, Lindh MB, Kiflemariam S, Mezheyeuski A, Edqvist PH, Hägglöf C, Birgisson H, Bojmar L, Jirström K, Sandström P, Olsson E, Veerla S, Gallardo A, Sjöblom T, Chang AC, Reddel RR, Mangues R, Augsten M, Ostman A.
STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer.
Cancer Res. 2013 73(4):1287-1297.
PubMed: 23243022 DOI: 10.1158/0008-5472.CAN-12-1875
|
| 206 |
Osterholm C, Folkersen L, Lengquist M, Pontén F, Renné T, Li J, Hedin U.
Increased expression of heparanase in symptomatic carotid atherosclerosis.
Atherosclerosis. 2013 226(1):67-73.
PubMed: 23137827 DOI: 10.1016/j.atherosclerosis.2012.09.030
|
| 205 |
Botling J, Edlund K, Lohr M, Hellwig B, Holmberg L, Lambe M, Berglund A, Ekman S, Bergqvist M, Pontén F, König A, Fernandes O, Karlsson M, Helenius G, Karlsson C, Rahnenführer J, Hengstler JG, Micke P.
Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation.
Clin Cancer Res. 2013 19(1):194-204.
PubMed: 23032747 DOI: 10.1158/1078-0432.CCR-12-1139
|
| 204 |
Lohr M, Edlund K, Botling J, Hammad S, Hellwig B, Othman A, Berglund A, Lambe M, Holmberg L, Ekman S, Bergqvist M, Pontén F, Cadenas C, Marchan R, Hengstler JG, Rahnenführer J, Micke P.
The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer.
Cancer Lett. 2013 Epub ahead of print
PubMed: 23370224 DOI: 10.1016/j.canlet.2013.01.036
|
| 203 |
Hansson SF, Korsgren S, Pontén F, Korsgren O.
Enteroviruses and the pathogenesis of type 1 diabetes revisited: Cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins.
J Pathol. 2013 Epub ahead of print
PubMed: 23335350 DOI: 10.1002/path.4166
|
| 202 |
Bozóky B, Savchenko A, Csermely P, Korcsmáros T, Dúl Z, Pontén F, Székely L, Klein G.
Novel signatures of cancer-associated fibroblasts.
Int J Cancer. 2013 Epub ahead of print
PubMed: 23319410 DOI: 10.1002/ijc.28035
|
| 201 |
Larance M, Kirkwood KJ, Xirodimas DP, Lundberg E, Uhlen M, Lamond AI.
Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
Mol Cell Proteomics. 2012 11(3):M111.014407.
PubMed: 22038470 DOI: 10.1074/mcp.M111.014407
|
| 200 |
Dengjel J, Høyer-Hansen M, Nielsen MO, Eisenberg T, Harder LM, Schandorff S, Farkas T, Kirkegaard T, Becker AC, Schroeder S, Vanselow K, Lundberg E, Nielsen MM, Kristensen AR, Akimov V, Bunkenborg J, Madeo F, Jäättelä M, Andersen JS.
Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.
Mol Cell Proteomics. 2012 11(3):M111.014035.
PubMed: 22311637 DOI: 10.1074/mcp.M111.014035
|
| 199 |
Bock T, Moest H, Omasits U, Dolski S, Lundberg E, Frei A, Hofmann A, Bausch-Fluck D, Jacobs A, Krayenbuehl N, Uhlen M, Aebersold R, Frei K, Wollscheid B.
Proteomic analysis reveals drug accessible cell surface N-glycoproteins of primary and established glioblastoma cell lines.
J Proteome Res. 2012 11(10):4885-93.
PubMed: 22909291 DOI: 10.1021/pr300360a
|
| 198 |
Solnestam BW, Stranneheim H, Hällman J, Käller M, Lundberg E, Lundeberg J, Akan P.
Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs.
BMC Genomics. 2012 13():574.
PubMed: 23110385 DOI: 10.1186/1471-2164-13-574
|
| 197 |
Akan P, Alexeyenko A, Costea PI, Hedberg L, Solnestam BW, Lundin S, Hällman J, Lundberg E, Uhlén M, Lundeberg J.
Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines.
Genome Med. 2012 4(11):86.
PubMed: 23158748 DOI: 10.1186/gm387
|
| 196 |
Li J, Shariff A, Wiking M, Lundberg E, Rohde GK, Murphy RF.
Estimating microtubule distributions from 2D immunofluorescence microscopy images reveals differences among human cultured cell lines.
PLoS One. 2012 7(11):e50292.
PubMed: 23209697 DOI: 10.1371/journal.pone.0050292
|
| 195 |
Li J, Newberg JY, Uhlén M, Lundberg E, Murphy RF.
Automated analysis and reannotation of subcellular locations in confocal images from the human protein atlas.
PLoS One. 2012 7(11):e50514.
PubMed: 23226299 DOI: 10.1371/journal.pone.0050514
|
| 194 |
Kampf C, Bergman J, Oksvold P, Asplund A, Navani S, Wiking M, Lundberg E, Uhlén M, Ponten F.
A tool to facilitate clinical biomarker studies--a tissue dictionary based on the Human Protein Atlas.
BMC Med. 2012 10():103.
PubMed: 22971420 DOI: 10.1186/1741-7015-10-103
|
| 193 |
Sillars-Hardebol AH, Carvalho B, Beliën JA, de Wit M, Delis-van Diemen PM, Tijssen M, van de Wiel MA, Pontén F, Meijer GA, Fijneman RJ.
CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression.
Cell Oncol (Dordr). 2012 35(4):293-300.
PubMed: 22711543 DOI: 10.1007/s13402-012-0088-2
|
| 192 |
Dieterich LC, Mellberg S, Langenkamp E, Zhang L, Zieba A, Salomäki H, Teichert M, Huang H, Edqvist PH, Kraus T, Augustin HG, Olofsson T, Larsson E, Söderberg O, Molema G, Pontén F, Georgii-Hemming P, Alafuzoff I, Dimberg A.
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.
J Pathol. 2012 228(3):378-90.
PubMed: 22786655 DOI: 10.1002/path.4072
|
| 191 |
Edqvist PH, Niklasson M, Vidal-Sanz M, Hallböök F, Forsberg-Nilsson K.
Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.
PLoS One. 2012 7(8):e42488.
PubMed: 22880002 DOI: 10.1371/journal.pone.0042488
|
| 190 |
Fagerberg L, Oksvold P, Skogs M, Algenäs C, Lundberg E, Pontén F, Sivertsson A, Odeberg J, Klevebring D, Kampf C, Asplund A, Sjöstedt E, Al-Khalili Szigyarto C, Edqvist PH, Olsson I, Rydberg U, Hudson P, Ottosson Takanen J, Berling H, Björling L, Tegel H, Rockberg J, Nilsson P, Navani S, Jirström K, Mulder J, Schwenk JM, Zwahlen M, Hober S, Forsberg M, von Feilitzen K, Uhlén M.
Contribution of Antibody-based Protein Profiling to the Human Chromosome-centric Proteome Project (C-HPP).
J Proteome Res. 2012 Epub ahead of print
PubMed: 23276153 DOI: 10.1021/pr300924j
|
| 189 |
Sjöberg R, Sundberg M, Gundberg A, Sivertsson A, Schwenk JM, Uhlén M, Nilsson P.
Validation of affinity reagents using antigen microarrays.
N Biotechnol. 2012 29(5):555-63.
PubMed: 22134247 DOI: 10.1016/j.nbt.2011.11.009
|
| 188 |
Arabi A, Ullah K, Branca RM, Johansson J, Bandarra D, Haneklaus M, Fu J, Ariës I, Nilsson P, Den Boer ML, Pokrovskaja K, Grandér D, Xiao G, Rocha S, Lehtiö J, Sangfelt O.
Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway.
Nat Commun. 2012 3():976.
PubMed: 22864569 DOI: 10.1038/ncomms1975
|
| 187 |
Medrek C, Pontén F, Jirström K, Leandersson K.
The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients.
BMC Cancer. 2012 12(1):306.
PubMed: 22824040 DOI: 10.1186/1471-2407-12-306
|
| 186 |
Smits A, Jin Z, Elsir T, Pedder H, Nistér M, Alafuzoff I, Dimberg A, Edqvist PH, Pontén F, Aronica E, Birnir B.
GABA-A Channel Subunit Expression in Human Glioma Correlates with Tumor Histology and Clinical Outcome.
PLoS One. 2012 7(5):e37041.
PubMed: 22615883 DOI: 10.1371/journal.pone.0037041
|
| 185 |
Asplund A, Edqvist PH, Schwenk JM, Pontén F.
Antibodies for profiling the human proteome- The Human Protein Atlas as a resource for cancer research.
Proteomics. 2012 Epub ahead of print
PubMed: 22623277 DOI: 10.1002/pmic.201100504
|
| 184 |
Wallgard E, Nitzsche A, Larsson J, Guo X, Dieterich LC, Dimberg A, Olofsson T, Pontén FC, Mäkinen T, Kalén M, Hellström M.
Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development.
Dev Dyn. 2012 241(4):770-86.
