Previous news articles featured the history and technology behind two powerful tools for visualizing proteins in tissues: immunohistochemistry and microscopy. These tools are applied to investigate and answer a wide range of questions, both in healthcare and research. This article focuses on two applications related to lung cancer: diagnostics in clinical pathology and discovery of genes associated with prognosis...Read more
The advances in histology and cytology, and biology as a whole, wouldn't have been possible without the invention of the microscope. To enlarge objects multiple times, and to be able to study these objects much more closely has contributed a great deal to science, if not the most...Read more
A bit more than two decades ago, the first Diablo game was released to the world. A game about a lone hero tasked with bringing down Diablo, one of the lords of Hell. This month we highlight a namesake to this hellish lord of terror, the protein DIABLO...Read more
Immunohistochemistry was first described by Coons et al. in the beginning of the 1940s, where the authors used fluorescein-labeled antibodies to visualize bacterial antigens in infected tissues. Today, IHC plays a pivotal role in diagnostics and serves as an essential tool in research...Read more
Testicular cancer is a rare type of cancer. Most testis cancers are curable, even at an advanced stage. The cancer can be divided into essentially two categories: Seminoma and Non-seminomatous germ cell tumors. Based on transcriptomics data and clinical metadata we have been able to determine 57 genes associated with either favorable or unfavorable prognosis in testis cancer...Read more
September 30, 2018 - October 3, 2018
HPA Presence at HUPO 2018On Sunday Sept 30 (11am-12pm), Jochen Schwenk will be hosting a session on Antibody Validation.On Monday October 1, Cristina Al-Khalili Szigyarto will present "Antibodypedia - an open access resource of validated antibodies".On Wednesday October 3, Ragna Häussler will give a talk on "Elucidating changes in plasma protein profiles related to bariatric surgery: an IMI DIRECT study." At 10.30 am Emma Lundberg will present "Dissecting the spatiotemporal subcellular distribution of the human proteome".Peter Nilsson presents "Autoantigen Anoctamin 2 associates with increased risk for multiple sclerosis".At 14.30 pm Cecilia Lindskog Bergström will present "Integrated omics for spatial mapping of the human proteome - understanding the molecular repertoire in health and disease".
March 28, 2019 - March 29, 2019
On March 29th, 2019, Mathias Uhlén will give a keynote on "The Human Protein Atlas - implications for human biology, drug development and precision medicine" at the International Rouen P2M Symposium on Precision Medicine "Pathways to Precision Medicine".