The liver is responsible for vital biological functions in the body...Read more
In an article in "Onkologi i Sverige" (Swedish) Prof. Fredrik Pontén has written an article on the history, background and development of the Human Protein Atlas project. General strategies and historic milestones are described as well as an update of the current status of the three main parts of the current version of the Human Protein Atlas; the Normal Tissue Atlas, the Cell Atlas and the recent Pathology Atlas.
Read the full article (in Swedish)...Read more
Mammographic breast density is one of the strongest risk factors for breast cancer, but molecular understanding of how breast density relates to cancer risk is less complete. Studies of proteins in blood plasma, possibly associated with mammographic density, are well-suited as these allow large-scale analyses and might shed light on the association between breast cancer and breast density...Read more
For more than 20 years, scientists have characterised the behaviour of cells in different circumstances by analysing the expression of their genes. This is typically done at the level of gene transcripts, and their collective expression (the 'expression profile') is known as the transcriptome. These methods are very powerful, but generate massive amounts of data (mammalian cells typically express some 20,000 gene transcripts). What is needed is a method that provides a simple summary of such data. A team from Manchester, together with colleagues from Sweden, has now come up with one...Read more
Distinct mitotic substages have been identified during cell cycle progression. The different subphases are characterised by variation in protein abundance and degree of phosphorylation...Read more
June 16, 2018 - June 20, 2018
On Tuesday June 19, Jochen Schwenk will present "An update on the Human Plasma Proteome" at the XII EuPA Congress - Translating genomes into biological functions.