PubMed: 22354871 DOI: 10.1002/dvdy.23753
|
| 183 |
Lindskog C, Korsgren O, Pontén F, Eriksson JW, Johansson L, Danielsson A.
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
J Proteomics. 2012 75(9):2611-20.
PubMed: 22465717 DOI: 10.1016/j.jprot.2012.03.008
|
| 182 |
Li A, Ponten F, dos Remedios CG.
The interactome of LIM domain proteins: the contributions of LIM domain proteins to heart failure and heart development.
Proteomics. 2012 12(2):203-25.
PubMed: 22253135 DOI: 10.1002/pmic.201100492
|
| 181 |
Kiflemariam S, Andersson S, Asplund A, Pontén F, Sjöblom T.
Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers.
PLoS One. 2012 7(3):e32927.
PubMed: 22412953 DOI: 10.1371/journal.pone.0032927
|
| 180 |
Kampf C, Olsson I, Ryberg U, Sjöstedt E, Pontén F.
Production of tissue microarrays, immunohistochemistry staining and digitalization within the human protein atlas.
J Vis Exp. 2012 (63):.
PubMed: 22688270 DOI: 10.3791/3620
|
| 179 |
Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P.
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Int J Cancer. 2012 Epub ahead of print
PubMed: 22392539 DOI: 10.1002/ijc.27518
|
| 178 |
Samir R, Asplund A, Tot T, Pekar G, Hellberg D.
Oral contraceptive and progestin-only use correlates to tissue tumor marker expression in women with cervical intraepithelial neoplasia.
Contraception. 2012 85(3):288-93.
PubMed: 22067748 DOI: 10.1016/j.contraception.2011.09.001
|
| 177 |
Stadler C, Hjelmare M, Neumann B, Jonasson K, Pepperkok R, Uhlén M, Lundberg E
Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy.
J Proteomics. 2012 2236–2251
PubMed: 22361696 DOI: 10.1016/j.jprot.2012.01.030
|
| 176 |
Uhlén M, Oksvold P, Älgenäs C, Hamsten C, Fagerberg L, Klevebring D, Lundberg E, Odeberg J, Pontén F, Kondo T, Sivertsson Å.
Antibody-based protein profiling of the human chromosome 21.
Mol Cell Proteomics. 2012 11(3):M111.013458.
PubMed: 22042635 DOI: 10.1074/mcp.M111.013458
|
| 175 |
Sillars-Hardebol AH, Carvalho B, Beliën JA, de Wit M, Delis-van Diemen PM, Tijssen M, van de Wiel MA, Pontén F, Fijneman RJ, Meijer GA.
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
J Pathol. 2012 226(3):442-50.
PubMed: 22009326 DOI: 10.1002/path.2983
|
| 174 |
Häggmark A, Neiman M, Drobin K, Zwahlen M, Uhlén M, Nilsson P, Schwenk JM.
Classification of protein profiles from antibody microarrays using heat and detergent treatment.
N Biotechnol. 2012 29(5):564-70.
PubMed: 22023822 DOI: 10.1016/j.nbt.2011.10.005
|
| 173 |
Ahmad Y, Boisvert FM, Lundberg E, Uhlen M, Lamond AI.
Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.
Mol Cell Proteomics. 2012 11(3):M111.013680.
PubMed: 22002106 DOI: 10.1074/mcp.M111.013680
|
| 172 |
Alpár A, Attems J, Mulder J, Hökfelt T, Harkany T.
The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage.
Cell Signal. 2012 24(2):378-87.
PubMed: 21982882 DOI: 10.1016/j.cellsig.2011.09.028
|
| 171 |
Zeiler M, Straube WL, Lundberg E, Uhlen M, Mann M.
A Protein Epitope Signature Tag (PrEST) library allows SILAC-based absolute quantification and multiplexed determination of protein copy numbers in cell lines.
Mol Cell Proteomics. 2012 11(3):O111.009613.
PubMed: 21964433 DOI: 10.1074/mcp.O111.009613
|
| 170 |
Gantelius J, Bass T, Sjöberg R, Nilsson P, Andersson-Svahn H.
A lateral flow protein microarray for rapid and sensitive antibody assays.
Int J Mol Sci. 2011 12(11):7748-59.
PubMed: 22174629 DOI: 10.3390/ijms12117748
|
| 169 |
Ståhl PL, Stranneheim H, Asplund A, Berglund L, Pontén F, Lundeberg J.
Sun-induced nonsynonymous p53 mutations are extensively accumulated and tolerated in normal appearing human skin.
J Invest Dermatol. 2011 131(2):504-8.
PubMed: 20944651 DOI: 10.1038/jid.2010.302
|
| 168 |
Sillars-Hardebol AH, Carvalho B, Tijssen M, Beliën JA, de Wit M, Delis-van Diemen PM, Pontén F, van de Wiel MA, Fijneman RJ, Meijer GA.
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.
Gut. 2011 Epub ahead of print
PubMed: 22207630 DOI: 10.1136/gutjnl-2011-301153
|
| 167 |
Samir R, Asplund A, Tot T, Pekar G, Hellberg D.
High-risk HPV infection and CIN grade correlates to the expression of c-myc, CD4+, FHIT, E-cadherin, Ki-67, and p16INK4a.
J Low Genit Tract Dis. 2011 15(4):280-6.
PubMed: 21558960 DOI: 10.1097/LGT.0b013e318215170c
|
| 166 |
Lindström AK, Asplund A, Hellberg D.
Correlation between LRIG1 and LRIG2 expressions and expression of 11 tumor markers, with special reference to tumor suppressors, in CIN and normal cervical epithelium.
Gynecol Oncol. 2011 122(2):372-6.
PubMed: 21632100 DOI: 10.1016/j.ygyno.2011.04.049
|
| 165 |
Kato BS, Nicholson G, Neiman M, Rantalainen M, Holmes CC, Barrett A, Uhlen M, Nilsson P, Spector TD, Schwenk JM.
Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model.
Proteome Sci. 2011 9(1):73.
PubMed: 22093360 DOI: 10.1186/1477-5956-9-73
|
| 164 |
de Wit M, Jimenez CR, Carvalho B, Belien JA, Delis-van Diemen PM, Mongera S, Piersma SR, Vikas M, Navani S, Pontén F, Meijer GA, Fijneman RJ.
Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression.
Gut. 2011 Epub ahead of print
PubMed: 21890811 DOI: 10.1136/gutjnl-2011-300511
|
| 163 |
Gremel G, Ryan D, Rafferty M, Lanigan F, Hegarty S, Lavelle M, Murphy I, Unwin L, Joyce C, Faller W, McDermott EW, Sheahan K, Ponten F, Gallagher WM.
Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma.
Br J Cancer. 2011 105(4):565-74.
PubMed: 21730974 DOI: 10.1038/bjc.2011.249
|
| 162 |
Wallin U, Glimelius B, Jirström K, Darmanis S, Nong RY, Pontén F, Johansson C, Påhlman L, Birgisson H.
Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer.
Br J Cancer. 2011 104(10):1619-27.
PubMed: 21468045 DOI: 10.1038/bjc.2011.112
|
| 161 |
Hjelm B, Brennan DJ, Zendehrokh N, Eberhard J, Nodin B, Gaber A, Pontén F, Johannesson H, Smaragdi K, Frantz C, Hober S, Johnson LB, Påhlman S, Jirström K, Uhlen M.
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Proteomics Clin Appl. 2011 5(11-12):624-35.
PubMed: 21956899 DOI: 10.1002/prca.201100020
|
| 160 |
Jonsson L, Gaber A, Ulmert D, Uhlén M, Bjartell A, Jirström K.
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Diagn Pathol. 2011 6:91.
PubMed: 21955582 DOI: 10.1186/1746-1596-6-91
|
| 159 |
Nishibori Y, Katayama K, Parikka M, Oddsson A, Nukui M, Hultenby K, Wernerson A, He B, Ebarasi L, Raschperger E, Norlin J, Uhlén M, Patrakka J, Betsholtz C, Tryggvason K.
Glcci1 deficiency leads to proteinuria.
J Am Soc Nephrol. 2011 22(11):2037-46.
PubMed: 21949092 DOI: 10.1681/ASN.2010111147
|
| 158 |
Larsson A, Johansson ME, Wangefjord S, Gaber A, Nodin B, Kucharzewska P, Welinder C, Belting M, Eberhard J, Johnsson A, Uhlén M, Jirström K.
Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer.
Br J Cancer. 2011 105(5):666-72.
PubMed: 21829192 DOI: 10.1038/bjc.2011.295
|
| 157 |
Sistani L, Dunér F, Udumala S, Hultenby K, Uhlen M, Betsholtz C, Tryggvason K, Wernerson A, Patrakka J.
Pdlim2 is a novel actin-regulating protein of podocyte foot processes.
Kidney Int. 2011 80(10):1045-54.
PubMed: 21814175 DOI: 10.1038/ki.2011.231
|
| 156 |
Ehlén O, Nodin B, Rexhepaj E, Brändstedt J, Uhlén M, Alvarado-Kristensson M, Pontén F, Brennan DJ, Jirström K.
RBM3-Regulated Genes Promote DNA Integrity and Affect Clinical Outcome in Epithelial Ovarian Cancer.
Transl Oncol. 2011 4(4):212-21.
