ALCAM

STAINING OVERVIEW

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Overall cancer tissue 
staining statistics


0%
25%
50%
75%
100%

Tissue presentation order

Histological

Alphabetical

 

Antibody HPA010926

Antibody CAB002148

Tissue

Antibody staining

Antibody staining

Colorectal cancer
Breast cancer
Prostate cancer
Ovarian cancer
Cervical cancer
Endometrial cancer
Carcinoid
Head and neck cancer
Thyroid cancer
Glioma
Lymphoma
Lung cancer
Melanoma
Skin cancer
Testis cancer
Urothelial cancer
Renal cancer
Stomach cancer
Pancreatic cancer
Liver cancer

Summary

A majority of malignancies showed moderate to strong membranous positivity. Malignant lymphomas, melanomas, testicular and renal cancers were weakly stained or negative. Many malignancies showed big variation in expression with negative, weak, moderate and strong samples within the same tumor type. Malignancies showed similar staining pattern as found in normal cells. Strong membranous staining found in many adenocarcinomas of e.g. colo-rectal, breast, prostate, cervix and endometrium. Gliomas were also mainly strong positive. Lymphomas, melanomas, testis and renal carcinomas were mainly negative. Cytoplasmic staining was also found in many samples but seems to be overstaining in most cases.Most malignant tissues displayed moderate to strong membranous immunoreactivity. Malignant lymphomas, testicular cancers and stomach cancers were mainly negative.

Validation

Uncertain: Two (or more) antibodies yielding partly similar staining patterns which are partly consistent with gene/protein characterization data or consistent with limited gene/protein characterization data
Supportive: Two (or more) antibodies yielding similar staining patterns which are partly consistent with gene/protein characterization data or consistent with limited gene/protein characterization data

Level of antibody staining/expression





High
Medium
Low
Not detected