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Facets of individual-specific health signatures

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Facets of individual-specific health signatures determined from longitudinal plasma proteome profilingProteins that circulate in human blood can provide important information about health or disease states of an individual. To gain insight into personal baselines and how protein levels vary over time, researchers within the HPA have studied the plasma proteomes of clinically healthy individuals during one year...Read more


Integration of molecular profiles in a longitudinal wellness profiling cohort

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An important aspect of precision medicine is to probe the stability in molecular profiles among healthy individuals over time. This has been published in an article in Nature Communications (Tebani et al)...Read more


The in situ expression of missing proteins in spermatogenesis

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Spermatogenesis is the process where sperm are made, and it involves thousands of genes and proteins that are activated and repressed. The function of a large proportion of these genes and proteins remains unknown and testis harbors many "missing proteins" (MPs)...Read more


Single cells within tumor and metastasis harbor genetic differences

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Over time, cells accumulate DNA mutations, that if transcribed and translated influence gene expression and/or function of the protein. The increasing number mutations in eg. genes that control cell division eventually lead formation of tumor...Read more


Antibody Validation

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There is a need for standardized validation methods for antibody specificity and selectivity. A recent article published in Nature Communications by Edfors et al. shows that the five pillars proposed by the International Working Group for Antibody Validation (IWGAV) can be used to validate antibodies for Western Blot applications in a standardized and systematic manner...Read more


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FEBS Practical and Lecture Course

May 30, 2021 - June 4, 2021

FEBS Practical and Lecture Course - A summer school aimed at graduate students, post-docs, and young independent investigators who want to learn about new techniques to explore the proteins encoded by the human genome.

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