PubMed: 21804916
|
| 155 |
Jonsson L, Bergman J, Nodin B, Manjer J, Pontén F, Uhlén M, Jirström K.
Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: an analysis of 215 cases from the Malmö Diet and Cancer Study.
J Transl Med. 2011 9():114.
PubMed: 21777469 DOI: 10.1186/1479-5876-9-114
|
| 154 |
Legrain P, Aebersold R, Archakov A, Bairoch A, Bala K, Beretta L, Bergeron J, Borchers CH, Corthals GL, Costello CE, Deutsch EW, Domon B, Hancock W, He F, Hochstrasser D, Marko-Varga G, Salekdeh GH, Sechi S, Snyder M, Srivastava S, Uhlén M, Wu CH, Yamamoto T, Paik YK, Omenn GS.
The human proteome project: current state and future direction.
Mol Cell Proteomics. 2011 10(7):M111.009993.
PubMed: 21742803 DOI: 10.1074/mcp.M111.009993
|
| 153 |
Fagerberg L, Strömberg S, El-Obeid A, Gry M, Nilsson K, Uhlen M, Ponten F, Asplund A.
Large-scale protein profiling in human cell lines using antibody-based proteomics.
J Proteome Res. 2011 10(9):4066-75.
PubMed: 21726073 DOI: 10.1021/pr200259v
|
| 152 |
Larsson K, Hofström C, Lindskog C, Hansson M, Angelidou P, Hökfelt T, Uhlén M, Wernérus H, Gräslund T, Hober S.
Novel antigen design for the generation of antibodies to G-protein-coupled receptors.
J Immunol Methods. 2011 370(1-2):14-23.
PubMed: 21605562 DOI: 10.1016/j.jim.2011.05.001
|
| 151 |
Stanić D, Mulder J, Watanabe M, Hökfelt T.
Characterization of NPY Y2 receptor protein expression in the mouse brain. II. Coexistence with NPY, the Y1 receptor, and other neurotransmitter-related molecules.
J Comp Neurol. 2011 519(7):1219-57.
PubMed: 21452195 DOI: 10.1002/cne.22608
|
| 150 |
Lindfors C, Nilsson IA, Garcia-Roves PM, Zuberi AR, Karimi M, Donahue LR, Roopenian DC, Mulder J, Uhlén M, Ekström TJ, Davisson MT, Hökfelt TG, Schalling M, Johansen JE.
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.
Proc Natl Acad Sci U S A. 2011 108(44):18108-13.
PubMed: 22025706 DOI: 10.1073/pnas.1114863108
|
| 149 |
Colwill K, Persson H, Jarvik NE, Wyrzucki A, Wojcik J, Koide A, Kossiakoff AA, Koide S, Sidhu S, Dyson MR, Pershad K, Pavlovic JD, Karatt-Vellatt A, Schofield DJ, Kay BK, McCafferty J, Mersmann M, Meier D, Mersmann J, Helmsing S, Hust M, Dübel S, Berkowicz S, Freemantle A, Spiegel M, Sawyer A, Layton D, Nice E, Dai A, Rocks O, Williton K, Fellouse FA, Hersi K, Pawson T, Nilsson P, Sundberg M, Sjöberg R, Sivertsson Å, Schwenk JM, Takanen JO, Hober S, Uhlén M, Dahlgren LG, Flores A, Johansson I, Weigelt J, Crombet L, Loppnau P, Kozieradzki I, Cossar D, Arrowsmith CH, Edwards AM, Gräslund S.
A roadmap to generate renewable protein binders to the human proteome.
Nat Methods. 2011 8(7):551-8.
PubMed: 21572409 DOI: 10.1038/nmeth.1607
|
| 148 |
Schwenk JM, Nilsson P.
Assessment of antibody specificity using suspension bead arrays.
Methods Mol Biol. 2011 785:183-9.
PubMed: 21901600 DOI: 10.1007/978-1-61779-286-1_12
|
| 147 |
Neiman M, Hedberg JJ, Dönnes PR, Schuppe-Koistinen I, Hanschke S, Schindler R, Uhlén M, Schwenk JM, Nilsson P.
Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment.
J Proteome Res. 2011 10(11):4925-34.
PubMed: 21888404 DOI: 10.1021/pr200286c
|
| 146 |
Pontén F, Schwenk JM, Asplund A, Edqvist PH.
The Human Protein Atlas as a proteomic resource for biomarker discovery.
J Intern Med. 2011 270(5):428-46.
PubMed: 21752111 DOI: 10.1111/j.1365-2796.2011.02427.x
|
| 145 |
Tegel H, Yderland L, Boström T, Eriksson C, Ukkonen K, Vasala A, Neubauer P, Ottosson J, Hober S.
Parallel production and verification of protein products using a novel high-throughput screening method.
Biotechnol J. 2011 6(8):1018-25.
PubMed: 21681961 DOI: 10.1002/biot.201000430
|
| 144 |
Fagerberg L, Stadler C, Skogs M, Hjelmare M, Jonasson K, Wiking M, Abergh A, Uhlén M, Lundberg E.
Mapping the subcellular protein distribution in three human cell lines.
J Proteome Res. 2011 10(8):3766-77.
PubMed: 21675716 DOI: 10.1021/pr200379a
|
| 143 |
Magnusson K, de Wit M, Brennan DJ, Johnson LB, McGee SF, Lundberg E, Naicker K, Klinger R, Kampf C, Asplund A, Wester K, Gry M, Bjartell A, Gallagher WM, Rexhepaj E, Kilpinen S, Kallioniemi OP, Belt E, Goos J, Meijer G, Birgisson H, Glimelius B, Borrebaeck CA, Navani S, Uhlén M, O'Connor DP, Jirström K, Pontén F.
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Am J Surg Pathol. 2011 35(7):937-48.
PubMed: 21677534 DOI: 10.1097/PAS.0b013e31821c3dae
|
| 142 |
Hjelm B, Forsström B, Igel U, Johannesson H, Stadler C, Lundberg E, Ponten F, Sjöberg A, Rockberg J, Schwenk JM, Nilsson P, Johansson C, Uhlén M.
Generation of monospecific antibodies based on affinity capture of polyclonal antibodies.
Protein Sci. 2011 20(11):1824-35.
PubMed: 21898641 DOI: 10.1002/pro.716
|
| 141 |
Ström CE, Johansson F, Uhlén M, Szigyarto CA, Erixon K, Helleday T.
Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate.
Nucleic Acids Res. 2011 39(8):3166-75.
PubMed: 21183466 DOI: 10.1093/nar/gkq1241
|
| 140 |
Häggarth L, Hägglöf C, Jaraj SJ, Wester K, Pontén F, Ostman A, Egevad L.
Diagnostic biomarkers of prostate cancer.
Scand J Urol Nephrol. 2011 45(1):60-7.
PubMed: 21034352 DOI: 10.3109/00365599.2010.526141
|
| 139 |
Jaraj SJ, Augsten M, Häggarth L, Wester K, Pontén F, Ostman A, Egevad L.
GAD1 is a biomarker for benign and malignant prostatic tissue.
Scand J Urol Nephrol. 2011 45(1):39-45.
PubMed: 21091088 DOI: 10.3109/00365599.2010.521189
|
| 138 |
Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirström K, Magnusson K, Ebert BL, Pontén F, Weinberg RA, McAllister SS.
Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice.
J Clin Invest. 2011 121(2):784-99.
PubMed: 21266779 DOI: 10.1172/JCI43757
|
| 137 |
Xu X, Patrakka J, Sistani L, Uhlen M, Jalanko H, Betsholtz C, Tryggvason K.
Expression of novel podocyte-associated proteins sult1b1 and ankrd25.
Nephron Exp Nephrol. 2011 117(2):e39-46.
PubMed: 20720434 DOI: 10.1159/000320049
|
| 136 |
Falk R, Ramström M, Eriksson C, Uhlén M, Wernérus H, Hober S.
Targeted protein pullout from human tissue samples using competitive elution.
Biotechnol J. 2011 6(1):28-37.
PubMed: 21170982
|
| 135 |
Brennan DJ, Laursen H, O'Connor DP, Borgquist S, Uhlen M, Gallagher WM, Pontén F, Millikan RC, Rydén L, Jirström K.
Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.
Breast Cancer Res. 2011 13(1):R12.
PubMed: 21281480 DOI: 10.1186/bcr2820
|
| 134 |
Uhlen M, Svahn HA.
Affinity reagents for lab on chips.
Lab Chip. 2011 11(8):1417-9.
PubMed: 21286659 DOI: 10.1039/c1lc90005f
|
| 133 |
Mälarstig A, Silveira A, Wågsäter D, Öhrvik J, Bäcklund A, Samnegård A, Khademi M, Hellenius ML, Leander K, Olsson T, Uhlén M, de Faire U, Eriksson P, Hamsten A.
Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.
J Intern Med. 2011 270(3):229-36.
PubMed: 21332844 DOI: 10.1111/j.1365-2796.2011.02364.x
|
| 132 |
Schwenk JM, Nilsson P.
Antibody suspension bead arrays.
Methods Mol Biol. 2011 723:29-36.
