VIMP

GENERAL INFORMATION

? »

Gene name

VIMP

Gene description

VCP-interacting membrane protein

Protein class

Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression, most abundant in lymphoid cells.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA010025
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

VIMP (HGNC Symbol)

Synonyms

AD-015, MGC2553, SBBI8, SELS, SEPS1

Description

VCP-interacting membrane protein (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the selenoprotein family, characterized by a selenocysteine (Sec) residue at the active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

Chromosome

15

Cytoband

q26.3

Chromosome location (bp)

101270817 - 101277500

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131871 (version 78.38)

Entrez gene

55829

UniProt

Q9BQE4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BQE4

Antibodypedia

VIMP antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000398226
 
ENST00000526049
 
ENST00000528346
 
ENST00000531964
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VIMP-001 ENSP00000381282
ENST00000398226
Q9BQE4
Show all »
Show » Show » 189 21.2 No 1
VIMP-002 ENSP00000433541
ENST00000526049
Q9BQE4
Show all »
Show » Show » 189 21.2 No 1
VIMP-005 ENSP00000433803
ENST00000531964
Show » Show » 166 18.5 No 1
VIMP-006 ENSP00000434842
ENST00000528346
E9PN30
Show all »
Show » Show » 218 23.8 No 1