PubMed: 21370057 DOI: 10.1007/978-1-61779-043-0_3
|
| 131 |
Ayoglu B, Häggmark A, Neiman M, Igel U, Uhlén M, Schwenk JM, Nilsson P.
Systematic antibody and antigen-based proteomic profiling with microarrays.
Expert Rev Mol Diagn. 2011 11(2):219-34.
PubMed: 21405972 DOI: 10.1586/erm.10.110
|
| 130 |
Navani, S.
The Human Protein Atlas
The Journal of Obstetrics and Gynaecology of India 2011 61(1):27-32.
DOI: 10.1007/s13224-011-0013-z
|
| 129 |
Tegel H, Ottosson J, Hober S.
Enhancing the protein production levels in Escherichia coli with a strong promoter.
FEBS J. 2011 278(5):729-39.
PubMed: 21205203 DOI: 10.1111/j.1742-4658.2010.07991.x
|
| 128 |
Gustavsson E, Ek S, Steen J, Kristensson M, Älgenäs C, Uhlén M, Wingren C, Ottosson J, Hober S, Borrebaeck CA.
Surrogate antigens as targets for proteome-wide binder selection.
N Biotechnol. 2011 28(4):302-11.
PubMed: 21232647 DOI: 10.1016/j.nbt.2010.12.005
|
| 127 |
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS.
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
EMBO J. 2011 30(8):1520-35.
PubMed: 21399614 DOI: 10.1038/emboj.2011.63
|
| 126 |
Samir R, Asplund A, Tot T, Pekar G, Hellberg D.
Tissue tumor marker expression in smokers, including serum cotinine concentrations, in women with cervical intraepithelial neoplasia or normal squamous cervical epithelium.
Am J Obstet Gynecol. 2010 202(6):579.e1-7.
PubMed: 20060094 DOI: 10.1016/j.ajog.2009.11.034
|
| 125 |
Samir R, Tot T, Asplund A, Pekar G, Hellberg D.
Increased serum progesterone and estradiol correlate to increased COX-2 tissue expression in cervical intraepithelial neoplasia.
Anticancer Res. 2010 30(4):1217-22.
PubMed: 20530431
|
| 124 |
Kronqvist N, Malm M, Rockberg J, Hjelm B, Uhlén M, Ståhl S, Löfblom J.
Staphylococcal surface display in combinatorial protein engineering and epitope mapping of antibodies.
Recent Pat Biotechnol. 2010 4(3):171-82.
PubMed: 21171954 DOI: 10.2174/187220810793611536
|
| 123 |
Klevebring D, Fagerberg L, Lundberg E, Emanuelsson O, Uhlén M, Lundeberg J.
Analysis of transcript and protein overlap in a human osteosarcoma cell line.
BMC Genomics. 2010 11:684.
PubMed: 21126332 DOI: 10.1186/1471-2164-11-684
|
| 122 |
Jonasson K, Berglund L, Uhlen M.
The 6th HUPO Antibody Initiative (HAI) workshop: sharing data about affinity reagents and other recent developments. September 2009, Toronto, Canada.
Proteomics. 2010 10(11):2066-8.
PubMed: 20514648 DOI: 10.1002/pmic.201090040
|
| 121 |
International Cancer Genome Consortium
International network of cancer genome projects.
Nature. 2010 464(7291):993-8.
PubMed: 20393554 DOI: 10.1038/nature08987
|
| 120 |
Mulder J, Spence L, Tortoriello G, Dinieri JA, Uhlén M, Shui B, Kotlikoff MI, Yanagawa Y, Aujard F, Hökfelt T, Hurd YL, Harkany T.
Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon.
Eur J Neurosci. 2010 31(12):2166-77.
PubMed: 20529129 DOI: 10.1111/j.1460-9568.2010.07275.x
|
| 119 |
Furusato B, Mohamed A, Uhlén M, Rhim JS.
CXCR4 and cancer.
Pathol Int. 2010 60(7):497-505.
PubMed: 20594270 DOI: 10.1111/j.1440-1827.2010.02548.x
|
| 118 |
Bourbeillon J, Orchard S, Benhar I, Borrebaeck C, de Daruvar A, Dübel S, Frank R, Gibson F, Gloriam D, Haslam N, Hiltker T, Humphrey-Smith I, Hust M, Juncker D, Koegl M, Konthur Z, Korn B, Krobitsch S, Muyldermans S, Nygren PA, Palcy S, Polic B, Rodriguez H, Sawyer A, Schlapshy M, Snyder M, Stoevesandt O, Taussig MJ, Templin M, Uhlen M, van der Maarel S, Wingren C, Hermjakob H, Sherman D.
Minimum information about a protein affinity reagent (MIAPAR).
Nat Biotechnol. 2010 28(7):650-3.
PubMed: 20622827 DOI: 10.1038/nbt0710-650
|
| 117 |
Gardberg M, Talvinen K, Kaipio K, Iljin K, Kampf C, Uhlen M, Carpén O.
Characterization of Diaphanous-related formin FMNL2 in human tissues.
BMC Cell Biol. 2010 11:55.
PubMed: 20633255 DOI: 10.1186/1471-2121-11-55
|
| 116 |
Uhlen M, Oksvold P, Fagerberg L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf C, Wester K, Hober S, Wernerus H, Björling L, Ponten F.
Towards a knowledge-based Human Protein Atlas.
Nat Biotechnol. 2010 28(12):1248-50.
PubMed: 21139605 DOI: 10.1038/nbt1210-1248
|
| 115 |
Lundberg E, Fagerberg L, Klevebring D, Matic I, Geiger T, Cox J, Algenäs C, Lundeberg J, Mann M, Uhlen M.
Defining the transcriptome and proteome in three functionally different human cell lines.
Mol Syst Biol. 2010 6:450.
PubMed: 21179022 DOI: 10.1038/msb.2010.106
|
| 114 |
Gry M, Oksvold P, Pontén F, Uhlén M.
Tissue-specific protein expression in human cells, tissues and organs.
J Proteomics Bioinform 2010 3(10):294-301.
DOI: 10.4172/jpb.1000153
|
| 113 |
Agnarsdóttir M, Sooman L, Bolander A, Strömberg S, Rexhepaj E, Bergqvist M, Ponten F, Gallagher W, Lennartsson J, Ekman S, Uhlen M, Hedstrand H.
SOX10 expression in superficial spreading and nodular malignant melanomas.
Melanoma Res. 2010 20(6):468-78.
PubMed: 20890226 DOI: 10.1097/CMR.0b013e3283403ccd
|
| 112 |
Brennan DJ, O'Connor DP, Rexhepaj E, Ponten F, Gallagher WM.
Antibody-based proteomics: fast-tracking molecular diagnostics in oncology.
Nat Rev Cancer. 2010 10(9):605-17.
PubMed: 20720569 DOI: 10.1038/nrc2902
|
| 111 |
Ehlén A, Brennan DJ, Nodin B, O'Connor DP, Eberhard J, Alvarado-Kristensson M, Jeffrey IB, Manjer J, Brändstedt J, Uhlén M, Pontén F, Jirström K.
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
J Transl Med. 2010 8:78.
PubMed: 20727170 DOI: 10.1186/1479-5876-8-78
|
| 110 |
Lindskog C, Asplund A, Engkvist M, Uhlén M, Korsgren O, Pontén F.
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Discov Med. 2010 9(49):565-78.
PubMed: 20587347
|
| 109 |
Blokzijl A, Friedman M, Pontén F, Landegren U.
Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine.
J Intern Med. 2010 268(3):232-45.
PubMed: 20695973 DOI: 10.1111/j.1365-2796.2010.02256.x
|
| 108 |
Ryan D, Rafferty M, Hegarty S, O'Leary P, Faller W, Gremel G, Bergqvist M, Agnarsdottir M, Strömberg S, Kampf C, Pontén F, Millikan RC, Dervan PA, Gallagher WM.
Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.
Pigment Cell Melanoma Res. 2010 23(4):542-53.
PubMed: 20465595 DOI: 10.1111/j.1755-148X.2010.00720.x
|
| 107 |
Brennan DJ, Brändstedt J, Rexhepaj E, Foley M, Pontén F, Uhlén M, Gallagher WM, O'Connor DP, O'Herlihy C, Jirstrom K.
Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
BMC Cancer. 2010 10:125.
PubMed: 20359358 DOI: 10.1186/1471-2407-10-125
|
| 106 |
Nord H, Segersten U, Sandgren J, Wester K, Busch C, Menzel U, Komorowski J, Dumanski JP, Malmström PU, Díaz de Ståhl T.
Focal amplifications are associated with high grade and recurrences in stage Ta bladder carcinoma.
Int J Cancer. 2010 126(6):1390-402.
PubMed: 19821490 DOI: 10.1002/ijc.24954
|
| 105 |
Borsics T, Lundberg E, Geerts D, Koomoa DL, Koster J, Wester K, Bachmann AS.
Subcellular distribution and expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in malignant glioma: Influence on cell survival and migration.
Cancer Sci. 2010 101(7):1624-31.
PubMed: 20412121 DOI: 10.1111/j.1349-7006.2010.01570.x
|
| 104 |
Lundberg E, Uhlén M.
Creation of an antibody-based subcellular protein atlas.
Proteomics. 2010 10(22):3984-96.
PubMed: 20648481 DOI: 10.1002/pmic.201000125
|
| 103 |
Schwenk JM, Igel U, Neiman M, Langen H, Becker C, Bjartell A, Ponten F, Wiklund F, Grönberg H, Nilsson P, Uhlen M.
Toward next generation plasma profiling via heat-induced epitope retrieval and array-based assays.
Mol Cell Proteomics. 2010 9(11):2497-507.
PubMed: 20682762 DOI: 10.1074/mcp.M110.001560
|
| 102 |
Rockberg J, Löfblom J, Hjelm B, Ståhl S, Uhlén M.
Epitope mapping using gram-positive surface display.
Curr Protoc Immunol. 2010 Chapter 9:Unit9.9.
PubMed: 20814943 DOI: 10.1002/0471142735.im0909s90
|
| 101 |
Tassidis H, Brokken LJ, Jirström K, Ehrnström R, Pontén F, Ulmert D, Bjartell A, Härkönen P, Wingren AG.
Immunohistochemical detection of tyrosine phosphatase SHP-1 predicts outcome after radical prostatectomy for localized prostate cancer.
Int J Cancer. 2010 126(10):2296-307.
PubMed: 19795453 DOI: 10.1002/ijc.24917
|
| 100 |
Holgersson G, Ekman S, Reizenstein J, Bergqvist M, Pontén F, Uhlén M, Magnusson K, Jonnalagadda P, Asplund A, Strömberg S, Linder A, Blomquist E, Liljeholm M, Lödén B, Hellström K, Bergström S.
Molecular profiling using tissue microarrays as a tool to identify predictive biomarkers in laryngeal cancer treated with radiotherapy.
Cancer Genomics Proteomics 2010 7(1):1-7.
PubMed: 20181625
|
| 99 |
Tegel H, Tourle S, Ottosson J, Persson A.
Increased levels of recombinant human proteins with the Escherichia coli strain Rosetta(DE3).
Protein Expr Purif. 2010 69(2):159-67.
PubMed: 19733669 DOI: 10.1016/j.pep.2009.08.017
|
| 98 |
Fagerberg L, Jonasson K, von Heijne G, Uhlén M, Berglund L.
Prediction of the human membrane proteome.
Proteomics. 2010 10(6):1141-9.
PubMed: 20175080 DOI: 10.1002/pmic.200900258
|
| 97 |
Schwenk JM, Igel U, Kato BS, Nicholson G, Karpe F, Uhlén M, Nilsson P.
Comparative protein profiling of serum and plasma using an antibody suspension bead array approach.
Proteomics. 2010 10(3):532-40.
PubMed: 19953555 DOI: 10.1002/pmic.200900657
|
| 96 |
Stadler C, Skogs M, Brismar H, Uhlén M, Lundberg E.
A single fixation protocol for proteome-wide immunofluorescence localization studies.
J Proteomics. 2010 73(6):1067-78.
PubMed: 19896565 DOI: 10.1016/j.jprot.2009.10.012
|
| 95 |
Gloriam DE, Orchard S, Bertinetti D, Björling E, Bongcam-Rudloff E, Borrebaeck CA, Bourbeillon J, Bradbury AR, de Daruvar A, Dübel S, Frank R, Gibson TJ, Gold L, Haslam N, Herberg FW, Hiltke T, Hoheisel JD, Kerrien S, Koegl M, Konthur Z, Korn B, Landegren U, Montecchi-Palazzi L, Palcy S, Rodriguez H, Schweinsberg S, Sievert V, Stoevesandt O, Taussig MJ, Ueffing M, Uhlén M, van der Maarel S, Wingren C, Woollard P, Sherman DJ, Hermjakob H.
A community standard format for the representation of protein affinity reagents.
Mol Cell Proteomics. 2010 9(1):1-10.
PubMed: 19674966 DOI: 10.1074/mcp.M900185-MCP200
|
| 94 |
Szigyarto CA, Sibbons P, Williams G, Uhlen M, Metcalfe SM.
The E3 ligase axotrophin/MARCH-7: protein expression profiling of human tissues reveals links to adult stem cells.
J Histochem Cytochem. 2010 58(4):301-8.
PubMed: 19901269 DOI: 10.1369/jhc.2009.954420
|
| 93 |
Hjelm B, Fernández CD, Löfblom J, Ståhl S, Johannesson H, Rockberg J, Uhlén M.
Exploring epitopes of antibodies toward the human tryptophanyl-tRNA synthetase.
N Biotechnol. 2010 27(2):129-37.
PubMed: 19913117 DOI: 10.1016/j.nbt.2009.11.001
|
| 92 |
Paavilainen L, Edvinsson A, Asplund A, Hober S, Kampf C, Pontén F, Wester K.
The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells.
J Histochem Cytochem. 2010 58(3):237-46.
PubMed: 19901271 DOI: 10.1369/jhc.2009.954321
|
| 91 |
Oberg F, Haseeb A, Ahnfelt M, Pontén F, Westermark B, El-Obeid A.
Herbal melanin activates TLR4/NF-kappaB signaling pathway.
Phytomedicine. 2009 16(5):477-84.
PubMed: 19103478 DOI: 10.1016/j.phymed.2008.10.008
|
| 90 |
Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes HW, Meyer HE, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang HG, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tárnok A, Taussig MJ, Thiel A, Thiery J, Ueffing M, Valet G, Vandekerckhove J, Wagener C, Wagner O, Schmitz G.
Approaching clinical proteomics: current state and future fields of application in cellular proteomics.
Cytometry A. 2009 75(10):816-32.
PubMed: 19739086 DOI: 10.1002/cyto.a.20779
|
| 89 |
Leja J, Essaghir A, Essand M, Wester K, Oberg K, Tötterman TH, Lloyd R, Vasmatzis G, Demoulin JB, Giandomenico V.
Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas.
Mod Pathol. 2009 22(2):261-72.
PubMed: 18953328 DOI: 10.1038/modpathol.2008.174
|
| 88 |
Qu M, Aronica E, Boer K, Fällmar D, Kumlien E, Nistér M, Wester K, Pontén F, Smits A.
DLG3/SAP102 protein expression in malformations of cortical development: a study of human epileptic cortex by tissue microarray.
Epilepsy Res. 2009 84(1):33-41.
PubMed: 19167192 DOI: 10.1016/j.eplepsyres.2008.12.004
|
| 87 |
Newberg JY, Li J, Rao A, Pontén F, Uhlén M, Lundberg E, Murphy RF.
Automated Analysis of Human Protein Atlas Immunofluorescence Images.
Proc IEEE Int Symp Biomed Imaging. 2009 5193229:1023-1026.
PubMed: 20628548 DOI: 10.1109/ISBI.2009.5193229
|
| 86 |
Gaber A, Johansson M, Stenman UH, Hotakainen K, Pontén F, Glimelius B, Bjartell A, Jirström K, Birgisson H.
High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer.
Br J Cancer. 2009 100(10):1540-8.
PubMed: 19384300 DOI: 10.1038/sj.bjc.6605047
|
| 85 |
Paulsson J, Sjöblom T, Micke P, Pontén F, Landberg G, Heldin CH, Bergh J, Brennan DJ, Jirström K, Ostman A.
Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer.
Am J Pathol. 2009 175(1):334-41.
PubMed: 19498003 DOI: 10.2353/ajpath.2009.081030
|
| 84 |
Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D, Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes HW, Meyer HE, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang HG, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tarnok A, Taussig MJ, Thiel A, Thiery J, Ueffing M, Valet G, Vandekerckhove J, Verhuven W, Wagener C, Wagner O, Schmitz G.
Approaching clinical proteomics: current state and future fields of application in fluid proteomics.
Clin Chem Lab Med. 2009 47(6):724-44.
PubMed: 19527139 DOI: 10.1515/CCLM.2009.167
|
| 83 |
Ghanipour A, Jirström K, Pontén F, Glimelius B, Påhlman L, Birgisson H.
The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer.
Cancer Epidemiol Biomarkers Prev. 2009 18(11):2949-56.
PubMed: 19900940 DOI: 10.1158/1055-9965.EPI-09-0456
|
| 82 |
Markljung E, Jiang L, Jaffe JD, Mikkelsen TS, Wallerman O, Larhammar M, Zhang X, Wang L, Saenz-Vash V, Gnirke A, Lindroth AM, Barrés R, Yan J, Strömberg S, De S, Pontén F, Lander ES, Carr SA, Zierath JR, Kullander K, Wadelius C, Lindblad-Toh K, Andersson G, Hjälm G, Andersson L.
ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth.
PLoS Biol. 2009 7(12):e1000256.
PubMed: 20016685 DOI: 10.1371/journal.pbio.1000256
|
| 81 |
Rimini R, Schwenk JM, Sundberg M, Sjöberg R, Klevebring D, Gry M, Uhlén M, Nilsson P.
Validation of serum protein profiles by a dual antibody array approach.
J Proteomics 2009 73(2):252-66.
PubMed: 19781670 DOI: 10.1016/j.jprot.2009.09.009
|
| 80 |
Joensson HN, Samuels ML, Brouzes ER, Medkova M, Uhlén M, Link DR, Andersson-Svahn H.
Detection and analysis of low-abundance cell-surface biomarkers using enzymatic amplification in microfluidic droplets.
Angew Chem Int Ed Engl. 2009 48(14):2518-21.
PubMed: 19235824 DOI: 10.1002/anie.200804326
|
| 79 |
Aebersold R, Auffray C, Baney E, Barillot E, Brazma A, Brett C, Brunak S, Butte A, Califano A, Celis J, Cufer T, Ferrell J, Galas D, Gallahan D, Gatenby R, Goldbeter A, Hace N, Henney A, Hood L, Iyengar R, Jackson V, Kallioniemi O, Klingmüller U, Kolar P, Kolch W, Kyriakopoulou C, Laplace F, Lehrach H, Marcus F, Matrisian L, Nolan G, Pelkmans L, Potti A, Sander C, Seljak M, Singer D, Sorger P, Stunnenberg H, Superti-Furga G, Uhlen M, Vidal M, Weinstein J, Wigle D, Williams M, Wolkenhauer O, Zhivotovsky B, Zinovyev A, Zupan B.
Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008).
Mol Oncol. 2009 3(1):9-17.
PubMed: 19383362 DOI: 10.1016/j.molonc.2008.11.003
|
| 78 |
Rockberg J, Schwenk JM, Uhlén M.
Discovery of epitopes for targeting the human epidermal growth factor receptor 2 (HER2) with antibodies.
Mol Oncol. 2009 3(3):238-47.
PubMed: 19393584 DOI: 10.1016/j.molonc.2009.01.003
|
| 77 |
Gry M, Rimini R, Strömberg S, Asplund A, Pontén F, Uhlén M, Nilsson P.
Correlations between RNA and protein expression profiles in 23 human cell lines.
BMC Genomics. 2009 10:365.
PubMed: 19660143 DOI: 10.1186/1471-2164-10-365
|
| 76 |
Jögi A, Brennan DJ, Rydén L, Magnusson K, Fernö M, Stål O, Borgquist S, Uhlen M, Landberg G, Påhlman S, Pontén F, Jirström K.
Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer.
Mod Pathol. 2009 22(12):1564-74.
PubMed: 19734850 DOI: 10.1038/modpathol.2009.124
|
| 75 |
Ahlin G, Hilgendorf C, Karlsson J, Szigyarto CA, Uhlén M, Artursson P.
Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs.
Drug Metab Dispos. 2009 37(12):2275-83.
PubMed: 19741037 DOI: 10.1124/dmd.109.028654
|
| 74 |
Vashisht AA, Zumbrennen KB, Huang X, Powers DN, Durazo A, Sun D, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, Wohlschlegel JA.
Control of iron homeostasis by an iron-regulated ubiquitin ligase.
Science. 2009 326(5953):718-21.
PubMed: 19762596 DOI: 10.1126/science.1176333
|
| 73 |
Mulder J, Zilberter M, Spence L, Tortoriello G, Uhlén M, Yanagawa Y, Aujard F, Hökfelt T, Harkany T.
Secretagogin is a Ca2+-binding protein specifying subpopulations of telencephalic neurons.
Proc Natl Acad Sci U S A. 2009 106(52):22492-7.
PubMed: 20018755 DOI: 10.1073/pnas.0912484106
|
| 72 |
Segersten MU, Edlund EK, Micke P, de la Torre M, Hamberg H, Edvinsson AE, Andersson SE, Malmström PU, Wester HK.
A novel strategy based on histological protein profiling in-silico for identifying potential biomarkers in urinary bladder cancer.
BJU Int. 2009 104(11):1780-5.
PubMed: 19522865 DOI: 10.1111/j.1464-410X.2009.08674.x
|
| 71 |
Pontén F, Gry M, Fagerberg L, Lundberg E, Asplund A, Berglund L, Oksvold P, Björling E, Hober S, Kampf C, Navani S, Nilsson P, Ottosson J, Persson A, Wernérus H, Wester K, Uhlén M.
A global view of protein expression in human cells, tissues, and organs.
Mol Syst Biol. 2009 5:337.
PubMed: 20029370 DOI: 10.1038/msb.2009.93
|
| 70 |
Rockberg J, Uhlén M.
Prediction of antibody response using recombinant human protein fragments as antigen.
Protein Sci. 2009 18(11):2346-55.
PubMed: 19760667 DOI: 10.1002/pro.245
|
| 69 |
Rodriguez H, Snyder M, Uhlén M, Andrews P, Beavis R, Borchers C, Chalkley RJ, Cho SY, Cottingham K, Dunn M, Dylag T, Edgar R, Hare P, Heck AJ, Hirsch RF, Kennedy K, Kolar P, Kraus HJ, Mallick P, Nesvizhskii A, Ping P, Pontén F, Yang L, Yates JR, Stein SE, Hermjakob H, Kinsinger CR, Apweiler R.
Recommendations from the 2008 International Summit on Proteomics Data Release and Sharing Policy: the Amsterdam principles.
J Proteome Res. 2009 8(7):3689-92.
PubMed: 19344107 DOI: 10.1021/pr900023z
|
| 68 |
Alimohammadi M, Dubois N, Sköldberg F, Hallgren A, Tardivel I, Hedstrand H, Haavik J, Husebye ES, Gustafsson J, Rorsman F, Meloni A, Janson C, Vialettes B, Kajosaari M, Egner W, Sargur R, Pontén F, Amoura Z, Grimfeld A, De Luca F, Betterle C, Perheentupa J, Kämpe O, Carel JC.
Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen.
Proc Natl Acad Sci U S A. 2009 106(11):4396-401.
PubMed: 19251657 DOI: 10.1073/pnas.0809986106
|
| 67 |
Strömberg S, Agnarsdóttir M, Magnusson K, Rexhepaj E, Bolander A, Lundberg E, Asplund A, Ryan D, Rafferty M, Gallagher WM, Uhlen M, Bergqvist M, Ponten F.
Selective expression of Syntaxin-7 protein in benign melanocytes and malignant melanoma.
J Proteome Res. 2009 8(4):1639-46.
PubMed: 19714869 DOI: 10.1021/pr800745e
|
| 66 |
Estigoy CB, Pontén F, Odeberg J, Herbert B, Guilhaus M, Charleston M, Ho JWK, Cameron D, dos Remedios CG.
Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts.
Biophys Rev 2009 1:43-49.
DOI: 10.1007/s12551-008-0007-y
|
| 65 |
Wensman H, Göransson H, Leuchowius KJ, Strömberg S, Pontén F, Isaksson A, Rutteman GR, Heldin NE, Pejler G, Hellmén E.
Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas.
Breast Cancer Res Treat. 2009 118(2):333-43.
PubMed: 19048371 DOI: 10.1007/s10549-008-0243-7
|
| 64 |
Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M.
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Mol Cell Proteomics. 2009 8(7):1612-22.
PubMed: 19351664 DOI: 10.1074/mcp.M800539-MCP200
|
| 63 |
Larsson K, Eriksson C, Schwenk JM, Berglund L, Wester K, Uhlén M, Hober S, Wernérus H.
Characterization of PrEST-based antibodies towards human Cytokeratin-17.
J Immunol Methods. 2009 342(1-2):20-32.
PubMed: 19108777 DOI: 10.1016/j.jim.2008.11.013
|
| 62 |
Steen J, Ramström M, Uhlén M, Hober S, Ottosson J.
Automated sample preparation method for mass spectrometry analysis on recombinant proteins.
J Chromatogr A. 2009 1216(20):4457-64.
PubMed: 19345368 DOI: 10.1016/j.chroma.2009.03.041
|
| 61 |
Tegel H, Steen J, Konrad A, Nikdin H, Pettersson K, Stenvall M, Tourle S, Wrethagen U, Xu L, Yderland L, Uhlén M, Hober S, Ottosson J.
High-throughput protein production - lessons from scaling up from 10 to 288 recombinant proteins per week.
Biotechnol J. 2009 4(1):51-7.
PubMed: 19039781 DOI: 10.1002/biot.200800183
|
| 60 |
Ramström M, Zuberovic A, Grönwall C, Hanrieder J, Bergquist J, Hober S.
Development of affinity columns for the removal of high-abundance proteins in cerebrospinal fluid.
Biotechnol Appl Biochem. 2009 52(Pt 2):159-66.
PubMed: 18412540 DOI: 10.1042/BA20080015
|
| 59 |
Koomoa DL, Go RC, Wester K, Bachmann AS.
Expression profile of PRAF2 in the human brain and enrichment in synaptic vesicles.
Neurosci Lett. 2008 436(2):171-6.
PubMed: 18395978 DOI: 10.1016/j.neulet.2008.03.030
|
| 58 |
Bolander A, Agnarsdóttir M, Strömberg S, Ponten F, Hesselius P, Uhlen M, Bergqvist M.
The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas.
Cancer Genomics Proteomics 2008 5(6):293-300.
PubMed: 19287070
|
| 57 |
Borgquist S, Djerbi S, Pontén F, Anagnostaki L, Goldman M, Gaber A, Manjer J, Landberg G, Jirström K.
HMG-CoA reductase expression in breast cancer is associated with a less aggressive phenotype and influenced by anthropometric factors.
Int J Cancer. 2008 123(5):1146-53.
PubMed: 18528862 DOI: 10.1002/ijc.23597
|
| 56 |
Borgquist S, Jögi A, Pontén F, Rydén L, Brennan DJ, Jirström K.
Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer.
Breast Cancer Res. 2008 10(5):R79.
PubMed: 18808688 DOI: 10.1186/bcr2146
|
| 55 |
Asplund A, Gry Björklund M, Sundquist C, Strömberg S, Edlund K, Ostman A, Nilsson P, Pontén F, Lundeberg J.
Expression profiling of microdissected cell populations selected from basal cells in normal epidermis and basal cell carcinoma.
Br J Dermatol. 2008 158(3):527-38.
PubMed: 18241271 DOI: 10.1111/j.1365-2133.2007.08418.x
|
| 54 |
Uhlen M.
A new era for proteomics research?
Genome Biol. 2008 9(11):325.
PubMed: 19014405 DOI: 10.1186/gb-2008-9-11-325
|
| 53 |
Uhlen M, Gräslund S, Sundström M.
A pilot project to generate affinity reagents to human proteins.
Nat Methods. 2008 5(10):854-5.
PubMed: 18825127 DOI: 10.1038/nmeth1008-854
|
| 52 |
Pontén F, Jirström K, Uhlen M.
The Human Protein Atlas - a tool for pathology.
J Pathol. 2008 216(4):387-93.
PubMed: 18853439 DOI: 10.1002/path.2440
|
| 51 |
Rockberg J, Löfblom J, Hjelm B, Uhlén M, Ståhl S.
Epitope mapping of antibodies using bacterial surface display.
Nat Methods. 2008 5(12):1039-45.
PubMed: 19029907 DOI: 10.1038/nmeth.1272
|
| 50 |
Berglund L, Björling E, Oksvold P, Fagerberg L, Asplund A, Szigyarto CA, Persson A, Ottosson J, Wernérus H, Nilsson P, Lundberg E, Sivertsson A, Navani S, Wester K, Kampf C, Hober S, Pontén F, Uhlén M.
A genecentric Human Protein Atlas for expression profiles based on antibodies.
Mol Cell Proteomics. 2008 7(10):2019-27.
PubMed: 18669619 DOI: 10.1074/mcp.R800013-MCP200
|
| 49 |
Björling E, Uhlén M.
Antibodypedia, a portal for sharing antibody and antigen validation data.
Mol Cell Proteomics. 2008 7(10):2028-37.
PubMed: 18667413 DOI: 10.1074/mcp.M800264-MCP200
|
| 48 |
Uhlén M, Hober S.
Generation and validation of affinity reagents on a proteome-wide level.
J Mol Recognit. 2008 22(2):57-64.
PubMed: 18546091 DOI: 10.1002/jmr.891
|
| 47 |
Lundberg E, Gry M, Oksvold P, Kononen J, Andersson-Svahn H, Pontén F, Uhlén M, Asplund A.
The correlation between cellular size and protein expression levels - normalization for global protein profiling.
J Proteomics. 2008 71(4):448-60.
PubMed: 18656560 DOI: 10.1016/j.jprot.2008.06.014
|
| 46 |
Schwenk JM, Gry M, Rimini R, Uhlén M, Nilsson P.
Antibody suspension bead arrays within serum proteomics.
J Proteome Res. 2008 7(8):3168-79.
PubMed: 18588325 DOI: 10.1021/pr700890b
|
| 45 |
Berglund L, Björling E, Jonasson K, Rockberg J, Fagerberg L, Al-Khalili Szigyarto C, Sivertsson A, Uhlén M.
A whole-genome bioinformatics approach to selection of antigens for systematic antibody generation.
Proteomics. 2008 8(14):2832-9.
PubMed: 18655051 DOI: 10.1002/pmic.200800203
|
| 44 |
Uhlén M.
Affinity as a tool in life science.
Biotechniques. 2008 44(5):649-54.
PubMed: 18474040 DOI: 10.2144/000112803
|
| 43 |
Paavilainen L, Wernérus H, Nilsson P, Uhlén M, Hober S, Wester K, Pontén F.
Evaluation of monospecific antibodies: a comparison study with commercial analogs using immunohistochemistry on tissue microarrays.
Appl Immunohistochem Mol Morphol. 2008 16(5):493-502.
PubMed: 18685494 DOI: 10.1097/PAI.0b013e31817c645e
|
| 42 |
Berglund L, Andrade J, Odeberg J, Uhlén M.
The epitope space of the human proteome.
Protein Sci. 2008 17(4):606-13.
PubMed: 18359855 DOI: 10.1110/ps.073347208
|
| 41 |
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H.
Toward a confocal subcellular atlas of the human proteome.
Mol Cell Proteomics. 2008 7(3):499-508.
PubMed: 18029348 DOI: 10.1074/mcp.M700325-MCP200
|
| 40 |
Björling E, Lindskog C, Oksvold P, Linné J, Kampf C, Hober S, Uhlén M, Pontén F.
A web-based tool for in silico biomarker discovery based on tissue-specific protein profiles in normal and cancer tissues.
Mol Cell Proteomics. 2008 7(5):825-44.
PubMed: 17913849 DOI: 10.1074/mcp.M700411-MCP200
|
| 39 |
Hober S, Uhlén M.
Human protein atlas and the use of microarray technologies.
Curr Opin Biotechnol. 2008 19(1):30-5.
PubMed: 18187316 DOI: 10.1016/j.copbio.2007.11.006
|
| 38 |
Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagné P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjernø K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Körner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Löbke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A.
Human Proteinpedia enables sharing of human protein data.
Nat Biotechnol. 2008 26(2):164-7.
PubMed: 18259167 DOI: 10.1038/nbt0208-164
|
| 37 |
Nestor M, Ekberg T, Dring J, van Dongen GA, Wester K, Tolmachev V, Anniko M.
Quantification of CD44v6 and EGFR expression in head and neck squamous cell carcinomas using a single-dose radioimmunoassay.
Tumour Biol. 2007 28(5):253-63.
PubMed: 17992053 DOI: 10.1159/000110898
|
| 36 |
Sundqvist G, Stenvall M, Berglund H, Ottosson J, Brumer H.
A general, robust method for the quality control of intact proteins using LC-ESI-MS.
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 852(1-2):188-94.
PubMed: 17267305 DOI: 10.1016/j.jchromb.2007.01.011
|
| 35 |
Alm T, Steen J, Ottosson J, Hober S.
High-throughput protein purification under denaturating conditions by the use of cation exchange chromatography.
Biotechnol J. 2007 2(6):709-16.
PubMed: 17492715 DOI: 10.1002/biot.200700060
|
| 34 |
Renberg B, Nordin J, Merca A, Uhlén M, Feldwisch J, Nygren PA, Karlström AE.
Affibody molecules in protein capture microarrays: evaluation of multidomain ligands and different detection formats.
J Proteome Res. 2007 6(1):171-9.
PubMed: 17203961 DOI: 10.1021/pr060316r
|
| 33 |
Mulder J, Wernérus H, Shi TJ, Pontén F, Hober S, Uhlén M, Hökfelt T.
Systematically generated antibodies against human gene products: high throughput screening on sections from the rat nervous system.
Neuroscience. 2007 146(4):1689-703.
PubMed: 17478047 DOI: 10.1016/j.neuroscience.2007.02.054
|
| 32 |
Orchard S, Heck A, Uhlen M, Ping P.
Publication Committee meeting. HUPO 5th annual World Congress. Long Beach, CA, USA 30 October 2006.
Proteomics. 2007 7(7):1009-11.
PubMed: 17340644 DOI: 10.1002/pmic.200700015
|
| 31 |
Falk R, Ramström M, Ståhl S, Hober S.
Approaches for systematic proteome exploration.
Biomol Eng. 2007 24(2):155-68.
PubMed: 17376740 DOI: 10.1016/j.bioeng.2007.01.001
|
| 30 |
Strömberg S, Björklund MG, Asplund C, Sköllermo A, Persson A, Wester K, Kampf C, Nilsson P, Andersson AC, Uhlen M, Kononen J, Ponten F, Asplund A.
A high-throughput strategy for protein profiling in cell microarrays using automated image analysis.
Proteomics. 2007 7(13):2142-50.
PubMed: 17549799 DOI: 10.1002/pmic.200700199
|
| 29 |
Uhlen M.
Mapping the human proteome using antibodies
Mol Cell Proteomics 2007 6(8):1455-6.
PubMed: 17703056
|
| 28 |
Bengtsson S, Krogh M, Szigyarto CA, Uhlen M, Schedvins K, Silfverswärd C, Linder S, Auer G, Alaiya A, James P.
Large-scale proteomics analysis of human ovarian cancer for biomarkers.
J Proteome Res. 2007 6(4):1440-50.
PubMed: 17315909 DOI: 10.1021/pr060593y
|
| 27 |
Lofblom J, Kronqvist N, Uhlen M, Stahl S, Wernerus H.
Optimization of electroporation-mediated transformation: Staphylococcus carnosus as model organism.
J Appl Microbiol 2007 102(3):736-47.
PubMed: 17309623 DOI: 10.1111/j.1365-2672.2006.03127.x
|
| 26 |
Lerner M, Corcoran M, Cepeda D, Nielsen ML, Zubarev R, Pontén F, Uhlén M, Hober S, Grandér D, Sangfelt O.
The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD.
Mol Biol Cell. 2007 18(5):1670-82.
PubMed: 17314412 DOI: 10.1091/mbc.E06-03-0248
|
| 25 |
Lundberg E, Sundberg M, Gräslund T, Uhlén M, Svahn HA.
A novel method for reproducible fluorescent labeling of small amounts of antibodies on solid phase.
J Immunol Methods. 2007 322(1-2):40-9.
PubMed: 17383674 DOI: 10.1016/j.jim.2007.01.023
|
| 24 |
Patrakka J, Xiao Z, Nukui M, Takemoto M, He L, Oddsson A, Perisic L, Kaukinen A, Szigyarto CA, Uhlén M, Jalanko H, Betsholtz C, Tryggvason K.
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and 2310066E14Rik.
J Am Soc Nephrol. 2007 18(3):689-97.
PubMed: 17251388 DOI: 10.1681/ASN.2006060675
|
| 23 |
Taussig MJ, Stoevesandt O, Borrebaeck CA, Bradbury AR, Cahill D, Cambillau C, de Daruvar A, Dubel S, Eichler J, Frank R, Gibson TJ, Gloriam D, Gold L, Herberg FW, Hermjakob H, Hoheisel JD, Joos TO, Kallioniemi O, Koegll M, Konthur Z, Korn B, Kremmer E, Krobitsch S, Landegren U, van der Maarel S, McCafferty J, Muyldermans S, Nygren PA, Palcy S, Pluckthun A, Polic B, Przybylski M, Saviranta P, Sawyer A, Sherman DJ, Skerra A, Templin M, Ueffing M, Uhlen M.
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome.
Nature Methods 2007 4(1):13-7.
PubMed: 17195019 DOI: 10.1038/nmeth0107-13
|
| 22 |
Schwenk JM, Lindberg J, Sundberg M, Uhlén M, Nilsson P.
Determination of binding specificities in highly multiplexed bead-based assays for antibody proteomics.
Mol Cell Proteomics. 2007 6(1):125-32.
PubMed: 17060675 DOI: 10.1074/mcp.T600035-MCP200
|
| 21 |
Söderberg O, Gullberg M, Jarvius M, Ridderstråle K, Leuchowius KJ, Jarvius J, Wester K, Hydbring P, Bahram F, Larsson LG, Landegren U.
Direct observation of individual endogenous protein complexes in situ by proximity ligation.
Nat Methods. 2006 3(12):995-1000.
PubMed: 17072308 DOI: 10.1038/nmeth947
|
| 20 |
Steen J, Uhlén M, Hober S, Ottosson J.
High-throughput protein purification using an automated set-up for high-yield affinity chromatography.
Protein Expr Purif. 2006 46(2):173-8.
PubMed: 16483795 DOI: 10.1016/j.pep.2005.12.010
|
| 19 |
Andrade J, Berglund L, Uhlén M, Odeberg J.
Using Grid technology for computationally intensive applied bioinformatics analyses.
In Silico Biol. 2006 6(6):495-504.
PubMed: 17518760
|
| 18 |
Persson A, Hober S, Uhlén M.
A human protein atlas based on antibody proteomics.
Curr Opin Mol Ther. 2006 8(3):185-90.
PubMed: 16774037
|
| 17 |
Ek S, Andréasson U, Hober S, Kampf C, Pontén F, Uhlén M, Merz H, Borrebaeck CA.
From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies.
Mol Cell Proteomics. 2006 5(6):1072-81.
PubMed: 16524965 DOI: 10.1074/mcp.M600077-MCP200
|
| 16 |
Eriksson C, Agaton C, Kånge R, Sundberg M, Nilsson P, Ek B, Uhlén M, Gustafsson M, Hober S.
Microfluidic analysis of antibody specificity in a compact disk format.
J Proteome Res. 2006 5(7):1568-74.
PubMed: 16823963 DOI: 10.1021/pr050447c
|
| 15 |
Haab BB, Paulovich AG, Anderson NL, Clark AM, Downing GJ, Hermjakob H, Labaer J, Uhlen M.
A reagent resource to identify proteins and peptides of interest for the cancer community: a workshop report.
Mol Cell Proteomics. 2006 5(10):1996-2007.
PubMed: 16867976 DOI: 10.1074/mcp.T600020-MCP200
|
| 14 |
Larsson K, Wester K, Nilsson P, Uhlén M, Hober S, Wernérus H.
Multiplexed PrEST immunization for high-throughput affinity proteomics.
J Immunol Methods. 2006 315(1-2):110-20.
PubMed: 16949094 DOI: 10.1016/j.jim.2006.07.014
|
| 13 |
Andersson AC, Strömberg S, Bäckvall H, Kampf C, Uhlen M, Wester K, Pontén F.
Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.
J Histochem Cytochem. 2006 54(12):1413-23.
PubMed: 16957166 DOI: 10.1369/jhc.6A7001.2006
|
| 12 |
Rada-Iglesias A, Wallerman O, Koch C, Ameur A, Enroth S, Clelland G, Wester K, Wilcox S, Dovey OM, Ellis PD, Wraight VL, James K, Andrews R, Langford C, Dhami P, Carter N, Vetrie D, Pontén F, Komorowski J, Dunham I, Wadelius C.
Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.
Hum Mol Genet. 2005 14(22):3435-47.
PubMed: 16221759 DOI: 10.1093/hmg/ddi378
|
| 11 |
Janzi M, Odling J, Pan-Hammarström Q, Sundberg M, Lundeberg J, Uhlén M, Hammarström L, Nilsson P.
Serum microarrays for large scale screening of protein levels.
Mol Cell Proteomics. 2005 4(12):1942-7.
PubMed: 16131484 DOI: 10.1074/mcp.M500213-MCP200
|
| 10 |
Nilsson P, Paavilainen L, Larsson K, Odling J, Sundberg M, Andersson AC, Kampf C, Persson A, Al-Khalili Szigyarto C, Ottosson J, Björling E, Hober S, Wernérus H, Wester K, Pontén F, Uhlen M.
Towards a human proteome atlas: high-throughput generation of mono-specific antibodies for tissue profiling.
Proteomics. 2005 5(17):4327-37.
PubMed: 16237735 DOI: 10.1002/pmic.200500072
|
| 9 |
Hedhammar M, Stenvall M, Lönneborg R, Nord O, Sjölin O, Brismar H, Uhlén M, Ottosson J, Hober S.
A novel flow cytometry-based method for analysis of expression levels in Escherichia coli, giving information about precipitated and soluble protein.
J Biotechnol. 2005 119(2):133-46.
PubMed: 15996784 DOI: 10.1016/j.jbiotec.2005.03.024
|
| 8 |
Stenvall M, Steen J, Uhlén M, Hober S, Ottosson J.
High-throughput solubility assay for purified recombinant protein immunogens.
Biochim Biophys Acta. 2005 1752(1):6-10.
PubMed: 16084133 DOI: 10.1016/j.bbapap.2005.07.002
|
| 7 |
Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F.
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Mol Cell Proteomics. 2005 4(12):1920-32.
PubMed: 16127175 DOI: 10.1074/mcp.M500279-MCP200
|
| 6 |
Lindskog M, Rockberg J, Uhlen M, Sterky F.
Selection of protein epitopes for antibody production
Biotechniques 2005 38(5):723-7.
PubMed: 15945371
|
| 5 |
Uhlen M, Ponten F.
Antibody-based proteomics for human tissue profiling.
Mol Cell Proteomics. 2005 4(4):384-93.
PubMed: 15695805 DOI: 10.1074/mcp.R500009-MCP200
|
| 4 |
Kampf C, Andersson A-C, Wester K, Björling E, Uhlen M, Ponten F
Antibody-based tissue profiling as a tool in clinical proteomics
Clin. Proteomics 2004 1(3-4):285-300.
DOI: 10.1385/CP:1:3-4:285
|
| 3 |
Agaton C, Uhlén M, Hober S.
Genome-based proteomics.
Electrophoresis. 2004 25(9):1280-8.
PubMed: 15174050 DOI: 10.1002/elps.200405846
|
| 2 |
Agaton C, Falk R, Hoiden Guthenberg I, Gostring L, Uhlen M, Hober S.
Selective enrichment of monospecific polyclonal antibodies for antibody-based proteomics efforts.
J Chromatogr A 2004 16;1043(1):33-40.
PubMed: 15317410
|
| 1 |
Agaton C, Galli J, Höidén Guthenberg I, Janzon L, Hansson M, Asplund A, Brundell E, Lindberg S, Ruthberg I, Wester K, Wurtz D, Höög C, Lundeberg J, Ståhl S, Pontén F, Uhlén M.
Affinity proteomics for systematic protein profiling of chromosome 21 gene products in human tissues.
Mol Cell Proteomics. 2003 2(6):405-14.
PubMed: 12796447 DOI: 10.1074/mcp.M300022-MCP200
|
|
|
|
|
|
|
